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• 2016

  CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing

  Clark, A. J., Wiley, D. T., Zuckerman, J. E., Webster, P., Chao, J., Lin, J., Yen, Y. & Davis, M. E., Apr 5 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 14, p. 3850-3854 5 p.

  Research output: Contribution to journal › Article › peer-review
  124 Citations (Scopus)

• CRP/IL-6/IL-10 Single-Nucleotide Polymorphisms Correlate with the Susceptibility and Severity of Community-Acquired Pneumonia

  Chou, S. C., Ko, H. W. & Lin, Y-C., Dec 1 2016, In: Genetic Testing and Molecular Biomarkers. 20, 12, p. 732-740 9 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Cryptococcal meningitis complicated with a large abdominal cyst mimicking acute pancreatitis

  Lee, C. H., Liao, K. H., Lin, H. Y., Lui, T. N., Ou, T. Y. & Lee, W. S., 2016, In: Journal of Microbiology, Immunology and Infection.

  Research output: Contribution to journal › Letter › peer-review
  2 Citations (Scopus)

• Crystal structure of vespid phospholipase A₁ reveals insights into the mechanism for cause of membrane dysfunction

  Hou, M. H., Chuang, C. Y., Ko, T. P., Hu, N. J., Chou, C. C., Shih, Y. P., Ho, C. L. & Wang, A. H. J., Jan 1 2016, In: Insect Biochemistry and Molecular Biology. 68, p. 79-88 10 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells

  Lee, W. R., Shen, S. C., Wu, P. R., Chou, C. L., Shih, Y. H., Yeh, C. M., Yeh, K. T. & Jiang, M. C., Nov 2016, In: Molecular Carcinogenesis.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Cul 3-KLHL20 ubiquitin ligase: Physiological functions, stress responses, and disease implications

  Chen, H. Y., Liu, C. C. & Chen, R. H., 2016, In: Cell Division. 11, 1, 5.

  Research output: Contribution to journal › Review article › peer-review
  12 Citations (Scopus)

• Cullin 3 ubiquitin ligases in cancer biology: Functions and therapeutic implications

  Chen, H. Y. & Chen, R. H., 2016, In: Frontiers in Oncology. 6, MAY, 113.

  Research output: Contribution to journal › Review article › peer-review
  54 Citations (Scopus)

• Cultural adaptation and validation of the Chinese version of the Fatigue Severity Scale in patients with major depressive disorder and nondepressive people

  Wang, M. Y., Liu, I-C., Chiu, C. H. & Tsai, P-S., Jan 1 2016, In: Quality of Life Research. 25, 1, p. 89-99

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Cumulative arsenic exposure is associated with fungal infections: Two cohort studies based on southwestern and northeastern basins in Taiwan

  Hsu, L. I., Cheng, Y. W., Chen, C. J., Wu, M-M., Hsu, K. H., Chiou, H. Y. & Lee, C. H., Nov 1 2016, In: Environment international. 96, p. 173-179 7 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Curative-Intent Aggressive Treatment Improves Survival in Elderly Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma and High Comorbidity Index

  Chen, J. H., Yen, Y. C., Yang, H. C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F. P., Lin, K. C., Lai, M. T., Wu, C. C., Chen, T. M., Chang, C. L., Chow, J. M., Ding, Y. F. & Wu, S. Y., Apr 1 2016, In: Medicine (United States). 95, 14, e3268.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Current methods to manufacture human platelet lysates for cell therapy and tissue engineering: possible trends in product safety and standardization

  Chou, M. L. & Burnouf, T. P. R., Nov 15 2016, In: Vox Sanguinis. 12, p. 168-175

  Research output: Contribution to journal › Review article › peer-review

• Current status and new developments in the production of plasma derivatives

  Burnouf, T. P. R., Jun 28 2016, In: Vox Sanguinis. 11, p. 18-25

  Research output: Contribution to journal › Review article › peer-review

• Current status of personalized medicine based on pharmacogenetics in cardiovascular medicine

  Tomlinson, B., Hu, M., Waye, M. M. Y., Chan, P. & Liu, Z. M., Jan 2 2016, In: Expert Review of Precision Medicine and Drug Development. 1, 1, p. 5-8 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Citation (Scopus)

• Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer: Results from a Six-Year Study Conducted by the Taiwan Endoscopic Breast Surgery Cooperative Group

  Lai, H. W., Chen, S. T., Chen, D. R., Chen, S. L., Chang, T. W., Kuo, S. J., Kuo, Y. L. & Hung, C. S., Mar 2016, In: PLoS ONE. 11, 3, e0150310.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• CXCL5 signaling is a shared pathway of neuroinflammation and blood-brain barrier injury contributing to white matter injury in the immature brain

  Wang, L. Y., Tu, Y. F., Lin, Y. C. & Huang, C. C., Jan 6 2016, In: Journal of Neuroinflammation. 13, 1, 6.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• Cyproheptadine exhibits antitumor activity in urothelial carcinoma cells by targeting GSK3β to suppress mTOR and β-catenin signaling pathways

  Hsieh, H. Y., Shen, C. H., Lin, R. I., Feng, Y. M., Huang, S. Y., Wang, Y. H., Wu, S. F., Hsu, C. D. & Chan, M. W. Y., Jan 1 2016, In: Cancer Letters. 370, 1, p. 56-65 10 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Cysteinyl leukotriene receptor antagonist epigenetically modulates cytokine expression and maturation of human myeloid dendritic cells

  Kuo, C. H., Yang, S. N., Kuo, H. F., Lee, M. S., Huang, M. Y., Huang, S. K., Lin, Y. C., Hsieh, C. C. & Hung, C. H., Aug 1 2016, In: Pulmonary Pharmacology and Therapeutics. 39, p. 28-37 10 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Cytomegalovirus-infected duodenal ulcer with severe recurrent bleeding

  Chao, H. C. & Yu, W. L., Aug 1 2016, In: Journal of the Formosan Medical Association. 115, 8, p. 682-683 2 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Cytoplasmic localization of Nrf2 promotes colorectal cancer with more aggressive tumors via upregulation of PSMD4

  Lin, P. L., Chang, J. T., Wu, D. W., Huang, C. C. & Lee, H., Jun 1 2016, In: Free Radical Biology and Medicine. 95, p. 121-132 12 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Cytotoxic Lanostanoids from Poria cocos

  Lai, K. H., Lu, M. C., Du, Y. C., El-Shazly, M., Wu, T. Y., Hsu, Y. M., Henz, A., Yang, J. C., Backlund, A., Chang, F. R. & Wu, Y. C., Nov 23 2016, In: Journal of Natural Products. 79, 11, p. 2805-2813 9 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Damping Factor as a Diagnostic Parameter for Assessment of Osseointegration during the Dental Implant Healing Process: An Experimental Study in Rabbits

  Feng, S-W., Ho, K. N., Chan, Y. H., Chang, K. J., Lai, W. Y. & Huang, H-M., Dec 1 2016, In: Annals of Biomedical Engineering. 44, 12, p. 3668-3678 11 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Data analyses of honokiol-induced autophagy of human glioma cells in vitro and in vivo

  Wu, G. J., Lin, C. J., Lin, Y. W. & Chen, R. M., Dec 1 2016, In: Data in Brief. 9, p. 667-672 6 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Data Mining Applications in Clinical Implementation and Healthcare: Highlights of Findings, Interventions, and Future Directions

  Su, E. C-Y., Iqbal, U. & Li, Y-C., 2016, In: Computer Methods and Programs in Biomedicine.

  Research output: Contribution to journal › Editorial › peer-review

• Data on clinical significance of GAS2 in colorectal cancer cells

  Chang, C. C., Huang, C. C., Yang, S. H., Chien, C. C., Lee, C. L. & Huang, C. J., Sep 1 2016, In: Data in Brief. 8, p. 82-86 5 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Daytime sleepiness is independently associated with falls in older adults with dementia

  Chen, P. Y., Chiu, H. T. & Chiu, H. Y., Jul 1 2016, In: Geriatrics and Gerontology International. 16, 7, p. 850-855 6 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• DDA suppresses angiogenesis and tumor growth of colorectal cancer in vivo through decreasing VEGFR2 signaling

  Huang, S. W., Lien, J. C., Kuo, S. C. & Huang, T. F., Jan 1 2016, In: Oncotarget. 7, 39, p. 63124-63137 14 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• DDX3 enhances oncogenic KRAS-induced tumor invasion in colorectal cancer via the β-catenin/ZEB1 axis

  Wu, D. W., Lin, P. L., Cheng, Y. W., Huang, C. C., Wang, L. & Lee, H., Apr 19 2016, In: Oncotarget. 7, 16, p. 22687-22699 13 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

  He, T. Y., Wu, D. W., Lin, P. L., Wang, L., Huang, C. C., Chou, M. C. & Lee, H., Feb 19 2016, In: Scientific Reports. 6, 21483.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• Deacetylation of HSPA5 by HDAC6 leads to GP78-mediated HSPA5 ubiquitination at K447 and suppresses metastasis of breast cancer

  Chang, Y. W., Tseng, C. F., Wang, M. Y., Chang, W. C., Lee, C. C., Chen, L. T., Hung, M. C. & Su, J. L., Mar 24 2016, In: Oncogene. 35, 12, p. 1517-1528 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  48 Citations (Scopus)

• Dear Colleagues

  Tu, Y. K., Jan 1 2016, In: World Neurosurgery. 85, p. A13-A14

  Research output: Contribution to journal › Editorial › peer-review

• Deciphering the gene expression profile of peroxisome proliferator-activated receptor signaling pathway in the left atria of patients with mitral regurgitation

  Chen, M. C., Chang, J. P., Lin, Y. S., Pan, K. L., Ho, W. C., Liu, W. H., Chang, T. H., Huang, Y. K., Fang, C. Y. & Chen, C. J., Jun 2 2016, In: Journal of Translational Medicine. 14, 1, 157.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Decision-tree algorithm for optimized hematopoietic progenitor cell–based predictions in peripheral blood stem cell mobilization

  Wu, C. Y., Chiou, T. J., Liu, C. Y., Lin, F. C., Lin, J. S., Hung, M. H., Hsiao, L. T., Yen, C. C., Gau, J. P., Yen, H. J., Hung, G. Y., Hsu, H. C., Tzeng, C. H., Liu, J. H. & Yu, Y. B., Aug 1 2016, In: Transfusion. 56, 8, p. 2042-2051 10 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Decline in semen quality in men in Northern Taiwan between 2001 and 2010

  Li, C. J., Tzeng, C-R., Chen, R-Y., Han, B-C., Yeh, C-Y. & Chien, L-C., 2016, In: Chinese Journal of Physiology. 59, 6, p. 355-365 11 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Decoupled temporal variability and signal synchronization of spontaneous brain activity in loss of consciousness: An fMRI study in anesthesia

  Huang, Z., Zhang, J., Wu, J., Qin, P., Wu, X., Wang, Z., Dai, R., Li, Y., Liang, W., Mao, Y., Yang, Z., Wolff, A. & Northoff, G., 2016, In: NeuroImage. 124, p. 693-703 11 p.

  Research output: Contribution to journal › Article › peer-review
  62 Citations (Scopus)

• DEF6 expression in ovarian carcinoma correlates with poor patient survival

  Liew, P. L., Fang, C. Y., Lee, Y. C., Lee, Y. C., Chen, C. L. & Chu, J. S., Aug 3 2016, In: Diagnostic Pathology. 11, 1, 68.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Defect-Mediated Gold Substitution Doping in ZnO Mesocrystals and Catalysis in CO Oxidation

  Liu, M. H., Chen, Y. W., Liu, X., Kuo, J. L., Chu, M. W. & Mou, C. Y., Jan 4 2016, In: ACS Catalysis. 6, 1, p. 115-122 8 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• Deficiency of Soluble α-Klotho as an Independent Cause of Uremic Cardiomyopathy

  Xie, J., Wu, Y. L. & Huang, C. L., 2016, Klotho, 2016. Litwack, G. (ed.). Academic Press Inc., p. 311-330 20 p. (Vitamins and Hormones; vol. 101).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  10 Citations (Scopus)

• Depression and cholesteatoma: Preliminary findings from a nationwide population-based retrospective cohort study

  Kuo, C. L., Hsaoyen Chang, N., Shiao, A. S., Lien, C. F., Huang, H. L., Lin, S. H. & Chang, W. P., Apr 1 2016, In: Journal of Affective Disorders. 194, p. 222-225 4 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Depression as the primary cause of insomnia and excessive daytime sleepiness in a family with multiple cases of spinocerebellar ataxia

  Hsu, C. H., Chen, Y. L., Pei, D., Yu, S. M. & Liu, I. C., 2016, In: Journal of Clinical Sleep Medicine. 12, 7, p. 1059-1061 3 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Depressive symptome, kardiale regulation und kortikale verarbeitung bei leistungssportlern

  Translated title of the contribution: Depressive symptoms, cardiac control and cortical processing in athletesHerbert, C., Northoff, G. & Hautzinger, M., Jan 1 2016, In: Deutsche Zeitschrift fur Sportmedizin. 67, 12, p. 293-300 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Design, development, and clinical validation of therapeutic toys for autistic children

  Tseng, K. C., Tseng, S. H. & Cheng, H. Y. K., Jul 2016, In: Journal of Physical Therapy Science. 28, 7, p. 1972-1980 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents

  Chen, T. C., Yu, D-S., Chen, S-J., Chen, C-L., Lee, C-C., Hsieh, Y-Y., Chang, L-C., Guh, J-H., Lin, J-J. & Huang, H-S., 2016, In: Arabian Journal of Chemistry.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption

  Chen, C. L., Lee, C. C., Liu, F. L., Chen, T. C., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., Jul 19 2016, In: European Journal of Medicinal Chemistry. 117, p. 70-84 15 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Design and fabrication of identification inkjet print head chip fuse sensors

  Liou, J. C., Yang, C. F. & Gong, C. S., 2016, In: Sensors and Materials. 28, 5, p. 493-501 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Design and fabrication of multiplexer driver for InP-laser arrays with waveguide

  Liou, J. C., Gong, C. S. A., Yang, C. F. & Fang, Y. H., Feb 1 2016, In: Optical and Quantum Electronics. 48, 2, p. 1-14 14 p., 97.

  Research output: Contribution to journal › Article › peer-review

• Design and Fabrication of Printed DNA Droplets Arrangement and Detection Inkjet System

  Liou, J-C., Sep 28 2016, Printed Electronics - Current Trends and Applications. Yun, I. (ed.). Rijeka: InTech

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors

  Das, A., Adak, A. K., Ponnapalli, K., Lin, C. H., Hsu, K. C., Yang, J. M., Hsu, T. A. & Lin, C. C., Nov 10 2016, In: European Journal of Medicinal Chemistry. 123, p. 397-406 10 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents

  Chuang, H., Huang, L. C. S., Kapoor, M., Liao, Y. J., Yang, C. L., Chang, C. C., Wu, C. Y., Hwu, J. R., Huang, T. J. & Hsu, M. H., 2016, In: MedChemComm. 7, 5, p. 832-836 5 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Design of 20-Gb/s four-level pulse amplitude modulation VCSEL driver in 90-nm CMOS technology

  Li, J. Y., Jou, J. J., Shih, T. T., Chiu, C. L., Liou, J. C. & Ting, H. W., Dec 15 2016, 2016 IEEE International Conference on Electron Devices and Solid-State Circuits, EDSSC 2016. Institute of Electrical and Electronics Engineers Inc., p. 195-198 4 p. 7785242

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  5 Citations (Scopus)

• Design of a 0.5 v 1.68mW nose-on-a-chip for rapid screen of chronic obstructive pulmonary disease

  Chou, T. I., Chiu, S. W., Chang, K. H., Chen, Y. J., Tang, C. T., Shih, C. H., Hsieh, C. C., Chang, M. F., Yang, C. H., Chiueh, H. & Tang, K. T., 2016, Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016. Institute of Electrical and Electronics Engineers Inc., p. 592-595 4 p. 7833864

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  1 Citation (Scopus)