Find Research outputs

Search results

• Disease-modifying Effects of Glucosamine on Interleukin-1β-treated Chondrosarcoma Cells (SW1353) Under Normoxic and Hypoxic Conditions

  Chen, T-L., Sheu, M-T., Liang, Y-C., Lin, Y. J., Hsieh, M-S. & Chen, C-H., Feb 2010, In: Journal of Experimental and Clinical Medicine(Taiwan). 2, 1, p. 17-28 12 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Disease-modifying effects of glucosamine HCl involving regulation of metalloproteinases and chemokines activated by interleukin-1β in human primary synovial fibroblasts

  Lu, H-T., Liang, Y. C., Sheu, M. T., Ho, H. O., Lin, Y. T., Hsieh, M-S. & Chen, C. H., May 1 2008, In: Journal of Cellular Biochemistry. 104, 1, p. 38-50 13 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Disease-inducible transgene expression from a recombinant adeno- associated virus vector in a rat arthritis model

  Pan, R. Y., Xiao, X., Chen, S. L., Li, J., Lin, L. C., Wang, H. J. & Tsao, Y. P., Apr 1999, In: Journal of Virology. 73, 4, p. 3410-3417 8 p.

  Research output: Contribution to journal › Article › peer-review
  97 Citations (Scopus)

• Disease-free survival assessment by artificial neural networks for hepatocellular carcinoma patients after radiofrequency ablation

  Wu, C. F., Wu, Y. J., Liang, P. C., Wu, C. H., Peng, S. F. & Chiu, H. W., Oct 2017, In: Journal of the Formosan Medical Association. 116, 10, p. 765-773 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Disease and economic burden for rare diseases in Taiwan: A longitudinal study using Taiwan’s National Health Insurance Research Database

  Hsu, J. C., Wu, H. C., Feng, W. C., Chou, C. H., Lai, E. C. C. & Lu, C. Y., Sep 2018, In: PLoS ONE. 13, 9, e0204206.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• Discriminative features fusion with bert for social sentiment analysis

  Nguyen, D. D. L., Huang, Y. C. & Chang, Y. C., 2020, Trends in Artificial Intelligence Theory and Applications. Artificial Intelligence Practices - 33rd International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems, IEA/AIE 2020, Proceedings. Fujita, H., Sasaki, J., Fournier-Viger, P. & Ali, M. (eds.). Springer Science and Business Media Deutschland GmbH, p. 30-35 6 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12144 LNAI).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Discrimination of vascular aging using the arterial pulse spectrum and machine-learning analysis

  Hsiu, H., Liu, J. C., Yang, C. J., Chen, H. S., Wu, M. S., Hao, W. R., Lee, K. Y., Hu, C. J., Wang, Y. H. & Fang, Y. A., Jan 2022, In: Microvascular Research. 139, 104240.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Discrimination of Methicillin-Resistant Staphylococcus aureus by MALDI-TOF Mass Spectrometry with Machine Learning Techniques in Patients with Staphylococcus aureus Bacteremia

  Kong, P. H., Chiang, C. H., Lin, T. C., Kuo, S. C., Li, C. F., Hsiung, C. A., Shiue, Y. L., Chiou, H. Y., Wu, L. C. & Tsou, H. H., May 2022, In: Pathogens. 11, 5, 586.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Discrimination of bladder disorders in female lower urinary tract symptoms on ultrasonographic cystourethrography

  Yang, J. M. & Huang, W. C., Nov 1 2002, In: Journal of Ultrasound in Medicine. 21, 11, p. 1249-1255 7 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Discrimination and calibration are concurrently required for model comparison

  Chiu, J. S., Yu, F. C. & Li, Y. C., Sep 20 2006, In: International Journal of Cardiology. 112, 2, p. 245-246 2 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Discrepant MR spectroscopic and perfusion imaging results in a case of malignant transformation of cerebral glioma

  Wu, W. C., Chen, C. Y., Chung, H. W., Juan, C. J., Hsueh, C. J. & Gao, H. W., Nov 2002, In: American Journal of Neuroradiology. 23, 10, p. 1775-1778 4 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Discrepant electrophysiological characteristics and calcium homeostasis of left atrial anterior and posterior myocytes

  Suenari, K., Chen, Y. C., Kao, Y. H., Cheng, C. C., Lin, Y. K., Chen, Y. J. & Chen, S. A., Jan 2011, In: Basic Research in Cardiology. 106, 1, p. 65-74 10 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes

  Lu, Y. Y., Cheng, C. C., Tsai, C. F., Lin, Y. K., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jun 1 2017, In: Clinical Science. 131, 12, p. 1317-1327 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: Subgroup analysis of a double-blind, randomized study

  Lin, Y-S., Lin, L. C., Lin, S. W. & Chang, C. P., 2010, In: Nutrition and Cancer. 62, 5, p. 682-691 10 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Discovery of virulence factors of pathogenic bacteria

  Wu, H. J., Wang, A. H. J. & Jennings, M. P., Feb 2008, In: Current Opinion in Chemical Biology. 12, 1, p. 93-101 9 p.

  Research output: Contribution to journal › Review article › peer-review
  155 Citations (Scopus)

• Discovery of the novel HLA-DRB1*16: 16 allele in a Taiwanese unrelated bone marrow stem cell donor by a sequence-based typing method and the probable haplotype associated with DRB1*16:16

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Oct 1 2012, In: International Journal of Immunogenetics. 39, 5, p. 445-447 3 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Discovery of the novel HLA-DRB1*10: 04 allele in a Taiwanese volunteer bone marrow donor and identification of the probable HLA-A, -B, -C and -DRB1 haplotype in association with DRB1*10:04

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Oct 1 2012, In: International Journal of Immunogenetics. 39, 5, p. 448-450 3 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Discovery of the novel HLA-DRB1*09: 01:08 allele in a Taiwanese volunteer bone marrow donor and identification of the probable HLA-A, HLA-B and HLA-DRB1 haplotype in association with DRB1*09:01:08

  Yang, K. L., Lee, S. K., Yang, S. Y., Kao, R. H., Lin, C. L. & Lin, P. Y., Apr 1 2013, In: International Journal of Immunogenetics. 40, 2, p. 149-150 2 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Discovery of the novel HLA-DRB1*04: 05:14 allele in a Taiwanese unrelated haematopoietic stem cell donor by a sequence-based typing method

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Aug 1 2013, In: International Journal of Immunogenetics. 40, 4, p. 326-327 2 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Discovery of the novel HLA-DRB1*03: 77 allele in a Taiwanese unrelated hematopoietic stem cell donor by a sequence-based typing method and identification of the probable HLA haplotype in association with DRB1*03:77

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Oct 1 2012, In: International Journal of Immunogenetics. 39, 5, p. 442-444 3 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method

  Yao, N., Xiao, W., Wang, X., Marik, J., Park, S. H., Takada, Y. & Lam, K. S., Jan 8 2009, In: Journal of Medicinal Chemistry. 52, 1, p. 126-133 8 p.

  Research output: Contribution to journal › Article › peer-review
  70 Citations (Scopus)

• Discovery of specific inhibitors for intestinal E. coli β -glucuronidase through in silico virtual screening

  Cheng, T. C., Chuang, K. H., Roffler, S. R., Cheng, K. W., Leu, Y. L., Chuang, C. H., Huang, C. C., Kao, C. H., Hsieh, Y. C., Chang, L. S., Cheng, T. L. & Chen, C. S., 2015, In: Scientific World Journal. 2015, 740815.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein

  Liu, S. L., Cheng, C. C., Chang, C. C., Mai, F. D., Wang, C. C., Lee, S. C., Ho, A. S., Chen, L. Y. & Chang, J., 2011, In: Journal of Biomedical Science. 18, 1, 52.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Discovery of pyrazolo[4,3-c]quinolines derivatives as potential anti-inflammatory agents through inhibiting of no production

  Tseng, C. H., Tung, C. W., Peng, S. I., Chen, Y. L., Tzeng, C. C. & Cheng, C. M., Jan 1 2018, In: Molecules. 23, 5, 1036.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy

  Chen, Y. F., Wu, C. H., Chen, L. H., Lee, H. W., Lee, J. C., Yeh, T. K., Chang, J. Y., Chou, M. C., Wu, H. L., Lai, Y. P., Song, J. S., Yeh, K. C., Chen, C. T., Lee, C. J., Shia, K. S. & Shen, M. R., Mar 24 2022, In: Journal of Medicinal Chemistry. 65, 6, p. 4767-4782 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Discovery of Potent Cysteine-Containing Dipeptide Inhibitors against Tyrosinase: A Comprehensive Investigation of 20 × 20 Dipeptides in Inhibiting Dopachrome Formation

  Tseng, T-S., Tsai, K-C., Chen, W-C., Wang, Y-T., Lee, Y-C., Lu, C-K., Don, M-J., Chang, C-Y., Lee, C-H., Lin, H-H., Hsu, H-J. & Hsiao, N-W., 2015, In: Journal of Agricultural and Food Chemistry. 63, 27, p. 6181-6188 8 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Discovery of Novel Protein Biomarkers in Urine for Diagnosis of Urothelial Cancer Using iTRAQ Proteomics

  Chen, C. J., Chou, C. Y., Shu, K. H., Chen, H. C., Wang, M. C., Chang, C. C., Hsu, B. G., Wu, M. S., Yang, Y. L., Liao, W. L., Yang, C., Hsiao, Y. T. & Huang, C. C., May 7 2021, In: Journal of Proteome Research. 20, 5, p. 2953-2963 11 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Discovery of Novel N-Glycoside and Non-Glycoside hSGLT2 Inhibitors for the Treatment of Type 2 Diabetes Mellitus

  Chang, C. Y., Ho, Y., Lin, S-J. & Liu, H. L., Aug 2019, In: International Journal of Diabetes Mellitus.

  Research output: Contribution to journal › Article › peer-review

• Discovery of Novel Irreversible HER2 Inhibitors for Breast Cancer Treatment

  Tang, J. Y., Ho, Y., Chang, C. Y. & Liu, H. L., Apr 2019, In: Journal of Biomedical Science and Engineering.

  Research output: Contribution to journal › Article › peer-review

• Discovery of novel bladder cancer biomarkers by comparative urine proteomics using iTRAQ technology

  Chen, Y. T., Chen, C. L., Chen, H. W., Chung, T., Wu, C. C., Chen, C. D., Hsu, C. W., Chen, M. C., Tsui, K. H., Chang, P. L., Chang, Y. S. & Yu, J. S., Nov 2010, In: Journal of Proteome Research. 9, 11, p. 5803-5815 13 p.

  Research output: Contribution to journal › Article › peer-review
  121 Citations (Scopus)

• Discovery of novel 5α-reductase type II inhibitors by pharmacophore modelling, virtual screening, molecular docking and molecular dynamics simulations

  Wang, J. L., Liu, H. L., Zhou, Z. L., Chen, W. H. & Ho, Y., Mar 4 2015, In: Molecular Simulation. 41, 4, p. 287-297 11 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Discovery of Natural Veterinary Herbal Medicine Products in Commercial Cow Milk by Using Nontargeted Profiling on LC–ESI–TOF Platform

  Wang, S. Y. & Liao, H. W., Apr 2022, In: Food Analytical Methods.

  Research output: Contribution to journal › Article › peer-review

• Discovery of indeno[1,2-c]quinoline derivatives as potent dual antituberculosis and anti-inflammatory agents

  Tseng, C. H., Tung, C. W., Wu, C. H., Tzeng, C. C., Chen, Y. H., Hwang, T. L. & Chen, Y. L., Jun 1 2017, In: Molecules. 22, 6, 1001.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Citations (Scopus)

• Discovery of HLA-DRB1*03: 20 allele in a Taiwanese volunteer hematopoietic stem cell donor and the probable HLA-A, -B, -C and -DRB1 haplotype in association with DRB1*03:20

  Yang, K. L., Lee, S. K., Yang, S. Y., Kao, R. H., Lin, C. L. & Lin, P. Y., Jun 1 2013, In: International Journal of Immunogenetics. 40, 3, p. 243-245 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Discovery of highly potent tyrosinase inhibitor, T1, with significant anti-melanogenesis ability by zebrafish in vivo assay and computational molecular modeling

  Chen, W-C., Tseng, T-S., Hsiao, N-W., Lin, Y-L., Wen, Z-H., Tsai, C-C., Lee, Y-C., Lin, H-H. & Tsai, K-C., 2015, In: Scientific Reports. 5

  Research output: Contribution to journal › Article › peer-review
  113 Citations (Scopus)

• Discovery of genes from feces correlated with colorectal cancer progression

  Lee, C. L., Huang, C. J., Yang, S. H., Chang, C. C., Huang, C. C., Chien, C. C. & Yang, R. N., Nov 1 2016, In: Oncology Letters. 12, 5, p. 3378-3384 7 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Discovery of enzymes for toluene synthesis from anoxic microbial communities

  Beller, H. R., Rodrigues, A. V., Zargar, K., Wu, Y. W., Saini, A. K., Saville, R. M., Pereira, J. H., Adams, P. D., Tringe, S. G., Petzold, C. J. & Keasling, J. D., May 1 2018, In: Nature Chemical Biology. 14, 5, p. 451-457 7 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• Discovery of a role of the novel hepatokine, hepassocin, in obesity

  Huang, R. L., Li, C. H., Du, Y. F., Cheng, K. P., Lin, C. H., Hu, C. Y., Wu, J. S., Chang, C. J., Wu, H. T. & Ou, H. Y., Jan 2020, In: BioFactors. 46, 1, p. 100-105 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Discovery of a potent cyclooxygenase-2 inhibitor, S4, through docking-based pharmacophore screening, in vivo and in vitro estimations

  Tseng, T. S., Chuang, S. M., Hsiao, N. W., Chen, Y. W., Lee, Y. C., Lin, C. C., Huang, C. & Tsai, K. C., Jan 1 2016, In: Molecular BioSystems. 12, 8, p. 2541-2551 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment

  Lin, T. E., Yang, C. R., Chou, C. H., Hsu, J. Y., Chao, M. W., Sung, T. Y., Hsieh, J. H., Huang, W. J. & Hsu, K. C., Feb 2022, In: Biomedicine and Pharmacotherapy. 146, 112459.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities

  Chao, S. W., Chen, L. C., Yu, C. C., Liu, C. Y., Lin, T. E., Guh, J. H., Wang, C. Y., Chen, C. Y., Hsu, K. C. & Huang, W. J., Jan 1 2018, In: European Journal of Medicinal Chemistry. 143, p. 792-805 14 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Discovery of akt kinase inhibitors through structure-based virtual screening and their evaluation as potential anticancer agents

  Chuang, C. H., Cheng, T. C., Leu, Y. L., Chuang, K. H., Tzou, S. C. & Chen, C. S., Feb 2 2015, In: International journal of molecular sciences. 16, 2, p. 3202-3212 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Citations (Scopus)

• Discovery of 5-(2′,4′-difluorophenyl)-salicylanilides as new inhibitors of receptor activator of NF-κ°B ligand (RANKL)-induced osteoclastogenesis

  Lee, C. C., Liu, F. L., Chen, C. L., Chen, T. C., Chang, D. M. & Huang, H. S., May 25 2015, In: European Journal of Medicinal Chemistry. 98, p. 115-126 12 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors

  Liou, J. P., Wu, Z. Y., Kuo, C. C., Chang, C. Y., Lu, P. Y., Chen, C. M., Hsieh, H. P. & Chang, J. Y., Jul 24 2008, In: Journal of Medicinal Chemistry. 51, 14, p. 4351-4355 5 p.

  Research output: Contribution to journal › Article › peer-review
  69 Citations (Scopus)

• Discovery and quantification of Irgacure-907 in commercial cow milk by using untargeted liquid chromatography high-resolution mass spectrometry

  Tseng, Z-R., Wei, C-C., Wang, S-Y. & Liao, H-W., 2020, In: Journal of Food Composition and Analysis.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Discovery and mechanisms of host defense to oncogenesis: targeting the β-defensin-1 peptide as a natural tumor inhibitor

  Sun, C. Q., Arnold, R. S., Hsieh, C. L., Dorin, J. R., Lian, F., Li, Z. & Petros, J. A., Jun 3 2019, In: Cancer Biology and Therapy. 20, 6, p. 774-786 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Discover the semantic topology in high-dimensional data

  Chiang, I. J., Jul 2007, In: Expert Systems with Applications. 33, 1, p. 256-262 7 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Discovering the two-step lag behavioral patterns of learners in the college SPOC platform

  Liu, Z., Cheng, H. N. H., Liu, S. & Sun, J., Jan 1 2017, In: International Journal of Information and Communication Technology Education. 13, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries

  Tung, C. P., Chen, I. C., Yu, C. M., Peng, H. P., Jian, J. W., Ma, S. H., Lee, Y. C., Jan, J. T. & Yang, A. S., Oct 12 2015, In: Scientific Reports. 5, 15053.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Discovering Latent Semantics in Web Documents Using Fuzzy Clustering

  Chiang, I-J., Liu, C. C. H., Tsai, Y. H. & Kumar, A., Dec 1 2015, In: IEEE Transactions on Fuzzy Systems. 23, 6, p. 2122-2134 13 p., 7042824.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)