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  Crystal structure of D-aminoacylase from Alcaligenes faecalis DA1: A novel subset of amidohydrolases and insights into the enzyme mechanism

  Liaw, S. H., Chen, S. J., Ko, T. P., Hsu, C. S., Chen, C. J., Wang, A. H. J. & Tsai, Y. C., Feb 14 2003, In: Journal of Biological Chemistry. 278, 7, p. 4957-4962 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  58 Citations (Scopus)

• Crystal structure of DFA0005 complexed with α-ketoglutarate: A novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus

  Liao, C. J., Chin, K. H., Lin, C. H., Tsai, P. S. F., Lyu, P. C., Young, C. C., Wang, A. H. J. & Chou, S. H., Nov 1 2008, In: Proteins: Structure, Function and Genetics. 73, 2, p. 362-371 10 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in staphylococcus epidermidis

  Jeng, W. Y., Ko, T. P., Liu, C-I., Guo, R. T., Liu, C. L., Shr, H. L. & Wang, A. H. J., Mar 2008, In: Nucleic Acids Research. 36, 5, p. 1567-1577 11 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6 Å resolution: Implications in virion assembly and immunogenicity

  Lee, C. C., Ko, T. P., Chou, C. C., Yoshimura, M., Doong, S. R., Wang, M. Y. & Wang, A. H. J., Jul 2006, In: Journal of Structural Biology. 155, 1, p. 74-86 13 p.

  Research output: Contribution to journal › Article › peer-review
  58 Citations (Scopus)

• Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination

  Guo, R. T., Kuo, C. J., Chou, C. C., Ko, T. P., Shr, H. L., Liang, P. H. & Wang, A. H. J., Feb 6 2004, In: Journal of Biological Chemistry. 279, 6, p. 4903-4912 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  64 Citations (Scopus)

• Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis

  Lee, C. C., Ko, T. P., Chen, C. T., Chan, Y. T., Lo, S. Y., Chang, J. Y., Chen, Y. W., Chung, T. F., Hsieh, H. J., Hsiao, C. D. & Wang, A. H. J., Jan 18 2019, In: ChemBioChem. 20, 2, p. 193-202 10 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Crystal structure of RecX: A potent regulatory protein of RecA from Xanthomonas campestris

  Yang, C. Y., Chin, K. H., Yang, M. T., Wang, A. H. J. & Chou, S. H., Feb 1 2009, In: Proteins: Structure, Function and Bioinformatics. 74, 2, p. 530-537 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix α7 in Phosphatase Activity

  Singh, J. P., Lin, M. J., Hsu, S. F., Peti, W., Lee, C. C. & Meng, T. C., Dec 28 2021, In: Biochemistry. 60, 51

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Crystal structure of the [Mg^2+-(chromomycin A_{3 2}]-d(TTGGCCAA)₂ complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion

  Hou, M. H., Robinson, H., Gao, Y. G. & Wang, A. H. J., 2004, In: Nucleic Acids Research. 32, 7, p. 2214-2222 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  72 Citations (Scopus)

• Crystal Structure of the C-Terminal Domain of a Flagellar Hook-Capping Protein from Xanthomonas campestris

  Kuo, W. T., Chin, K. H., Lo, W. T., Wang, A. H. J. & Chou, S. H., Aug 1 2008, In: Journal of Molecular Biology. 381, 1, p. 189-199 11 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Crystal structure of the hyperthermophilic archaeal DNA-binding protein Sso10b2 at a resolution of 1.85 Angstroms

  Chou, C. C., Lin, T. W., Chen, C. Y. & Wang, A. H. J., Jul 2003, In: Journal of Bacteriology. 185, 14, p. 4066-4073 8 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Crystal structure of the left-handed archaeal RadA helical filament: Identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins

  Chen, L. T., Ko, T. P., Chang, Y. C., Lin, K. A., Chang, C. S., Wang, A. H. J. & Wang, T. F., Mar 2007, In: Nucleic Acids Research. 35, 6, p. 1787-1801 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  35 Citations (Scopus)

• Crystal structure of the N-terminal domain of TagH reveals a potential drug targeting site

  Yang, C. S., Huang, W. C., Ko, T. P., Wang, Y. C., Wang, A. H. J. & Chen, Y., Jan 15 2021, In: Biochemical and Biophysical Research Communications. 536, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination

  Chang, T. H., Guo, R. T., Ko, T. P., Wang, A. H. J. & Liang, P. H., May 26 2006, In: Journal of Biological Chemistry. 281, 21, p. 14991-15000 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  82 Citations (Scopus)

• Crystal Structure of Vaccinia Viral A27 Protein Reveals a Novel Structure Critical for Its Function and Complex Formation with A26 Protein

  Chang, T. H., Chang, S. J., Hsieh, F. L., Ko, T. P., Lin, C. T., Ho, M. R., Wang, I., Hsu, S. T. D., Guo, R. T., Chang, W. & Wang, A. H. J., Aug 2013, In: PLoS Pathogens. 9, 8, e1003563.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Citations (Scopus)

• Crystal structure of vespid phospholipase A₁ reveals insights into the mechanism for cause of membrane dysfunction

  Hou, M. H., Chuang, C. Y., Ko, T. P., Hu, N. J., Chou, C. C., Shih, Y. P., Ho, C. L. & Wang, A. H. J., Jan 1 2016, In: Insect Biochemistry and Molecular Biology. 68, p. 79-88 10 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Crystal structure of XC5357 from Xanthomonas campestris: A putative tetracenomycin polyketide synthesis protein adopting a novel cupin subfamily structure

  Chin, K. H., Chou, C. C., Wang, A. H. J. & Chou, S. H., Dec 1 2006, In: Proteins: Structure, Function and Genetics. 65, 4, p. 1046-1050 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Crystal structure of yeast cytosine deaminase: Insights into enzyme mechanism and evolution

  Ko, T. P., Lin, J. J., Hu, C. Y., Hsu, Y. H., Wang, A. H. J. & Liaw, S. H., May 23 2003, In: Journal of Biological Chemistry. 278, 21, p. 19111-19117 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  99 Citations (Scopus)

• Crystal structure of Z-DNA without an alternating purine-pyrimidine sequence

  Wang, A. H. J., Gessner, R. V., van Der Marel, G. A., van Boom, J. H. & Rich, A., 1985, In: Proceedings of the National Academy of Sciences of the United States of America. 82, 11, p. 3611-3615 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  91 Citations (Scopus)

• Crystal structures of complexes of the branched-chain aminotransferase from deinococcus radiodurans with α-Ketoisocaproate and _L-glutamate suggest the radiation resistance of this enzyme for catalysis

  Chen, C. D., Lin, C. H., Chuankhayan, P., Huang, Y. C., Hsieh, Y. C., Huang, T. F., Guan, H. H., Liu, M. Y., Chang, W. C. & Chena, C. J., Nov 1 2012, In: Journal of Bacteriology. 194, 22, p. 6206-6216 11 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Crystal structures of four a-DNA decamers that contain C5-propyne- cytosines

  Gao, Y. G. & Wang, A. H. J., 1998, In: Nucleosides and Nucleotides. 17, 9-11, p. 2093-2102 10 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Crystal structures of four morpholino-doxorubicin anticancer drugs complexed with d(Cgtacg) and d(cgatcg): Implications in drug-dna crosslink

  Gao, Y. G. & Wang, A. H., Aug 1995, In: Journal of Biomolecular Structure and Dynamics. 13, 1, p. 103-117 15 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation

  Huang, K. F., Liu, Y. L., Cheng, W. J., Ko, T. P. & Wang, A. H. J., Sep 13 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13117-13122 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  85 Citations (Scopus)

• Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms

  Han, X., Chen, C. C., Kuo, C. J., Huang, C. H., Zheng, Y., Ko, T. P., Zhu, Z., Feng, X., Wang, K., Oldfield, E., Wang, A. H. J., Liang, P. H., Guo, R. T. & Ma, Y., Jan 2015, In: Proteins: Structure, Function and Bioinformatics. 83, 1, p. 37-45 9 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: Insights into transcriptional regulation of the bla and mec operons

  Safo, M. K., Zhao, Q., Ko, T. P., Musayev, F. N., Robinson, H., Scarsdale, N., Wang, A. H. J. & Archer, G. L., Mar 2005, In: Journal of Bacteriology. 187, 5, p. 1833-1844 12 p.

  Research output: Contribution to journal › Article › peer-review
  55 Citations (Scopus)

• Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs

  Su, S., Gao, Y. G., Robinson, H., Liaw, Y. C., Edmondson, S. P., Shriver, J. W. & Wang, A. H. J., Oct 27 2000, In: Journal of Molecular Biology. 303, 3, p. 395-403 9 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris

  Jeng, W. Y., Liu, C. I., Lu, T. J., Lin, H. J., Wang, N. C. & Wang, A. H. J., Jan 18 2019, In: ChemBioChem. 20, 2, p. 295-307 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Crystal structures of the human SUMO-2 protein at 1.6 Å and 1.2 Å resolution: Implication on the functional differences of SUMO proteins

  Huang, W. C., Ko, T. P., Li, S. S. L. & Wang, A. H. J., Oct 2004, In: European Journal of Biochemistry. 271, 20, p. 4114-4122 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  57 Citations (Scopus)

• Crystal structures of the laminarinase catalytic domain from Thermotoga maritima MSB8 in complex with inhibitors: Essential residues for β-1,3- and β-1,4-glucan selection

  Jeng, W. Y., Wang, N. C., Lin, C. T., Shyur, L. F. & Wang, A. H. J., Dec 30 2011, In: Journal of Biological Chemistry. 286, 52, p. 45030-45040 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  27 Citations (Scopus)

• Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: Roles of the metal ion and conserved residues in catalysis

  Guo, R. T., Ko, T. P., Chen, A. P. C., Kuo, C. J., Wang, A. H. J. & Liang, P. H., May 27 2005, In: Journal of Biological Chemistry. 280, 21, p. 20762-20774 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  100 Citations (Scopus)

• Crystal Structures of Y41H and Y41F Mutants of Gene V Protein from Ff Phage Suggest Possible Protein-Protein Interactions in the GVP-ssDNA Complex

  Guan, Y., Zhang, H., Wang, A. H. J., Konings, R. N. H., Hilbers, C. W. & Terwilliger, T. C., Jun 1 1994, In: Biochemistry. 33, 25, p. 7768-7778 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

  Liao, C. F., Lin, S. H., Chen, H. C., Tai, C. J., Chang, C. C., Li, L. T., Yeh, C. M., Yeh, K. T., Chen, Y. C., Hsu, T. H., Shen, S. C., Lee, W. R., Chiou, J. F., Luo, S. F. & Jiang, M. C., 2012, In: Molecular Medicine. 18, 9, p. 1269-1280 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  44 Citations (Scopus)

• CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

  Lee, W. R., Shen, S. C., Wu, P. R., Chou, C. L., Shih, Y. H., Yeh, C. M., Yeh, K. T. & Jiang, M. C., Nov 2016, In: Molecular Carcinogenesis.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• CSE1L modulates ras-induced cancer cell invasion: Correlation of K-ras mutation and CSE1L expression in colorectal cancer progression

  Jiang, M. C., Yeh, C. M., Tai, C. J., Chen, H. C., Lin, S. H., Su, T. C., Shen, S. C., Lee, W. R., Liao, C. F., Li, L. T., Lee, C. H., Chen, Y. C., Yeh, K. T. & Chang, C. C., Sep 2013, In: American Journal of Surgery. 206, 3, p. 418-427 10 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• c-Src/Jak2/PDGFR/PKCδ-dependent MMP-9 induction is required for thrombin-stimulated rat brain astrocytes migration

  Lin, C. C., Lee, I-T., Chi, P. L., Hsieh, H. L., Cheng, S. E., Hsiao, L. D., Liu, C. J. & Yang, C. M., Jan 1 2014, In: Molecular Neurobiology. 49, 2, p. 658-672 15 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• C-Src-dependent MAPKs/AP-1 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells

  Yang, C. M., Lee, I-T., Lin, C. C., Wang, C. H., Cherng, W. J. & Hsiao, L. D., Apr 15 2013, In: Biochemical Pharmacology. 85, 8, p. 1115-1123 9 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• c-Src-dependent transactivation of EGFR mediates CORM-2-induced HO-1 expression in human tracheal smooth muscle cells

  Yang, C. M., Lin, C. C., Lee, I-T., Hsu, C. K., Tai, Y. C., Hsieh, H. L., Chi, P. L. & Hsiao, L. D., Oct 1 2015, In: Journal of Cellular Physiology. 230, 10, p. 2351-2361 11 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• C-Src-dependent transactivation of PDGFR contributes to TNF-α-induced MMP-9 expression and functional impairment in osteoblasts

  Tsai, C. L., Chen, W. C., Lee, I-T., Chi, P. L., Cheng, S. E. & Yang, C. M., Mar 1 2014, In: Bone. 60, p. 186-197 12 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• c-Src mediates thrombin-induced NF-κB activation and IL-8/CXCL8 expression in lung epithelial cells

  Lin, C. H., Cheng, D. H-W., Hsu, M-J., Chen, M-C., Lin, C. C. & Chen, B-C., Sep 1 2006, In: Journal of Immunology. 177, 5, p. 3427-3438 12 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• CTA095, a Novel Etk and Src Dual Inhibitor, Induces Apoptosis in Prostate Cancer Cells and Overcomes Resistance to Src Inhibitors

  Guo, W., Liu, R., Bhardwaj, G., Ma, A. H., Changou, C., Yang, J. C., Li, Y., Feng, C., Luo, Y., Mazloom, A., Sanchez, E., Wang, Y., Huang, W., Patterson, R., Evans, C. P., Lam, K. S. & Kung, H. J., Aug 15 2013, In: PLoS One. 8, 8, e70910.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• CT and MRI findings correlate with the time-course of unresectable cavernous haemangioma of the liver after fractionated radiotherapy

  Lee, H. L., Chung, T. S., Chen, S. W. & Lao, W. T., Mar 1 2012, In: British Journal of Radiology. 85, 1011, p. e49-e52

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• CT angiographic diagnosis of a ruptured intraventricular arteriovenous malformation in a teenager playing a video game

  Chen, Y. L., Kao, H. W., Juan, C. J., Hsueh, C. J., Huang, G. S., Lo, H. C. & Chen, C. Y., Oct 2011, In: Neuroradiology Journal. 24, 5, p. 762-766 5 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• CT angiography findings predictive of kidney injury in chronic aortic dissection

  Kuo, T. T., Chen, P. L., Huang, C. Y., Chen, I. M. & Shih, C. C., Jun 2020, In: American Journal of Roentgenology. 214, 6, p. 1409-1416 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• CT attenuation features of individual calcified coronary plaque: differences among asymptomatic, stable angina pectoris, and acute coronary syndrome groups

  Huang, Y-L., Lin, H-S., Wu, C. C., Wu, F-Z., Yeh, C., Chiou, K-R., Mar, G-Y. & Wu, M-T., 2015, In: PLoS One. 10, 6, p. e0131254

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• CT diagnosis of small bowel obstruction due to phytobezoar

  Liou, C. H., Yu, C. Y., Lin, C. C., Chao, Y. C., Liou, Y. C., Juan, C. J. & Chen, C. Y., Sep 2003, In: Journal of the Formosan Medical Association = Taiwan yi zhi. 102, 9, p. 620-624 5 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• C-terminal region of dengue virus nonstructural protein 1 is involved in endothelial cell cross-reactivity via molecular mimicry

  Wan, S. W., Lin, C. F., Chen, M. C., Lei, H. Y., Liu, H. S., Yeh, T. M., Liu, C. C. & Lin, Y. S., 2008, In: American Journal of Infectious Diseases. 4, 1, p. 85-91 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• C-terminus of Hsc70-interacting protein (CHIP) enhances stemness properties of human Wharton’s jelly mesenchymal stem cell

  Yang, C. K., Feng, C. C., Lo, J. F., Chen, J. W., Padma, V. V., Lai, C. H., Chen, T. S., Chen, R. J., Liao, P. H. & Huang, C. Y., Nov 17 2018, In: Biotechnic and Histochemistry. 93, 8, p. 632-639 8 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• CT features of genitourinary tuberculosis

  Wang, L. J., Wong, Y. C., Chen, C. J. & Lim, K. E., 1997, In: Journal of Computer Assisted Tomography. 21, 2, p. 254-258 5 p.

  Research output: Contribution to journal › Article › peer-review
  63 Citations (Scopus)

• CT finding of renal vein invasion by aggressive renal angiomyolipoma: A case report

  Lin, I. C., Chen, C. J., Lin, C. H. & Hwang, J. C., Oct 2006, In: Chinese Journal of Radiology. 31, 5, p. 261-265 5 p.

  Research output: Contribution to journal › Article › peer-review

• CT findings of pulmonary cryptococcosis: A series of 12 cases

  Lee, W. Y., Wu, J. T., Jeng, C. M., Hsu, C. Y., Jung-Sen-Liu, Wang, Y. C., Wu, C. Y., Chang, H. Y., Huang, J. C., Yang, C. M. & Kung, C. H., Dec 1 2005, In: Chinese Journal of Radiology. 30, 6, p. 319-325 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)