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Author

  • Paul Chan
2013

Pathologic finding of increased expression of interleukin-17 in the synovial tissue of rheumatoid arthritis patients

Li, N., Wang, J. C., Liang, T. H., Zhu, M. H., Wang, J. Y., Fu, X. L., Zhou, J. R., Zheng, S. G., Chan, P. & Han, J., 2013, In : International Journal of Clinical and Experimental Pathology. 6, 7, p. 1375-1379 5 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2016

Response to the letter "no evidence to support high-intensity statin in Chinese patients with coronary heart disease"

Tomlinson, B., Hu, M., Zhang, Y., Liu, Z. M. & Chan, P., Apr 15 2016, In : International Journal of Cardiology. 209, p. 192-193 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Merit of ginseng in the treatment of heart failure in type 1-like diabetic rats

Tsai, C. C., Chan, P., Chen, L. J., Chang, C. K., Liu, Z. & Lin, J. W., 2014, In : BioMed Research International. 2014, 484161.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015

Parthenolide-induced cytotoxicity in H9c2 cardiomyoblasts involves oxidative stress

Tsai, T. Y., Chan, P., Gong, C. L., Wong, K. L., Su, T. H., Shen, P. C., Leung, Y. M. & Liu, Z. M., Jan 1 2015, In : Acta Cardiologica Sinica. 31, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

Investigational glucagon-like peptide-1 agonists for the treatment of obesity

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Oct 2 2016, In : Expert Opinion on Investigational Drugs. 25, 10, p. 1167-1179 13 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)
2013

Suppression of voltage-gated Na+ channels and neuronal excitability by imperatorin

Wu, K. C., Chen, Y. H., Cheng, K. S., Kuo, Y. H., Yang, C. T., Wong, K. L., Tu, Y. K., Chan, P. & Leung, Y. M., Dec 5 2013, In : European Journal of Pharmacology. 721, 1-3, p. 49-55 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2016

Tanshinone IIA Induces Heme Oxygenase 1 Expression and Inhibits Cyclic Strain-Induced Interleukin 8 Expression in Vascular Endothelial Cells

Zhuang, S., Cheng, T-H., Shih, N. L., Liu, J. C., Chen, J. J., Hong, H. J. & Chan, P., Apr 1 2016, In : American Journal of Chinese Medicine. 44, 2, p. 377-388 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

Suppression of Ca2+ influx in endotoxin-treated mouse cerebral cortex endothelial bEND.3 cells

Tsai, T. Y., Lou, S. L., Wong, K. L., Wang, M. L., Su, T. H., Liu, Z. M., Yeh, L. J., Chan, P., Gong, C. L. & Leung, Y. M., May 15 2015, In : European Journal of Pharmacology. 755, p. 80-87 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2019

An evaluation of pitavastatin for the treatment of hypercholesterolemia

Chan, P., Shao, L., Tomlinson, B., Zhang, Y. & Liu, Z. M., Jan 2 2019, In : Expert Opinion on Pharmacotherapy. 20, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Evaluating the efficacy and safety of atorvastatin + ezetimibe in a fixed-dose combination for the treatment of hypercholesterolemia

Ma, Y. B., Chan, P., Zhang, Y., Tomlinson, B. & Liu, Z., May 24 2019, In : Expert Opinion on Pharmacotherapy. 20, 8, p. 917-928 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

Pathologic diagnosis of spontaneous splenic rupture in systemic lupus erythematosus

Li, N., Wang, J. C., Zhu, M. H., Wang, J. Y., Fu, X. L., Zhou, J. R., Zheng, S. G., Han, J. & Chan, P., 2013, In : International Journal of Clinical and Experimental Pathology. 6, 2, p. 273-280 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Giant coronary artery aneurysm with fistula to the pulmonary artery complicated by frequent ventricular premature contractions

Cao, H., Ye, L., Chan, P., Fan, H. & Liu, Z., Feb 7 2015, In : Medicine (United States). 94, 7, p. e530

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Eicosapentaenoic acid triggers Ca2+ release and Ca2+ influx in mouse cerebral cortex endothelial bEND.3 cells

Wu, K. C., Wong, K. L., Wang, M. L., Shiao, L. R., Leong, I. L., Gong, C. L., Cheng, K. S., Chan, P. & Leung, Y. M., Nov 21 2016, (Accepted/In press) In : Journal of Physiological Sciences. p. 1-9 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Evaluation of the pharmacokinetics, pharmacodynamics and clinical efficacy of empagliflozin for the treatment of type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Feb 1 2017, In : Expert Opinion on Drug Metabolism and Toxicology. 13, 2, p. 211-223 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

Metformin transporter pharmacogenomics: insights into drug disposition—where are we now?

Chan, P., Shao, L., Tomlinson, B., Zhang, Y. & Liu, Z. M., Nov 2 2018, In : Expert Opinion on Drug Metabolism and Toxicology. 14, 11, p. 1149-1159 11 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2012

Tanshinone IIA attenuates cyclic strain-induced endothelin-1 expression in human umbilical vein endothelial cells

Hong, H. J., Hsu, F. L., Tsai, S. C., Lin, C. H., Liu, J. C., Chen, J. J., Cheng, T. H. & Chan, P., Jan 2012, In : Clinical and Experimental Pharmacology and Physiology. 39, 1, p. 63-68 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Tanshinone IIA attenuates H2O2-induced injury in human umbilical vein endothelial cells

Chan, P., Chen, Y. C., Lin, L. J., Cheng, T-H., Anzai, K., Chen, Y. H., Liu, Z. M., Lin, J. G. & Hong, H. J., 2012, In : American Journal of Chinese Medicine. 40, 6, p. 1307-1319 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2019

Lysophosphatidylcholine-induced cytotoxicity and protection by heparin in mouse brain bEND.3 endothelial cells

Tsai, T. Y., Leong, I. L., Cheng, K. S., Shiao, L. R., Su, T. H., Wong, K. L., Chan, P. & Leung, Y. M., Feb 1 2019, In : Fundamental and Clinical Pharmacology. 33, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Antagonism of Ca 2+ -sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells

Chen, C. Y., Hour, M. J., Lin, W. C., Wong, K. L., Shiao, L. R., Cheng, K. S., Chan, P. & Leung, Y. M., Jan 1 2019, In : Naunyn-Schmiedeberg's Archives of Pharmacology.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014
2017

Uncontrolled Hypertension Increases with Age in an Older Community-Dwelling Chinese Population in Shanghai

Peng, S., Shen, T., Liu, J., Tomlinson, B., Sun, H., Chen, X., Chan, P., Kuang, Y., Zheng, L., Wu, H., Ding, X., Qian, D., Shen, Y., Gao, P., Fan, H., Liu, Z. & Zhang, Y., Oct 2017, In : Aging and Disease. 8, 5, p. 558-569 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Evolocumab for the treatment of hypercholesterolemia

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Aug 13 2017, (Accepted/In press) In : Expert Opinion on Biological Therapy. p. 1-15 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Statin responses in chinese patients

Tomlinson, B., Chan, P. & Liu, Z. M., Jan 1 2018, In : Journal of Atherosclerosis and Thrombosis. 25, 2, p. 199-202 4 p.

Research output: Contribution to journalLetter

12 Citations (Scopus)
2019

Cell-Specific Effects of GATA (GATA Zinc Finger Transcription Factor Family)-6 in Vascular Smooth Muscle and Endothelial Cells on Vascular Injury Neointimal Formation

Zhuang, T., Liu, J., Chen, X., Pi, J., Kuang, Y., Wang, Y., Tomlinson, B., Chan, P., Zhang, Q., Li, Y., Yu, Z., Zheng, X., Reilly, M., Morrisey, E., Zhang, L., Liu, Z. & Zhang, Y., May 1 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 5, p. 888-901 14 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Quercetin depletes intracellular Ca2+ stores and blunts ATP-triggered Ca2+ signaling in bEnd.3 endothelial cells

Chen, C. Y., Hour, M. J., Shiao, L. R., Wong, K. L., Leung, Y. M., Chan, P. & So, E. C., Jan 1 2019, (Accepted/In press) In : Fundamental and Clinical Pharmacology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2014

Protection of differentiated neuronal NG108-15 cells from P2X7 receptor-mediated toxicity by taurine

Chao, C. C., Chan, P., Kuo, C. S., Gong, C. L., Cheng, T-H., Liu, Z. M., Shen, P. C., Huang, C. C. & Leung, Y. M., 2014, In : Pharmacological Reports. 66, 4, p. 576-584 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017
2 Citations (Scopus)
2019

Single-pill combinations for hypertension: first line treatment for all?

Shao, L., Chan, P., Tomlinson, B., Zhang, Y. & Liu, Z. M., Jan 2 2019, In : Current Medical Research and Opinion.

Research output: Contribution to journalArticle

Open Access
2017

Liraglutide for weight management: benefits and risks

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Mar 4 2017, In : Current Medical Research and Opinion. 33, 3, p. 537-539 3 p.

Research output: Contribution to journalComment/debate

2015

Pharmacogenetics of cutaneous flushing response to niacin/laropiprant combination in Hong Kong Chinese patients with dyslipidemia

Hu, M., Yang, Y. L., Chan, P. & Tomlinson, B., Aug 1 2015, In : Pharmacogenomics. 16, 12, p. 1387-1397 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2011

Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts

Chan, P., Liu, J. C., Lin, L. J., Chen, P. Y., Cheng, T-H., Lin, J. G. & Hong, H. J., 2011, In : American Journal of Chinese Medicine. 39, 2, p. 381-394 14 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
2016
2018

Prediction of response to lipid-lowering treatments

Tomlinson, B., Chan, P. & Liu, Z-M., Nov 2 2018, 6 ed. 3 p. (Expert Review of Precision Medicine and Drug Development)

Research output: Book/ReportBook

2 Citations (Scopus)
2019

Endothelial Forkhead Box Transcription Factor P1 Regulates Pathological Cardiac Remodeling Through Transforming Growth Factor-β1-Endothelin-1 Signal Pathway

Liu, J., Zhuang, T., Pi, J., Chen, X., Zhang, Q., Li, Y., Wang, H., Shen, Y., Tomlinson, B., Chan, P., Yu, Z., Cheng, Y., Zheng, X., Reilly, M., Morrisey, E., Zhang, L., Liu, Z. & Zhang, Y., Aug 20 2019, In : Circulation. 140, 8, p. 665-680 16 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016

Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese

Fan, H., Li, X., Zheng, L., Chen, X., Lan, Q., Wu, H., Ding, X., Qian, D., Shen, Y., Yu, Z., Fan, L., Chen, M., Tomlinson, B., Chan, P., Zhang, Y. & Liu, Z., Feb 17 2016, In : Scientific Reports. 6, 21521.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2019

Dysfunctional endothelial-derived microparticles promote inflammatory macrophage formation via NF-кB and IL-1β signal pathways

Wang, Y., Liu, J., Chen, X., Sun, H., Peng, S., Kuang, Y., Pi, J., Zhuang, T., Zhang, L., Yu, Z., Tomlinson, B., Chan, P., Chen, Y., Zhang, Y. & Li, Y., Jan 1 2019, In : Journal of Cellular and Molecular Medicine. 23, 1, p. 476-486 11 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2017

Effectiveness of endurance exercise training in patients with coronary artery disease: A meta-analysis of randomised controlled trials

Chen, Y. C., Tsai, J. C., Liou, Y. M. & Chan, P., Jun 1 2017, In : European Journal of Cardiovascular Nursing. 16, 5, p. 397-408 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

Tanshinone IIA prevents doxorubicin-induced cardiomyocyte apoptosis through Akt-dependent pathway

Hong, H. J., Liu, J. C., Chen, P. Y., Chen, J. J., Chan, P. & Cheng, T-H., May 31 2012, In : International Journal of Cardiology. 157, 2, p. 174-179 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2011

Nicorandil inhibits angiotensin-II-induced proliferation of cultured rat cardiac fibroblasts

Liou, J. Y., Hong, H. J., Sung, L-C., Chao, H. H., Chen, P. Y., Cheng, T-H., Chan, P. & Liu, J. C., Apr 2011, In : Pharmacology. 87, 3-4, p. 144-151 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2020

An evaluation of liraglutide including its efficacy and safety for the treatment of obesity

Lin, C. H., Shao, L., Zhang, Y. M., Tu, Y. J., Zhang, Y., Tomlinson, B., Chan, P. & Liu, Z., Feb 11 2020, In : Expert Opinion on Pharmacotherapy. 21, 3, p. 275-285 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2017

A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability

Pi, J., Tao, T., Zhuang, T., Sun, H., Chen, X., Liu, J., Cheng, Y., Yu, Z., Zhu, H. H., Gao, W. Q., Suo, Y., Wei, X., Chan, P., Zheng, X., Tian, Y., Morrisey, E., Zhang, L. & Zhang, Y., Jan 6 2017, In : Circulation Research. 120, 1, p. 85-98 14 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Alirocumab for the treatment of hypercholesterolemia

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Mar 20 2017, (Accepted/In press) In : Expert Opinion on Biological Therapy. p. 1-11 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013
1 Citation (Scopus)
2011

Antihypertension induced by tanshinone IIA isolated from the roots of salvia miltiorrhiza

Cheng, J. T., Chan, P., Liu, I. M., Li, Y. X. & Yu, W. J., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 392627.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2016

The Effect of Photoluminescence of Bioceramic Irradiation on Middle Cerebral Arterial Occlusion in Rats

Zhang, L., Chan, P., Liu, Z. M., Hwang, L-L., Lin, K. C., Chan, W. P., Leung, T-K. & Choy, C-S., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 7230962.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

Perturbation of Akt Signaling, Mitochondrial Potential, and ADP/ATP Ratio in Acidosis-Challenged Rat Cortical Astrocytes

Wu, K. C., Cheng, K. S., Wang, Y. W., Chen, Y. F., Wong, K. L., Su, T. H., Chan, P. & Leung, Y. M., May 1 2017, In : Journal of Cellular Biochemistry. 118, 5, p. 1108-1117

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

An overview of new GLP-1 receptor agonists for type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Feb 1 2016, In : Expert Opinion on Investigational Drugs. 25, 2, p. 145-158 14 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Effects of glucose-lowering drugs on cardiovascular outcomes in patients with type 2 diabetes

Tomlinson, B., Hu, M., Zhang, Y., Chan, P. & Liu, Z. M., Nov 1 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 11, p. 1267-1271 5 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)
2015

Early investigational drugs targeting PPAR-α for the treatment of metabolic disease

Liu, Z. M., Hu, M., Chan, P. & Tomlinson, B., May 1 2015, In : Expert Opinion on Investigational Drugs. 24, 5, p. 611-621 11 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)