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• A novel machine learning algorithm to automatically predict visual outcomes in intravitreal ranibizumab-treated patients with diabetic macular edema

  Chen, S. C., Chiu, H. W., Chen, C. C., Woung, L. C. & Lo, C. M., Dec 1 2018, In: Journal of Clinical Medicine. 7, 12, 475.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• A novel lung alveolar cell model for exploring volatile biomarkers of particle-induced lung injury

  Chuang, H. C., Tsai, S. W., Shie, R. H., Lu, Y. C., Song, S. R., Huang, S. H., Peng, H. Y. & Yang, H. Y., Dec 1 2020, In: Scientific Reports. 10, 1, 15700.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel low-molecular-weight chitosan/gamma-polyglutamic acid polyplexes for nucleic acid delivery into zebrafish larvae

  Leung, S. W., Cheng, P. C., Chou, C. M., Lin, C., Kuo, Y. C., Lee, Y. L. A., Liu, C. Y., Mi, F. L. & Cheng, C. H., Jan 1 2022, In: International Journal of Biological Macromolecules. 194, p. 384-394 11 p.

  Research output: Contribution to journal › Article › peer-review

• A novel ion-bombarded and plasma-passivated charge storage layer for SONOS-type nonvolatile memory

  Liu, S. H., Yang, W. L., Wu, C. C. & Chao, T. S., 2012, In: IEEE Electron Device Letters. 33, 10, p. 1393-1395 3 p., 6280616.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• A novel in vitro retinal differentiation model by co-culturing adult human bone marrow stem cells with retinal pigmented epithelium cells

  Chiou, S. H., Kao, C. L., Peng, C. H., Chen, S. J., Tarng, Y. W., Ku, H. H., Chen, Y. C., Shyr, Y. M., Liu, R. S., Hsu, C. J., Yang, D. M., Hsu, W-M., Kuo, C. D. & Lee, C. H., Jan 21 2005, In: Biochemical and Biophysical Research Communications. 326, 3, p. 578-585 8 p.

  Research output: Contribution to journal › Article › peer-review
  72 Citations (Scopus)

• A Novel Invadopodia-Specific Marker for Invasive and Pro-Metastatic Cancer Stem Cells

  Huang, S. S., Liao, W. Y., Hsu, C. C., Chan, T. S., Liao, T. Y., Yang, P. M., Chen, L. T., Sung, S. Y. & Tsai, K. K., May 31 2021, In: Frontiers in Oncology. 11, p. 638311 638311.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage

  Wang, M. H., Ibrahim, A. S., Hsiao, G., Tawfik, A. & Al-Shabrawey, M., Jun 2020, In: Prostaglandins and Other Lipid Mediators. 148, 106449.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A novel instrument-independent no-scalpel vasectomy - A comparative study against the standard instrument-dependent no-scalpel vasectomy

  Chen, K. C., Aug 2004, In: International Journal of Andrology. 27, 4, p. 222-227 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• A novel injectable in situ forming gel based on carboxymethyl hexanoyl chitosan/hyaluronic acid polymer blending for sustained release of berberine

  Lu, K. Y., Lin, Y. C., Lu, H. T., Ho, Y. C., Weng, S. C., Tsai, M. L. & Mi, F. L., Feb 15 2019, In: Carbohydrate Polymers. 206, p. 664-673 10 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• A novel injectable chitosan/polyglutamate polyelectrolyte complex hydrogel with hydroxyapatite for soft-tissue augmentation

  Ji, D. Y., Kuo, T. F., Wu, H. D., Yang, J. C. & Lee, S. Y., Aug 1 2012, In: Carbohydrate Polymers. 89, 4, p. 1123-1130 8 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: A phase II double-blind, randomized placebo-controlled study

  Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C. & Lai, Y. L., 2012, In: Clinical and Investigative Medicine. 35, 1

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• A novel indoor heat source distribution surveillance system through sensor network

  Luo, R. C., Hu, C. C., Chen, O. & Huang, S. K., Dec 18 2007, Proceedings of the 2007 IEEE International Conference on Mechatronics and Automation, ICMA 2007. p. 354-359 6 p. 4303568

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  4 Citations (Scopus)

• A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

  Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., Feb 6 2017, In: Scientific Reports. 7, 42277.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A Novel Improved Algorithm for Protein Classification Through a Graph Similarity Approach

  Chou, H. H., Hsu, C. T., Wang, H. C. & Hsieh, S. Y., 2020, Intelligent Computing Theories and Application - 16th International Conference, ICIC 2020, Proceedings. Huang, D-S. & Jo, K-H. (eds.). Springer Science and Business Media Deutschland GmbH, p. 251-261 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12464 LNCS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• A Novel IGLC2 Gene Linked With Prognosis of Triple-Negative Breast Cancer

  Chang, Y. T., Tsai, W. C., Lin, W. Z., Wu, C. C., Yu, J. C., Tseng, V. S., Liao, G. S., Hu, J. M., Hsu, H. M., Chang, Y. J., Lin, M. C., Chu, C. M. & Yang, C. Y., Jan 27 2022, In: Frontiers in Oncology. 11, 759952.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers - The role of histone deacetylase and endoplasmic reticulum stress

  Chen, Y. C., Huang, W. J., Hsu, J. L., Yu, C. C., Wang, W. T. & Guh, J. H., Sep 2013, In: Prostate. 73, 12, p. 1270-1280 11 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

  Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In: Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A novel human stem cell coculture system that maintains the survival and function of culture islet-like cell clusters

  Kuo, C. C., Kuo, F. C., Chen, C. F. & Liu, S. H., 2008, In: Cell Transplantation. 17, 6, p. 657-664 8 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• A novel home appliance control system for people with disabilities

  Chen, W. L., Liou, A. H. A., Chen, S. C., Chung, C. M., Chen, Y. L. & Shih, Y. Y., 2007, In: Disability and Rehabilitation: Assistive Technology. 2, 4, p. 201-206 6 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel HLA-B allele, B*58: 01:12, detected in a Taiwanese volunteer bone marrow stem cell donor using sequence-based typing method

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Aug 1 2013, In: International Journal of Immunogenetics. 40, 4, p. 324-325 2 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• A novel HLA-A2-restricted CTL epitope of tumor-associated antigen L6 can inhibit tumor growth in vivo

  Tu, S. H., Huang, H. I., Lin, S. I., Liu, H. Y., Sher, Y. P., Chiang, S. K., Chong, P., Roffler, S., Tseng, G. C., Chen, H. W. & Liu, S. J., Apr 2012, In: Journal of Immunotherapy. 35, 3, p. 235-244 10 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

  Wu, Y. H., Hong, C. W., Wang, Y. C., Huang, W. J., Yeh, Y. L., Wang, B. J., Wang, Y. J. & Chiu, H. W., Aug 1 2017, In: Cancer Letters. 400, p. 79-88 10 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling

  Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., Jun 2021, In: Biomedicine and Pharmacotherapy. 138, 111485.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes

  Wu, H. T., Ou, H. Y., Hung, H. C., Su, Y. C., Lu, F. H., Wu, J. S., Yang, Y. C., Wu, C. L. & Chang, C. J., Aug 1 2016, In: Diabetologia. 59, 8, p. 1732-1742 11 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• A novel HDAC1/2 inhibitor suppresses colorectal cancer through apoptosis induction and cell cycle regulation

  Lee, H. Y., Tang, D. W., Liu, C. Y. & Cho, E. C., Jan 25 2022, In: Chemico-Biological Interactions. 352, 109778.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel HA/β-TCP-collagen composite enhanced new bone formation for dental extraction socket preservation in beagle dogs

  Ho, K. N., Salamanca, E., Chang, K. C., Shih, T. C., Chang, Y. C., Huang, H. M., Teng, N. C., Lin, C. T., Feng, S-W. & Chang, W. J., Mar 11 2016, In: Materials. 9, 3, 191.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A Novel Grid-based Platform for the Care of Taiwan's Lung Cancer Patients

  Shu-Hui, H., Chung-Chen, T., Shin-Hung, L., Jen-Hsin, C., Huang-Shen, C. & Wen-Te, L., 2008, Proceedings of the 2008 International Conference on Semantic Web and Web Services, SWWS 2008. p. 153-154 2 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• A novel global strain diastolic index correlates with plasma NT-proBNP levels in asymptomatic hypertensive patients with preserved left ventricular ejection fraction

  Chiang, S. J., Daimon, M., Ishii, K., Miyazaki, S., Koiso, Y., Suzuki, H., Miyauchi, K., Yang, B., Yeh, M. H., Hwang, B. & Daida, H., Jun 2012, In: Journal of Echocardiography. 10, 2, p. 56-64 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel generalized item relational structure theory based on Liu’s normalization and consistency criteria

  Liu, H. C., Shia, B. C., Ju, J. M., Wang, T. L., Su, C. H. & Lin, Y. T., 2016, In: ICIC Express Letters. 10, 12, p. 2957-2962 6 p.

  Research output: Contribution to journal › Article › peer-review

• A novel function of the lysophosphatidic acid receptor 3 (LPAR3) gene in zebrafish on modulating anxiety, circadian rhythm locomotor activity, and short-term memory

  Lin, Y. N., Audira, G., Malhotra, N., Anh, N. T. N., Siregar, P., Lu, J. H., Lee, H. & Hsiao, C. D., Apr 2 2020, In: International journal of molecular sciences. 21, 8, 2837.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel fucoidan complex-based functional beverage attenuates oral cancer through inducing apoptosis, G2/M cell cycle arrest and retarding cell migration/invasion

  Chen, P. H., Chiang, P. C., Lo, W. C., Su, C. W., Wu, C. Y., Chan, C. H., Wu, Y. C., Cheng, H. C., Deng, W. P., Lin, H. K. & Peng, B. Y., Oct 2021, In: Journal of Functional Foods. 85, 104665.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel follicle-stimulating hormone-induced Gαh/phospholipase C-δ1 signaling pathway mediating rat Sertoli cell Ca2+-influx

  Lin, Y. F., Tseng, M. J., Hsu, H. L., Wu, Y. W., Lee, Y-H. & Tsai, Y-H., 2006, In: Molecular Endocrinology. 20, 10, p. 2514-2527 14 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist

  Yamaji, S., Saegusa, J., Ieguchi, K., Fujita, M., Mori, S., Takada, Y. K. & Takada, Y., 2010, In: PLoS One. 5, 4, e10273.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• A novel fabrication method for the mold insert of microlens arrays by hot embossing molding

  Shen, Y. K., Dec 2006, In: Polymer Engineering and Science. 46, 12, p. 1797-1803 7 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• A novel fabrication method for mold insert of injection molded microlens array

  Shen, Y. K., 2006, Materials Science Forum. Vol. 532-533. p. 665-668 4 p. (Materials Science Forum; vol. 532-533).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  3 Citations (Scopus)

• A novel fabrication method and optimum tooling design for microlens arrays

  Shen, Y. K., Chang, C. Y., Shen, Y. S. & Yang, S. Y., 2006, Annual Technical Conference - ANTEC, Conference Proceedings. Vol. 5. p. 2571-2575 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  1 Citation (Scopus)

• A novel exon 15-deleted, splicing variant of Slit2 shows potential for growth inhibition in addition to invasion inhibition in lung cancer

  Lin, Y. Y., Yang, C. H., Sheu, G. T., Huang, C. Y. F., Wu, Y. C., Chuang, S. M., Fann, M. J., Chang, H., Lee, H. & Chang, J. T., Aug 1 2011, In: Cancer. 117, 15, p. 3404-3415 12 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• A novel electrospun Microtube Array Membrane (MTAM) based low cost conceptual tubular Microbial Fuel Cell (MFC)

  Chew, C. H., Wu, C. C. & Chen, C. C., Oct 1 2016, In: European Polymer Journal. 83, p. 138-147 10 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A novel electrokinetic micromixer

  Wu, H. Y. & Liu, C. H., Jan 31 2005, In: Sensors and Actuators, A: Physical. 118, 1, p. 107-115 9 p.

  Research output: Contribution to journal › Article › peer-review
  97 Citations (Scopus)

• A novel electrokinetic micromixer

  Wu, H. Y. & Liu, C. H., 2003, TRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers. Institute of Electrical and Electronics Engineers Inc., Vol. 1. p. 631-634 4 p. 1215552

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  8 Citations (Scopus)

• A novel efficient Au-Ag alloy catalyst system: Preparation, activity, and characterization

  Wang, A. Q., Liu, J. H., Lin, S. D., Lin, T. S. & Mou, C. Y., Jul 1 2005, In: Journal of Catalysis. 233, 1, p. 186-197 12 p.

  Research output: Contribution to journal › Article › peer-review
  323 Citations (Scopus)

• A novel earplug system for filtering out dental noise

  Chang, J. R., Cheng, H. K., Lee, S. Y., Bai, M. R. & Lean, R. I., 2003, In: Journal of Marine Science and Technology. 11, 4, p. 179-188 10 p.

  Research output: Contribution to journal › Article › peer-review

• A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo

  Wu, Y. W., Chao, M. W., Tu, H. J., Chen, L. C., Hsu, K. C., Liou, J. P., Yang, C. R., Yen, S. C., HuangFu, W. C. & Pan, S. L., May 2021, In: Oncogenesis. 10, 5, 39.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

  Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In: Frontiers in Pharmacology. 9, MAR, 205.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA

  Yang, D., van Boom, S. S. G. E., Reedijk, J., van Boom, J. H., Farrell, N. & Wang, A. H. J., Jul 1995, In: Nature Structural Biology. 2, 7, p. 577-586 10 p.

  Research output: Contribution to journal › Article › peer-review
  66 Citations (Scopus)

• A novel detection platform for shrimp white spot syndrome virus using an ICP11-dependent immunomagnetic reduction (IMR) assay

  Liu, B. H., Lin, Y. C., Ho, C. S., Yang, C. C., Chang, Y. T., Chang, J. F., Li, C. Y., Cheng, C. S., Huang, J. Y., Lee, Y. F., Hsu, M. H., Lin, F. C., Wang, H. C., Lo, C. F., Yang, S. Y. & Wang, H. C., Sep 18 2015, In: PLoS One. 10, 9, e0138207.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy

  Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., 2015, In: Oncotarget. 6, 15, p. 13671-13687 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• A novel DEMATEL theory based on Liu's polytomous ordering theory

  Liu, H. C., Ou, Y. C., Shia, B. C. & Tsai, H. C., Aug 2 2016, In: Unknown Journal. 71, 01001.

  Research output: Contribution to journal › Article › peer-review

• A novel defensin encoded by a mungbean cDNA exhibits insecticidal activity against bruchid

  Chen, K. C., Lin, C. Y., Kuan, C. C., Sung, H. Y. & Chen, C. S., Dec 4 2002, In: Journal of Agricultural and Food Chemistry. 50, 25, p. 7258-7263 6 p.

  Research output: Contribution to journal › Article › peer-review
  79 Citations (Scopus)

• A novel core fractionation process of human plasma by expanded bed adsorption chromatography

  Lihme, A., Hansen, M. B., Andersen, I. V. & Burnouf, T., Apr 2010, In: Analytical Biochemistry. 399, 1, p. 102-109 8 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)