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  Tamoxifen use reduces the risk of osteoporotic fractures in women with breast cancer in Asia: A nationwide population-based cohort study

  Tzeng, H. E., Muo, C. H., Chen, H. T., Hwang, W. L., Hsu, H. C. & Tsai, C. H., May 20 2015, In: BMC Musculoskeletal Disorders. 16, 1, 123.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Tandem-cycle high-dose melphalan and cisplatin with peripheral blood progenitor cell support in patients with breast cancer and other malignancies

  Somlo, G., Chow, W., Hamasaki, V., Leong, L., Margolin, K., Morgan, R., Sniecinski, I., Frankel, P., Reardon, D., Longmate, J., Raschko, J., Shibata, S., O'Donnell, M., Smith, E., Tetef, M., Forman, S., Yen, Y., Molina, A. & Doroshow, J. H., 2001, In: Biology of Blood and Marrow Transplantation. 7, 5, p. 284-293 10 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region

  Hung, W. Y., Lin, J. C., Lee, L. M., Wu, C. W., Tseng, L. M., Yin, P. H., Chi, C. W. & Lee, H. C., Mar 2008, In: Mutagenesis. 23, 2, p. 137-142 6 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Tandemly duplicated α globin genes of gibbon

  Bailey, A. D., Stanhope, M., Slightom, J. L., Goodman, M., Shen, C. C. & Shen, C. C., 1992, In: Journal of Biological Chemistry. 267, 26, p. 18398-18406 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Tandem mach zehnder directional coupler design and simulation on silicon platform for optical coherence tomography applications

  Lu, Y. T., Widhianto, B. Y. B., Hsu, S. H. & Chang, C. C., Feb 2 2020, In: Sensors (Switzerland). 20, 4, 1054.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Tannic acid, a vasodilator present in wines and beverages, stimulates Ca²⁺ influx via TRP channels in bEND.3 endothelial cells

  Tsai, T. Y., Leong, I. L., Shiao, L. R., Wong, K. L., Shao, L., Chan, P. & Leung, Y. M., May 21 2020, In: Biochemical and Biophysical Research Communications. 526, 1, p. 117-121 5 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Tannic acid suppresses ultraviolet B-induced inflammatory signaling and complement factor B on human retinal pigment epithelial cells

  Chou, W. W., Wang, Y. S., Chen, K. C., Wu, J. M., Liang, C. L. & Juo, S. H. H., 2012, In: Cellular Immunology. 273, 1, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Tannins, flavonol sulfonates, and a norlignan from Phyllanthus virgatus

  Huang, Y. L., Chen, C. C., Hsu, F. L. & Chen, C. F., Oct 1998, In: Journal of Natural Products. 61, 10, p. 1194-1197 4 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• Tannins and Related Compounds from Quisqualis indica

  Lin, T. C., Ma, Y. T., Wu, J. & Hsu, F-L., 1997, In: Journal of the Chinese Chemical Society. 44, 2, p. 151-155 5 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Tannins from Albizia lebbek

  Ma, Y. T., Hsiao, S. C., Chen, H. F. & Hsu, F. L., Dec 1997, In: Phytochemistry. 46, 8, p. 1451-1452 2 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Tannins from Betel Nuts

  Ma, Y. T., Hsu, F-L., Lan, S. J. J. & Chen, C. F., 1996, In: Journal of the Chinese Chemical Society. 43, 1, p. 77-81 5 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes

  Hong, H. J., Liu, J. C., Cheng, T-H. & Chan, P., Dec 2010, In: Acta Pharmacologica Sinica. 31, 12, p. 1569-1575 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Citations (Scopus)

• Tanshinone IIA attenuates cyclic strain-induced endothelin-1 expression in human umbilical vein endothelial cells

  Hong, H. J., Hsu, F. L., Tsai, S. C., Lin, C. H., Liu, J. C., Chen, J. J., Cheng, T. H. & Chan, P., Jan 2012, In: Clinical and Experimental Pharmacology and Physiology. 39, 1, p. 63-68 6 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Tanshinone IIA attenuates H₂O₂-induced injury in human umbilical vein endothelial cells

  Chan, P., Chen, Y. C., Lin, L. J., Cheng, T-H., Anzai, K., Chen, Y. H., Liu, Z. M., Lin, J. G. & Hong, H. J., 2012, In: American Journal of Chinese Medicine. 40, 6, p. 1307-1319 13 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells

  Chen, T. H., Hsu, Y. T., Chen, C. H., Kao, S. H. & Lee, H. M., Feb 2007, In: Mitochondrion. 7, 1-2, p. 101-105 5 p.

  Research output: Contribution to journal › Article › peer-review
  58 Citations (Scopus)

• Tanshinone IIA Induces Heme Oxygenase 1 Expression and Inhibits Cyclic Strain-Induced Interleukin 8 Expression in Vascular Endothelial Cells

  Zhuang, S., Cheng, T-H., Shih, N. L., Liu, J. C., Chen, J. J., Hong, H. J. & Chan, P., Apr 1 2016, In: American Journal of Chinese Medicine. 44, 2, p. 377-388 12 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts

  Chan, P., Liu, J. C., Lin, L. J., Chen, P. Y., Cheng, T-H., Lin, J. G. & Hong, H. J., 2011, In: American Journal of Chinese Medicine. 39, 2, p. 381-394 14 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Tanshinone IIA inhibits β-catenin nuclear translocation and IGF-2R activation via estrogen receptors to suppress angiotensin II-induced H9c2 cardiomyoblast cell apoptosis

  Chen, Y. F., Day, C. H., Lee, N. H., Chen, Y. F., Yang, J. J., Lin, C. H., Chen, R. J., Rajendran, P., Viswanadha, V. P. & Huang, C. Y., Sep 30 2017, In: International Journal of Medical Sciences. 14, 12, p. 1284-1291 8 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Tanshinone IIA prevents doxorubicin-induced cardiomyocyte apoptosis through Akt-dependent pathway

  Hong, H. J., Liu, J. C., Chen, P. Y., Chen, J. J., Chan, P. & Cheng, T-H., May 31 2012, In: International Journal of Cardiology. 157, 2, p. 174-179 6 p.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)

• Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

  Chen, Y. F., Lee, N. H., Pai, P. Y., Chung, L. C., Shen, C. Y., Rajendran, P., Chen, Y. F., Chen, R. J., Padma Viswanadha, V., Kuo, W. W. & Huang, C. Y., Sep 3 2017, In: Journal of Receptors and Signal Transduction. 37, 5, p. 493-499 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

  Lai, H-H., Li, C-W., Hong, C-C., Sun, H-Y., Chiu, C-F., Ou, D-L. & Chen, P-S., Apr 2019, In: Molecular Oncology. 13, 4, p. 928-945 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (Scopus)

• Tarbp2 suppresses ubiquitin-proteasomal degradation of hif-1α in breast cancer

  Li, J. N., Chen, P. S., Chiu, C. F., Lyu, Y. J., Lo, C., Tsai, L. W. & Wang, M. Y., Jan 1 2022, In: International journal of molecular sciences. 23, 1, 208.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• TARC/CCL17 gene polymorphisms and expression associated with susceptibility and coronary artery aneurysm formation in Kawasaki disease

  Lee, C. P., Huang, Y. H., Hsu, Y. W., Yang, K. D., Chien, S-C., Yu, H. R., Yang, Y. L., Wang, C. L., Chang, W. C. & Kuo, H. C., Nov 2013, In: Pediatric Research. 74, 5, p. 545-551 7 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity

  Tan, S. J., Lee, L. J., Tzeng, C. R., Wang, C-W., Hsu, M. I. & Chen, C. H., Nov 1 2014, In: Reproductive BioMedicine Online. 29, 5, p. 612-620 9 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Targeted Casp8AP2 methylation increases drug resistance in mesenchymal stem cells and cancer cells

  Lee, K. D., Pai, M. Y., Hsu, C. C., Chen, C. C., Chen, Y. L., Chu, P. Y., Lee, C. H., Chen, L. T., Chang, J. Y., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Jun 15 2012, In: Biochemical and Biophysical Research Communications. 422, 4, p. 578-585 8 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Targeted concurrent and sequential delivery of chemotherapeutic and antiangiogenic agents to the brain by using drug-loaded nanofibrous membranes

  Tseng, Y. Y., Yang, T. C., Wang, Y. C., Lee, W. H., Chang, T. M., Kau, Y. C. & Liu, S. J., Feb 14 2017, In: International Journal of Nanomedicine. 12, p. 1265-1276 12 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac

  Sudha, T., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H. Y., Davis, P. J. & Mousa, S. A., Feb 1 2017, In: Nanomedicine. 12, 3, p. 195-205 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac

  Sudha, T., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H. Y., Davis, P. J. & Mousa, S. A., Feb 15 2017, In: International Journal of Nanomedicine. 12, p. 1305-1315 11 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Targeted delivery system for juxtacrine signaling growth factor based on rhBMP-2-mediated carrier-protein conjugation

  Liu, H. W., Chen, C. H., Tsai, C. L. & Hsiue, G. H., Oct 2006, In: Bone. 39, 4, p. 825-836 12 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice

  Wu, L. S., Cheng, W. C. & Shen, C. K. J., Aug 10 2012, In: Journal of Biological Chemistry. 287, 33, p. 27335-27344 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  111 Citations (Scopus)

• Targeted Disruption in Mice of a Neural Stem Cell-Maintaining, KRAB-Zn Finger-Encoding Gene That Has Rapidly Evolved in the Human Lineage

  Chien, H. C., Wang, H. Y., Su, Y. N., Lai, K. Y., Lu, L. C., Chen, P. C., Tsai, S. F., Wu, C. I., Hsieh, W. S. & Shen, C. K. J., Oct 10 2012, In: PLoS ONE. 7, 10, e47481.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Citations (Scopus)

• Targeted disruption of nebulette protein expression alters cardiac myofibril assembly and function

  Moncman, C. L. & Wang, K., 2002, In: Experimental Cell Research. 273, 2, p. 204-218 15 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Targeted gene delivery to alveolar macrophages via Fc receptor-mediated endocytosis

  Rojanasakul, Y., Wang, L. Y., Malanga, C. J., Ma, J. K. H. & Liaw, J., 1994, In: Pharmaceutical Research. 11, 12, p. 1731-1736 6 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Targeted mass CPR training for families of cardiac patients - Experience in Taipei city

  Cheng, Y. C., Hu, S. C., Yen, D., Kao, W. F. & Lee, C. H., 1997, In: Tzu Chi Medical Journal. 9, 4, p. 273-278 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Targeted methylation of CMV and E1A viral promoters

  Hsu, C. C., Li, H. P., Hung, Y. H., Leu, Y. W., Wu, W. H., Wang, F. S., Lee, K. D., Chang, P. J., Wu, C. S., Lu, Y. J., Huang, T. H. M., Chang, Y. S. & Hsiao, S. H., Nov 12 2010, In: Biochemical and Biophysical Research Communications. 402, 2, p. 228-234 7 p.

  Research output: Contribution to journal › Article › peer-review
  55 Citations (Scopus)

• Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells

  Teng, I. W., Hou, P. C., Lee, K. D., Chu, P. Y., Yeh, K. T., Jin, V. X., Tseng, M. J., Tsai, S. J., Chang, Y. S., Wu, C. S., Sun, H. S., Tsai, K. D., Jeng, L. B., Nephew, K. P., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Jul 1 2011, In: Cancer Research. 71, 13, p. 4653-4663 11 p.

  Research output: Contribution to journal › Article › peer-review
  84 Citations (Scopus)

• Targeted PARP Inhibition Combined with FGFR1 Blockade is Synthetically Lethal to Malignant Cells in Patients with Pancreatic Cancer

  Lai, S. W., Bamodu, O. A., Chen, J. H., Wu, A. T., Lee, W. H., Chao, T. Y. & Yeh, C. T., Apr 8 2020, In: Cells. 9, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Targeted treatment of primary aldosteronism – The consensus of Taiwan Society of Aldosteronism

  TAIPAI, Taiwan Primary Aldosteronism Investigator, Jan 2019, In: Journal of the Formosan Medical Association. 118, 1P1, p. 72-82 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma

  Chen, C. Y., Lin, Y-S., Chen, C. L., Chao, P. Z., Chiou, J. F., Kuo, C. C., Lee, F. P., Lin, Y. F., Sung, Y. H., Lin, Y. T., Li, C. F., Chen, Y. J. & Chen, C. H., 2015, In: Oncotarget. 6, 29, p. 26946-26959 14 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Targeting Autophagy Augments BBR-Mediated Cell Death in Human Hepatoma Cells Harboring Hepatitis C Virus RNA

  Tai, C. J., Jassey, A., Liu, C. H., Tai, C. J., Richardson, C. D., Wong, S. H. & Lin, L. T., Apr 8 2020, In: Cells. 9, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)

• Targeting autophagy by MPT0L145, a highly potent pik3c3 inhibitor, provides synergistic interaction to targeted or chemotherapeutic agents in cancer cells

  Chen, C. H., Hsieh, T. H., Lin, Y. C., Liu, Y. R., Liou, J. P. & Yen, Y., Sep 2019, In: Cancers. 11, 9, 1345.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model

  Nguyen, H. G., Yang, J. C., Kung, H. J., Shi, X. B., Tilki, D., Lara, P. N., Devere White, R. W., Gao, A. C. & Evans, C. P., Sep 4 2014, In: Oncogene. 33, 36, p. 4521-4530 10 p.

  Research output: Contribution to journal › Article › peer-review
  130 Citations (Scopus)

• Targeting BC200/miR218-5p Signaling Axis for Overcoming Temozolomide Resistance and Suppressing Glioma Stemness

  Su, Y. K., Lin, J. W., Shih, J. W., Chuang, H. Y., Fong, I. H., Yeh, C-T. & Lin, C-M., Aug 8 2020, In: Cells. 9, 8

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Citations (Scopus)

• Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor

  Guo, W., Liu, R., Bhardwaj, G., Yang, J. C., Changou, C., Ma, A. H., Mazloom, A., Chintapalli, S., Xiao, K., Xiao, W., Kumaresan, P., Sanchez, E., Yeh, C. T., Evans, C. P., Patterson, R., Lam, K. S. & Kung, H. J., Jan 1 2014, In: Cell Death and Disease. 5, 9, e1409.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Targeting cancer stem cells in breast cancer: Potential anticancer properties of 6-shogaol and pterostilbene

  Wu, C. H., Hong, B. H., Ho, C. T. & Yen, G. C., 2015, In: Journal of Agricultural and Food Chemistry. 63, 9, p. 2432-2441 10 p.

  Research output: Contribution to journal › Article › peer-review
  61 Citations (Scopus)

• Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers

  Chi, J. Y., Hsiao, Y. W., Li, C. F., Lo, Y. C., Lin, Z. Y., Hong, J. Y., Liu, Y. M., Han, X., Wang, S. M., Chen, B. K., Tsai, K-C. & Wang, J. M., 2015, In: Oncotarget. 6, 27, p. 23987-24001 15 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Targeting c-Myc as a novel approach for hepatocellular carcinoma

  Lin, C. P., Liu, C. R., Lee, C. N., Chan, T. S. & Liu, H. E., 2010, In: World Journal of Hepatology. 2, 1, p. 16-20 5 p.

  Research output: Contribution to journal › Article › peer-review
  96 Citations (Scopus)

• Targeting constitutively activated β1 integrins inhibits prostate cancer metastasis

  Lee, Y. C., Jin, J. K., Cheng, C. J., Huang, C. F., Song, J. H., Huang, M., Brown, W. S., Zhang, S., Yu-Lee, L. Y., Yeh, E. T., McIntyre, B. W., Logothetis, C. J., Gallick, G. E. & Lin, S. H., Apr 2013, In: Molecular Cancer Research. 11, 4, p. 405-417 13 p.

  Research output: Contribution to journal › Article › peer-review
  67 Citations (Scopus)

• Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis

  Tung, M. C., Lin, Y. W., Lee, W. J., Wen, Y. C., Liu, Y. C., Chen, J. Q., Hsiao, M., Yang, Y. C. & Chien, M. H., Apr 2022, In: Cell Death and Disease. 13, 4, 400.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model

  Bisanz, K., Yu, J., Edlund, M., Spohn, B., Hung, M. C., Chung, L. W. K. & Hsieh, C. L., Oct 2005, In: Molecular Therapy. 12, 4, p. 634-643 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  74 Citations (Scopus)