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• 2021

  Human biomonitoring reference values and characteristics of Phthalate exposure in the general population of Taiwan: Taiwan Environmental Survey for Toxicants 2013–2016

  Liao, K. W., Chang, W. H., Chou, W. C., Huang, H. B., Waits, A., Chen, P. C. & Huang, P. C., Jun 2021, In: International Journal of Hygiene and Environmental Health. 235, 113769.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Human ipsc-derived neurons as a platform for deciphering the mechanisms behind brain aging

  Chao, C. C., Shen, P. W., Tzeng, T. Y., Kung, H. J., Tsai, T. F. & Wong, Y. H., Nov 2021, In: Biomedicines. 9, 11, 1635.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  1 Citation (Scopus)

• Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment

  Nebie, O., Carvalho, K., Barro, L., Delila, L., Faivre, E., Renn, T-Y., Chou, M-L., Wu, Y-W., Niem-Redene, A., Chou, S-Y., Buée, L., Hu, C-J., Peng, C-W., Devos, D., Blum, D. & Burnouf, T., Oct 1 2021, In: Brain. 144, 10, p. 3142-3158 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Human platelet lysates for human cell propagation

  Barro, L., Burnouf, P. A., Chou, M. L., Nebie, O., Wu, Y. W., Chen, M. S., Radosevic, M., Knutson, F. & Burnouf, T., 2021, In: Platelets. 32, 2, p. 152-162 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation

  Yu, D. C. W., Wu, F. C., Wu, C. E., Chow, L. P., Ho, H. N. & Chen, H. F., Jan 2021, In: iScience. 24, 1, 102003.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyaluronic acid supplement as a chondrogenic adjuvant in promoting the therapeutic efficacy of stem cell therapy in cartilage healing

  Wong, C. C., Sheu, S. D., Chung, P. C., Yeh, Y. Y., Chen, C. H., Chang, Y. W. & Kuo, T. F., Mar 2021, In: Pharmaceutics. 13, 3, 432.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Hybrid Surgeons Play a Mainstay Role in the Endovascular Era

  Lee, T. S., Chen, F. C. & Li, S. J., Mar 2021, In: Annals of Thoracic Surgery. 111, 3, p. 1091-1092 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Hybrid ZnO/chitosan antimicrobial coatings with enhanced mechanical and bioactive properties for titanium implants

  Lin, M. H., Wang, Y. H., Kuo, C. H., Ou, S. F., Huang, P. Z., Song, T. Y., Chen, Y. C., Chen, S. T., Wu, C. H., Hsueh, Y. H. & Fan, F. Y., Apr 1 2021, In: Carbohydrate Polymers. 257, 117639.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Hydrogen Bond Strength-Mediated Self-Assembly of Supramolecular Nanogels for Selective and Effective Cancer Treatment

  Ilhami, F. B., Yang, Y. T., Lee, A. W., Chiao, Y. H., Chen, J. K., Lee, D. J., Lai, J. Y. & Cheng, C. C., Oct 11 2021, In: Biomacromolecules. 22, 10, p. 4446-4457 12 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Hydrogen sulfide attenuates aortic remodeling in aortic dissection associating with moderated inflammation and oxidative stress through a NO-dependent pathway

  Lu, H. Y., Hsu, H. L., Li, C. H., Li, S. J., Lin, S. J., Shih, C. M. & Shih, C. C., May 2021, In: Antioxidants. 10, 5, 682.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Hydrolysable tannins exhibit acetylcholinesterase inhibitory and anti-glycation activities in vitro and learning and memory function improvements in scopolamine-induced amnesiac mice

  Chen, L. G., Lin, S. Y., Lee, Y. S., Wang, C. C. & Hou, W. C., Aug 2021, In: Biomedicines. 9, 8, 1066.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hydrothermal Synthesis of Co₃O₄/ZnCo₂O₄Core-Shell Nanostructures for High-Performance Supercapacitors

  Lin, E. S., Chao, F. S., Liang, C. J., Chang, C. J., Fang, A., Lin, C. K., Chang, Y. C., Tsay, C. Y., Wu, J. J. & Chen, C. Y., Dec 2021, In: Journal of the Electrochemical Society. 168, 12, 123502.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Hydroxychloroquine (Hcq) modulates autophagy and oxidative dna damage stress in hepatocellular carcinoma to overcome sorafenib resistance via tlr9/sod1/hsa-mir-30a5p/beclin-1 axis

  Chen, M. Y., Yadav, V. K., Chu, Y. C., Ong, J. R., Huang, T. Y., Lee, K. F., Lee, K. H., Yeh, C. T. & Lee, W. H., Jul 1 2021, In: Cancers. 13, 13, 3227.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Hyperbaric oxygen therapy alleviates the autoimmune encephalomyelitis via the reduction of IL-17a and GM-CSF production of autoreactive T cells as well as boosting the immunosuppressive IL-10 in the central nervous system tissue lesions

  Chiou, H. Y. C., Huang, S. H., Hung, C. H., Tsai, S. M., Kuo, H. R., Huang, Y. R., Wang, J. W., Chen, S. C., Kuo, C. H., Wu, D. C., Huang, S. K., Hsu, S. H. & Lin, M. H., Aug 2021, In: Biomedicines. 9, 8, 943.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyperglycemia-Induced Cardiac Damage Is Alleviated by Heat-Inactivated Lactobacillus reuteri GMNL-263 via Activation of the IGF1R Survival Pathway

  Koay, K. P., Tsai, B. C. K., Kuo, C. H., Kuo, W. W., Luk, H. N., Day, C. H., Chen, R. J., Chen, M. Y. C., Padma, V. V. & Huang, C. Y., Aug 2021, In: Probiotics and Antimicrobial Proteins. 13, 4, p. 1044-1053 10 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Hyperlipidemia Is a Risk Factor of Adhesive Capsulitis: Real-World Evidence Using the Taiwanese National Health Insurance Research Database

  Wang, J. Y., Liaw, C. K., Huang, C. C., Liou, T. H., Lin, H. W. & Huang, S. W., 2021, In: Orthopaedic Journal of Sports Medicine. 9, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

  Lin, H., Huang, Y. S., Fustin, J. M., Doi, M., Chen, H., Lai, H. H., Lin, S. H., Lee, Y. L., King, P. C., Hou, H. S., Chen, H. W., Young, P. Y. & Chao, H. W., Dec 2021, In: Nature Communications. 12, 1, p. 645 645.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Citations (Scopus)

• Hypoxia Induced by Cobalt Chloride Triggers Autophagic Apoptosis of Human and Mouse Drug-Resistant Glioblastoma Cells through Targeting the PI3K-AKT-mTOR Signaling Pathway

  Lee, Y. W., Cherng, Y. G., Yang, S. T., Liu, S. H., Chen, T. L. & Chen, R. M., 2021, In: Oxidative Medicine and Cellular Longevity. 2021, 5558618.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

  Cheng, W. H., Chen, C. L., Chen, J. Y., Lin, C. H. & Chen, B-C., Dec 2021, In: Molecular Medicine. 27, 1, 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Iatrogenic Vocal Fold Paralysis: A Population-Based Cohort Study in Taiwan

  Lai, Y. T., Chao, P. Z., Chang, Y. K., Yen, Y. C., Shen, Y. T., Yu, T. Y., Dailey, S. & Wang, Y. H., 2021, (Accepted/In press) In: Annals of Otology, Rhinology and Laryngology.

  Research output: Contribution to journal › Article › peer-review

• Identification and characterization of L-amino acid oxidase 2 gene in orange-spotted grouper (Epinephelus coioides)

  Leu, J. H., Tsai, C. H., Yang, C. H., Chou, H. Y. & Wang, H. C., Jul 2021, In: Developmental and Comparative Immunology. 120, 104058.

  Research output: Contribution to journal › Article › peer-review

• Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

  Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., Dec 2021, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Identification of cancer hub gene signatures associated with immune-suppressive tumor microenvironment and ovatodiolide as a potential cancer immunotherapeutic agent

  Chen, J. H., Wu, A. T. H., Lawal, B., Tzeng, D. T. W., Lee, J. C., Ho, C. L. & Chao, T. Y., Aug 1 2021, In: Cancers. 13, 15, 3847.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Identification of Differentially Expressed Genes in Different Glioblastoma Regions and Their Association with Cancer Stem Cell Development and Temozolomide Response

  Hsu, J. B-K., Lee, T-Y., Cheng, S-J., Lee, G. A., Chen, Y-C., Le, N. Q. K., Huang, S-W., Kuo, D-P., Li, Y-T., Chang, T-H. & Chen, C-Y., Nov 2021, In: Journal of Personalized Medicine. 11, 11, p. 1047 1047.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Identification of dipeptidyl peptidase (Dpp) family genes in clinical breast cancer patients via an integrated bioinformatics approach

  Choy, T. K., Wang, C. Y., Phan, N. N., Khoa Ta, H. D., Anuraga, G., Liu, Y. H., Wu, Y. F., Lee, K. H., Chuang, J. Y. & Kao, T. J., Jul 2021, In: Diagnostics. 11, 7, 1204.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Identification of Novel CDK9 Inhibitors with Better Inhibitory Activity and Higher Selectivity for Cancer Treatment by an Effective Two-Stage Virtual Screening Strategy

  Chen, S-H., Wang, Y-R., Ho, Y., Lin, S-J. & Liu, H. L., Dec 2021, In: Journal of Biomedical Science and Engineering. 14, 12, p. 371-390 12.

  Research output: Contribution to journal › Article › peer-review

• Identification of potential therapeutic antimicrobial peptides against Acinetobacter baumannii in a mouse model of pneumonia

  Jung, C. J., Liao, Y. D., Hsu, C. C., Huang, T. Y., Chuang, Y. C., Chen, J. W., Kuo, Y. M. & Chia, J. S., Dec 2021, In: Scientific Reports. 11, 1, 7318.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Identified the novel resistant biomarkers for taxane-based therapy for triple-negative breast cancer

  Chou, C. W., Huang, Y. M., Chang, Y. J., Huang, C. Y. & Hung, C. S., 2021, In: International Journal of Medical Sciences. 18, 12, p. 2521-2531 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Identifying GPSM family members as potential biomarkers in breast cancer: A comprehensive bioinformatics analysis

  Dang, H. H., Ta, H. D. K., Nguyen, T. T. T., Anuraga, G., Wang, C. Y., Lee, K. H. & Le, N. Q. K., Sep 2021, In: Biomedicines. 9, 9, 1144.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Identifying prognostic factors and developing accurate outcome predictions for in-hospital cardiac arrest by using artificial neural networks

  Chung, C. C., Chiu, W. T., Huang, Y. H., Chan, L., Hong, C. T. & Chiu, H. W., Jun 15 2021, In: Journal of the Neurological Sciences. 425, 117445.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Identify the Characteristics of Metabolic Syndrome and Non-obese Phenotype: Data Visualization and a Machine Learning Approach

  Yu, C. S., Chang, S. S., Lin, C. H., Lin, Y. J., Wu, J. L. & Chen, R. J., Apr 7 2021, In: Frontiers in Medicine. 8, 626580.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• IGFBP-3 stimulates human osteosarcoma cell migration by upregulating VCAM-1 expression

  Chao, C. C., Lee, W. F., Yang, W. H., Lin, C. Y., Han, C. K., Huang, Y. L., Fong, Y. C., Wu, M. H., Lee, I. T., Tsai, Y. H., Tang, C. H. & Liu, J. F., Jan 15 2021, In: Life Sciences. 265, 118758.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• IHELP: Personalised Health Monitoring and Decision Support Based on Artificial Intelligence and Holistic Health Records

  Manias, G., Op Den Akker, H., Azqueta, A., Burgos, D., Capocchiano, N. D., Crespo, B. L., Dalianis, A., Damiani, A., Filipov, K., Giotis, G., Kalogerini, M., Kostadinov, R., Kranas, P., Kyriazis, D., Lophatananon, A., Malwade, S., Marinos, G., Melillo, F., Mas, V. M., Muir, K. & 10 others, Nieroda, M., De Nigro, A., Pandolfo, C., Patino-Martinez, M., Picioroaga, F., Pnevmatikakis, A., Syed-Abdul, S., Tomson, T., Vicheva, D. & Wajid, U., 2021, 26th IEEE Symposium on Computers and Communications, ISCC 2021. Institute of Electrical and Electronics Engineers Inc., (Proceedings - IEEE Symposium on Computers and Communications; vol. 2021-September).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• IL-18: The Forgotten Cytokine in Dengue Immunopathogenesis

  Nanda, J. D., Ho, T. S., Satria, R. D., Jhan, M. K., Wang, Y. T. & Lin, C. F., 2021, In: Journal of Immunology Research. 2021, 8214656.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Il-8 as a potential therapeutic target for periodontitis and its inhibition by caffeic acid phenethyl ester in vitro

  Huang, Y. K., Tseng, K. F., Tsai, P. H., Wang, J. S., Lee, C. Y. & Shen, M. Y., Apr 1 2021, In: International journal of molecular sciences. 22, 7, 3641.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Imaging features of osteoporotic vs non-osteoporotic compression fractures in the elderly

  Liang, H. H., Wu, S. C., Hsieh, C. & Chan, W. P., Jan 19 2021, Osteoporosis Of The Spine: Asian Perspectives. World Scientific Publishing Co., p. 106-121 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Immediate and lasting effects of aerobic exercise on the actigraphic sleep parameters of female nurses: A randomized controlled trial

  Niu, S. F., Lin, C. J., Chen, P. Y., Fan, Y. C., Huang, H. C. & Chiu, H. Y., Jun 2021, In: Research in Nursing and Health. 44, 3, p. 449-457 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Immobilizing type I collagen via natural cross-linker genipin to enhance the osteogenic responses to titanium implant surface

  Liu, C. F., Chang, K. C., Sun, Y. S., Nguyen, D. T. & Huang, H. H., Nov 2021, In: Journal of Materials Research and Technology. 15, p. 885-900 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Immunization with anti-Tn immunogen in maternal rats protects against hyperoxia-induced kidney injury in newborn offspring

  Chen, C. M., Hwang, J. & Chou, H. C., Feb 2021, In: Pediatric Research. 89, 3, p. 476-482 7 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Immunological aspects of sars-cov-2 infection and the putative beneficial role of vitamin-d

  Peng, M. Y., Liu, W. C., Zheng, J. Q., Lu, C. L., Hou, Y. C., Zheng, C. M., Song, J. Y., Lu, K. C. & Chao, Y. C., May 2 2021, In: International journal of molecular sciences. 22, 10, 5251.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  7 Citations (Scopus)

• Immuno-metabolism: The role of cancer niche in immune checkpoint inhibitor resistance

  Weng, C. Y., Kao, C. X., Chang, T. S. & Huang, Y. H., Feb 1 2021, In: International journal of molecular sciences. 22, 3, p. 1-24 24 p., 1258.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  4 Citations (Scopus)

• Immunosuppressive roles of galectin-1 in the tumor microenvironment

  Huang, Y., Wang, H. C., Zhao, J., Wu, M. H. & Shih, T. C., Oct 2021, In: Biomolecules. 11, 10, 1398.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  1 Citation (Scopus)

• Impact of a Desmoplastic Tumor Microenvironment for Colon Cancer Drug Sensitivity: A Study with 3D Chimeric Tumor Spheroids

  Goudar, V. S., Koduri, M. P., Ta, Y. N. N., Chen, Y., Chu, L. A., Lu, L. S. & Tseng, F. G., 2021, (Accepted/In press) In: ACS Applied Materials and Interfaces. 13, 41, p. 48478-48491 14 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Impact of atopic dermatitis on work and activity impairment in Taiwan

  Chan, T. C., Lin, Y. C., Cho, Y. T., Tang, C. H. & Chu, C. Y., Sep 2021, In: Acta Dermato-Venereologica. 101, 9, adv00556.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Impact of chronic obstruction pulmonary disease on survival in patients with advanced stage lung squamous cell carcinoma undergoing concurrent chemoradiotherapy

  Chiu, K. C., Lin, W. C., Chang, C. L. & Wu, S. Y., Jul 1 2021, In: Cancers. 13, 13, 3231.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Impact of Comorbidities on Beneficial Effect of Lactated Ringers vs. Saline in Sepsis Patients

  Tseng, C. H., Chen, T. T., Chan, M. C., Chen, K. Y., Wu, S. M., Shih, M. C. & Tu, Y. K., Dec 13 2021, In: Frontiers in Medicine. 8, 758902.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Impact of COVID-19 pandemic on accessibility of taiwanese medical care

  Jeng, Y., Chen, F. H., Jen, G. H. H., Chen, H. C., Yen, M-F., Chen, C. D., Kuo, H. W., Wang, S. T. & Hsu, C. Y., Sep 2021, In: American Journal of Managed Care. 27, 9, p. E330-E335

  Research output: Contribution to journal › Article › peer-review

• Impact of dialysis modality on major adverse cardiovascular events and all-cause mortality: a national population-based study

  Hu, P. J., Chen, Y. W., Chen, T. T., Sung, L. C., Wu, M. Y. & Wu, M. S., Apr 26 2021, In: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 36, 5, p. 901-908 8 p.

  Research output: Contribution to journal › Article › peer-review

• Impact of DSMES app interventions on medication adherence in type 2 diabetes mellitus: Systematic review and meta-analysis

  Enricho Nkhoma, D., Jenya Soko, C., Joseph Banda, K., Greenfield, D., Li, Y. C. & Iqbal, U., Apr 2021, In: BMJ Health and Care Informatics. 28, 1, e100291.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  2 Citations (Scopus)

• Impact of physiological noise in characterizing the functional MRI default-mode network in Alzheimer’s disease

  Li, Y. T., Chang, C. Y., Hsu, Y. C., Fuh, J. L., Kuo, W. J., Yeh, J. N. T. & Lin, F. H., Jan 2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 1, p. 166-181 16 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)