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• A novel multiprotein bridging factor 1-like protein induces cyst wall protein gene expression and cyst differentiation in giardia lamblia

  Huang, S. W., Lin, Z. Q., Tung, S. Y., Su, L. H., Ho, C. C., Lee, G. A. & Sun, C. H., Feb 1 2021, In: International journal of molecular sciences. 22, 3, p. 1-25 25 p., 1370.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human β1 integrin (CD29)

  Lévesque, J. P., Takada, Y., Puzon-McLaughlin, W. & Simmons, P. J., 2002, In: Hybridoma and Hybridomics. 21, 4, p. 253-260 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma

  Peng, C. H., Liao, C. T., Peng, S. C., Chen, Y. J., Cheng, A. J., Juang, J. L., Tsai, C. Y., Chen, T. C., Chuang, Y. J., Tang, C. Y., Hsieh, W. P. & Yen, T. C., 2011, In: PLoS ONE. 6, 8, e23452.

  Research output: Contribution to journal › Article › peer-review
  137 Citations (Scopus)

• A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

  Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., Feb 1 2018, In: Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel microtubule-disrupting agent induces endoplasmic reticular stress-mediated cell death in human hepatocellular carcinoma cells

  Ho, C. T., Chang, Y. J., Yang, L. X., Wei, P. L., Liu, T. Z. & Liu, J. J., Sep 10 2015, In: PLoS One. 10, 9, e0136340.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• A novel microchip technique for quickly identifying nanogranules in an aqueous solution by transmission electron microscopy: Imaging of platelet granules

  Trang, N. T. T., Chang, J., Chen, W. A., Chen, C. C., Chen, H. M., Chang, C. C. & Fong, T. H., Jul 2020, In: Applied Sciences (Switzerland). 10, 14, 4946.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel micelle-forming material used for preparing a theranostic vehicle exhibiting enhanced in vivo therapeutic efficacy

  Chen, H. P., Chen, M. H., Tung, F. I. & Liu, T. Y., May 14 2015, In: Journal of Medicinal Chemistry. 58, 9, p. 3704-3719 16 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• A novel method to retrieve alerts from a homegrown Computerized Physician Order Entry (CPOE) system of an academic medical center: Comprehensive alert characteristic analysis

  Chien, S. C., Chin, Y. P. H., Yoon, C. H., Islam, M. M., Jian, W. S., Hsu, C. K., Chen, C. Y., Chien, P. H. & Li, Y. C. J., Feb 2021, In: PLoS ONE. 16, 2 February, e0246597.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A novel method of supporting gold nanoparticles on MWCNTs: Synchrotron X-ray reduction

  Lin, K. N., Yang, T. Y., Lin, H. M., Hwu, Y. K., Wu, S. H. & Lin, C. K., Jun 2007, In: China Particuology. 5, 3, p. 237-241 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A novel method of determining the aggregation behavior of microemulsion droplets

  Chen, W. Y., Kuo, C. S. & Liu, D. Z., 2000, In: Progress in Biotechnology. 16, C, p. 137-141 5 p.

  Research output: Contribution to journal › Article › peer-review

• A novel method for the formation of bioceramic nano-calcium hydroxyapatite coatings using sol-gel and dissolution-precipitation processing

  Karalkevičienė, R., Briedytė, G., Murauskas, T., Norkus, M., Žarkov, A., Yang, J. C. & Kareiva, A., 2022, In: Chemija. 33, 2, p. 27-34 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel method for prediction of long-term outcome of women with T1a, T1b, and 10-14 mm invasive breast cancers: A prospective study

  Tabár, L., Chen, H. H., Duffy, S. W., Yen, M. F., Chiang, C. F., Dean, P. B. & Smith, R. A., Feb 5 2000, In: The Lancet. 355, 9202, p. 429-433 5 p.

  Research output: Contribution to journal › Article › peer-review
  145 Citations (Scopus)

• A Novel Method for Locating a Magnetic-Assisted Capsule Endoscope System

  Yen, S. Y., Huang, H. E., Chen, H. C., Huang, F. W., Suk, F. M., Lien, G. S. & Liu, C. W., Oct 2020, In: IEEE Transactions on Magnetics. 56, 10, 9163382.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel method for inferring RFID tag reader recordings into clinical events

  Chang, Y. T., Syed-Abdul, S., Tsai, C. Y. & Li, Y. C., Dec 2011, In: International Journal of Medical Informatics. 80, 12, p. 872-880 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• A novel mechanism underlies the hepatotoxicity of pyrazinamide

  Shih, T. Y., Pai, C. Y., Yang, P., Chang, W. L., Wang, N. C. & Hu, O. Y. P., Apr 1 2013, In: Antimicrobial Agents and Chemotherapy. 57, 4, p. 1685-1690 6 p.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• A novel mechanism involved in TLR4 expression during inflammation

  Li, C. Y. & Lin, F. Y., Jun 2007, In: Acta Anaesthesiologica Taiwanica. 45, 2, p. 63-64 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel mechanism for decreasing plasma lipid level from imidazoline I-1 receptor activation in high fat diet-fed mice

  Niu, C. S., Wu, H. T., Cheng, K. C., Lin, K. C., Chen, C. T. & Cheng, J. T., Apr 13 2011, In: Hormone and Metabolic Research. 43, 7, p. 458-463 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A novel mapping technique to identify focal nonsustained atrial tachycardia: A case report of self-reference mapping technique

  Chin, C. G., Lin, C. Y., Chang, S. L. & Chen, S. A., Apr 2019, In: Journal of Cardiovascular Electrophysiology. 30, 4, p. 618-619 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• A novel machine learning algorithm to automatically predict visual outcomes in intravitreal ranibizumab-treated patients with diabetic macular edema

  Chen, S. C., Chiu, H. W., Chen, C. C., Woung, L. C. & Lo, C. M., Dec 1 2018, In: Journal of Clinical Medicine. 7, 12, 475.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Citations (Scopus)

• A novel lung alveolar cell model for exploring volatile biomarkers of particle-induced lung injury

  Chuang, H. C., Tsai, S. W., Shie, R. H., Lu, Y. C., Song, S. R., Huang, S. H., Peng, H. Y. & Yang, H. Y., Dec 1 2020, In: Scientific Reports. 10, 1, 15700.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A novel low-molecular-weight chitosan/gamma-polyglutamic acid polyplexes for nucleic acid delivery into zebrafish larvae

  Leung, S. W., Cheng, P. C., Chou, C. M., Lin, C., Kuo, Y. C., Lee, Y. L. A., Liu, C. Y., Mi, F. L. & Cheng, C. H., Jan 1 2022, In: International Journal of Biological Macromolecules. 194, p. 384-394 11 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A novel ion-bombarded and plasma-passivated charge storage layer for SONOS-type nonvolatile memory

  Liu, S. H., Yang, W. L., Wu, C. C. & Chao, T. S., 2012, In: IEEE Electron Device Letters. 33, 10, p. 1393-1395 3 p., 6280616.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• A novel in vitro retinal differentiation model by co-culturing adult human bone marrow stem cells with retinal pigmented epithelium cells

  Chiou, S. H., Kao, C. L., Peng, C. H., Chen, S. J., Tarng, Y. W., Ku, H. H., Chen, Y. C., Shyr, Y. M., Liu, R. S., Hsu, C. J., Yang, D. M., Hsu, W-M., Kuo, C. D. & Lee, C. H., Jan 21 2005, In: Biochemical and Biophysical Research Communications. 326, 3, p. 578-585 8 p.

  Research output: Contribution to journal › Article › peer-review
  74 Citations (Scopus)

• A Novel Invadopodia-Specific Marker for Invasive and Pro-Metastatic Cancer Stem Cells

  Huang, S. S., Liao, W. Y., Hsu, C. C., Chan, T. S., Liao, T. Y., Yang, P. M., Chen, L. T., Sung, S. Y. & Tsai, K. K., May 31 2021, In: Frontiers in Oncology. 11, p. 638311 638311.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage

  Wang, M. H., Ibrahim, A. S., Hsiao, G., Tawfik, A. & Al-Shabrawey, M., Jun 2020, In: Prostaglandins and Other Lipid Mediators. 148, 106449.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel instrument-independent no-scalpel vasectomy - A comparative study against the standard instrument-dependent no-scalpel vasectomy

  Chen, K. C., Aug 2004, In: International Journal of Andrology. 27, 4, p. 222-227 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• A novel injectable in situ forming gel based on carboxymethyl hexanoyl chitosan/hyaluronic acid polymer blending for sustained release of berberine

  Lu, K. Y., Lin, Y. C., Lu, H. T., Ho, Y. C., Weng, S. C., Tsai, M. L. & Mi, F. L., Feb 15 2019, In: Carbohydrate Polymers. 206, p. 664-673 10 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• A novel injectable chitosan/polyglutamate polyelectrolyte complex hydrogel with hydroxyapatite for soft-tissue augmentation

  Ji, D. Y., Kuo, T. F., Wu, H. D., Yang, J. C. & Lee, S. Y., Aug 1 2012, In: Carbohydrate Polymers. 89, 4, p. 1123-1130 8 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: A phase II double-blind, randomized placebo-controlled study

  Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C. & Lai, Y. L., 2012, In: Clinical and Investigative Medicine. 35, 1

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• A novel indoor heat source distribution surveillance system through sensor network

  Luo, R. C., Hu, C. C., Chen, O. & Huang, S. K., Dec 18 2007, Proceedings of the 2007 IEEE International Conference on Mechatronics and Automation, ICMA 2007. p. 354-359 6 p. 4303568

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  4 Citations (Scopus)

• A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice

  Sheu, J. R., Chen, Z. C., Jayakumar, T., Chou, D. S., Yen, T. L., Lee, H. N., Pan, S. H., Hsia, C. H., Yang, C. H. & Hsieh, C. Y., Feb 6 2017, In: Scientific Reports. 7, 42277.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A Novel Improved Algorithm for Protein Classification Through a Graph Similarity Approach

  Chou, H. H., Hsu, C. T., Wang, H. C. & Hsieh, S. Y., 2020, Intelligent Computing Theories and Application - 16th International Conference, ICIC 2020, Proceedings. Huang, D-S. & Jo, K-H. (eds.). Springer Science and Business Media Deutschland GmbH, p. 251-261 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12464 LNCS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• A Novel IGLC2 Gene Linked With Prognosis of Triple-Negative Breast Cancer

  Chang, Y. T., Tsai, W. C., Lin, W. Z., Wu, C. C., Yu, J. C., Tseng, V. S., Liao, G. S., Hu, J. M., Hsu, H. M., Chang, Y. J., Lin, M. C., Chu, C. M. & Yang, C. Y., Jan 27 2022, In: Frontiers in Oncology. 11, 759952.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers - The role of histone deacetylase and endoplasmic reticulum stress

  Chen, Y. C., Huang, W. J., Hsu, J. L., Yu, C. C., Wang, W. T. & Guh, J. H., Sep 2013, In: Prostate. 73, 12, p. 1270-1280 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

  Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In: Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A novel human stem cell coculture system that maintains the survival and function of culture islet-like cell clusters

  Kuo, C. C., Kuo, F. C., Chen, C. F. & Liu, S. H., 2008, In: Cell Transplantation. 17, 6, p. 657-664 8 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• A novel home appliance control system for people with disabilities

  Chen, W. L., Liou, A. H. A., Chen, S. C., Chung, C. M., Chen, Y. L. & Shih, Y. Y., 2007, In: Disability and Rehabilitation: Assistive Technology. 2, 4, p. 201-206 6 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A novel HLA-B allele, B*58: 01:12, detected in a Taiwanese volunteer bone marrow stem cell donor using sequence-based typing method

  Yang, K. L., Lee, S. K., Kao, R. H., Lin, C. L. & Lin, P. Y., Aug 1 2013, In: International Journal of Immunogenetics. 40, 4, p. 324-325 2 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• A novel HLA-A2-restricted CTL epitope of tumor-associated antigen L6 can inhibit tumor growth in vivo

  Tu, S. H., Huang, H. I., Lin, S. I., Liu, H. Y., Sher, Y. P., Chiang, S. K., Chong, P., Roffler, S., Tseng, G. C., Chen, H. W. & Liu, S. J., Apr 2012, In: Journal of Immunotherapy. 35, 3, p. 235-244 10 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

  Wu, Y. H., Hong, C. W., Wang, Y. C., Huang, W. J., Yeh, Y. L., Wang, B. J., Wang, Y. J. & Chiu, H. W., Aug 1 2017, In: Cancer Letters. 400, p. 79-88 10 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling

  Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., Jun 2021, In: Biomedicine and Pharmacotherapy. 138, 111485.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes

  Wu, H. T., Ou, H. Y., Hung, H. C., Su, Y. C., Lu, F. H., Wu, J. S., Yang, Y. C., Wu, C. L. & Chang, C. J., Aug 1 2016, In: Diabetologia. 59, 8, p. 1732-1742 11 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• A novel HDAC1/2 inhibitor suppresses colorectal cancer through apoptosis induction and cell cycle regulation

  Lee, H. Y., Tang, D. W., Liu, C. Y. & Cho, E. C., Jan 25 2022, In: Chemico-Biological Interactions. 352, 109778.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A novel HA/β-TCP-collagen composite enhanced new bone formation for dental extraction socket preservation in beagle dogs

  Ho, K. N., Salamanca, E., Chang, K. C., Shih, T. C., Chang, Y. C., Huang, H. M., Teng, N. C., Lin, C. T., Feng, S-W. & Chang, W. J., Mar 11 2016, In: Materials. 9, 3, 191.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• A Novel Grid-based Platform for the Care of Taiwan's Lung Cancer Patients

  Shu-Hui, H., Chung-Chen, T., Shin-Hung, L., Jen-Hsin, C., Huang-Shen, C. & Wen-Te, L., 2008, Proceedings of the 2008 International Conference on Semantic Web and Web Services, SWWS 2008. p. 153-154 2 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• A novel global strain diastolic index correlates with plasma NT-proBNP levels in asymptomatic hypertensive patients with preserved left ventricular ejection fraction

  Chiang, S. J., Daimon, M., Ishii, K., Miyazaki, S., Koiso, Y., Suzuki, H., Miyauchi, K., Yang, B., Yeh, M. H., Hwang, B. & Daida, H., Jun 2012, In: Journal of Echocardiography. 10, 2, p. 56-64 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A novel generalized item relational structure theory based on Liu’s normalization and consistency criteria

  Liu, H. C., Shia, B. C., Ju, J. M., Wang, T. L., Su, C. H. & Lin, Y. T., 2016, In: ICIC Express Letters. 10, 12, p. 2957-2962 6 p.

  Research output: Contribution to journal › Article › peer-review

• A novel function of the lysophosphatidic acid receptor 3 (LPAR3) gene in zebrafish on modulating anxiety, circadian rhythm locomotor activity, and short-term memory

  Lin, Y. N., Audira, G., Malhotra, N., Anh, N. T. N., Siregar, P., Lu, J. H., Lee, H. & Hsiao, C. D., Apr 2 2020, In: International journal of molecular sciences. 21, 8, 2837.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• A novel fucoidan complex-based functional beverage attenuates oral cancer through inducing apoptosis, G2/M cell cycle arrest and retarding cell migration/invasion

  Chen, P. H., Chiang, P. C., Lo, W. C., Su, C. W., Wu, C. Y., Chan, C. H., Wu, Y. C., Cheng, H. C., Deng, W. P., Lin, H. K. & Peng, B. Y., Oct 2021, In: Journal of Functional Foods. 85, 104665.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• A novel follicle-stimulating hormone-induced Gαh/phospholipase C-δ1 signaling pathway mediating rat Sertoli cell Ca2+-influx

  Lin, Y. F., Tseng, M. J., Hsu, H. L., Wu, Y. W., Lee, Y-H. & Tsai, Y-H., 2006, In: Molecular Endocrinology. 20, 10, p. 2514-2527 14 p.

  Research output: Contribution to journal › Article › peer-review
  41 Citations (Scopus)