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Author

  • Paul Chan
2017
2 Citations (Scopus)

Alirocumab for the treatment of hypercholesterolemia

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Mar 20 2017, (Accepted/In press) In : Expert Opinion on Biological Therapy. p. 1-11 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai

Peng, S., Shen, T., Liu, J., Tomlinson, B., Sun, H., Chen, X., Chan, P., Kuang, Y., Zheng, L., Wu, H., Ding, X., Qian, D., Shen, Y., Gao, P., Fan, H., Liu, Z. & Zhang, Y., Oct 2017, In : Aging and Disease. 8, 5, p. 558-569 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The ODYSSEY DM-DYSLIPIDEMIA trial: Confirming the benefits of alirocumab in diabetic mixed dyslipidemia

Chan, P., Shao, L., Tomlinson, B. & Liu, Z. M., Dec 1 2017, In : Annals of Translational Medicine. 5, 23, 477.

Research output: Contribution to journalEditorial

Effectiveness of endurance exercise training in patients with coronary artery disease: A meta-analysis of randomised controlled trials

Chen, Y. C., Tsai, J. C., Liou, Y. M. & Chan, P., Jun 1 2017, In : European Journal of Cardiovascular Nursing. 16, 5, p. 397-408 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2020

An evaluation of liraglutide including its efficacy and safety for the treatment of obesity

Lin, C. H., Shao, L., Zhang, Y. M., Tu, Y. J., Zhang, Y., Tomlinson, B., Chan, P. & Liu, Z., Feb 11 2020, In : Expert Opinion on Pharmacotherapy. 21, 3, p. 275-285 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Evaluating the efficacy and safety of atorvastatin + ezetimibe in a fixed-dose combination for the treatment of hypercholesterolemia

Ma, Y. B., Chan, P., Zhang, Y., Tomlinson, B. & Liu, Z., May 24 2019, In : Expert Opinion on Pharmacotherapy. 20, 8, p. 917-928 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Response to the letter "no evidence to support high-intensity statin in Chinese patients with coronary heart disease"

Tomlinson, B., Hu, M., Zhang, Y., Liu, Z. M. & Chan, P., Apr 15 2016, In : International Journal of Cardiology. 209, p. 192-193 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

Single-pill combinations for hypertension: first line treatment for all?

Shao, L., Chan, P., Tomlinson, B., Zhang, Y. & Liu, Z. M., Jan 2 2019, In : Current Medical Research and Opinion.

Research output: Contribution to journalArticle

Open Access
2018

Elevated expression of miR302-367 in Endothelial cells inhibits developmental angiogenesis via CDC42/CCND1 mediated signaling pathways

Pi, J., Liu, J., Zhuang, T., Zhang, L., Sun, H., Chen, X., Zhao, Q., Kuang, Y., Peng, S., Zhou, X., Yu, Z., Tao, T., Tomlinson, B., Chan, P., Tian, Y., Fan, H., Liu, Z., Zheng, X., Morrisey, E. & Zhang, Y., Jan 1 2018, In : Theranostics. 8, 6, p. 1511-1526 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2019

An evaluation of pitavastatin for the treatment of hypercholesterolemia

Chan, P., Shao, L., Tomlinson, B., Zhang, Y. & Liu, Z. M., Jan 2 2019, In : Expert Opinion on Pharmacotherapy. 20, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Tanshinone IIA Induces Heme Oxygenase 1 Expression and Inhibits Cyclic Strain-Induced Interleukin 8 Expression in Vascular Endothelial Cells

Zhuang, S., Cheng, T-H., Shih, N. L., Liu, J. C., Chen, J. J., Hong, H. J. & Chan, P., Apr 1 2016, In : American Journal of Chinese Medicine. 44, 2, p. 377-388 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Effects of glucose-lowering drugs on cardiovascular outcomes in patients with type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Nov 1 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 11, p. 1267-1271 5 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Current status of personalized medicine based on pharmacogenetics in cardiovascular medicine

Tomlinson, B., Hu, M., Waye, M. M. Y., Chan, P. & Liu, Z. M., Jan 2 2016, In : Expert Review of Precision Medicine and Drug Development. 1, 1, p. 5-8 4 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)
2019

Lysophosphatidylcholine-induced cytotoxicity and protection by heparin in mouse brain bEND.3 endothelial cells

Tsai, T. Y., Leong, I. L., Cheng, K. S., Shiao, L. R., Su, T. H., Wong, K. L., Chan, P. & Leung, Y. M., Feb 1 2019, In : Fundamental and Clinical Pharmacology. 33, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

The Effect of Photoluminescence of Bioceramic Irradiation on Middle Cerebral Arterial Occlusion in Rats

Zhang, L., Chan, P., Liu, Z. M., Hwang, L-L., Lin, K. C., Chan, W. P., Leung, T-K. & Choy, C-S., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 7230962.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2019

Quercetin depletes intracellular Ca2+ stores and blunts ATP-triggered Ca2+ signaling in bEnd.3 endothelial cells

Chen, C. Y., Hour, M. J., Shiao, L. R., Wong, K. L., Leung, Y. M., Chan, P. & So, E. C., Jan 1 2019, (Accepted/In press) In : Fundamental and Clinical Pharmacology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

An overview of new GLP-1 receptor agonists for type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Feb 1 2016, In : Expert Opinion on Investigational Drugs. 25, 2, p. 145-158 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2019

Endothelial Forkhead Box Transcription Factor P1 Regulates Pathological Cardiac Remodeling Through Transforming Growth Factor-β1-Endothelin-1 Signal Pathway

Liu, J., Zhuang, T., Pi, J., Chen, X., Zhang, Q., Li, Y., Wang, H., Shen, Y., Tomlinson, B., Chan, P., Yu, Z., Cheng, Y., Zheng, X., Reilly, M., Morrisey, E., Zhang, L., Liu, Z. & Zhang, Y., Aug 20 2019, In : Circulation. 140, 8, p. 665-680 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Investigational glucagon-like peptide-1 agonists for the treatment of obesity

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Oct 2 2016, In : Expert Opinion on Investigational Drugs. 25, 10, p. 1167-1179 13 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)
2017

A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability

Pi, J., Tao, T., Zhuang, T., Sun, H., Chen, X., Liu, J., Cheng, Y., Yu, Z., Zhu, H. H., Gao, W. Q., Suo, Y., Wei, X., Chan, P., Zheng, X., Tian, Y., Morrisey, E., Zhang, L. & Zhang, Y., Jan 6 2017, In : Circulation Research. 120, 1, p. 85-98 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2018

Metformin transporter pharmacogenomics: insights into drug disposition—where are we now?

Chan, P., Shao, L., Tomlinson, B., Zhang, Y. & Liu, Z. M., Nov 2 2018, In : Expert Opinion on Drug Metabolism and Toxicology. 14, 11, p. 1149-1159 11 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2 Citations (Scopus)
2016

Higher prevalence of elevated LDL-C than non-HDL-C and low statin treatment rate in elderly community-dwelling Chinese with high cardiovascular risk

Kuang, Y. S., Li, X., Chen, X., Sun, H., Tomlinson, B., Chan, P., Zheng, L., Pi, J., Peng, S., Wu, H., Ding, X., Qian, D., Shen, Y., Yu, Z., Fan, L., Chen, M., Fan, H., Liu, Z. & Zhang, Y., Sep 30 2016, In : Scientific Reports. 6, 34268.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese

Fan, H., Li, X., Zheng, L., Chen, X., Lan, Q., Wu, H., Ding, X., Qian, D., Shen, Y., Yu, Z., Fan, L., Chen, M., Tomlinson, B., Chan, P., Zhang, Y. & Liu, Z., Feb 17 2016, In : Scientific Reports. 6, 21521.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2019

Endothelial Foxp1 Suppresses Atherosclerosis via Modulation of Nlrp3 Inflammasome Activation

Zhuang, T., Liu, J., Chen, X., Zhang, L., Pi, J., Sun, H., Li, L., Bauer, R., Wang, H., Yu, Z., Zhang, Q., Tomlinson, B., Chan, P., Zheng, X., Morrisey, E., Liu, Z., Reilly, M. & Zhang, Y., Aug 30 2019, In : Circulation Research. 125, 6, p. 590-605 16 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
2017

Vasculopathy in the setting of cardiorenal syndrome: Roles of protein-bound uremic toxins

Guo, J., Lu, L., Hua, Y., Huang, K., Wang, I., Huang, L., Fu, Q., Chen, A., Chan, P., Fan, H., Liu, Z. M. & Wang, B. H., 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 1, p. H1-H13

Research output: Contribution to journalReview article

14 Citations (Scopus)
2019

Antagonism of Ca 2+ -sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells

Chen, C. Y., Hour, M. J., Lin, W. C., Wong, K. L., Shiao, L. R., Cheng, K. S., Chan, P. & Leung, Y. M., Jan 1 2019, In : Naunyn-Schmiedeberg's Archives of Pharmacology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Liraglutide for weight management: benefits and risks

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Mar 4 2017, In : Current Medical Research and Opinion. 33, 3, p. 537-539 3 p.

Research output: Contribution to journalComment/debate

Evolocumab for the treatment of hypercholesterolemia

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Aug 13 2017, (Accepted/In press) In : Expert Opinion on Biological Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Valproic acid inhibits ATP-triggered Ca2+release via a p38-dependent mechanism in bEND.3 endothelial cells

Leong, I. L., Tsai, T. Y., Wong, K. L., Shiao, L. R., Cheng, K. S. & Chan, P., Oct 1 2018, In : Fundamental and Clinical Pharmacology. 32, 5, p. 499-506 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Cell-Specific Effects of GATA (GATA Zinc Finger Transcription Factor Family)-6 in Vascular Smooth Muscle and Endothelial Cells on Vascular Injury Neointimal Formation

Zhuang, T., Liu, J., Chen, X., Pi, J., Kuang, Y., Wang, Y., Tomlinson, B., Chan, P., Zhang, Q., Li, Y., Yu, Z., Zheng, X., Reilly, M., Morrisey, E., Zhang, L., Liu, Z. & Zhang, Y., May 1 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 5, p. 888-901 14 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2017

Evaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Feb 1 2017, In : Expert Opinion on Drug Metabolism and Toxicology. 13, 2, p. 211-223 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

Statin responses in chinese patients

Tomlinson, B., Chan, P. & Liu, Z. M., Jan 1 2018, In : Journal of Atherosclerosis and Thrombosis. 25, 2, p. 199-202 4 p.

Research output: Contribution to journalLetter

11 Citations (Scopus)
2016

Eicosapentaenoic acid triggers Ca2+ release and Ca2+ influx in mouse cerebral cortex endothelial bEND.3 cells

Wu, K. C., Wong, K. L., Wang, M. L., Shiao, L. R., Leong, I. L., Gong, C. L., Cheng, K. S., Chan, P. & Leung, Y. M., Nov 21 2016, (Accepted/In press) In : Journal of Physiological Sciences. p. 1-9 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Attaining cholesterol goals: will aiming for lower targets improve the score?

Leong, I. L., Tomlinson, B., Zhang, Y., Chan, P. & Liu, Z. M., Dec 14 2017, (Accepted/In press) In : Current Medical Research and Opinion. p. 1-3 3 p.

Research output: Contribution to journalArticle

2019

Dysfunctional endothelial-derived microparticles promote inflammatory macrophage formation via NF-кB and IL-1β signal pathways

Wang, Y., Liu, J., Chen, X., Sun, H., Peng, S., Kuang, Y., Pi, J., Zhuang, T., Zhang, L., Yu, Z., Tomlinson, B., Chan, P., Chen, Y., Zhang, Y. & Li, Y., Jan 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 1, p. 476-486 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2017

Perturbation of Akt Signaling, Mitochondrial Potential, and ADP/ATP Ratio in Acidosis-Challenged Rat Cortical Astrocytes

Wu, K. C., Cheng, K. S., Wang, Y. W., Chen, Y. F., Wong, K. L., Su, T. H., Chan, P. & Leung, Y. M., May 1 2017, In : Journal of Cellular Biochemistry. 118, 5, p. 1108-1117

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Prediction of response to lipid-lowering treatments

Tomlinson, B., Chan, P. & Liu, Z-M., Nov 2 2018, 6 ed. 3 p. (Expert Review of Precision Medicine and Drug Development)

Research output: Book/ReportBook