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  • Ray-Jade Chen
2017

Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Chang, Y. M., Chang, H. H., Tsai, C. C., Lin, H. J., Ho, T. J., Ye, C. X., Chiu, P. L., Chen, Y. S., Chen, R. J., Huang, C. Y. & Lin, C. C., Mar 31 2017, In : BMC Complementary and Alternative Medicine. 17, 1, 184.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2018

C-terminus of Hsc70-interacting protein (CHIP) enhances stemness properties of human Wharton’s jelly mesenchymal stem cell

Yang, C. K., Feng, C. C., Lo, J. F., Chen, J. W., Padma, V. V., Lai, C. H., Chen, T. S., Chen, R. J., Liao, P. H. & Huang, C. Y., Nov 17 2018, In : Biotechnic and Histochemistry. 93, 8, p. 632-639 8 p.

Research output: Contribution to journalArticle

Epithelioid Angiomyolipoma of the Liver

Huang, Y. M., Wei, P. L. & Chen, R. J., Jan 1 2018, In : Journal of Gastrointestinal Surgery. 22, 1, p. 175-176 2 p.

Research output: Contribution to journalArticle

2017

β-Catenin overexpression causes an increase in inflammatory cytokines and NF-kB activation in cardiomyocytes

Lin, J. C., Chang, R. L., Chen, Y. F., Yang, J. J., Baskaran, R., Chung, L. C., Chen, R. J., Day, C. H., Vijaya Padma, V. & Huang, C. Y., 2017, In : Cellular and Molecular Biology. 63, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016

Developing a scalable, cross-facility-based therapeutic decision reminder engine

Yang, C. Y., Tsai, M. C., Chen, R. J., Lo, Y. S., Kang, L. Y. & Liu, C. T., 2016, WCECS 2016 - World Congress on Engineering and Computer Science 2016. Newswood Limited, Vol. 2225. p. 201-207 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018
9 Citations (Scopus)
2017
7 Citations (Scopus)
2019
Open Access
3 Citations (Scopus)
2016

Rates of susceptibility of carbapenems, ceftobiprole, and colistin against clinically important bacteria collected from intensive care units in 2007: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Jean, S., Lee, W-S., Yu, K. W., Liao, C. H., Hsu, C-W., Chang, F. Y., Ko, W. C., Chen, R-J., Wu, J. J., Chen, Y. H., Chen, Y. S., Liu, J. W., Lu, M. C., Lam, C., Liu, C. Y. & Hsueh, P. R., Dec 1 2016, In : Journal of Microbiology, Immunology and Infection. 49, 6, p. 969-976

Research output: Contribution to journalArticle

16 Citations (Scopus)
2017

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte

Wen, S. Y., Velmurugan, B. K., Day, C. H., Shen, C. Y., Chun, L. C., Tsai, Y. C., Lin, Y. M., Chen, R. J., Kuo, C. H. & Huang, C. Y., 2017, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Chen, Y. F., Lee, N. H., Pai, P. Y., Chung, L. C., Shen, C. Y., Rajendran, P., Chen, Y. F., Chen, R. J., Padma Viswanadha, V., Kuo, W. W. & Huang, C. Y., Sep 3 2017, In : Journal of Receptors and Signal Transduction. 37, 5, p. 493-499 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Tanshinone IIA inhibits β-catenin nuclear translocation and IGF-2R activation via estrogen receptors to suppress angiotensin II-induced H9c2 cardiomyoblast cell apoptosis

Chen, Y. F., Day, C. H., Lee, N. H., Chen, Y. F., Yang, J. J., Lin, C. H., Chen, R. J., Rajendran, P., Viswanadha, V. P. & Huang, C. Y., Sep 30 2017, In : International Journal of Medical Sciences. 14, 12, p. 1284-1291 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Major pancreatic duct continuity is the crucial determinant in the management of blunt pancreatic injury: a pancreatographic classification

Lin, B. C., Wong, Y-C., Chen, R. J., Liu, N. J., Wu, C. H., Hwang, T. L. & Hsu, Y. P., Mar 9 2017, (Accepted/In press) In : Surgical Endoscopy and Other Interventional Techniques. p. 1-10 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2020
1 Citation (Scopus)
2018

The preventive effects of edible folic acid on cardiomyocyte apoptosis and survival in early onset triple-transgenic Alzheimer's disease model mice

Lin, K. H., Chiu, C. H., Kuo, W. W., Ju, D. T., Shen, C. Y., Chen, R. J., Lin, C. C., Viswanadha, V. P., Liu, J. S., Huang, R. F. S. & Huang, C. Y., Jan 2018, In : Environmental Toxicology. 33, 1, p. 83-92

Research output: Contribution to journalArticle

6 Citations (Scopus)

HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy

Huang, C. Y., Lee, F. L., Peng, S. F., Lin, K. H., Chen, R. J., Ho, T. J., Tsai, F. J., Padma, V. V., Kuo, W. W. & Huang, C. Y., Feb 2018, In : Journal of Cellular Physiology. 233, 2, p. 979-989

Research output: Contribution to journalArticle

17 Citations (Scopus)
2017

Relation of polymorphism of arsenic metabolism genes to arsenic methylation capacity and developmental delay in preschool children in Taiwan

Hsieh, R. L., Su, C. T., Shiue, H. S., Chen, W. J., Huang, S. R., Lin, Y. C., Lin, M. I., Mu, S. C., Chen, R. J. & Hsueh, Y. M., Apr 15 2017, In : Toxicology and Applied Pharmacology. 321, p. 37-47 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells

Chang, Y. M., Asokan Shibu, M., Tsai, C. T., Tsai, C. C., Lin, S. L., Chang, C. C., Viswanadha, V. P., Chen, R. J., Chang, J. H. M. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2 Citations (Scopus)

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest

Lu, W. J., Wu, G. J., Chen, R. J., Chang, C. C., Lien, L. M., Chiu, C. C., Tseng, M. F., Huang, L. T. & Lin, K. H., Aug 1 2018, In : Food and Function. 9, 8, p. 4500-4507 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., Nov 14 2018, In : Journal of Clinical Medicine. 7, 11

Research output: Contribution to journalArticle

2016

Anti-apoptotic and pro-survival effect of alpinate oxyphyllae fructus (AOF) in a D-galactose-induced aging heart

Chang, Y. M., Chang, H. H., Kuo, W. W., Lin, H. J., Yeh, Y. L., Viswanadha, V. P., Tsai, C. C., Chen, R. J., Chang, H. N. & Huang, C. Y., Mar 29 2016, In : International Journal of Molecular Sciences. 17, 4, 466.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2018

Fenofibrate induced PPAR alpha expression was attenuated by oestrogen receptor alpha overexpression in Hep3B cells

Jeng, L. B., Velmurugan, B. K., Hsu, H. H., Wen, S. Y., Shen, C. Y., Lin, C. H., Lin, Y. M., Chen, R. J., Kuo, W. W. & Huang, C. Y., Feb 1 2018, In : Environmental Toxicology. 33, 2, p. 234-247 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

Alpinate Oxyphyllae Fructus Inhibits IGFII-Related Signaling Pathway to Attenuate Ang II-Induced Pathological Hypertrophy in H9c2 Cardiomyoblasts

Tsai, C. T., Chang, Y. M., Lin, S. L., Chen, Y. S., Yeh, Y. L., Padma, V. V., Tsai, C. C., Chen, R. J., Ho, T. J. & Huang, C. Y., Mar 1 2016, In : Journal of Medicinal Food. 19, 3, p. 300-309 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2017

Lactobacillus paracasei GMNL-32 exerts a therapeutic effect on cardiac abnormalities in NZB/W F1 mice

Hu, W. S., Rajendran, P., Tzang, B. S., Yeh, Y. L., Shen, C. Y., Chen, R. J., Ho, T. J., Padma, V. V., Chen, Y. H. & Huang, C. Y., Sep 1 2017, In : PLoS One. 12, 9, e0185098.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2019

Deep sea minerals ameliorate diabetic-induced inflammation via inhibition of TNFα signaling pathways

Lu, C. H., Ou, H. C., Day, C. H., Chen, H. I., Pai, P. Y., Lee, C. Y., Chen, R. J., Chang, R. L., PadmaViswanadha, V., Hsieh, D. J. Y. & Huang, C. Y., Jan 1 2019, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage

Pandey, S., Kuo, W. W., Ho, T. J., Yeh, Y. L., Shen, C. Y., Chen, R. J., Chang, R. L., Pai, P. Y., Padma, V. V., Huang, C. Y. & Huang, C. Y., Jan 1 2019, In : Journal of Cellular Biochemistry. 120, 10, p. 16956-16966 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Protective effect of autologous transplantation of resveratrol preconditioned adipose-derived stem cells in the treatment of diabetic liver dysfunction in rat model

Chen, T. S., Ju, D. T., Day, C. H., Yeh, Y. L., Chen, R. J., Viswanadha, V. P., Chang, R. L., Lin, Y. C., Yao, C. H. & Huang, C. Y., Sep 1 2019, In : Journal of Tissue Engineering and Regenerative Medicine. 13, 9, p. 1629-1640 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

CHIP attenuates lipopolysaccharide-induced cardiac hypertrophy and apoptosis by promoting NFATc3 proteasomal degradation

Chao, C. N., Lai, C. H., Badrealam, K. F., Lo, J. F., Shen, C. Y., Chen, C. H., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., Nov 1 2019, In : Journal of Cellular Physiology. 234, 11, p. 20128-20138 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP-2/9 expression via p38 MAPK pathway

Hsu, H. H., Kuo, W. W., Day, C. H., Shibu, M. A., Li, S. Y., Chang, S. H., Shih, H. N., Chen, R. J., Viswanadha, V. P., Kuo, Y. H. & Huang, C. Y., 2016, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Therapeutic effectiveness of percutaneous drainage and factors for performing an interval appendectomy in pediatric appendiceal abscess

Luo, C. C., Cheng, K. F., Huang, C. S., Lo, H-C., Wu, S. M., Huang, H. C., Chien, W. K. & Chen, R. J., Oct 18 2016, In : BMC Surgery. 16, 1, 72.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Does age affect the outcomes and management of pediatric appendicitis in Taiwan?

Lo, H-C., Chien, W. K., Huang, C. S., Wu, S. M., Huang, H. C., Chen, R. J. & Luo, C. C., Jan 5 2016, (Accepted/In press) In : Formosan Journal of Surgery.

Research output: Contribution to journalArticle

2017

Trends in diagnostic approaches for pediatric appendicitis: Nationwide population-based study

Luo, C. C., Chien, W. K., Huang, C. S., Lo, H. C., Wu, S. M., Huang, H. C., Chen, R. J. & Chao, H. C., Nov 3 2017, In : BMC Pediatrics. 17, 1, 188.

Research output: Contribution to journalArticle

2018

E4BP4 inhibits AngII-induced apoptosis in H9c2 cardiomyoblasts by activating the PI3K-Akt pathway and promoting calcium uptake

Chen, B. C., Shibu, M. A., Kuo, C. H., Shen, C. Y., Chang-Lee, S. N., Lai, C. H., Chen, R. J., Yao, C. H., Viswanadha, V. P., Liu, J. S., Chen, W. K. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017
2016

Lactobacillus reuteri GMNL-263 reduces hyperlipidaemia and the heart failure process in high-calorie diet-fed induced heart dysfunction in rats

Liao, P. H., Kuo, W. W., Kuo, C. H., Yeh, Y. L., Shen, C. Y., Chen, Y. H., Chen, R. J., Padma, V. V., Chen, Y. H. & Huang, C. Y., Jan 1 2016, In : Journal of Functional Foods. 20, p. 226-235 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017
7 Citations (Scopus)
2019

Blockchain-enabled iWellChain framework integration with the national medical referral system: Development and usability study

Lo, Y. S., Yang, C. Y., Chien, H. F., Chang, S. S., Lu, C. Y. & Chen, R. J., Jan 1 2019, In : Journal of Medical Internet Research. 21, 12, e13563.

Research output: Contribution to journalArticle

Open Access
2018

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

Chen, Y. P., Kuo, W. W., Baskaran, R., Day, C. H., Chen, R. J., Wen, S. Y., Ho, T. J., Padma, V. V., Kuo, C. H. & Huang, C. Y., Apr 1 2018, In : Journal of Cellular Biochemistry. 119, 4, p. 3363-3372 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017
4 Citations (Scopus)
2016
4 Citations (Scopus)
2018

Overexpression of IGF-IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats

Chang, R. L., Nithiyanantham, S., Kuo, W. W., Pai, P. Y., Chang, T. T., Lai, C. H., Chen, R. J., Vijaya Padma, V., Huang, C. Y. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2019

Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats

Lin, K. H., Shibu, M. A., Peramaiyan, R., Chen, Y. F., Shen, C. Y., Hsieh, Y. L., Chen, R. J., Viswanadha, V. P., Kuo, W. W. & Huang, C. Y., Jan 1 2019, In : Journal of Functional Foods. 52, p. 212-218 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Enhancement of beta-catenin in cardiomyocytes suppresses survival protein expression but promotes apoptosis and fibrosis

Lin, J. C., Kuo, W. W., Baskaran, R., Chen, M. C., Ho, T. J., Chen, R. J., Chen, Y. F., Padma, V. V., Lay, I. S. & Huang, C. Y., 2017, In : Cardiology Journal. 24, 2, p. 195-205 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Lessons learned from isolated blunt major pancreatic injury: Surgical experience in one trauma centre

Lin, B. C., Chen, R. J. & Hwang, T. L., Jan 1 2019, In : Injury.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2016
8 Citations (Scopus)
2018

Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs

Feng, C. C., Liao, P. H., Tsai, H. I., Cheng, S. M., Yang, L. Y., PadmaViswanadha, V., Pan, L. F., Chen, R. J., Lo, J. F. & Huang, C. Y., Jan 1 2018, In : International Journal of Medical Sciences. 15, 13, p. 1537-1546 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Inhibition of cardiac hypertrophy effects in d-galactose-induced senescent hearts by alpinate oxyphyllae fructus treatment

Chang, Y. M., Chang, H. H., Lin, H. J., Tsai, C. C., Tsai, C. T., Chang, H. N., Lin, S. L., Padmaviswanadha, V., Chen, R. J. & Huang, C. Y., 2017, In : Evidence-based Complementary and Alternative Medicine. 2017, 2624384.

Research output: Contribution to journalArticle

8 Citations (Scopus)