Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Hung-Yun Lin
2011

Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system

Lin, H. Y., Landersdorfer, C. B., London, D., Meng, R., Lim, C. U., Lin, C., Lin, S., Tang, H. Y., Brown, D., van Scoy, B., Kulawy, R., Queimado, L., Drusano, G. L., Louie, A., Davis, F. B., Mousa, S. A. & Davis, P. J., Feb 2011, In : PLoS Computational Biology. 7, 2, e1001073.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Inducible COX-2-dependent apoptosis in human ovarian cancer cells

Lin, C., Crawford, D. R., Lin, S., Hwang, J., Sebuyira, A., Meng, R., Westfall, J. E., Tang, H. Y., Lin, S. F., Yu, P. Y., Davis, P. J. & Lin, H. Y., 2011, In : Carcinogenesis. 32, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Identification and functions of the plasma membrane receptor for thyroid hormone analogues.

Lin, H. Y., Cody, V., Davis, F. B., Hercbergs, A. A., Luidens, M. K., Mousa, S. A. & Davis, P. J., Apr 2011, In : Discovery medicine. 11, 59, p. 337-347 11 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Overlapping nongenomic and genomic actions of thyroid hormone and steroids

Davis, P. J., Lin, H. Y., Mousa, S. A., Luidens, M. K., Hercbergs, A. A., Wehling, M. & Davis, F. B., Aug 2011, In : Steroids. 76, 9, p. 829-833 5 p.

Research output: Contribution to journalReview article

41 Citations (Scopus)

Crosstalk between integrin αvβ3 and estrogen receptor-α is involved in thyroid hormone-induced proliferation in human lung carcinoma cells

Meng, R., Tang, H. Y., Westfall, J., London, D., Cao, J. H., Mousa, S. A., Luidens, M., Hercbergs, A., Davis, F. B., Davis, P. J. & Lin, H. Y., Nov 22 2011, In : PLoS One. 6, 11, e27547.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2018

Tetraiodothyroacetic acid (tetrac), integrin αvβ3 and disabling of immune checkpoint defense

Davis, P. J., Mousa, S. A. & Lin, H. Y., Jan 1 2018, In : Future Medicinal Chemistry. 10, 14, p. 1637-1639 3 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)
2014

Recurrence of Differentiated Thyroid Carcinoma During Full TSH Suppression: Is the Tumor Now Thyroid Hormone Dependent?

Davis, P. J., Hercbergs, A., Luidens, M. K. & Lin, H. Y., 2014, In : Hormones and Cancer. 6, 1, p. 7-12 6 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)
2013

Incomplete success of angioinhibitor therapy in cancer: Estimation of contribution of pro-angiogenic activity of patient thyroid hormone

Davis, P. J., Yalcin, M., Lin, H. Y., Tang, H. Y., Hercbergs, A., Leith, J. T., Davis, F. B., Luidens, M. K. & Mousa, S. A., 2013, In : Journal of Cancer Science and Therapy. 5, 12, p. 441-445 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

Thyroid hormone and P-glycoprotein in tumor cells

Davis, P. J., Incerpi, S., Lin, H. Y., Tang, H. Y., Sudha, T. & Mousa, S. A., 2015, In : BioMed Research International. 2015, 168427.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2014

Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis

Davis, P. J., Lin, H. Y., Sudha, T., Yalcin, M., Tang, H. Y., Hercbergs, A., Leith, J. T., Luidens, M. K., Ashur-Fabian, O., Incerpi, S. & Mousa, S. A., 2014, In : OncoTargets and Therapy. 7, p. 1619-1624 6 p.

Research output: Contribution to journalReview article

30 Citations (Scopus)
2013

Small Molecule Hormone or Hormone-Like Ligands of Integrin αVβ3: Implications for Cancer Cell Behavior

Davis, P. J., Mousa, S. A., Cody, V., Tang, H. Y. & Lin, H. Y., Dec 2013, In : Hormones and Cancer. 4, 6, p. 335-342 8 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)
2018

Roles of Resveratrol as Signaling Sensor and Gatekeeper

Shih, Y-J., Chen, Y. R., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H-Y. & Davis, P. J., 2018, Resveratrol: State-of-the-Art Science and Health Applications. World Scientific Publishing Co., p. 115-144

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2013

Tetraiodothyroacetic acid (tetrac), nanotetrac and anti-angiogenesis

Davis, P. J., Davis, F. B., Luidens, M. K., Lin, H. Y. & Mousa, S. A., Nov 1 2013, Angiogenesis Modulations in Health and Disease: Practical Applications of Pro- and Anti-angiogenesis Targets. Springer Netherlands, p. 107-117 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
2016

Actions of l-thyroxine and Nano-diamino-tetrac (Nanotetrac) on PD-L1 in cancer cells

Lin, H. Y., Chin, Y-T., Nana, A. W., Shih, Y-J., Lai, H-Y., Tang, H-Y., Leinung, M., Mousa, S. A. & Davis, P. J., Jan 28 2016, (Accepted/In press) In : Steroids.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2015

Receptor proteins for nongenomic actions of thyroid hormone

Davis, P. J., Leonard, J. L., Lin, H. Y., Incerpi, S., Luidens, M. K., Tang, H. Y. & Mousa, S. A., Jul 1 2015, In : Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 15, 1, p. 94-97 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Modulation of angiogenesis by thyroid hormone and hormone analogues: Implications for cancer management

Mousa, S. A., Lin, H. Y., Tang, H. Y., Hercbergs, A., Luidens, M. K. & Davis, P. J., 2014, In : Angiogenesis. 17, 3, p. 463-469 7 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
2018

Contributions of thyroid hormone to cancer metastasis

Mousa, S. A., Glinsky, G. V., Lin, H. Y., Ashur-Fabian, O., Hercbergs, A., Keating, K. A. & Davis, P. J., Sep 1 2018, In : Biomedicines. 6, 3, 89.

Research output: Contribution to journalReview article

Open Access
13 Citations (Scopus)

Thyroxine inhibits resveratrol-caused apoptosis by PD-L1 in ovarian cancer cells

Chin, Y. T., Wei, P. L., Ho, Y., Nana, A. W., Changou, C. A., Chen, Y. R., Yang, Y. C. SH., Hsieh, M. T., Hercbergs, A., Davis, P. J., Shih, Y. J. & Lin, H. Y., May 1 2018, In : Endocrine-Related Cancer. 25, 5, p. 533-545 13 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2014

Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

Chin, Y. T., Hsieh, M. T., Yang, S. H., Tsai, P. W., Wang, S. H., Wang, C. C., Lee, Y. S., Cheng, G. Y., HuangFu, W. C., London, D., Tang, H. Y., Fu, E., Yen, Y., Liu, L. F., Lin, H. Y. & Davis, P. J., 2014, In : Oncotarget. 5, 24, p. 12891-12907 17 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)
2016

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., 2016, In : Oncotarget. 7, 1, p. 362-373 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015

Mechanisms of dihydrotestosterone action on resveratrolinduced anti-proliferation in breast cancer cells with different ER status

Chin, Y. T., Yang, S. H., Chang, T. C., Changou, C. A., Lai, H. Y., Fu, E., HuangFu, W. C., Davis, P. J., Lin, H. Y. & Liu, L. F., 2015, In : Oncotarget. 6, 34, p. 35866-35879 14 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2017

Correction: Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin [Oncotarget, 7, (2016) (27641-27654)]. DOI:10.18632/oncotarget.8505

Yang, Y. C. S. H., Chin, Y. T., Hsieh, M. T., Lai, H. Y., Ke, C. C., Crawford, D. R., Lee, O. K., Fu, E., Mousa, S. A., Grasso, P., Liu, L. F., Chang, H. Y., Tang, H. Y., Lin, H. Y. & Davis, P. J., 2017, In : Oncotarget. 8, 21, p. 35480 1 p.

Research output: Contribution to journalComment/debate

2018

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nana, A. W., Wu, S. Y., Yang, Y. C. S., Chin, Y. T., Cheng, T. M., Ho, Y., Li, W. S., Liao, Y. M., Chen, Y. R., Shih, Y. J., Liu, Y. R., Pedersen, J., Incerpi, S., Hercbergs, A., Liu, L. F., Whang-Peng, J., Davis, P. J. & Lin, H. Y., Oct 1 2018, In : Hormones and Cancer. 9, 5, p. 349-360 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2015

Lovastatin overcomes gefitinib resistance through TNF-a signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo

Yang, S. H., Lin, H. Y., Chang, V. H. S., Chen, C. C., Liu, Y. R., Wang, J., Zhang, K., Jiang, X. & Yen, Y., 2015, In : Oncotarget. 6, 27, p. 23857-23873 17 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2018

Thyroid Hormone Promotes β-Catenin Activation and Cell Proliferation in Colorectal Cancer

Lee, Y. S., Chin, Y. T., Shih, Y. J., Nana, A. W., Chen, Y. R., Wu, H. C., Yang, Y. C. S. H., Lin, H. Y. & Davis, P. J., Jan 29 2018, (Accepted/In press) In : Hormones and Cancer. p. 1-10 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2017

Leptin OB3 peptide suppresses leptin-induced signaling and progression in ovarian cancer cells

Chin, Y. T., Wang, L. M., Hsieh, M. T., Shih, Y. J., Nana, A. W., Changou, C. A., Yang, Y. C. S. H., Chiu, H. C., Fu, E., Davis, P. J., Tang, H. Y. & Lin, H. Y., Jul 27 2017, In : Journal of Biomedical Science. 24, 1, 51.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2019

Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells

Ho, Y., Wang, S. H., Chen, Y. R., Li, Z. L., Chin, Y. T., Yang, Y. C. S. H., Wu, Y. H., Su, K. W., Chu, H. R., Chiu, H. C., Crawford, D. R., Shih, Y. J., Grasso, P., Tang, H. Y., Lin, H. Y., Davis, P. J., Whang-Peng, J. & Wang, K., Nov 1 2019, In : Food and Chemical Toxicology. 133, p. 110808 110808.

Research output: Contribution to journalArticle

2018

2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside potentiates self-renewal of human dental pulp stem cells via the AMPK/ERK/SIRT1 axis

Lin, C. Y., Chin, Y. T., Kuo, P. J., Lee, H. W., Huang, H. M., Lin, H. Y., Weng, I. T., Hsiung, C. N., Chan, Y. H. & Lee, S. Y., Oct 1 2018, In : International Endodontic Journal. 51, 10, p. 1159-1170 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2019

Resveratrol antagonizes thyroid hormone-induced expression of checkpoint and proliferative genes in oral cancer cells

Lin, C. C., Chin, Y. T., Shih, Y. J., Chen, Y. R., Chung, Y. Y., Lin, C. Y., Hsiung, C. N., Whang-Peng, J., Lee, S. Y., Lin, H. Y., Davis, P. J. & Wang, K., Sep 1 2019, In : Journal of Dental Sciences. 14, 3, p. 255-262 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2016

2,3,5,4′-tetrahydroxystilbene-2-O- β -glucoside isolated from Polygoni Multiflori ameliorates the development of periodontitis

Chin, Y. T., Hsieh, M. T., Lin, C. Y., Kuo, P. J., Yang, Y. C. S. H., Shih, Y. J., Lai, H. Y., Cheng, G. Y., Tang, H. Y., Lee, C. C., Lee, S. Y., Wang, C. C., Lin, H. Y., Fu, E., Whang-Peng, J. & Liu, L. F., 2016, In : Mediators of Inflammation. 2016, 6953459.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2020

2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside promotes the effects of dental pulp stem cells on rebuilding periodontal tissues in experimental periodontal defects

Lin, C. Y., Tsai, M. S., Kuo, P. J., Chin, Y. T., Weng, I. T., Wu, Y., Huang, H. M., Hsiung, C. N., Lin, H. Y. & Lee, S. Y., 2020, (Accepted/In press) In : Journal of Periodontology.

Research output: Contribution to journalArticle

2018

Inhibitory effect of Anoectochilus formosanus extract on hyperglycemia-related PD-L1 expression and cancer proliferation

Ho, Y., Chen, Y. F., Wang, L. H., Hsu, K. Y., Chin, Y. T., Yang, Y. C. S. H., Wang, S. H., Chen, Y. R., Shih, Y. J., Liu, L. F., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H. Y., Liu, H. L. & Lin, S. J., Aug 2 2018, In : Frontiers in Pharmacology. 9, AUG, p. 807 807.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2020

Combined Treatment of Heteronemin and Tetrac Induces Antiproliferation in Oral Cancer Cells

Huang, C. H., Huang, T. Y., Chang, W. J., Pan, Y. S., Chu, H. R., Li, Z. L., Unson, S., Chin, Y. T., Lin, C. Y., Huang, H. M., Hsiung, C. N., Gionfra, F., De Vito, P., Pedersen, J. Z., Incerpi, S., Chen, Y. R., Lee, S. Y., Lin, H. Y., Davis, P. J., Whang-Peng, J. & 1 others, Wang, K., Jul 2 2020, In : Marine Drugs. 18, 7, 348.

Research output: Contribution to journalArticle

Open Access
2019

Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status

Chin, Y-T., He, Z-R., Chen, C-L., Chu, H-C., Ho, Y., Su, P-Y., Yang, Y-C. S. H., Wang, K., Shih, Y-J., Chen, Y-R., Pedersen, J. Z., Incerpi, S., Nana, A. W., Tang, H-Y., Lin, H-Y., Mousa, S. A., Davis, P. J. & Whang-Peng, J., Jan 1 2019, In : Frontiers in Endocrinology. 10, APR, p. 130 130.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2012

Nongenomic regulation by thyroid hormone of plasma membrane ion and small molecule pumps.

Lin, H. Y., Tang, H. Y., Davis, F. B., Mousa, S. A., Incerpi, S., Luidens, M. K., Meng, R. & Davis, P. J., Sep 2012, In : Discovery medicine. 14, 76, p. 199-206 8 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)
2011

Membrane receptor for thyroid hormone: Physiologic and pharmacologic implications

Davis, P. J., Davis, F. B., Mousa, S. A., Luidens, M. K. & Lin, H. Y., Feb 10 2011, In : Annual Review of Pharmacology and Toxicology. 51, p. 99-115 17 p.

Research output: Contribution to journalReview article

129 Citations (Scopus)
2013

Evidence to support testing of resveratrol for efficacy in rheumatoid arthritis

Davis, P. J., Vang, O., Meng, R., Crawford, D., Lai, J. H., Liu, F. C., Tang, H. Y. & Lin, H. Y., Feb 2013, Resveratrol: Sources, Production and Health Benefits. Nova Science Publishers, Inc., p. 275-296 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Molecular basis for certain neuroprotective effects of thyroid hormone

Lin, H-Y., Davis, F. B., Luidens, M. K., Mousa, S. A., Cao, J. H., Zhou, M. & Davis, P. J., 2011, In : Frontiers in Molecular Neuroscience. 4, p. 29

Research output: Contribution to journalReview article

Radiosensitization and production of DNA double-strand breaks in U87MG brain tumor cells induced by tetraiodothyroacetic acid (tetrac)

Hercbergs, A. H., Lin, H. Y., Davis, F. B., Davis, P. J. & Leith, J. T., Jan 15 2011, In : Cell Cycle. 10, 2, p. 352-357 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2012

Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts

Mousa, S. A., Yalcin, M., Bharali, D. J., Meng, R., Tang, H. Y., Lin, H. Y., Davis, F. B. & Davis, P. J., Apr 2012, In : Lung Cancer. 76, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)
2018

Radioresistance of cancer cells, integrin αvβ3 and thyroid hormone

Leith, J. T., Mousa, S. A., Hercbergs, A., Lin, H. Y. & Davis, P. J., Dec 1 2018, In : Oncotarget. 9, 97, p. 37069-37075 7 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)
2012

Integrin-Mediated Actions of Thyroid Hormone Analogues on Tumor Cell Chemosensitivity, Integrin-Growth Factor Receptor Crosstalk and Inflammatory Gene Expression.

Hercbergs, A., Davis, F. B., Lin, H-Y., Luidens, M. K., Meng, R., Ashur-Fabian, O., Mousa, S. A. & Davis, P. J., 2012, In : Cancer and Clinical Oncology . 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

2015

Thyroid hormone and anti-apoptosis in tumor cells

Lin, H. Y., Glinsky, G. V., Mousa, S. A. & Davis, P. J., 2015, In : Oncotarget. 6, 17, p. 14735-14743 9 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Low thyroid hormone levels improve survival in murine model for ocular melanoma

Fabian, I. D., Rosner, M., Fabian, I., Vishnevskia-Dai, V., Zloto, O., Maman, E. S., Cohen, K., Ellis, M., Lin, H. Y., Hercbergs, A., Davis, P. J. & Ashur-Fabian, O., 2015, In : Oncotarget. 6, 13, p. 11038-11046 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Overview of transforming growth factor β superfamily involvement in glioblastoma initiation and progression

Nana, A. W., Yang, P. M. & Lin, H. Y., 2015, In : Asian Pacific Journal of Cancer Prevention. 16, 16, p. 6813-6823 11 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)
2018

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic

Lin, H. Y., Chin, Y. T., Shih, Y. J., Chen, Y. R., Leinung, M., Keating, K. A., Mousa, S. A. & Davis, P. J., Sep 1 2018, In : Oncotarget. 9, 75, p. 34033-34037 5 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2017

Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac

Sudha, T., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H. Y., Davis, P. J. & Mousa, S. A., Feb 15 2017, In : International Journal of Nanomedicine. 12, p. 1305-1315 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2011

Inhibitors of PGHS-2 Transactivator activity

Cao, H., Lin, H-Y., Davis, P. J. & Davis, F. B., 2011

Research output: Patent

2020

Molybdenum doping effects for bismuth vanadate photocatalysts on electrochemical performances using the solution process

Chen, Y. S., Lin, L. Y. & Lin, H. Y., Jan 1 2020, In : International Journal of Hydrogen Energy. 45, 1, p. 667-674 8 p.

Research output: Contribution to journalArticle

Open Access
2018

Demonstration of the receptor site for thyroid hormone on integrin αvβ3

Lin, H. Y., Mousa, S. A. & Davis, P. J., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 61-65 5 p. (Methods in Molecular Biology; vol. 1801).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)