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Author

  • Joen-Rong Sheu
2013

Effect of Epigallocatechin Gallate on Markers of Inflammation

Geraldine, P., Elango, R., Theodore, J., Sheu, J. R. & Thomas, P. A., 2013, Tea in Health and Disease Prevention. Elsevier Inc., p. 1223-1237 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
2014

Effect of Antrodia camphorata on inflammatory arterial thrombosis-mediated platelet activation: The pivotal role of protein kinase C

Lu, W-J., Lin, S. C., Lan, C. C., Lee, T. Y., Hsia, C. H., Huang, Y. K., Lee, H. C. & Sheu, J. R., 2014, In : Scientific World Journal. 2014, 745802.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2011

A novel role for tamoxifen in the inhibition of human platelets

Chang, Y., Lee, J. J., Chen, W. F., Chou, D. S., Huang, S. Y. & Sheu, J. R., Feb 2011, In : Translational Research. 157, 2, p. 81-91 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Chinese medicines and bioactive compounds for treatment of stroke

Jayakumar, T., Elizebeth, A. R., Yen, T. L. & Sheu, J. R., 2014, In : Chinese Journal of Integrative Medicine. 21, 2, p. 90-101 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hinokitiol is a novel glycoprotein VI antagonist on human platelets

Lu, W-J., Wu, M. P., Lin, K. H., Lin, Y. C., Chou, H. C. & Sheu, J. R., Dec 1 2014, In : Platelets. 25, 8, p. 595-602 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
3 Citations (Scopus)
2015

Salutary effects of cepharanthine against skeletal muscle and kidney injuries following limb ischemia/reperfusion

Kao, M. C., Chung, C. Y., Chang, Y. Y., Lin, C. K., Sheu, J. R. & Huang, C. J., 2015, In : Evidence-based Complementary and Alternative Medicine. 2015, 504061.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Innovative targeting strategies in drug therapy for inflammatory diseases: Mechanistic approaches

Chou, D. S., Sheu, J. R., Thomas, P. A. & Sakthivel, M., 2015, In : Scientific World Journal. 2015, 891676.

Research output: Contribution to journalArticle

Research performance of biomarkers from biofluids in periodontal disease publications

Lin, P. H., Yeh, S. K., Huang, W. C., Chen, H. Y., Chen, C. H., Sheu, J. R., Lin, C. T. & Huang, Y. K., Mar 1 2015, In : Journal of Dental Sciences. 10, 1, p. 61-67 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells

Chuang, Y. F., Yang, H. Y., Ko, T. L., Hsu, Y. F., Sheu, J. R., Ou, G. & Hsu, M. J., Apr 1 2014, In : Biochemical Pharmacology. 88, 3, p. 372-383 12 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Hinokitiol, a tropolone derivative, inhibits mouse melanoma (B16-F10) cell migration and in vivo tumor formation

Huang, C. H., Lu, S. H., Chang, C. C., Thomas, P. A., Jayakumar, T. & Sheu, J. R., Feb 5 2014, In : European Journal of Pharmacology. 746, p. 148-157 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
16 Citations (Scopus)
2013
22 Citations (Scopus)
2012
21 Citations (Scopus)
2011

Baicalein, an active component of Scutellaria baicalensis Georgi, improves cardiac contractile function in endotoxaemic rats via induction of heme oxygenase-1 and suppression of inflammatory responses

Lee, Y. M., Cheng, P. Y., Chim, L. S., Kung, C. W., Ka, S. M., Chung, M. T. & Sheu, J. R., Apr 26 2011, In : Journal of Ethnopharmacology. 135, 1, p. 179-185 7 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2013

Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets

Chang, Y., Huang, S. K. H., Lu, W. J., Chung, C. L., Chen, W. L., Lu, S. H., Lin, K. H. & Sheu, J. R., Jan 25 2013, In : Journal of Biomedical Science. p. 4 1 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2012
56 Citations (Scopus)
2011

p53 in trichostatin A induced C6 glioma cell death

Hsu, Y. F., Sheu, J. R., Hsiao, G., Lin, C-H., Chang, T. H., Chiu, P. T., Wang, C. Y. & Hsu, M. J., May 2011, In : Biochimica et Biophysica Acta - General Subjects. 1810, 5, p. 504-513 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2014
9 Citations (Scopus)
2013

A novel antithrombotic effect of sulforaphane via activation of platelet adenylate cyclase: Ex vivo and in vivo studies

Jayakumar, T., Chen, W. F., Lu, W-J., Chou, D. S., Hsiao, G., Hsu, C-Y., Sheu, J. R. & Hsieh, C. Y., Jun 2013, In : Journal of Nutritional Biochemistry. 24, 6, p. 1086-1095 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2011

Andrographolide enhances nuclear factor-κB subunit p65 Ser 536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells

Hsieh, C. Y., Hsu, M. J., Hsiao, G., Wang, Y. H., Huang, C. W., Chen, S. W., Jayakumar, T., Chiu, P. T., Chiu, Y. H. & Sheu, J. R., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 5942-5955 14 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2014
13 Citations (Scopus)
2015
3 Citations (Scopus)
2013

Cinnamophilin isolated from cinnamomum philippinense protects against collagen degradation in human chondrocytes

Lu, Y. C., Hsiao, G., Lin, K. H., Hsieh, M-S., Jayakumar, T., Wu, T. S. & Sheu, J. R., Jun 2013, In : Phytotherapy Research. 27, 6, p. 892-899 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2011

Traditional Chinese medicine, Xue-Fu-Zhu-Yu decoction, potentiates tissue plasminogen activator against thromboembolic stroke in rats

Lee, J. J., Hsu, W. H., Yen, T. L., Chang, N. C., Luo, Y. J., Hsiao, G. & Sheu, J. R., Apr 12 2011, In : Journal of Ethnopharmacology. 134, 3, p. 824-830 7 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2017

New therapeutic agent against arterial thrombosis: An iridium(III)-derived organometallic compound

Hsia, C. W., Velusamy, M., Tsao, J. T., Hsia, C. H., Chou, D. S., Jayakumar, T., Lee, L. W., Li, J. Y. & Sheu, J. R., Dec 5 2017, In : International Journal of Molecular Sciences. 18, 12, 2616.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Nobiletin, a citrus flavonoid, activates Vasodilator-stimulated phosphoprotein in human platelets through non-cyclic nucleotide-related mechanisms

Jayakumar, T., Lin, K. C., Lu, W-J., Lin, C. Y., Pitchairaj, G., Li, J. Y. & Sheu, J-R., Jan 1 2017, In : International Journal of Molecular Medicine. 39, 1, p. 174-182 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

In vitro antioxidant and anticataractogenic potential of silver nanoparticles biosynthesized using an ethanolic extract of Tabernaemontana divaricata leaves

Anbukkarasi, M., Thomas, P. A., Sheu, J. R. & Geraldine, P., Jul 1 2017, In : Biomedicine and Pharmacotherapy. 91, p. 467-475 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., Feb 6 2017, In : Scientific Reports. 7, 42277.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Prevention of arterial thrombosis by nobiletin: In vitro and in vivo studies

Lu, W-J., Lin, K. C., Liu, C. P., Lin, C. Y., Wu, H. C., Chou, D. S., Geraldine, P., Huang, S. Y., Hsieh, C. Y. & Sheu, J. R., Feb 1 2016, In : Journal of Nutritional Biochemistry. 28, p. 1-8 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2018

Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation

Shyu, R. S., Khamrang, T., Sheu, J. R., Hsia, C. W., Velusamy, M., Hsia, C. H., Chou, D. S. & Chang, C. C., Jan 1 2018, In : Bioinorganic Chemistry and Applications. 2018, p. 8291393 8291393.

Research output: Contribution to journalArticle

2 Citations (Scopus)

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., Nov 14 2018, In : Journal of Clinical Medicine. 7, 11

Research output: Contribution to journalArticle

2016
34 Citations (Scopus)
2018

Mechanisms of TQ-6, a Novel Ruthenium-Derivative Compound, against Lipopolysaccharide-Induced In Vitro Macrophage Activation and Liver Injury in Experimental Mice: The Crucial Role of p38 MAPK and NF-κB Signaling

Hsia, C-H., Velusamy, M., Jayakumar, T., Chen, Y-J., Hsia, C-W., Tsai, J-H., Teng, R-D. & Sheu, J-R., Nov 19 2018, In : Cells. 7, 11

Research output: Contribution to journalArticle

2017

A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies

Hsia, C. H., Velusamy, M., Sheu, J. R., Khamrang, T., Jayakumar, T., Lu, W. J., Lin, K. H. & Chang, C. C., Dec 1 2017, In : Scientific Reports. 7, 1, 9556.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation

Sheu, J. R., Chen, Z. C., Hsu, M. J., Wang, S. H., Jung, K. W., Wu, W. F., Pan, S. H., Teng, R. D., Yang, C. H. & Hsieh, C. Y., Feb 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 2, p. 999-1013 15 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats

Hsu, L. W., Shiao, W. C., Chang, N. C., Yu, M. C., Yen, T. L., Thomas, P. A., Jayakumar, T. & Sheu, J. R., Jan 31 2017, In : Chinese Medicine (United Kingdom). 12, 1, 7.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018
4 Citations (Scopus)

Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation

Shyu, K. G., Velusamy, M., Hsia, C. W., Yang, C. H., Hsia, C. H., Chou, D. S., Jayakumar, T., Sheu, J. R. & Li, J. Y., May 1 2018, In : International Journal of Molecular Medicine. 41, 5, p. 2589-2600 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2019
Open Access
1 Citation (Scopus)
2018
Open Access
2016

The pharmacodynamics of antiplatelet compounds in thrombosis treatment

Jayakumar, T., Yang, C. H., Geraldine, P., Yen, T. L. & Sheu, J. R., Jun 2 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 6, p. 615-632 18 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)
2017
Open Access
2016

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation

Shen, M. Y., Chen, F. Y., Hsu, J. F., Fu, R. H., Chang, C. M., Chang, C. T., Liu, C. H., Wu, J. R., Lee, A. S., Chan, H. C., Sheu, J. R., Lin, S. Z., Shyu, W. C., Sawamura, T., Chang, K. C., Hsu, C. Y. & Chen, C. H., Mar 10 2016, In : Blood. 127, 10, p. 1336-1345 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2013

Novel bioactivity of ellagic acid in inhibiting human platelet activation

Chang, Y., Chen, W. F., Lin, K. H., Hsieh, C. Y., Chou, D. S., Lin, L. J., Sheu, J. R. & Chang, C. C., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 595128.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Hinokitiol, a natural tropolone derivative, offers neuroprotection from thromboembolic stroke in vivo

Jayakumar, T., Hsu, W. H., Yen, T. L., Luo, J. Y., Kuo, Y. C., Fong, T. H. & Sheu, J. R., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 840487.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2015

Sesamol reduces the atherogenicity of electronegative L5 LDL in vivo and in vitro

Chen, W. Y., Chen, F. Y., Lee, A. S., Ting, K. H., Chang, C. M., Hsu, J. F., Lee, W. S., Sheu, J. R., Chen, C. H. & Shen, M. Y., Feb 27 2015, In : Journal of Natural Products. 78, 2, p. 225-233 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2011

Platonin inhibited PDGF-BB-induced proliferation of rat vascular smooth muscle cells via JNK1/2-dependent signaling

Chang, Y., Uen, Y. H., Chen, C. C., Lin, S-C., Tseng, S. Y., Wang, Y. H., Sheu, J. R. & Hsieh, C. Y., Nov 2011, In : Acta Pharmacologica Sinica. 32, 11, p. 1337-1344 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

A novel role of sesamol in inhibiting NF-B-mediated signaling in platelet activation

Chang, C. C., Lu, W-J., Ong, E. T., Chiang, C-W., Lin, S-C., Huang, S. Y. & Sheu, J. R., 2011, In : Journal of Biomedical Science. 18, 1, 93.

Research output: Contribution to journalArticle

31 Citations (Scopus)