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  Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents

  Chen, T. C., Guh, J. H., Hsu, H. W., Chen, C. L., Lee, C. C., Wu, C. L., Lee, Y. R., Lin, J. J., Yu, D. S. & Huang, H. S., Dec 2019, In: Arabian Journal of Chemistry. 12, 8

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents

  Sandhu, H. S., Sapra, S., Gupta, M., Nepali, K., Gautam, R., Yadav, S., Kumar, R., Jachak, S. M., Chugh, M., Gupta, M. K., Suri, O. P. & Dhar, K. L., Aug 1 2010, In: Bioorganic and Medicinal Chemistry. 18, 15, p. 5626-5633 8 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Synthesis and biological evaluation of chalcones having heterosubstituent(s)

  Sweety, Kumar, S., Nepali, K., Sapra, S., Suri, O. P., Dhar, K. L., Sarma, G. S. & Saxena, A. K., Nov 1 2010, In: Indian Journal of Pharmaceutical Sciences. 72, 6, p. 801-806 6 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Synthesis and biological evaluation of lovastatin-derived aliphatic hydroxamates that induce reactive oxygen species

  Lin, R. K., Lin, Y. F., Hsu, M. J., Hsieh, C. L., Wang, C. Y., Huang, C. C. & Huang, W. J., 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 22, p. 5528-5533 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Synthesis and biological evaluation of naphthalene, furan and pyrrole based chalcones as cytotoxic and antimicrobial agents

  Budhiraja, A., Kadian, K., Kaur, M., Aggarwal, V., Garg, A., Sapra, S., Nepali, K., Suri, O. P. & Dhar, K. L., Sept 1 2012, In: Medicinal Chemistry Research. 21, 9, p. 2133-2140 8 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Synthesis and Biological Evaluation of Novel bis-Aziridinylnaphthoquinone Derivatives

  Huang, S. T., Kuo, H. S., Lin, C-M., Tsai, H. D., Peng, Y. C., Chen, C-T. & Lin, Y. L., 2002, In: Oncology Research. 13, 4, p. 199-204 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Synthesis and Biological Evaluation of ortho-Aryl N-Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform-Selective Inhibitors

  Huang, W. J., Wang, Y. C., Chao, S. W., Yang, C. Y., Chen, L. C., Lin, M. H., Hou, W. C., Chen, M. Y., Lee, T. L., Yang, P. & Chang, C. I., Oct 2012, In: ChemMedChem. 7, 10, p. 1815-1824 10 p.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)

• Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors

  Hsu, K-C., Chu, J-C., Tseng, H-J., Liu, C-I., Wang, H-C., Lin, T. E., Lee, H-S., Hsin, L-W., Wang, A. H-J., Lin, C-H. & Huang, W-J., Jul 5 2021, In: European Journal of Medicinal Chemistry. 219, 113419.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Synthesis and biological evaluation of some 1-substituted 3-(2-perimidyl)ureas

  Liu, K. C. & Huang, H. S., 1988, In: Archiv der Pharmazie. 321, 7, p. 425-426 2 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Synthesis and characterization of a novel chitosan-based network prepared using naturally occurring crosslinker

  Mi, F. L., Sung, H. W. & Shyu, S. S., Aug 1 2000, In: Journal of Polymer Science, Part A: Polymer Chemistry. 38, 15, p. 2804-2814 11 p.

  Research output: Contribution to journal › Article › peer-review
  223 Citations (Scopus)

• Synthesis and characterization of a novel chitosan-gelatin bioconjugate with fluorescence emission

  Mi, F. L., Mar 2005, In: Biomacromolecules. 6, 2, p. 975-987 13 p.

  Research output: Contribution to journal › Article › peer-review
  145 Citations (Scopus)

• Synthesis and characterization of a novel glycoconjugated macromolecule

  Mi, F. L., Yu, S. H., Peng, C. K., Sung, H. W., Shyu, S. S., Liang, H. F., Huang, M. F. & Wang, C. C., May 31 2006, In: Polymer. 47, 12, p. 4348-4358 11 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Synthesis and characterization of biodegradable TPP/genipin co-crosslinked chitosan gel beads

  Mi, F. L., Sung, H. W., Shyu, S. S., Su, C. C. & Peng, C. K., Sept 18 2003, In: Polymer. 44, 21, p. 6521-6530 10 p.

  Research output: Contribution to journal › Article › peer-review
  226 Citations (Scopus)

• Synthesis and characterization of dual-sensitive fluorescent nanogels for enhancing drug delivery and tracking intracellular drug delivery

  Wu, S. Y., Debele, T. A., Kao, Y. C. & Tsai, H. C., May 19 2017, In: International journal of molecular sciences. 18, 5, 1090.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Synthesis and characterization of electrochromic plate-like tungsten oxide films by acidic treatment of electrochemical anodized tungsten

  Wang, C. K., Lin, C. K., Wu, C. L., Wang, S. C. & Huang, J. L., 2013, In: Electrochimica Acta. 112, p. 24-31 8 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Synthesis and characterization of Fe₃O₄/polypyrrole/carbon nanotube composites with tunable microwave absorption properties: Role of carbon nanotube and polypyrrole content

  Yang, R. B., Reddy, P. M., Chang, C. J., Chen, P. A., Chen, J. K. & Chang, C. C., Feb 1 2016, In: Chemical Engineering Journal. 285, p. 497-507 11 p.

  Research output: Contribution to journal › Article › peer-review
  252 Citations (Scopus)

• Synthesis and characterization of Gd-DTPA/fucoidan/peptide complex nanoparticle and in vitro magnetic resonance imaging of inflamed endothelial cells

  Cheng, T. M., Li, R., Kao, Y. C. J., Hsu, C. H., Chu, H. L., Lu, K. Y., Changou, C. A., Chang, C. C., Chang, L. H., Tsai, M. L. & Mi, F. L., Sept 2020, In: Materials Science and Engineering C. 114, 111064.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Synthesis and Characterization of Gold/Polypyrrole Core-Shell Nanocomposites and Elemental Gold Nanoparticles Based on the Gold-Containing Nanocomplexes Prepared by Electrochemical Methods in Aqueous Solutions

  Liu, Y. C. & Chuang, T. C., Nov 13 2003, In: Journal of Physical Chemistry B. 107, 45, p. 12383-12386 4 p.

  Research output: Contribution to journal › Article › peer-review
  134 Citations (Scopus)

• Synthesis and characterization of magnetic nanoparticles coated with polystyrene sulfonic acid for biomedical applications

  Chen, B. W., He, Y. C., Sung, S. Y., Le, T. T. H., Hsieh, C. L., Chen, J. Y., Wei, Z. H. & Yao, D. J., Jan 31 2020, In: Science and Technology of Advanced Materials. 21, 1, p. 471-481 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Citations (Scopus)

• Synthesis and characterization of melatonin-loaded chitosan microparticles promote differentiation and mineralization in preosteoblastic cells

  Huang, R. Y., Hsiao, P. Y., Mau, L. P., Tsai, Y. W. C., Cochran, D. L., Weng, P. W., Cheng, W. C., Chung, C. H. & Huang, Y. C., Dec 2020, In: Journal of Oral Implantology. 46, 6, p. 562-570 9 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Synthesis and Characterization of PANI-MWCNTs Supported Nano Hybrid Electrocatalysts

  Chiou, Y. J., Chung, M-Y., Lin, H. M., Liu, H-Y., Borodzinski, A., Stobinski, L., Lin, C. K. & Krzysztof Ryszard Kupiec, 2017, In: Journal of Material Sciences and Engineering. p. 1-8

  Research output: Contribution to journal › Article › peer-review

• Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane

  Lee, S. Y., Wu, S. C., Chen, H., Tsai, L. L., Tzeng, J. J., Lin, C. H. & Lin, Y. M., Jan 1 2018, In: BioMed Research International. 2018, p. 3240571 3240571.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Synthesis and characterization of positive-charge functionalized mesoporous silica nanoparticles for oral drug delivery of an anti-inflammatory drug

  Lee, C. H., Lo, L. W., Mou, C. Y. & Yang, C. S., Oct 23 2008, In: Advanced Functional Materials. 18, 20, p. 3283-3292 10 p.

  Research output: Contribution to journal › Article › peer-review
  191 Citations (Scopus)

• Synthesis and cytotoxicity of 9-alkoxy-1,5-dichloroanthracene derivatives in murine and human cultured tumor cells

  Huang, H-S., Chiou, J-F., Chiu, H-F., Chen, R-F. & Lai, Y-L., Jan 2002, In: Archiv der Pharmazie. 335, 1, p. 33-8 6 p.

  Research output: Contribution to journal › Article › peer-review

  10 Citations (Scopus)

• Synthesis and cytotoxicity studies of 3,5-diaryl N-acetyl pyrazoline - Isatin hybrids

  Sharma, M., Sharma, S., Buddhiraja, A., Saxena, A. K., Nepali, K. & Bedi, P. M. S., Oct 1 2014, In: Medicinal Chemistry Research. 23, 10, p. 4337-4344 8 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones

  Shchekotikhin, A. E., Glazunova, V. A., Dezhenkova, L. G., Luzikov, Y. N., Sinkevich, Y. B., Kovalenko, L. V., Buyanov, V. N., Balzarini, J., Huang, F. C., Lin, J. J., Huang, H. S., Shtil, A. A. & Preobrazhenskaya, M. N., Mar 1 2009, In: Bioorganic and Medicinal Chemistry. 17, 5, p. 1861-1869 9 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Synthesis and evaluation of [ ¹⁸F]Fluorobutyl ethacrynic amide: A potential PET tracer for studying glutathione transferase

  Huang, H. L., Yeh, C. N., Chang, K. W., Chen, J. T., Lin, K. J., Chiang, L. W., Jeng, K. C., Wang, W. T., Lim, K. H., Chen, C. G., Lin, K. I., Huang, Y. C., Lin, W. J., Yen, T. C. & Yu, C. S., Jun 15 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 12, p. 3998-4003 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach

  Wu, Y. S., Coumar, M. S., Chang, J. Y., Sun, H. Y., Kuo, F. M., Kuo, C. C., Chen, Y. J., Chang, C. Y., Hsiao, C. L., Liou, J. P., Chen, C. P., Yao, H. T., Chiang, Y. K., Tan, U. K., Chen, C. T., Chu, C. Y., Wu, S. Y., Yeh, T. K., Lin, C. Y. & Hsieh, H. P., Aug 13 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4941-4945 5 p.

  Research output: Contribution to journal › Article › peer-review
  88 Citations (Scopus)

• Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors

  Huang, W. J., Chen, C. C., Chao, S. W., Yu, C. C., Yang, C. Y., Guh, J. H., Lin, Y. C., Kuo, C. I., Yang, P. & Chang, C. I., Sept 2011, In: European Journal of Medicinal Chemistry. 46, 9, p. 4042-4049 8 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives

  Chin, Y. P., Huang, W. J., Hsu, F-L., Lin, M. H. & Lin, Y. L., Jun 2011, In: Archiv der Pharmazie. 344, 6, p. 386-393 8 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Synthesis and evaluation of antibacterial and anti-oxidant activity of small molecular chitosan–fucoidan conjugate nanoparticles

  Tsai, L. C., Tsai, M. L., Lu, K. Y. & Mi, F. L., Aug 1 2018, In: Research on Chemical Intermediates. 44, 8, p. 4855-4871 17 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Synthesis and Evaluation of Cantharidinimides on Human Cancer Cells

  Tseng, I. J., Sheu, S. Y., Lin, P. Y., Lee, J. A., Ou, K. L. & Lee, L. W., Oct 2012, In: Journal of Experimental and Clinical Medicine. 4, 5, p. 280-283 4 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors This Letter is dedicated to Dr. K. L. Dhar on the occasion of his 78th birthday.

  Singh, H., Sharma, S., Ojha, R., Gupta, M. K., Nepali, K. & Bedi, P. M. S., Sept 1 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 17, p. 4192-4197 6 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Synthesis and evaluation of new 3-substituted-4-chloro-thioxanthone derivatives as potent anti-breast cancer agents

  Chen, C. L., Chen, T. C., Lee, C. C., Shih, L. C., Lin, C. Y., Hsieh, Y. Y., Ali, A. A. A. & Huang, H. S., Dec 2019, In: Arabian Journal of Chemistry. 12, 8

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents

  Liu, Y-M., Chen, C-H., Yeh, T-K. & Liou, J-P., Feb 21 2019, In: Future Medicinal Chemistry.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Synthesis and Evaluation of Terbenzimidazoles as Topoisomerase I Inhibitors

  Sun, Q., Gatto, B., Yu, C., Liu, A., Liu, L. F. & LaVoie, E. J., Sept 1 1995, In: Journal of Medicinal Chemistry. 38, 18, p. 3638-3644 7 p.

  Research output: Contribution to journal › Article › peer-review
  79 Citations (Scopus)

• Synthesis and human telomerase inhibition of a series of regioisomeric disubstituted amidoanthraquinones

  Huang, H. S., Chen, I. B., Huang, K. F., Lu, W. C., Shieh, F. Y., Huang, Y. Y., Huang, F. C. & Lin, J. J., Feb 2007, In: Chemical and Pharmaceutical Bulletin. 55, 2, p. 284-292 9 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• SYNTHESIS AND OPIATE ACTIVITY OF HUMAN β‐ENDORPHIN ANALOGS WITH VARIOUS CHAIN LENGTHS

  Yeung, HW. W., Yamashiro, D., Chang, WC. C. & Li, C. H., Jan 1 1978, In: International Journal of Peptide and Protein Research. 12, 1, p. 42-46 5 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Synthesis and pharmacological evaluation of isoindolo[1,2-b]quinazolinone and isoindolo[2,1-a]benzimidazole derivatives related to the antitumor agent batracylin

  Meegalla, S. K., Stevens, G. J., McQueen, C. A., Chen, A. Y., Yu, C., Liu, L. F., Barrows, L. R. & LaVoie, E. J., 1994, In: Journal of Medicinal Chemistry. 37, 20, p. 3434-3439 6 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Synthesis and reduction of azidodeoxy derivatives of chitin

  Furuhata, K., Arai, N., Ishizuka, S., Tseng, H. & Sakamoto, M., 1998, In: Sen'i Gakkaishi. 54, p. 647-653

  Research output: Contribution to journal › Article › peer-review

  6 Citations (Scopus)

• Synthesis and Ribonucleotide reductase inhibitory activity of thiosemicarbazones

  Krishnan, K., Prathiba, K., Jayaprakash, V., Basu, A., Mishra, N., Zhou, B., Hu, S. & Yen, Y., Dec 1 2008, In: Bioorganic and Medicinal Chemistry Letters. 18, 23, p. 6248-6250 3 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Synthesis and structure-activity correlations of the cytotoxic bifunctional 1,4-diamidoanthraquinone derivatives

  Huang, H. S., Chiu, H. F., Lee, A. L., Guo, C. L. & Yuan, C. L., Dec 1 2004, In: Bioorganic and Medicinal Chemistry. 12, 23, p. 6163-6170 8 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Synthesis and structure-activity relationship of 2-aminobenzophenone derivatives as antimitotic agents

  Liou, J. P., Chang, C. W., Song, J. S., Yang, Y. N., Yeh, C. F., Tseng, H. Y., Lo, Y. K., Chang, Y. L., Chang, C. M. & Hsieh, H. P., Jun 6 2002, In: Journal of Medicinal Chemistry. 45, 12, p. 2556-2562 7 p.

  Research output: Contribution to journal › Article › peer-review
  134 Citations (Scopus)

• Synthesis and structure-activity relationships of 1-benzyl-4,5,6- trimethoxyindoles as a novel class of potent antimitotic agents

  Lai, M-J., Kuo, C-C., Yeh, T-K., Hsieh, H-P., Chen, L-T., Pan, W-Y., Hsu, K. Y., Chang, J-Y. & Liou, J. P., Apr 17 2009, In: ChemMedChem. 4, 4, p. 588-593 6 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Synthesis and structure-activity relationships of 2-amino-1- aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents

  Reddy, G. R., Kuo, C-C., Tan, U-K., Coumar, M. S., Chang, C-Y., Chiang, Y-K., Lai, M-J., Yeh, J-Y., Wu, S-Y., Chang, J-Y., Liou, J. P. & Hsieh, H-P., Dec 25 2008, In: Journal of Medicinal Chemistry. 51, 24, p. 8163-8167 5 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents

  Liou, J. P., Chang, J. Y., Chang, C. W., Chang, C. Y., Mahindroo, N., Kuo, F. M. & Hsieh, H. P., May 20 2004, In: Journal of Medicinal Chemistry. 47, 11, p. 2897-2905 9 p.

  Research output: Contribution to journal › Article › peer-review
  105 Citations (Scopus)

• Synthesised Conductive/Magnetic Composite Particles for Magnetic Ablations of Tumours

  Lee, C. W., Liu, J. F., Wei, W. C., Chiang, M. H., Chen, T. Y., Liao, S. H., Chiang, Y. C., Kuo, W. C., Chen, K. L., Peng, K. T., Liu, Y. B. & Chieh, J. J., Oct 2022, In: Micromachines. 13, 10, 1605.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Synthesis of (±)-Glaucine and (±)-Neospirodienone via an One-Pot Bischler-Napieralski Reaction and Oxidative Coupling by a Hypervalent Iodine Reagent

  Huang, W. J., Singh, O. V., Chen, C. H. & Lee, S. S., 2004, In: Helvetica Chimica Acta. 87, 1, p. 167-174 8 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies

  Singh, J., Sharma, S., Saxena, A. K., Nepali, K. & Bedi, P. M. S., Jul 1 2013, In: Medicinal Chemistry Research. 22, 7, p. 3160-3169 10 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Synthesis of 1,4-dihydro-2-phenyl-4,4-bis(4-pyridinylmethyl)-2H-isoquinolin-3-one and related compounds as acetylcholine release enhancers

  Lin, M. S., Hsin, L. W., Tsai, H. B., Tsai, M. C. & Cheng, C. Y., Aug 2002, In: Chinese Pharmaceutical Journal. 54, 4, p. 271-281 11 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)