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  • Hsing-Jien Kung
2013

Kaposi's Sarcoma-Associated Herpesvirus K-Rta Exhibits SUMO-Targeting Ubiquitin Ligase (STUbL) Like Activity and Is Essential for Viral Reactivation

Izumiya, Y., Kobayashi, K., Kim, K. Y., Pochampalli, M., Izumiya, C., Shevchenko, B., Wang, D. H., Huerta, S. B., Martinez, A., Campbell, M. & Kung, H. J., Aug 1 2013, In : PLoS Pathogens. 9, 8, e1003506.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2019

Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation

Chen, T. J., Wang, H. J., Liu, J. S., Cheng, H. H., Hsu, S. C., Wu, M. C., Lu, C. H., Wu, Y. F., Wu, J. W., Liu, Y. Y., Kung, H. J. & Wang, W. C., Dec 1 2019, In : Communications Biology. 2, 1, 105.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2016

MMP-13 is involved in oral cancer cell metastasis

Huang, S. H., Law, C. H., Kuo, P. H., Hu, R. Y., Yang, C. C., Chung, T. W., Li, J. M., Lin, L. H., Liu, Y. C., Liao, E. C., Tsai, Y. T., Wei, Y. S., Lin, C. C., Chang, C. W., Chou, H. C., Wang, W. C., Chang, M. D. T., Wang, L. H., Kung, H. J., Chan, H. L. & 1 others, Lyu, P. C., Mar 29 2016, In : Oncotarget. 7, 13, p. 17144-17161 18 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2015

Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells

Wen, H. C., Chuu, C. P., Chen, C. Y., Shiah, S. G., Kung, H. J., King, K. L., Su, L. C., Chang, S. C. & Chang, C. H., Apr 1 2015, In : PLoS One. 10, 4, e0125518.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2014

Targeting autophagy overcomes Enzalutamide resistance in castration-resistant prostate cancer cells and improves therapeutic response in a xenograft model

Nguyen, H. G., Yang, J. C., Kung, H. J., Shi, X. B., Tilki, D., Lara, P. N., Devere White, R. W., Gao, A. C. & Evans, C. P., Sep 4 2014, In : Oncogene. 33, 36, p. 4521-4530 10 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)
2019

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

Cai, D., Wang, J., Gao, B., Li, J., Wu, F., Zou, J. X., Xu, J., Jiang, Y., Zou, H., Huang, Z., Borowsky, A. D., Bold, R. J., Lara, P. N., Li, J. J., Chen, X., Lam, K. S., To, K. F., Kung, H. J., Fiehn, O., Zhao, R. & 2 others, Evans, R. M. & Chen, H. W., Dec 1 2019, In : Nature Communications. 10, 1, 4621.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
2011

Histone demethylase JMJD2A regulates Kaposi's sarcoma-associated herpesvirus replication and is targeted by a viral transcriptional factor

Chang, P. C., Fitzgerald, L. D., Hsia, D. A., Izumiya, Y., Wu, C. Y., Hsieh, W. P., Lin, S. F., Campbell, M., Lam, K. S., Luciw, P. A., Tepper, C. G. & Kung, H. J., Apr 1 2011, In : Journal of Virology. 85, 7, p. 3283-3293 11 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2014

A long noncoding RNA connects c-Myc to tumor metabolism

Hung, C. L., Wang, L. Y., Yu, Y. L., Chen, H. W., Srivastava, S., Petrovics, G. & Kung, H. J., Dec 30 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. 18697-18702 6 p.

Research output: Contribution to journalArticle

168 Citations (Scopus)
2012

MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of myc expression in prostate cancer cells

Nadiminty, N., Tummala, R., Lou, W., Zhu, Y., Zhang, J., Chen, X., DeVere White, R. W., Kung, H-J., Evans, C. P. & Gao, A. C., Jan 2012, In : Journal of Biological Chemistry. 287, 2, p. 1527-1537 11 p.

Research output: Contribution to journalArticle

136 Citations (Scopus)
2015

MIR-124 and androgen receptor signaling inhibitors repress prostate cancer growth by downregulating androgen receptor splice variants, EZH2, and Src

Shi, X. B., Ma, A. H., Xue, L., Li, M., Nguyen, H. G., Yang, J. C., Tepper, C. G., Gandour-Edwards, R., Evans, C. P., Kung, H. J. & De Vere White, R. W., Dec 15 2015, In : Cancer Research. 75, 24, p. 5309-5317 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2013

Quantitative analysis of autophagy using advanced 3D fluorescence microscopy

Changou, C. A., Wolfson, D. L., Ahluwalia, B. S., Bold, R. J., Kung, H. J. & Chuang, F. Y. S., Mar 5 2013, In : Journal of Visualized Experiments. 75

Research output: Contribution to journalArticle

4 Citations (Scopus)

Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a marek's disease virus oncoprotein, meq

Subramaniam, S., Johnston, J., Preeyanon, L., Brown, T. C., Kung, H. J. & Cheng, H. H., Aug 1 2013, In : Journal of Virology. 87, 16, p. 9016-9029 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Kaposi's sarcoma-Associated herpesvirus (KSHV) latency-Associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A

Kim, K. Y., Huerta, S. B., Izumiya, C., Wang, D-H., Martinez, A., Shevchenko, B., Kung, H-J., Campbell, M. & Izumiya, Y., Jun 2013, In : Journal of Virology. 87, 12, p. 6782-6793 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2012

Protein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen

Campbell, M., Chang, P. C., Huerta, S., Izumiya, C., Davis, R., Tepper, C. G., Kim, K. Y., Shevchenko, B., Wang, D. H., Jung, J. U., Luciw, P. A., Kung, H. J. & Izumiya, Y., Feb 17 2012, In : Journal of Biological Chemistry. 287, 8, p. 5806-5818 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
2011

Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins

Roy, M., Kung, H-J. & Ghosh, P. M., 2011, In : American Journal of Cancer Research. 1, 4, p. 542-61 20 p.

Research output: Contribution to journalArticle

2015

Tyrosine kinome proiling: Oncogenic mutations and therapeutic targeting in cancer

Ghosh, P., Qiu, Y., Wang, L. Y. & Kung, H. J., Jan 1 2015, Molecular Oncology: Causes of Cancer and Targets for Treatment. Cambridge University Press, p. 58-75 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi's sarcoma associated herpesvirus reactivation

Chang, P. C., Cheng, C. Y., Campbell, M., Yang, Y. C., Hsu, H. W., Chang, T. Y., Chu, C. H., Lee, Y. W., Hung, C. L., Lai, S. M., Tepper, C. G., Hsieh, W. P., Wang, H. W., Tang, C. Y., Wang, W. C. & Kung, H. J., Nov 23 2013, In : BMC Genomics. 14, 1, 824.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2019

Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis

Wang, Y. H., Huang, J. T., Chen, W. L., Wang, R. H., Kao, M. C., Pan, Y. R., Chan, S. H., Tsai, K. W., Kung, H. J., Lin, K. T. & Wang, L. H., Oct 4 2019, In : EMBO Reports. 20, 10, e45986.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Targeting galectin-1 impairs castration-resistant prostate cancer progression and invasion

Shih, T-C., Liu, R., Wu, C-T., Li, X., Xiao, W., Deng, X., Kiss, S., Wang, T., Chen, X-J., Carney, R., Kung, H-J., Duan, Y., Ghosh, P. M. & Lam, K. S., 2018, In : Clinical Cancer Research. 24, 17, p. 4319-4331 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2014

Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor

Guo, W., Liu, R., Bhardwaj, G., Yang, J. C., Changou, C., Ma, A. H., Mazloom, A., Chintapalli, S., Xiao, K., Xiao, W., Kumaresan, P., Sanchez, E., Yeh, C. T., Evans, C. P., Patterson, R., Lam, K. S. & Kung, H. J., Jan 1 2014, In : Cell Death and Disease. 5, 9, e1409.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2018

HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer

Chang, Y. T., Lin, T. P., Tang, J. T., Campbell, M., Luo, Y. L., Lu, S. Y., Yang, C. P., Cheng, T. Y., Chang, C. H., Liu, T. T., Lin, C. H., Kung, H. J., Pan, C. C. & Chang, P. C., Oct 1 2018, In : Cancer Letters. 433, p. 43-52 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2017

REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer

Chang, Y. T., Lin, T. P., Campbell, M., Pan, C. C., Lee, S. H., Lee, H. C., Yang, M. H., Kung, H. J. & Chang, P. C., Mar 3 2017, In : Scientific Reports. 7, 42795.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2016

Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy

Wang, J., Wang, H., Wang, L. Y., Cai, D., Duan, Z., Zhang, Y., Chen, P., Zou, J. X., Xu, J., Chen, X., Kung, H. J. & Chen, H. W., Nov 1 2016, In : Cell Death and Differentiation. 23, 11, p. 1886-1896 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

Non-coding RNAs in castration-resistant prostate cancer: Regulation of androgen receptor signaling and cancer metabolism

Shih, J. W., Wang, L. Y., Hung, C. L., Kung, H. J. & Hsieh, C. L., Dec 4 2015, In : International Journal of Molecular Sciences. 16, 12, p. 28943-28978 36 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)
2020

Signaling in and out: Long-noncoding RNAs in tumor hypoxia

Kuo, T. C., Kung, H. J. & Shih, J. W., May 5 2020, In : Journal of Biomedical Science. 27, 1, 59.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2019

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P. & 3 others, Wang, W. C., Chen, H. W. & Kung, H. J., Jan 3 2019, In : Oncogene. 38, 1, p. 17-32

Research output: Contribution to journalArticle

14 Citations (Scopus)
2014

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism

Wang, H. J., Hsieh, Y. J., Cheng, W. C., Lin, C. P., Lin, Y. S., Yang, S. F., Chen, C. C., Izumiya, Y., Yu, J. S., Kung, H. J. & Wang, W. C., Jan 16 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1, p. 279-284 6 p.

Research output: Contribution to journalArticle

137 Citations (Scopus)
2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Aguirre-Ghiso, J. & 2,688 others, Airoldi, E. M., Airoldi, E. M., Ait-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Awale, S., Azad, N., Bachetti, T., Backer, J. M., Bae, D. H., Bae, J. S., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, S. H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X. Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J. F., Beck, G. R., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P. A., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M. N., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Bénard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Bianchi, M. W., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Böckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouché, M., Bouchecareilh, M., Boucher, M. J., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M. M., Brancolini, C., Braus, G. H., Bravo-San-Pedro, J. M., Bravosan-Pedro, J. M., Bravosan-Pedro, J. M., Bravosan-Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M. A., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bulavin, D. V., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burke, R. E., Burmeister, M., Bütikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A. M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cecconi, F., Cecconi, F., Cederbaum, A. I., Ceña, V., Ceña, V., Cenci, S., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H. J., Chagin, A. S., Chai, C. Y., Chai, C. Y., Chakrabarti, G., Chamilos, G., Chan, E. Y. W., Chan, M. T. V., Chandra, D., Chandra, P., Chang, C. P., Chang, R. C. C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C. J., Chen, G., Chen, G., Chen, G. C., Chen, G., Chen, H., Chen, J. W., Chen, J. K., Chen, J. K., Chen, M., Chen, M., Chen, P., Chen, Q., Chen, Q., Chen, S. D., Chen, S., Chen, S. S. L., Chen, W., Chen, W. J., Chen, W. Q., Chen, W., Chen, X., Chen, Y. H., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y., Chen, Y., Chen, Y. J., Chen, Y. Q., Chen, Y., Chen, Z., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S. G., Chiacchiera, F., Chiang, H. L., Chiarelli, R., Chiariello, M., Chiariello, M., Chiariello, M., Chieppa, M., Chin, L. S., Chiong, M., Chiu, G. N. C., Cho, D. H., Cho, S. G., Cho, W. C., Cho, Y. Y., Cho, Y. S., Choi, A. M. K., Choi, E. J., Choi, E. K., Choi, E. K., Choi, E. K., Choi, E. K., Choi, J., Choi, M. E., Choi, S. I., Choi, S. I., Chou, T. F., Chouaib, S., Choubey, D., Choubey, V., Chow, K. C., Chowdhury, K., Chu, C. T., Chuang, T. H., Chun, T., Chung, H., Chung, T., Chung, Y. L., Chwae, Y. J., Cianfanelli, V., Ciarcia, R., Ciechomska, I. A., Ciriolo, M. R., Cirone, M., Claerhout, S., Claerhout, S., Clague, M. J., Clària, J., Clarke, P. G. H., Clarke, R., Clementi, E., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E. M., Cocco, T., Codogno, P., Coers, J., Cohen, E. E. W., Colecchia, D., Colecchia, D., Colecchia, D., Coletto, L., Coll, N. S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K. L., Coombs, G. H., Cooper, C. D., Cooper, J. M., Coppens, I., Corasaniti, M. T., Corazzari, M., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M. D., Corral-Ramos, C., Corti, O., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S. L., Coto-Montes, A., Cottet, S., Cottet, S., Couve, E., Covey, L. R., Cowart, L. A., Cox, J. S., Coxon, F. P., Coyne, C. B., Cragg, M. S., Craven, R. J., Crepaldi, T., Crespo, J. L., Criollo, A., Crippa, V., Cruz, M. T., Cuervo, A. M., Cuezva, J. M., Cui, T., Cutillas, P. R., Czaja, M. J., Czyzyk-Krzeska, M. F., Dagda, R. K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K. N., Valle, L. D., Dalmasso, G., D'amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V. M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C. R., Davey, H. M., Davids, L. M., Dávila, D., Davis, R. J., Dawson, T. M., Dawson, T. M., Dawson, V. L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, P., de Figueiredo, R. C. B. Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G. R. Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J. P., Decuypere, J. P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D. P., Delage-Mourroux, R., Delbridge, L. M. D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C. J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T. P., Devenish, R. J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., Di Antonio, A., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dickey, C. A., Dickson, R. C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S. P., Ding, C., Ding, W. X., Ding, Z., Dini, L., Distler, J. H. W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R. C. J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X. C., Dong, X., Dong, Z., Donohue, T. M., Donohue-Jr, T. M., Doran, K. S., D'orazi, G., Dorn, G. W., Dosenko, V., Dridi, S., Drucker, L., Du, J., Du, L. L., Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V. K., Duchen, M. R., Duchosal, M. A., Duez, H., Dugail, I., Dumit, V. I., Duncan, M. C., Dunlop, E. A., Dunn, W. A., Dupont, N., Dupuis, L., Dupuis, L., Durán, R. V., Durcan, T. M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C. L., Edinger, A. L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N. T., El-Deiry, W. S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C. J. H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A. M., Engelender, S., Enserink, J. M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J. L., Erman, A., Escalante, R., Eskelinen, E. L., Espert, L., Esteban-Martínez, L., Evans, T. 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2830 Citations (Scopus)
2011

Ligand-independent activation of the arylhydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment

Fujisawa, Y., Li, W., Wu, D., Wong, P., Vogel, C., Dong, B., Kung, H. J. & Matsumura, F., Oct 1 2011, In : Biological Chemistry. 392, 10, p. 897-908 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Novel flavonoids with antiproliferative activities against breast cancer cells

Yao, N., Chen, C. Y., Wu, C. Y., Motonishi, K., Kung, H. J. & Lam, K. S., Jul 14 2011, In : Journal of Medicinal Chemistry. 54, 13, p. 4339-4349 11 p.

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33 Citations (Scopus)
2017

ITK inhibition for the targeted treatment of CTCL

Bustos-Villalobos, I., Bergstrom, J. W., Haigh, N. E., Luna, J. I., Mitra, A., Marusina, A. I., Merleev, A. A., Wang, E. A., Sukhov, A., Sultani, H., Liu, R., Bhardwaj, G., Guo, W., Kung, H. J., Lam, K. S. & Maverakis, E., Jul 1 2017, In : Journal of Dermatological Science. 87, 1, p. 88-91 4 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
2012

Modeling Truncated AR Expression in a Natural Androgen Responsive Environment and Identification of RHOB as a Direct Transcriptional Target

Tsai, H-C., Boucher, D. L., Martinez, A., Tepper, C. G. & Kung, H-J., Nov 2012, In : PLoS One. 7, 11

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells

Lin, H. P., Lin, C. Y., Hsiao, P. H., Wang, H. D., Jiang, S. S., Hsu, J. M., Jim, W. T., Chen, M., Kung, H. J. & Chuu, C. P., Dec 5 2013, In : PLoS One. 8, 12, e82625.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2012

Histone methyltransferase NSD2/MMSET mediates constitutive NF-kb signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop

Yang, P., Guo, L., Duan, Z. J., Tepper, C. G., Xue, L., Chen, X., Kung, H-J., Gao, A. C., Zou, J. X. & Chena, H-W., Aug 2012, In : Molecular and Cellular Biology. 32, 15, p. 3121-3131 11 p.

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72 Citations (Scopus)
2011

Targeting Tyrosine Kinases and Autophagy in Prostate Cancer

Kung, H. J., Feb 1 2011, In : Hormones and Cancer. 2, 1, p. 38-46 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2013

Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells

Shi, X. B., Xue, L., Ma, A. H., Tepper, C. G., Gandour-Edwards, R., Kung, H. J. & Devere White, R. W., Aug 29 2013, In : Oncogene. 32, 35, p. 4130-4138 9 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
2011

MiR-125b promotes growth of prostate cancer xenograft tumor through targeting pro-apoptotic genes

Shi, X. B., Xue, L., Ma, A. H., Tepper, C. G., Kung, H. J. & White, R. W. D., Apr 1 2011, In : Prostate. 71, 5, p. 538-549 12 p.

Research output: Contribution to journalArticle

143 Citations (Scopus)
2016

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes

Wang, J., Duan, Z., Nugent, Z., Zou, J. X., Borowsky, A. D., Zhang, Y., Tepper, C. G., Li, J. J., Fiehn, O., Xu, J., Kung, H. J., Murphy, L. C. & Chen, H. W., Aug 10 2016, In : Cancer Letters. 378, 2, p. 69-79 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2011

Recombinant origin of the retrovirus XMRV

Paprotka, T., Delviks-Frankenberry, K. A., Cingöz, O., Martinez, A., Kung, H. J., Tepper, C. G., Hu, W. S., Fivash, M. J., Coffin, J. M. & Pathak, V. K., Jul 1 2011, In : Science. 333, 6038, p. 97-101 5 p.

Research output: Contribution to journalArticle

198 Citations (Scopus)
2014

Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance

Li, C. F., Fang, F. M., Kung, H. J., Chen, L. T., Wang, J. W., Tsai, J. W., Yu, S. C., Wang, Y. H., Li, S. H. & Huang, H. Y., Jan 1 2014, In : Oncotarget. 5, 22, p. 11428-11441 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2016

Erratum: ROR-γ 3 drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer (Nature Medicine (2016))

Wang, J., Zou, J. X., Xue, X., Cai, D., Zhang, Y., Duan, Z., Xiang, Q., Yang, J. C., Louie, M. C., Borowsky, A. D., Gao, A. C., Evans, C. P., Lam, K. S., Xu, J., Kung, H. J., Evans, R. M., Xu, Y. & Chen, H. W., Jun 7 2016, In : Nature Medicine. 22, 6, 1 p.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Retraction to MMP-13 is involved in oral cancer cell metastasis [Oncotarget., 7, 13 (2016) 17144-61, DOI: 10.18632/oncotarget.7942]

Huang, S. H., Law, C. H., Kuo, P. H., Hu, R. Y., Yang, C. C., Chung, T. W., Li, J. M., Lin, L. H., Liu, Y. C., Liao, E. C., Tsai, Y. T., Wei, Y. S., Lin, C. C., Chang, C. W., Chou, H. C., Wang, W. C., Chang, M. D. T., Wang, L. H., Kung, H. J., Chan, H. L. & 1 others, Lyu, P. C., Jan 1 2016, In : Oncotarget. 7, 30, 1 p.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)
2014

KDM4B as a target for prostate cancer: Structural analysis and selective inhibition by a novel inhibitor

Chu, C. H., Wang, L. Y., Hsu, K. C., Chen, C. C., Cheng, H. H., Wang, S. M., Wu, C. M., Chen, T. J., Li, L. T., Liu, R., Hung, C. L., Yang, J. M., Kung, H. J. & Wang, W. C., Jul 24 2014, In : Journal of Medicinal Chemistry. 57, 14, p. 5975-5985 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2012

Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs

Guo, W., Liu, R., Ono, Y., Ma, A-H., Martinez, A., Sanchez, E., Wang, Y., Huang, W., Mazloom, A., Li, J., Ning, J., Maverakis, E., Lam, K. S. & Kung, H-J., 2012, In : Molecular Pharmacology. 82, 5, p. 938-947 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2016

A viral kinase mimics S6 kinase to enhance cell proliferation

Bhatt, A. P., Wong, J. P., Weinberg, M. S., Host, K. M., Giffin, L. C., Buijnink, J., Van Dijk, E., Izumiya, Y., Kung, H. J., Temple, B. R. S. & Damania, B., Jul 12 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 28, p. 7876-7881 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2014

A lytic viral long noncoding RNA modulates the function of a latent protein

Campbell, M., Kim, K. Y., Chang, P. C., Huerta, S., Shevchenko, B., Wang, D. H., Izumiya, C., Kung, H. J. & Izumiya, Y., Feb 1 2014, In : Journal of Virology. 88, 3, p. 1843-1848 6 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2018

Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis

Lin, H. H., Chung, Y., Cheng, C. T., Ouyang, C., Fu, Y., Kuo, C. Y., Chi, K. K., Sadeghi, M., Chu, P., Kung, H. J., Li, C. F., Limesand, K. H. & Ann, D. K., Sep 2 2018, In : Autophagy. 14, 9, p. 1481-1498 18 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

In vitro SUMOylation assay to study SUMO E3 ligase activity

Yang, W. S., Campbell, M., Kung, H. J. & Chang, P. C., Jan 29 2018, In : Journal of Visualized Experiments. 2018, 131, e56629.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Lin, T. P., Chang, Y. T., Lee, S. Y., Campbell, M., Wang, T. C., Shen, S. H., Chung, H. J., Chang, Y. H., Chiu, A. W., Pan, C. C., Lin, C. H., Chu, C. Y., Kung, H. J., Cheng, C. Y. & Chang, P. C., May 1 2016, In : Oncotarget. 7, 18, p. 26137-26151 15 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity

Kuo, C. Y., Cheng, C. T., Hou, P., Lin, Y. P., Ma, H., Chung, Y., Chi, K., Chen, Y., Li, W., Kung, H. J. & Ann, D. K., Jun 7 2016, In : Oncotarget. 7, 23, p. 34052-34069 18 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)