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Article
Structure-Based Design and Synthesis of Regioisomeric Disubstituted Aminoanthraquinone Derivatives as Potential Anticancer Agents
Huang, H. S., Chiu, H. F., Yeh, P. F. & Yuan, C. L., 2004, In: Helvetica Chimica Acta. 87, 4, p. 999-1006 8 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis
Linwu, S. W., Wu, C. A., Peng, F. C. & Wang, A. H. J., Jun 15 2012, In: Biochemical Pharmacology. 83, 12, p. 1690-1699 10 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Structure-based Development of Human Interleukin-1β-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP
Kuo, W. C., Lee, C. C., Chang, Y. W., Pang, W., Chen, H. S., Hou, S. C., Lo, S. Y., Yang, A. S. & Wang, A. H. J., Feb 19 2021, In: Journal of Molecular Biology. 433, 4, 166766.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents
Chen, T. C., Wu, C. L., Lee, C. C., Chen, C. L., Yu, D. S. & Huang, H. S., Oct 20 2015, In: European Journal of Medicinal Chemistry. 103, p. 615-627 13 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases
Kuo, C. J., Guo, R. T., Lu, I. L., Liu, H. G., Wu, S. Y., Ko, T. P., Wang, A. H. J. & Liang, P. H., 2008, In: Journal of Biomedicine and Biotechnology. 2008, 1, 841312.Research output: Contribution to journal › Article › peer-review
Open Access33 Citations (Scopus) -
Structure-based pharmacophore modeling and virtual screening to identify novel inhibitors for anthrax lethal factor
Liao, H. S., Liu, H. L., Chen, W. H. & Ho, Y., Aug 2014, In: Medicinal Chemistry Research. 23, 8, p. 3725-3732 8 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Structure-Based Pharmacophore Modeling to Discover Novel CCR5 Inhibitors for HIV-1/Cancers Therapy
Lin, H. Y., Ho, Y. & Liu, H. L., Jan 2019, In: Journal of Biomedical Science and Engineering.Research output: Contribution to journal › Article › peer-review
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Structure-based strategies for synthesis, lead optimization and biological evaluation of N-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivatives as potential multi-target anticancer agents
Ali, A. A. A., Lee, Y. R., Wu, A. T. H., Yadav, V. K., Yu, D. S. & Huang, H. S., Feb 2021, In: Arabian Journal of Chemistry. 14, 2, 102884.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Structure-Based Virtual Screening and Biological Evaluation of a Calpain Inhibitor for Prevention of Selenite-Induced Cataractogenesis in an in Vitro System
Muralidharan, A. R., Selvaraj, C., Singh, S. K., Sheu, J. R., Thomas, P. A. & Geraldine, P., Aug 24 2015, In: Journal of Chemical Information and Modeling. 55, 8, p. 1686-1697 12 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E., Sung, L. C., Chao, M. W., Li, M., Zheng, J. H., Sung, T. Y., Hsieh, J. H., Yang, C. R., Lee, H. Y., Cho, E. C. & Hsu, K. C., 2022, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 37, 1, p. 226-235 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Structure-based virtual screening discovers novel kidney-type glutaminase inhibitors
Lin, L. C., Chang, H. Y., Lin, T. E., Lin, J. R., Hsia, S. M., Hsu, K. C. & Huang, T. C., Oct 2022, In: Biomedicine and Pharmacotherapy. 154, 113585.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure by NMR of Antitumor Drugs Aclacinomycin A and B Complexed to dCCGTACG)
Yang, D. & Wang, A. H. J., May 1 1994, In: Biochemistry. 33, 21, p. 6595-6604 10 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
Structure characterizations and protein resistance of chitosan membranes selectively crosslinked by poly(ethylene glycol) dimethacrylate
Cheng, C. C., Mi, F. L., Hsu, S. H. & Don, T. M., 2014, In: Cellulose. 21, 3, p. 1431-1444 14 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Structure determination of nanostructured Ni-Co films by anomalous x-ray scattering
Chow, G. M., Goh, W. C., Hwu, Y. K., Cho, T. S., Je, J. H., Lee, H. H., Kang, H. C., Noh, D. Y., Lin, C. K. & Chang, W. D., Oct 18 1999, In: Applied Physics Letters. 75, 16, p. 2503-2505 3 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Structure evolution and kinetics of thermoreversible gelation in a rigid-rod polyimide/m-cresol system
Kyu, T., Yang, J. C., Cheng, S. Z. D., Hsu, S. L. C. & Harris, F. W., Jan 1 1994, In: Macromolecules. 27, 7, p. 1861-1868 8 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans
Huang, K. Y. A., Rijal, P., Jiang, H., Wang, B., Schimanski, L., Dong, T., Liu, Y. M., Chang, P., Iqbal, M., Wang, M. C., Chen, Z., Song, R., Huang, C. C., Yang, J. H., Qi, J., Lin, T. Y., Li, A., Powell, T. J., Jan, J. T., Ma, C., & 3 others , Feb 1 2019, In: Nature Microbiology. 4, 2, p. 306-315 10 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Structure-function studies on inhibitory activity of Bungarus multicinctus protease inhibitor-like protein on matrix metalloprotease-2, and invasion and migration of human neuroblastoma SK-N-SH cells
Chou, W. M., Liu, W. H., Chen, K. C. & Chang, L. S., Feb 2010, In: Toxicon. 55, 2-3, p. 353-360 8 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Structure-guided design of anti-cancer ribonucleotide reductase inhibitors
Misko, T. A., Liu, Y. T., Harris, M. E., Oleinick, N. L., Pink, J., Lee, H. Y. & Dealwis, C. G., Jan 1 2019, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 438-450 13 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate
Williams, L. D., Egli, M., Ughetto, G., van der Marel, G. A., van Boom, J. H., Quigley, G. J., Wang, A. H. J., Rich, A. & Frederick, C. A., Sep 20 1990, In: Journal of Molecular Biology. 215, 2, p. 313-320 8 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
Structure of actinomycin D bound with (GAAGCTTC)2 and (GATGCTTC)2 and its binding to the (CAG)(n):(CTG)(n) triplet sequence as determined by NMR analysis
Lian, C., Robinson, H. & Wang, A. H. J., Sep 18 1996, In: Journal of the American Chemical Society. 118, 37, p. 8791-8801 11 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
Structure of a Derivative of Streptovaricin C Triacetate. Crystal and Molecular Structure of the Atropisomer of the Cyclic p-Bromobenzeneboronate Ester of Streptovaricin C Triacetate: Methylene Dichloride 1 : 1 Solvate
Wang, A. H. J. & Paul, I. C., Jul 1 1976, In: Journal of the American Chemical Society. 98, 15, p. 4612-4619 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Chang, T. H., Hsieh, F. L., Ko, T. P., Teng, K. H., Liang, P. H. & Wang, A. H. J., Feb 2010, In: Plant Cell. 22, 2, p. 454-467 14 p.Research output: Contribution to journal › Article › peer-review
Open Access71 Citations (Scopus) -
Structure of a NADPH-dependent blue fluorescent protein revealed the unique role of Gly176 on the fluorescence enhancement
Kao, T. H., Chen, Y., Pai, C. H., Chang, M. C. & Wang, A. H. J., Jun 2011, In: Journal of Structural Biology. 174, 3, p. 485-493 9 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Structure of an antigelling agent, l‐phenylalanyl‐glycyl‐glycyl‐d‐phenylalanine trihydrate
Fujii, S., Burley, S. K. & Wang, A. H. J., May 1987, In: Acta crystallographica. Section C, Crystal structure communications. 43, 5, p. 1008-1009 2 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Structure of an antisickling agent, l‐phenylalanyl‐3‐aminopyridinium dichloride monohydrate
Burley, S. K. & Wang, A. H. J., May 1987, In: Acta crystallographica. Section C, Crystal structure communications. 43, 5, p. 1010-1011 2 p.Research output: Contribution to journal › Article › peer-review
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Structure of an antisickling agent, N‐phenylacetyl‐l‐phenylalanine
Burley, S. K. & Wang, A. H. J., Apr 1987, In: Acta crystallographica. Section C, Crystal structure communications. 43, 4, p. 797-799 3 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Structure of a potential intermediate in cholesterol biosynthesis
Spike, T. E., Wang, A. H. J., Paul, I. C. & Schroepfer, G. J., 1974, In: Journal of the Chemical Society, Chemical Communications. 12, p. 477-478 2 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Structure of fully liganded Hb ζ2β2 strapped in a tense conformation
Safo, M. K., Ko, T. P., Abdulmalik, O., He, Z., Wang, A. H. J., Schreiter, E. R. & Russell, J. E., Oct 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 10, p. 2061-2071 11 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Structure of Stenotrophomonas maltophilia FeoA complexed with zinc: A unique prokaryotic SH3 - Domain protein that possibly acts as a bacterial ferrous iron-transport activating factor
Su, Y. C., Chin, K. H., Hung, H. C., Shen, G. H., Wang, A. H. J. & Chou, S. H., 2010, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66, 6, p. 636-642 7 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Structure of the Alkalohyperthermophilic Archaeoglobus fulgidus Lipase Contains a Unique C-Terminal Domain Essential for Long-Chain Substrate Binding
Chen, C. K. M., Lee, G. C., Ko, T. P., Guo, R. T., Huang, L. M., Liu, H. J., Ho, Y. F., Shaw, J. F. & Wang, A. H. J., Jul 24 2009, In: Journal of Molecular Biology. 390, 4, p. 672-685 14 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Structure of the DNA binding cleft of the gene 5 protein from bacteriophage fd
McPherson, A., Jurnak, F., Wang, A., Molineux, I. & Rich, A., 1979, In: Journal of Supramolecular and Cellular Biochemistry. 10, 4, p. 457-465 9 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Structure of the gene 5 DNA binding protein from bacteriophage fd and its DNA binding cleft.
McPherson, A., Wang, A., Jurnak, F., Molineux, I. & Rich, A., 1980, In: Molecular biology, biochemistry, and biophysics. 32, p. 231-240 10 p.Research output: Contribution to journal › Article › peer-review
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Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein
Skinner, M. M., Zhang, H., Leschnitzer, D. H., Guan, Y., Bellamy, H., Sweet, R. M., Gray, C. W., Konings, R. N. H., Wang, A. H. J. & Terwilliger, T. C., Mar 15 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2071-2075 5 p.Research output: Contribution to journal › Article › peer-review
Open Access114 Citations (Scopus) -
Structure of the human neutrophil elastase gene
Takahashi, H., Nukiwa, T., Yoshimura, K., Quick, C. D., States, D. J., Holmes, M. D., Whang-Peng, J., Knutsen, T. & Crystal, R. G., Jan 1 1988, In: Journal of Biological Chemistry. 263, 29, p. 14739-14747 9 p.Research output: Contribution to journal › Article › peer-review
101 Citations (Scopus) -
Structure of the Integrin VLA‐4 and its Cell‐Cell and Cell‐Matrix Adhesion Functions
Hemler, M. E., Elices, M. J., Parker, C. & Takada, Y., Apr 1990, In: Immunological Reviews. 114, 1, p. 45-65 21 p.Research output: Contribution to journal › Article › peer-review
289 Citations (Scopus) -
Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec
Safo, M. K., Ko, T. P., Musayev, F. N., Zhao, Q., Wang, A. H. J. & Archer, G. L., Apr 2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 4, p. 320-324 5 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Structure of XC6422 from Xanthomonas campestris at 1.6 Å resolution: A small serine α/β-hydrolase
Yang, C. Y., Chin, K. H., Chou, C. C., Wang, A. H. J. & Chou, S. H., Jun 2006, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62, 6, p. 498-503 6 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2
Huang, K. Y. A., Zhou, D., Tan, T. K., Chen, C., Duyvesteyn, H. M. E., Zhao, Y., Ginn, H. M., Qin, L., Rijal, P., Schimanski, L., Donat, R., Harding, A., Gilbert-Jaramillo, J., James, W., Tree, J. A., Buttigieg, K., Carroll, M., Charlton, S., Lien, C. E., Lin, M. Y., & 9 others , 2022, In: Theranostics. 27, 1, p. 1-17 17 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Structures in Physics and Neuroscience: Structural Realism and the Unity of Science
Beni, M. D. & Northoff, G., Aug 2021, In: Axiomathes. 31, 4, p. 479-495 17 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases
Cao, R., Chen, C. K. M., Guo, R. T., Wang, A. H. J. & Oldfield, E., Nov 1 2008, In: Proteins: Structure, Function and Genetics. 73, 2, p. 431-439 9 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Structures of cobalt(III)-pepleomycin and cobalt(III)-deglycopepleomycin (green fonns) determined by NMR studies
Caceres-Cortes, J., Sugiyama, H., Ikudome, K., Saito, I. & Wang, A. H. J., 1997, In: European Journal of Biochemistry. 244, 3, p. 818-828 11 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Citations (Scopus) -
Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism
Cheng, W. C., Chen, Y. F., Wang, H. J., Hsu, K. C., Lin, S. C., Chen, T. J., Yang, J. M. & Wang, W. C., Mar 16 2012, In: PLoS One. 7, 3, e33481.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Structures of human golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding
Huang, K. F., Liaw, S. S., Huang, W. L., Chia, C. Y., Lo, Y. C., Chen, Y. L. & Wang, A. H. J., Apr 8 2011, In: Journal of Biological Chemistry. 286, 14, p. 12439-12449 11 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Citations (Scopus) -
Structures of human MST3 kinase in complex with adenine, ADP and Mn 2+
Ko, T. P., Jeng, W. Y., Liu, C-I., Lai, M. D., Wu, C. L., Chang, W. J., Shr, H. L., Lu, T. J. & Wang, A. H. J., 2010, In: Acta Crystallographica Section D: Biological Crystallography. 66, 2, p. 145-154 10 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis
Chu, H. M., Guo, R. T., Lin, T. W., Chou, C. C., Shr, H. L., Lai, H. L., Tang, T. Y., Cheng, K. J., Selinger, B. L. & Wang, A. H. J., Nov 2004, In: Structure. 12, 11, p. 2015-2024 10 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Citations (Scopus) -
Structures of the hyperthermophilic chromosomal protein Sac7d in complex with DNA decamers
Ko, T. P., Chu, H. M., Chen, C. Y., Chou, C. C. & Wang, A. H. J., Aug 2004, In: Acta Crystallographica Section D: Biological Crystallography. 60, 8, p. 1381-1387 7 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Structures of the xyloglucans in the monocotyledon family Araceae (aroids)
Hsiung, S-Y., Li, J., Imre, B., Kao, M-R., Liao, H-C., Wang, D., Chen, C-H., Liang, P-H., Harris, P. J. & Hsieh, Y. S. Y., 2023, In: Planta. 257, 2Research output: Contribution to journal › Article › peer-review
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Structures of unintegrated and integrated forms of the deoxyribonucleic acid of ribonucleic acid tumour viruses
Varmus, H. E., Shank, P. R., Hughes, S. H., Kung, H. J., Heasley, S., Majors, J., Vogt, P. K. & Bishop, J. M., Dec 1 1979, In: Biochemical Society Symposia. NO. 44, p. 103-118 16 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Structures of xyloglucans in primary cell walls of gymnosperms, monilophytes (ferns sensu lato) and lycophytes
Hsieh, Y. S. Y. & Harris, P. J., Jul 2012, In: Phytochemistry. 79, p. 87-101 15 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Structure⁻Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases
Yang, C. H., Hsia, C. W., Jayakumar, T., Sheu, J. R., Hsia, C. H., Khamrang, T., Chen, Y. J., Manubolu, M. & Chang, Y., Nov 19 2018, In: International Journal of Molecular Sciences. 19, 11Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)