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• 2015

  Detection of reactive oxygen species during the cell cycle under normal culture conditions using a modified fixed-sample staining method

  Hsieh, C. Y., Chen, C. L., Yang, K. C., Ma, C. T., Choi, P. C. & Lin, C. F., Mar 4 2015, In: Journal of Immunoassay and Immunochemistry. 36, 2, p. 149-161 13 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Determinants and characteristics of angle-closure disease in an elderly Chinese population

  Ko, Y. C., Liu, C. J., Hsu, W. M., Cheng, C. Y., Kuang, T. M. & Chou, P., Apr 1 2015, In: Ophthalmic Epidemiology. 22, 2, p. 109-115 7 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Determinants of end-of-life expenditures in patients with oral cancer in Taiwan: A population-based study

  Lee, C. C., Chang, T. S., Wu, C. J., Yang, C. C. & Chen, P. C., May 6 2015, In: PLoS One. 10, 5, e0126482.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Determinants of Hospital Death for Taiwanese Pediatric Cancer Decedents, 2001-2010

  Hung, Y-N., Liu, T. W. & Tang, S. T., Nov 2015, In: Journal of Pain and Symptom Management. 50, 5, p. 685-692 8 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Determinants of workplace violence against clinical physicians in hospitals

  Wu, J. C., Tung, T. H., Chen, P. Y., Chen, Y. L., Lin, Y. W. & Chen, F. L., Jan 1 2015, In: Journal of Occupational Health. 57, 6, p. 540-547 8 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Determining the N-terminal orientations of recombinant transmembrane proteins in the Escherichia coli plasma membrane

  Lee, C. H., Chou, C. C., Hsu, M. F. & Wang, A. H. J., Oct 14 2015, In: Scientific Reports. 5, 15086.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Developing a mobile electronic d2b checklist for treatment of st elevation myocardial infarction patients who need a primary coronary intervention

  Lin, H. J., Hsu, M. H., Huang, C. C., Liu, C. F., Tan, C. K., Chou, S. L., Huang, S. Y. & Chen, C. J., Apr 1 2015, In: Telemedicine and e-Health. 21, 4, p. 274-280 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Developing an ICF core set for sub-acute stages of spinal cord injury in Taiwan: A preliminary study

  Chen, H. C., Yen, T. H., Chang, K. H., Lin, Y-N., Wang, Y. H. & Liou, T. H., Jan 1 2015, In: Disability and Rehabilitation. 37, 1, p. 51-55 5 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Developing a QSAR model for hepatotoxicity screening of the active compounds in traditional Chinese medicines

  Huang, S. H., Tung, C. W., Fülöp, F. & Li, J. H., Apr 1 2015, In: Food and Chemical Toxicology. 78, p. 71-77 7 p.

  Research output: Contribution to journal › Article › peer-review
  53 Citations (Scopus)

• Development and application of gravity acceleration measurement in running kinematic analysis

  Lin, S. P., Sung, W. H., Kuo, T. B. J. & Chen, J. J., Jan 1 2015, In: ICIC Express Letters. 9, 5, p. 1349-1354 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering

  Chen, Y. C., Chen, R. N., Jhan, H. J., Liu, D. Z., Ho, H. O., Mao, Y., Kohn, J. & Sheu, M. T., Sep 1 2015, In: Tissue Engineering - Part C: Methods. 21, 9, p. 971-986 16 p.

  Research output: Contribution to journal › Article › peer-review
  63 Citations (Scopus)

• Development and psychometric evaluation of the Chinese Feeding Difficulty Index (Ch-FDI) for people with dementia

  Liu, M. F., Miao, N. F., Chen, I. H., Lin, Y-K., Ho, M. H., Roberts, B. L. & Chang, C. C., Jul 21 2015, In: PLoS ONE. 10, 7, 0133716.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Development and testing of X-ray imaging-enhanced poly-L-lactide bone screws

  Chang, W. J., Pan, Y. H., Tzeng, J. J., Wu, T. L., Fong, T. H., Feng, S-W. & Huang, H. M., Oct 14 2015, In: PLoS One. 10, 10, 0140354.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma

  Chepyala, D., Tsai, I. L., Sun, H. Y., Lin, S. W. & Kuo, C. H., Feb 1 2015, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 980, p. 48-54 7 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Development and validation of the health literacy assessment tool for older people in Taiwan: Potential impacts of cultural differences

  Chung, M. H., Chen, L. K., Peng, L. N. & Chi, M. J., Sep 1 2015, In: Archives of Gerontology and Geriatrics. 61, 2, p. 289-295 7 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Development and validation of the ICF-CY-Based Functioning Scale of the Disability Evaluation System-Child Version in Taiwan

  Hwang, A. W., Yen, C. F., Liou, T. H., Bedell, G., Granlund, M., Teng, S. W., Chang, K. H., Chi, W. C. & Liao, H. F., Dec 1 2015, In: Journal of the Formosan Medical Association. 114, 12, p. 1170-1180 11 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Development and validation of the Simulation Learning Effectiveness Inventory

  Chen, S. L., Huang, T. W., Liao, I. C. & Liu, C., Oct 1 2015, In: Journal of Advanced Nursing. 71, 10, p. 2444-2453 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Development of a computerized digit vigilance test and validation in patients with stroke

  Yang, C. M., Lin, G. H., Chen, M. H., Hsueh, I. P. & Hsieh, C. L., Apr 1 2015, In: Journal of Rehabilitation Medicine. 47, 4, p. 311-317 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Development of a method for manufacturing customized nasal mask cushion for CPAP therapy

  Hsu, D. Y., Cheng, Y. L., Bien, M-Y. & Lee, H-C., Dec 1 2015, In: Australasian Physical and Engineering Sciences in Medicine. 38, 4, p. 657-664 8 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Development of an enzymatic assay system of d-lactate using d-lactate dehydrogenase and a UV-LED fluorescent spectrometer

  Chen, C. M., Chen, S. M., Chien, P. J. & Yu, H. Y., Mar 2 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 116, p. 150-155 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Development of lattice-inserted 5-Fluorouracil-hydroxyapatite nanoparticles as a chemotherapeutic delivery system

  Tseng, C. L., Chen, J. C., Wu, Y. C., Fang, H. W., Lin, F. H. & Tang, T. P., Oct 1 2015, In: Journal of Biomaterials Applications. 30, 4, p. 388-397 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Development of telmisartan in the therapy of spinal cord injury: Pre-clinical study in rats

  Lin, C. M., Tsai, J. T., C Hang, C. K., Cheng, J. T. & Lin, J. W., Aug 14 2015, In: Drug Design, Development and Therapy. 9, p. 4709-4717 9 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Diabetic polyneuropathy and the risk of developing diabetic retinopathy: A nationwide, population-based study

  Lin, I-C., Wang, Y-H., Lin, C. L., Chang, Y. J., Lee, S. H. & Wang, I. J., Dec 1 2015, In: Acta Ophthalmologica. 93, 8, p. 713-718 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Diallyl trisulphide inhibits adipogenesis in 3T3-L1 adipocytes through lipogenesis, fatty acid transport, and fatty acid oxidation pathways

  Chang, W. T., Wu, C. H. & Hsu, C. L., Jun 1 2015, In: Journal of Functional Foods. 16, p. 414-422 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Dietary saturated fatty acids reduce hepatic lipid accumulation but induce fibrotic change in alcohol-fed rats

  Chen, Y. L., Peng, H. C., Wang, X. D. & Yang, S-C., Jun 2015, In: Hepatobiliary surgery and nutrition. 4, 3, p. 172-83 12 p.

  Research output: Contribution to journal › Article › peer-review

• Differences in cortisol profiles and circadian adjustment time between nurses working night shifts and regular day shifts: A prospective longitudinal study

  Niu, S. F., Chung, M. H., Chu, H., Tsai, J. C., Lin, C. C., Liao, Y. M., Ou, K. L., O'Brien, A. P. & Chou, K. R., Jul 1 2015, In: International Journal of Nursing Studies. 52, 7, p. 1193-1201 9 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Differential effects of olanzapine and clozapine on plasma levels of adipocytokines and total ghrelin

  Lu, M. L., Wang, T. N., Lin, T. Y., Shao, W. C., Chang, S. H., Chou, J. Y., Ho, Y. F., Liao, Y. T. & Chen, V. C. H., Apr 3 2015, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 58, p. 47-50 4 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Differentiating disease subtypes by using pathway patterns constructed from gene expressions and protein networks

  Hung, F. H. & Chiu, H. W., Nov 4 2015, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Institute of Electrical and Electronics Engineers Inc., Vol. 2015-November. p. 6519-6522 4 p. 7319886

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Differentiation effects of platelet-rich plasma concentrations on synovial fluid mesenchymal stem cells from pigs cultivated in alginate complex hydrogel

  Tang, H. C., Chen, W. C., Chiang, C. W., Chen, L. Y., Chang, Y. C. & Chen, C. H., Aug 7 2015, In: International journal of molecular sciences. 16, 8, p. 18507-18521 15 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Different patterns of heart rate variability during acute withdrawal in alcohol dependent patients with and without comorbid anxiety and/or depression

  Chen, T. Y., Chang, C. C., Tzeng, N. S., Kuo, T. B. J., Huang, S. Y., Lu, R. B. & Chang, H. A., Jul 28 2015, In: Journal of Psychophysiology. 29, 3, p. 87-98 12 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Different spontaneous breathing trials in patients with atrial fibrillation

  Tseng, Y. H., Tseng, Y. C., Hsu, H. S. & Chang, S. C., Jan 1 2015, In: Revista Portuguesa de Pneumologia. 21, 5

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Dipeptidyl peptidase-4 inhibition attenuates arrhythmias via a protein kinase a-dependent pathway in infarcted hearts

  Lee, T-M., Chen, W. T. & Chang, N. C., Oct 23 2015, In: Circulation Journal. 79, 11, p. 2461-2470 10 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice

  Lu, H. Y., Huang, C. Y., Shih, C. M., Chang, W. H., Tsai, C. S., Lin, F. Y. & Shih, C. C., Apr 14 2015, In: PLoS ONE. 10, 4, e0121077.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Direct coating of culture medium from cells secreting classical swine fever virus E2 antigen on ELISA plates for detection of E2-specific antibodies

  Cheng, T. C., Pan, C. H., Chen, C. S., Chuang, K. H., Chuang, C. H., Huang, C. C., Chu, Y. Y., Yang, Y. C., Chu, P. Y., Kao, C. H., Hsieh, Y. C. & Cheng, T. L., Jul 1 2015, In: Veterinary Journal. 205, 1, p. 107-109 3 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Direct mechanoelectrical coupling during manual chest compression for asystole

  Chen, C. Y., Lin, L. Y. & Lin, J. L., Jan 1 2015, In: Heart Rhythm. 12, 1, p. 252-253 2 p.

  Research output: Contribution to journal › Article › peer-review

• Direct medical cost of stroke in Singapore

  Ng, C. S., Toh, M. P. H. S., Ng, J. & Ko, Y., Oct 1 2015, In: International Journal of Stroke. 10, A100, p. 75-82 8 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Direct medical cost of type 2 diabetes in Singapore

  Ng, C. S., Toh, M. P. H. S., Ko, Y. & Lee, J. Y. C., Mar 27 2015, In: PLoS One. 10, 3, e0122795.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Disablement

  Janke, M. C., Chen, T-Y. & Young, T. L., 2015, The Encyclopedia of Adulthood and Aging.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Discovering Latent Semantics in Web Documents Using Fuzzy Clustering

  Chiang, I-J., Liu, C. C. H., Tsai, Y. H. & Kumar, A., Dec 1 2015, In: IEEE Transactions on Fuzzy Systems. 23, 6, p. 2122-2134 13 p., 7042824.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries

  Tung, C. P., Chen, I. C., Yu, C. M., Peng, H. P., Jian, J. W., Ma, S. H., Lee, Y. C., Jan, J. T. & Yang, A. S., Oct 12 2015, In: Scientific Reports. 5, 15053.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Discovery of 5-(2′,4′-difluorophenyl)-salicylanilides as new inhibitors of receptor activator of NF-κ°B ligand (RANKL)-induced osteoclastogenesis

  Lee, C. C., Liu, F. L., Chen, C. L., Chen, T. C., Chang, D. M. & Huang, H. S., May 25 2015, In: European Journal of Medicinal Chemistry. 98, p. 115-126 12 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Discovery of akt kinase inhibitors through structure-based virtual screening and their evaluation as potential anticancer agents

  Chuang, C. H., Cheng, T. C., Leu, Y. L., Chuang, K. H., Tzou, S. C. & Chen, C. S., Feb 2 2015, In: International journal of molecular sciences. 16, 2, p. 3202-3212 11 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Discovery of highly potent tyrosinase inhibitor, T1, with significant anti-melanogenesis ability by zebrafish in vivo assay and computational molecular modeling

  Chen, W-C., Tseng, T-S., Hsiao, N-W., Lin, Y-L., Wen, Z-H., Tsai, C-C., Lee, Y-C., Lin, H-H. & Tsai, K-C., 2015, In: Scientific Reports. 5

  Research output: Contribution to journal › Article › peer-review
  102 Citations (Scopus)

• Discovery of novel 5α-reductase type II inhibitors by pharmacophore modelling, virtual screening, molecular docking and molecular dynamics simulations

  Wang, J. L., Liu, H. L., Zhou, Z. L., Chen, W. H. & Ho, Y., Mar 4 2015, In: Molecular Simulation. 41, 4, p. 287-297 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Discovery of Potent Cysteine-Containing Dipeptide Inhibitors against Tyrosinase: A Comprehensive Investigation of 20 × 20 Dipeptides in Inhibiting Dopachrome Formation

  Tseng, T-S., Tsai, K-C., Chen, W-C., Wang, Y-T., Lee, Y-C., Lu, C-K., Don, M-J., Chang, C-Y., Lee, C-H., Lin, H-H., Hsu, H-J. & Hsiao, N-W., 2015, In: Journal of Agricultural and Food Chemistry. 63, 27, p. 6181-6188 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Discovery of specific inhibitors for intestinal E. coli β -glucuronidase through in silico virtual screening

  Cheng, T. C., Chuang, K. H., Roffler, S. R., Cheng, K. W., Leu, Y. L., Chuang, C. H., Huang, C. C., Kao, C. H., Hsieh, Y. C., Chang, L. S., Cheng, T. L. & Chen, C. S., 2015, In: Scientific World Journal. 2015, 740815.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Disrupted thalamic resting-state functional networks in schizophrenia

  Wang, H. L. S., Rau, C. L., Li, Y. M., Chen, Y. P. & Yu, R., Feb 25 2015, In: Frontiers in Behavioral Neuroscience. 9, FEB

  Research output: Contribution to journal › Article › peer-review

  Open Access
  38 Citations (Scopus)

• Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

  Liu, K. Y., Shyu, Y. C., Barbaro, B. A., Lin, Y. T., Chern, Y., Thompson, L. M., Shen, C. K. J. & Marsh, J. L., 2015, In: Human Molecular Genetics. 24, 6, p. 1602-1616 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  54 Citations (Scopus)

• Distinct MR Imaging Features of Triple-Negative Breast Cancer with Brain Metastasis

  Yeh, R. H., Yu, J. C., Chu, C. H., Ho, C. L., Kao, H. W., Liao, G. S., Chen, H. W., Kao, W. Y., Yu, C. P., Chao, T. Y. & Dai, M. S., May 1 2015, In: Journal of Neuroimaging. 25, 3, p. 474-481 8 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Distinct roles for GABA across multiple timescales in mammalian circadian timekeeping

  DeWoskin, D., Myung, J., Belle, M. D. C., Piggins, H. D., Takumi, T. & Forger, D. B., Jul 21 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 29, p. E3911-E3919

  Research output: Contribution to journal › Article › peer-review
  93 Citations (Scopus)