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• 2021

  Niche Laminin and IGF-1 Additively Coordinate the Maintenance of Oct-4 Through CD49f/IGF-1R-Hif-2α Feedforward Loop in Mouse Germline Stem Cells

  Au, H. K., Peng, S. W., Guo, C. L., Lin, C. C., Wang, Y. L., Kuo, Y. C., Law, T. Y., Ho, H. N., Ling, T. Y. & Huang, Y. H., Jul 26 2021, In: Frontiers in Cell and Developmental Biology. 9, 646644.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications

  Chen, P. C., Kuo, Y. C., Chuong, C. M. & Huang, Y. H., Jan 12 2021, In: Frontiers in Cell and Developmental Biology. 8, 625943.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  12 Citations (Scopus)

• Nicotine exhausts CD8⁺ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression

  Cheng, C. C., Lin, H. C., Chiang, Y. W., Chang, J., Sie, Z. L., Yang, B. L., Lim, K. H., Peng, C. L., Ho, A. S. & Chang, Y. F., May 2021, In: Cancer Immunology, Immunotherapy. 70, 5, p. 1351-1364 14 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma

  Su, P. H., Huang, R. L., Lai, H. C., Chen, L. Y., Weng, Y. C., Wang, C. C. & Wu, C. C., Apr 27 2021, In: Journal of Biomedical Science. 28, 1, p. 32 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Nocardial brain abscesses

  Lee, Y. W. & Liu, H. Y., Oct 14 2021, In: New England Journal of Medicine. 385, 16, e53.

  Research output: Contribution to journal › Comment/debate › peer-review

• Non-additive activity modulation during a decision making task involving tactic selection

  Braun, W., Matsuzaka, Y., Mushiake, H., Northoff, G. & Longtin, A., 2021, (Accepted/In press) In: Cognitive Neurodynamics.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Nongenomic actions of thyroid hormone: The integrin component

  Davis, P. J., Mousa, S. A. & Lin, H. Y., Jan 2021, In: Physiological Reviews. 101, 1, p. 319-352 34 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Noninferior of desflurane to sevoflurane in the occurrence of adverse respiratory events during laryngeal mask airway anesthesia in pediatrics

  Huang, P-J., Kang, Y-N., Tsai, P-S., Tai, Y-T., Huang, C-S. & Huang, C-J., Feb 2021, In: Minerva Anestesiologica. 87, 2, p. 241-242 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Non-muscular invasive bladder cancer: Re-envisioning therapeutic journey from traditional to regenerative interventions

  Shih, K. W., Chen, W. C., Chang, C. H., Tai, T. E., Wu, J. C., Huang, A. C. & Liu, M. C., Jun 1 2021, In: Aging and Disease. 12, 3, p. 868-885 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  3 Citations (Scopus)

• Notch signaling and natural killer cell infiltration in tumor tissues underlie medulloblastoma prognosis

  Liang, K. H., Chang, C. C., Wu, K. S., Yu, A. L., Sung, S. Y., Lee, Y. Y., Liang, M. L., Chen, H. H., Fen, J. J., Chao, M. E., Liao, Y. T. & Wong, T. T., Dec 2021, In: Scientific Reports. 11, 1, 23282.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Novel Algorithm for Improved Protein Classification Using Graph Similarity

  Chou, H. H., Hsu, C. T., Hsu, C. W., Yao, K. H., Wang, H. C. & Hsieh, S. Y., 2021, (Accepted/In press) In: IEEE/ACM Transactions on Computational Biology and Bioinformatics.

  Research output: Contribution to journal › Article › peer-review

• Novel app-based portable spirometer for the early detection of copd

  Lin, C. H., Cheng, S. L., Wang, H. C., Hsu, W. H., Lee, K. Y., Perng, D. W., Lin, H. I., Lin, M. S., Tsai, J. R., Wang, C. C., Lin, S. H., Wang, C. Y., Chen, C. Z., Yang, T. M., Liu, C. L., Wang, T. Y. & Lin, M. C., 2021, In: Diagnostics. 11, 5, 785.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Novel epigallocatechin-3-gallate (Egcg)-loaded mesoporous bioglass scaffolds for bone recruitment applications

  Ou, S. F., Tsao, Y. L., Lin, W. C., Wang, Y. T., Wang, L. & Fan, F. Y., Jan 1 2021, In: Applied Sciences (Switzerland). 11, 1, p. 1-9 9 p., 243.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Novel insights into the prognosis and immunological value of the slc35a (Solute carrier 35a) family genes in human breast cancer

  Ta, H. D. K., Minh Xuan, D. T., Tang, W. C., Anuraga, G., Ni, Y. C., Pan, S. R., Wu, Y. F., Fitriani, F., Putri Hermanto, E. M., Athoillah, M., Andriani, V., Ajiningrum, P. S., Wang, C. Y. & Lee, K. H., Dec 2021, In: Biomedicines. 9, 12, 1804.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Novel in Situ Synthesis of Freestanding Carbonized ZIF67/Polymer Nanofiber Electrodes for Supercapacitors via Electrospinning and Pyrolysis Techniques

  Yang, C. H., Hsiao, Y. C. & Lin, L. Y., Sep 8 2021, In: ACS Applied Materials and Interfaces. 13, 35, p. 41637-41648 12 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Novel long-acting ropeginterferon alfa-2b: Pharmacokinetics, pharmacodynamics and safety in a phase I clinical trial

  Huang, Y. W., Qin, A., Fang, J., Wang, T. F., Tsai, C. W., Lin, K. C., Teng, C. L. & Larouche, R., 2021, (Accepted/In press) In: British Journal of Clinical Pharmacology. 88, 5, p. 2396-2407 12 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Novel nfκb inhibitor sc75741 mitigates chondrocyte degradation and prevents activated fibroblast transformation by modulating mir‐21/gdf‐5/sox5 signaling

  Weng, P. W., Yadav, V. K., Pikatan, N. W., Fong, I. H., Lin, I. H., Yeh, C. T. & Lee, W. H., Oct 1 2021, In: International journal of molecular sciences. 22, 20, 11082.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Novel pd-l1 mab hc16 reveals upregulation of pd-l1 in bac subtype

  Su, B. C., Ting, C. H., Lee, K. Y., Wu, S. M., Feng, P. H., Chan, Y. F. & Chen, J. Y., Jan 2021, In: Histology and Histopathology. 36, 1, p. 77-89 13 p.

  Research output: Contribution to journal › Article › peer-review

• Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease

  Cheng, L. C., Kao, T. J., Phan, N. N., Chiao, C. C., Yen, M. C., Chen, C. F., Hung, J. H., Jiang, J. Z., Sun, Z., Wang, C. Y. & Hsu, H. P., Feb 2021, In: Medicine. 100, 7, p. e24321

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• Nsc828779 alleviates renal tubulointerstitial lesions involving interleukin-36 signaling in mice

  Yang, S. R., Hung, S. C., Chu, L. J., Hua, K. F., Wei, C. W., Tsai, I. L., Kao, C. C., Sung, C. C., Chu, P., Wu, C. Y., Chen, A., Wu, A. T. H., Liu, F. C., Huang, H. S. & Ka, S. M., Nov 2021, In: Cells. 10, 11, 3060.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance

  Wang, H., Wang, Q., Cai, G., Duan, Z., Nugent, Z., Huang, J., Zheng, J., Borowsky, A. D., Li, J. J., Liu, P., Kung, H. J., Murphy, L., Chen, H. W. & Wang, J., 2021, (Accepted/In press) In: Acta Pharmaceutica Sinica B.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Nurses’ barriers to caring for patients with COVID-19: a qualitative systematic review

  Joo, J. Y. & Liu, M. F., Jun 2021, In: International Nursing Review. 68, 2, p. 202-213 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  43 Citations (Scopus)

• Nursing manpower forecast for cancer patients

  Chung, M. H., Hung, K. C., Chiou, J. F., Fang, H. F. & Chiu, C. H., Apr 2021, In: Computer Methods and Programs in Biomedicine. 201, 105967.

  Research output: Contribution to journal › Article › peer-review

• Obesity alters ovarian folliculogenesis through disrupted angiogenesis from increased IL-10 production

  Yang, P. K., Chou, C. H., Huang, C. C., Wen, W. F., Chen, H. F., Shun, C. T., Ho, H. N. & Chen, M. J., Jul 2021, In: Molecular Metabolism. 49, 101189.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Obesity and Mortality Among Patients Diagnosed With COVID-19: A Systematic Review and Meta-Analysis

  Poly, T. N., Islam, M. M., Yang, H. C., Lin, M. C., Jian, W. S., Hsu, M. H. & Jack Li, Y. C., Feb 5 2021, In: Frontiers in Medicine. 8, 620044.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  51 Citations (Scopus)

• Obesity Exacerbates Irritable Bowel Syndrome-Related Sleep and Psychiatric Disorders in Women With Polycystic Ovary Syndrome

  Tseng, P. H., Chiu, H. M., Tu, C. H., Wu, M. S., Ho, H. N. & Chen, M. J., Nov 2021, In: Frontiers in Endocrinology. 12, 779456.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Obtaining high-resolution pathology images using a mobile device

  Yeh, M. C. H., Yen, H., Tsai, T. Y., Liu, H. N. & Huang, Y. C., Sep 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. e147-e148 2 p.

  Research output: Contribution to journal › Article › peer-review

• Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis

  Truong, V., Cheng, P. Z., Lee, H. C., Lane, T. J., Hsu, T. Y. & Duncan, N. W., Feb 28 2021, In: Psychiatry Research - Neuroimaging. 308, 111238.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Occupation-level automation probability is associated with psychosocial work conditions and workers' health: A multilevel study

  Cheng, W. J., Pien, L. C. & Cheng, Y., Feb 2021, In: American Journal of Industrial Medicine. 64, 2, p. 108-117 10 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Occurrence of thermally induced glycidyl esters and 3-monochloropropane-1,2-diol esters in refined oils and pressed oils manufactured by different processes and associated with human health risks in Taiwan

  Chen, H., Tsao, C. H., Chang, Y. H. & Lee, W. J., Oct 30 2021, In: Food Chemistry. 360, 130053.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study

  Chen, Y. C., Dang, L. H., Chen, L. C., Chang, C. C., Han, D. Y., Hsu, C. H., Ding, Y. F., Su, C. H. & Hung, S. H., Jan 2021, In: Journal of the Formosan Medical Association. 120, 1 Pt 2, p. 318-326 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• OGT-rearranged Acral Mesenchymal Neoplasms: An Emerging Entity with an Expanding Pathologic and Molecular Spectrum

  Lee, J. C., Hsieh, T. H. & Kao, Y. C., 2021, (Accepted/In press) In: American Journal of Surgical Pathology. 001679.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Omega-3 Polyunsaturated Fatty Acid Supplementation in Patients with Lower Extremity Arterial Disease

  Su, M. I., Cheng, Y. C., Huang, Y. C. & Liu, C. W., 2021, (Accepted/In press) In: Journal of the American College of Nutrition.

  Research output: Contribution to journal › Article › peer-review

• Once-daily tenofovir disoproxil fumarate in treatment-naive Taiwanese patients with chronic hepatitis B and minimally raised alanine aminotransferase (TORCH-B): a multicentre, double-blind, placebo-controlled, parallel-group, randomised trial

  Hsu, Y. C., Chen, C. Y., Chang, I. W., Chang, C. Y., Wu, C. Y., Lee, T. Y., Wu, M. S., Bair, M. J., Chen, J. J., Chen, C. C., Tseng, C. H., Tai, C. M., Huang, Y. T., Ku, W. H., Mo, L. R. & Lin, J. T., Jun 2021, In: The Lancet Infectious Diseases. 21, 6, p. 823-833 11 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Oncologic Outcomes of Radical Prostatectomy and High-Dose Intensity-Modulated Radiotherapy with Androgen-Deprivation Therapy for Relatively Young Patients with Unfavorable Intermediate-Risk Prostate Adenocarcinoma

  Wu, S-Y., Chang, S-C., Chen, C-I. & Huang, C-C., Mar 25 2021, In: Cancers. 13, 7

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• One-pot Bi-enzymatic cascade synthesis of novel ganoderma triterpenoid saponins

  Chang, T. S., Chiang, C. M., Wang, T. Y., Tsai, Y. L., Wu, Y. W., Ting, H. J. & Wu, J. Y., May 2021, In: Catalysts. 11, 5, 580.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration

  Wu, M. H., Wang, W., Chao, F. C., Hsieh, C. M., Chen, L. C., Lin, H. L., Ho, H. O., Huang, T. J. & Sheu, M. T., Feb 2021, In: Carbohydrate Polymers. 254, 117270.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Online critical review classification in response strategy and service provider rating: Algorithms from heuristic processing, sentiment analysis to deep learning

  Zhu, J. J., Chang, Y-C., Ku, C-H., Li, S. Y. & Chen, C-J., 2021, In: Journal of Business Research. 129, p. 860-877 18 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Open-Book Pelvic Fracture

  Tai, T-H. & Chen, C-Y., Jan 7 2021, In: The New England journal of medicine. 384, 1, p. 60

  Research output: Contribution to journal › Article › peer-review

• Opioid prescribing among new users for non-cancer pain in the USA, Canada, UK, and Taiwan: A population-based cohort study

  Jani, M., Girard, N., Bates, D. W., Buckeridge, D. L., Sheppard, T., Li, J., Iqbal, U., Vik, S., Weaver, C., Seidel, J., Dixon, W. G. & Tamblyn, R., Nov 2021, In: PLoS Medicine. 18, 11, e1003829.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Optimal combination of band-pass filters for theanine content prediction using near-infrared spectroscopy

  Ong, P., Chen, S., Tsai, C. Y. & Chuang, Y. K., Jun 2021, In: Infrared Physics and Technology. 115, 103701.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Optimal lymph node yield for survival prediction in rectal cancer patients after neoadjuvant therapy

  Lin, Y. M., Chou, C. L., Kuo, Y. H., Wu, H. C., Tsai, C. J., Ho, C. H., Chen, Y. C., Yang, C. C. & Lin, C. W., 2021, In: Cancer Management and Research. 13, p. 8037-8047 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Optimal substrate modification strategies using catheter ablation in patients with persistent atrial fibrillation: 3-year follow-up outcomes

  Hsieh, Y. C., Lin, Y. J., Lo, M. T., Chen, Y. Y., Lin, C. Y., Lin, C., Chung, F. P., Lo, L. W., Chang, S. L., Chao, T. F., Hu, Y. F., Tuan, T. C., Liao, J. N., Wu, C. I., Liu, C. M., Vicera, J. J. B., Chen, C. C., Chin, C. G., Lugtu, I. C. & Chen, S. A., 2021, (Accepted/In press) In: Journal of Cardiovascular Electrophysiology.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Optimal timing and effect of music therapy in patients with burn injuries: Systematic review and meta-analysis of randomized controlled trials

  Wu, T. J., Chen, K. H., Chiu, W. K., Lee, C. L., Wang, H. J., Kang, Y. N. & Chen, C., 2021, (Accepted/In press) In: Burns.

  Research output: Contribution to journal › Article › peer-review

• Optimization and development of selective histone deacetylase inhibitor (Mpt0b291)-loaded albumin nanoparticles for anticancer therapy

  Putri, A. D., Chen, P. S., Su, Y. L., Lin, J. P., Liou, J. P. & Hsieh, C. M., Oct 2021, In: Pharmaceutics. 13, 10, 1728.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Optimization shape-memory situations of a stimulus responsive composite material

  Lin, W. C., Fan, F. Y., Cheng, H. C., Lin, Y., Shen, Y. K., Lai, J. S., Wang, L. & Ruslin, M., Mar 1 2021, In: Polymers. 13, 5, p. 1-19 19 p., 697.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Optimized micro-pattern design and fabrication of a light guide plate using micro-injection molding

  Fan, F. Y., Chou, H. H., Lin, W. C., Huang, C. F., Lin, Y., Shen, Y. K. & Ruslin, M., Dec 1 2021, In: Polymers. 13, 23, 4244.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Oral microbiota changes in elderly patients, an indicator of alzheimer’s disease

  Wu, Y. F., Lee, W. F., Salamanca, E., Yao, W. L., Su, J. N., Wang, S. Y., Hu, C. J. & Chang, W. J., Apr 2021, In: International journal of environmental research and public health. 18, 8, 4211.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Oral paclitaxel with encequidar compared to intravenous paclitaxel in patients with advanced cancer: A randomised crossover pharmacokinetic study

  Jackson, C. G. C. A., Hung, T., Segelov, E., Barlow, P., Prenen, H., McLaren, B., Hung, N. A., Clarke, K., Chao, T. Y., Dai, M. S., Yeh, H. T., Cutler, D. L., Kramer, D., He, J., Zhi, J., Chan, W. K., Kwan, R. & Deva, S., Dec 2021, In: British Journal of Clinical Pharmacology. 87, 12, p. 4670-4680 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Oral tegafur-uracil as a metronomic therapy in stage IVa and IVb cancer of the oral cavity

  Huang, W. Y., Ho, C. L., Chao, T. Y., Lee, J. C. & Chen, J. H., Nov 1 2021, In: American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 42, 6, 103156.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)