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• Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway

  Yu, C. C., Hsu, M. J., Kuo, M. L., Chen, R. F. C., Chen, M. C., Bai, K. J., Yu, M. C., Chen, B. C. & Lin, C-H., Jun 15 2009, In: Journal of Immunology. 182, 12, p. 7916-7927 12 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway

  Lin, C-H., Yu, C. C., Hsu, M-J., Kuo, M. L., Chen, R. F. C. & Chen, B-C., Jul 6 2009.

  Research output: Contribution to conference › Poster › peer-review

• Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway

  Ko, W. C., Chen, B. C., Hsu, M. J., Tsai, C. T., Hong, C. Y. & Lin, C. H., Jan 2012, In: Acta Pharmacologica Sinica. 33, 1, p. 49-56 8 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Thrombin-induced connective tissue growth factor expression requires c-Src/JAK2/STAT3 signalling pathway in human lung fibroblasts

  Lin, C-H., Pai, H. C. & Chen, B-C., Jul 18 2010.

  Research output: Contribution to conference › Paper › peer-review

• Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells

  Lin, C-H., Shih, C. H. & Chen, B. C., Nov 15 2015, In: European Journal of Pharmacology. 767, p. 135-143 9 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Thrombin-induced NF-κB activation and IL-8/CXCL8 release is mediated by c-Src-dependent Shc, Raf-1, and ERK pathways in lung epithelial cells

  Lin, C. H., Yu, M. C., Chiang, C. C., Bien, M. Y., Chien, M. H. & Chen, B. C., May 2013, In: Cellular Signalling. 25, 5, p. 1166-1175 10 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)

• Thrombin induces cyclooxygenase-2 expression via the ERK and NF-κB pathways in human lung fibroblasts

  Shih, C. H., Bien, M. Y., Chiang, L. L., Su, C-L., Lin, C. H. & Chen, B. C., Sep 15 2009, In: European Journal of Pharmacology. 618, 1-3, p. 70-75 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1α translational pathway in colorectal cancer cells

  Chang, L. H., Chen, C-H., Huang, D. Y., Pai, H. C., Pan, S. L. & Teng, C. M., Apr 2011, In: Journal of Cellular Physiology. 226, 4, p. 1060-1068 9 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways

  Liu, J. F., Hou, S. M., Tsai, C. H., Huang, C. Y., Yang, W. H. & Tang, C. H., Apr 27 2012, In: Arthritis Research and Therapy. 14, 2, R91.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (Scopus)

• Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/ Akt-dependent NF-κB/p300 activation

  Cheng, S. E., Lee, I-T., Lin, C. C., Hsiao, L. D. & Yang, C. M., Jan 1 2014, In: Clinical Science. 127, 3, p. 171-183 13 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Thrombin induces inducible nitric oxide synthase expression via Ras, Raf-1, ERK, and NF-B signaling pathways in NR8383 lung macrophages

  Chen, B-C., Chi, C. Y. & Lin, C-H., Jun 26 2010.

  Research output: Contribution to conference › Poster › peer-review

• Thrombin induces inducible nitric oxide synthase expression via the MAPK, MSK1, and NF-κB signaling pathways in alveolar macrophages

  Lin, C. C., Shih, C. H., Yang, Y. L., Bien, M. Y., Lin, C. H., Yu, M. C., Sureshbabu, M. & Chen, B. C., Dec 15 2011, In: European Journal of Pharmacology. 672, 1-3, p. 180-187 8 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Thrombin induces NF-κB activation and IL-8/CXCL8 expression in lung epithelial cells by a Rac1-dependent PI3K/Akt pathway

  Lin, C-H., Cheng, H. W., Ma, H. P., Wu, C. H., Hong, C. Y. & Chen, B. C., Mar 25 2011, In: Journal of Biological Chemistry. 286, 12, p. 10483-10494 12 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• Thrombin induces NF-B activation and IL-8/CXCL8 expression in lung epithelial cells by Rac1 dependent PI3K/Akt pathway

  Chen, B-C., Cheng, H. W. & Lin, C-H., Jul 4 2009.

  Research output: Contribution to conference › Poster › peer-review

• Thrombin mediates migration of rat brain astrocytes via PLC, Ca ²⁺, CaMKII, PKCα, and AP-1-dependent matrix metalloproteinase-9 expression

  Lin, C. C., Lee, I-T., Wu, W. B., Liu, C. J., Hsieh, H. L., Hsiao, L. D., Yang, C. C. & Yang, C. M., Jan 1 2013, In: Molecular Neurobiology. 48, 3, p. 616-630 15 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Thrombin upregulates PAI-1 and mesothelial–mesenchymal transition through PAR-1 and contributes to tuberculous pleural fibrosis

  Hsieh, C. Y., Sheu, J. R., Yang, C. H., Chen, W. L., Tsai, J. H. & Chung, C. L., Oct 2 2019, In: International Journal of Molecular Sciences. 20, 20, 5076.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Thromboelastogram Directed Anticoagulation After Left Ventricular Assist Device Implantation

  Abdou, M., Chen, R. J., Wang, I., Gleissner, E., Pickrell, J., Caccamo, M. & Hadi, A., Apr 1 2017, In: Journal of Heart and Lung Transplantation. 36, 4, p. S248-S249

  Research output: Contribution to journal › Conference article › peer-review

• Thromboelastographic study of thrombosis in the implantable central venous access device

  Wen, Y. R., Ho, W. Y., Sun, W. Z., Or, C. H., Yeh, M. Y., Yao, C. W. & Tai, Y-T., Dec 1997, In: Acta Anaesthesiologica Taiwanica. 35, 4, p. 223-8 6 p.

  Research output: Contribution to journal › Article › peer-review

  12 Citations (Scopus)

• Thromboembolic and bleeding risk of periprocedural bridging anticoagulation: A systematic review and meta-analysis

  Kuo, H. C., Liu, F. L., Chen, J. T., Cherng, Y. G., Tam, K. W. & Tai, Y. H., May 1 2020, In: Clinical Cardiology. 43, 5, p. 441-449 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  5 Citations (Scopus)

• Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

  EXTEND Investigators & the EXTEND Investigators, May 9 2019, In: The New England journal of medicine. 380, 19, p. 1795-1803 9 p.

  Research output: Contribution to journal › Article › peer-review
  344 Citations (Scopus)

• Thrombolysis in an acute ischemic stroke patient with rivaroxaban anticoagulation: A case report

  Chao, Y. T., Hu, C. J. & Chan, L., Feb 1 2019, In: Medicine. 98, 8, p. e14560

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Thrombomodulin and disseminated intravascular coagulation

  Lin, S. M. & Kuo, H. P., Jan 1 2013, Disseminated Intravascular Coagulation (DIC): Clinical Manifestations, Diagnosis and Treatment Options. Nova Science Publishers, Inc., p. 41-56 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Thrombomodulin gene polymorphism (C1418T) is associated with the development of coronary allograft vasculopathy

  Tsai, C. S., Lin, Y. W., Shih, C. C., Chen, Y. H., Lin, C. Y., Tsai, Y. T., Lee, C. Y., Shih, C. M., Huang, C. Y., Chung, H. H. & Lin, F. Y., Sep 2013, In: European Journal of Inflammation. 11, 3, p. 685-696 12 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition (EMT)

  Chang, Y. J., Cheng, Y. W., Lin, R. K., Huang, C. C., Chen, W. T. L., Ke, T. W. & Wei, P. L., Aug 2016, In: PLoS ONE. 11, 8, e0160550.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Thrombomodulin is upregulated in cardiomyocytes during cardiac hypertrophy and prevents the progression of contractile dysfunction

  Li, Y. H., Chung, H. C., Luo, C. Y., Chao, T. H., Shyu, K. G., Shi, G. Y. & Wu, H. L., Dec 2010, In: Journal of Cardiac Failure. 16, 12, p. 980-990 11 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Thrombomodulin mediates the migration of cervical cancer cells through the regulation of epithelial-mesenchymal transition biomarkers

  Tai, C-J., Cheng, C-W., Su, H. Y., Chen, W-Y., Wu, C. T., Lin, F-Y., Wang, C. K., Tai, C-J. & Wei, P-L., Jan 2014, In: Tumor Biology. 35, 1, p. 47-54 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Thrombomodulin mediates the migratory ability of hormone-independent prostate cancer cells through the regulation of epithelial-to-mesenchymal transition biomarkers

  Wu, C. T., Chang, Y. J., Chen, M. F., Liu, J. J., Wei, P. L., Wang, W. & Liu, H. H., 2014, In: Tumor Biology. 35, 6, p. 6047-6054 8 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Thrombomodulin mediates the progression of epithelial ovarian cancer cells

  Chen, L. M., Wang, W., Lee, J. C., Chiu, F. H., Wu, C. T., Tai, C. J., Wang, C. K., Tai, C. J., Huang, M. T. & Chang, Y. J., Dec 2013, In: Tumor Biology. 34, 6, p. 3743-3751 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Thrombomodulin regulates monocye differentiation via PKCÎ and ERK1/2 pathway in vitro and in atherosclerotic artery

  Tsai, C. S., Lin, Y. W., Huang, C-Y., Shih, C-M., Tsai, Y. T., Tsao, N-W., Lin, C. S., Shih, C. C., Jeng, H. & Lin, F-Y., Dec 2 2016, In: Scientific Reports. 6, 38421.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Thrombophilia associated with obesity in ethnic Chinese

  Chan, P., Lin, T. H., Pan, W. H. & Lee, Y. H., 1995, In: International Journal of Obesity. 19, 10, p. 756-759 4 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Thrombophilia in patients with hypercholesterolemia

  Chan, P., Tomlinsoin, B., Tsai, C. W., Pan, W. H. & Lee, Y. S., 1996, In: Metabolism: Clinical and Experimental. 45, 8, p. 966-969 4 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Thrombophilia in patients with hypertriglyceridemia

  Chan, P., Huang, T. Y., Shieh, S. M., Lin, T. S. & Tsai, C. W., 1997, In: Journal of Thrombosis and Thrombolysis. 4, 3-4, p. 425-429 5 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Thrombopoietic cytokines in patients with hepatitis C virus-associated immune thrombocytopenia

  Huang, C. E., Chen, Y. Y., Chang, J. J., Kuan, F. C., Lee, K. D., Lu, C. H., Lung, J., Shen, C. H. & Chen, C. C., Jan 2 2017, In: Hematology. 22, 1, p. 54-60 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Thromboses after estrogen hormone replacement, progesterone or tamoxifen therapy in patients with elevated blood levels of homocysteine

  Dai, M. S., Lee, S. C., Ho, C. L., Chen, Y. C., Kao, W. Y. & Chao, T. Y., 2001, In: American Journal of Hematology. 68, 2, p. 135 1 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Thrombosis of the inferior vena cava in a pregnant woman with nephrotic syndrome - Diagnostic and therapeutic dilemma

  Tien, Y. C., Yang, C. W., Ng, K. K., Wu, M. S., Lai, P. C. & Huang, C. C., 1999, In: Nephrology Dialysis Transplantation. 14, 1, p. 210-213 4 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Thrombospondin 2 promotes il-6 production in osteoarthritis synovial fibroblasts via the pi3k/ akt/nf-κb pathway

  Hou, C. H., Tang, C. H., Chen, P. C. & Liu, J. F., 2021, In: Journal of Inflammation Research. 14, p. 5955-5967 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Thrombospondin-2 promotes prostate cancer bone metastasis by the up-regulation of matrix metalloproteinase-2 through down-regulating miR-376c expression

  Chen, P. C., Tang, C. H., Lin, L. W., Tsai, C. H., Chu, C. Y., Lin, T. H. & Huang, Y. L., Jan 25 2017, In: Journal of Hematology and Oncology. 10, 1, 33.

  Research output: Contribution to journal › Article › peer-review
  39 Citations (Scopus)

• Thrombospondin 2 promotes tumor metastasis by inducing matrix metalloproteinase-13 production in lung cancer cells

  Liu, J. F., Lee, C. W., Tsai, M. H., Tang, C. H., Chen, P. C., Lin, L. W., Lin, C. Y., Lu, C. H., Lin, Y. F., Yang, S. H. & Chao, C. C., Sep 2018, In: Biochemical Pharmacology. 155, p. 537-546 10 p.

  Research output: Contribution to journal › Article › peer-review
  44 Citations (Scopus)

• Thrombospondin-2 stimulates MMP-9 production and promotes osteosarcoma metastasis via the PLC, PKC, c-Src and NF-κB activation

  Liu, J. F., Chen, P. C., Chang, T. M. & Hou, C. H., 2020, (Accepted/In press) In: Journal of Cellular and Molecular Medicine. 24, 21, p. 12826-12839 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• Thromboxane a2 mediates iron-overload cardiomyopathy in mice through calcineurin-nuclear factor of activated t cells signaling pathway

  Lin, H., Li, H. F., Lian, W. S., Chen, H. H., Lan, Y. F., Lai, P. F. & Cheng, C. F., 2013, In: Circulation Journal. 77, 10, p. 2586-2595 10 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Thromboxane B₂ transformed from arachidonic acid in carrageenin-induced granuloma

  Chang, W. C., Murota, S. I. & Tsurufuji, S., 1977, In: Prostaglandins. 13, 1, p. 17-24 8 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• Thrombus Associated with the Left Ventricular Vent: Incidental Diagnosis byTransesophageal Echocardiography

  Liu, M. C., Cherng, Y-G. & Chang, H. C., Aug 2013, In: Journal of Experimental and Clinical Medicine(Taiwan). 5, 4, p. 150-151 2 p.

  Research output: Contribution to journal › Article › peer-review

• Thrombus-specific theranostic nanocomposite for codelivery of thrombolytic drug, algae-derived anticoagulant and NIR fluorescent contrast agent

  Chang, L. H., Chuang, E. Y., Cheng, T. M., Lin, C., Shih, C. M., Wu, A. TH., Jheng, P. R., Lu, H. Y., Shih, C. C. & Mi, F. L., 2021, In: Acta Biomaterialia. 134, p. 686-701 16 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Through diffusion tensor magnetic resonance imaging to evaluate the original properties of neural pathways of patients with partial seizures and secondary generalization by individual anatomic reference atlas

  Peng, S. J., Harnod, T., Tsai, J. Z., Huang, C. C., Ker, M. D., Chiou, J. C., Chiueh, H., Wu, C. Y. & Hsin, Y. L., Jan 1 2014, In: BioMed Research International. 2014, 419376.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• THR Simulator - The software for generating radiographs of THR prosthesis

  Wu, T. Y., Yang, R. S., Fuh, C. S., Hou, S. M. & Liaw, C. K., Mar 24 2009, In: BMC Musculoskeletal Disorders. 10, 8.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Thunderclap headache: Images from headache

  Kuo, C. L., Chiu, Y. H., Chen, J. D., How, C. K. & Lam, C., Jul 2010, In: Headache. 50, 7, p. 1201-1202 2 p.

  Research output: Contribution to journal › Article › peer-review

• Thy-1, a novel marker for angiogenesis upregulated by inflammatory cytokines

  Lee, W. S., Jain, M. K., Arkonac, B. M., Zhang, D., Shaw, S. Y., Kashiki, S., Maemura, K., Lee, S. L., Hollenberg, N. K., Lee, M. E. & Haber, E., May 4 1998, In: Circulation Research. 82, 8, p. 845-851 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  84 Citations (Scopus)

• Thy-1-Induced Migration Inhibition in Vascular Endothelial Cells through Reducing the RhoA Activity

  Wen, H. C., Kao, C., Hsu, R. C., Huo, Y. N., Ting, P. C., Chen, L. C., Hsu, S. P., Juan, S. H. & Lee, W. S., Apr 17 2013, In: PLoS One. 8, 4, e61506.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Thymectomy in patients with myasthenia gravis increases the risk of autoimmune rheumatic diseases: a nationwide cohort study

  Chang, C-C., Lin, T-M., Chang, Y-S., Chen, W-S., Sheu, J-J., Chen, Y-H. & Chen, J-H., Jan 1 2019, In: Rheumatology. 58, 1, p. 135-143 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Thymic carcinoma: Ten years' experience in twenty patients

  Hsu, C. P., Chen, C. Y., Chen, C. L., Lin, C. T., Hsu, N. Y., Wang, J. H. & Wang, P. Y., 1994, In: Journal of Thoracic and Cardiovascular Surgery. 107, 2, p. 615-620 6 p.

  Research output: Contribution to journal › Article › peer-review
  141 Citations (Scopus)