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• 2021

  Hidden diversity of the most basal tapeworms (Cestoda, Gyrocotylidea), the enigmatic parasites of holocephalans (Chimaeriformes)

  Barčák, D., Fan, C. K., Sonko, P., Kuchta, R., Scholz, T., Orosová, M., Chen, H. W. & Oros, M., Dec 2021, In: Scientific Reports. 11, 1, 5492.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• High-dose ferric citrate supplementation attenuates omega-3 polyunsaturated fatty acid biosynthesis via downregulating delta 5 and 6 desaturases in rats with high-fat diet-induced obesity

  Faradina, A., Tseng, S-H., Tung, T-H., Huang, S-Y., Lee, Y-C., Skalny, A. V., Tinkov, A. A., Chen, S-H., Chuang, Y-K. & Chang, J-S., Dec 7 2021, In: Food & function. 12, 23, p. 11819-11828 10 p.

  Research output: Contribution to journal › Article › peer-review

• Higher alveolar deposition of particulate matter in emphysematous lobes of COPD

  Tung, N. T., Ho, S. C., Lu, Y. H., Chen, T. T., Lee, K. Y., Chen, K. Y., Wu, C. D., Chung, K. F., Kuo, H. P., Thao, H. N. X., Dung, H. B., Thuy, T. P. C., Wu, S. M., Kou, H. Y., Lee, Y. L. & Chuang, H. C., 2021, In: ERJ Open Research. 7, 3, 00324-2021.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  2 Citations (Scopus)

• Higher body mass index associated with smaller frontal cortical volumes in older adult patients with bipolar disorder

  Chen, P. H., Hsu, J. L., Chung, K. H., Huang, S. H., Huang, Y. J. & Tsai, S. Y., 2021, (Accepted/In press) In: European Journal of Psychiatry. 35, 3, p. 157-165 9 p.

  Research output: Contribution to journal › Article › peer-review

• Higher-order sensorimotor circuit of the brain's global network supports human consciousness

  Qin, P., Wu, X., Wu, C., Wu, H., Zhang, J., Huang, Z., Weng, X., Zang, D., Qi, Z., Tang, W., Hiromi, T., Tan, J., Tanabe, S., Fogel, S., Hudetz, A. G., Yang, Y., Stamatakis, E. A., Mao, Y. & Northoff, G., May 1 2021, In: NeuroImage. 231, 117850.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Higher serum homocysteine level and frequency of hyperhomocysteinemia in carcinoembryonic antigen-positive or squamous cell carcinoma-antigen-positive oral leukoplakia patients

  Wu, Y. H., Lin, P. Y., Yang, J. H., Jin, Y. T. & Wu, Y. C., Dec 2021, In: Journal of the Formosan Medical Association. 120, 12, p. 2128-2135 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• High-flow nasal cannula for reducing hypoxemic events in patients undergoing bronchoscopy: A systematic review and metaanalysis of randomized trials

  Su, C. L., Chiang, L. L., Tam, K. W., Chen, T. T. & Hu, M. C., Dec 2021, In: PLoS ONE. 16, 12 December, e0260716.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  1 Citation (Scopus)

• High-grade b-cell lymphoma (Hgbl) with myc and bcl2 and/or bcl6 rearrangements is predominantly bcl6-rearranged and bcl6-expressing in Taiwan

  Tsai, C. C., Su, Y. C., Bamodu, O. A., Chen, B. J., Tsai, W. C., Cheng, W. H., Lee, C. H., Hsieh, S. M., Liu, M. L., Fang, C. L., Lin, H. T., Chen, C. L., Yeh, C. T., Lee, W. H., Ho, C. L., Lai, S. W., Tzeng, H. E., Hsieh, Y. Y., Chang, C. L., Zheng, Y. M. & 4 others, Liu, H. W., Yen, Y., Whang-Peng, J. & Chao, T. Y., Apr 1 2021, In: Cancers. 13, 7, 1620.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• High-intensity functional exercise in older adults with dementia: A systematic review and meta-analysis

  Yeh, S. W., Lin, L. F., Chen, H. C., Huang, L. K., Hu, C. J., Tam, K. W., Kuan, Y. C. & Hong, C. H., Feb 2021, In: Clinical Rehabilitation. 35, 2, p. 169-181 13 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• High-molecular-weight hyaluronic acid inhibits IL-1β-induced synovial inflammation and macrophage polarization through the GRP78-nf-κB signaling pathway

  Lee, C. H., Chiang, C. F., Kuo, F. C., Su, S. C., Huang, C. L., Liu, J. S., Lu, C. H., Hsieh, C. H., Wang, C. C., Lee, C. H. & Shen, P. H., Nov 1 2021, In: International journal of molecular sciences. 22, 21, 11917.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• High Risk and Trajectories of Physical Illnesses before the Diagnosis of Bipolar Disorder

  Chen, P. H., Tsai, S. Y., Pan, C. H., Chen, Y. L., Chang, H. M., Su, S. S., Chen, C. C. & Kuo, C. J., Feb 15 2021, In: Journal of Affective Disorders. 281, p. 99-108 10 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• High-SNR steganography for digital audio signal in the wavelet domain

  Chen, S. T., Huang, T. W. & Yang, C. T., Mar 2021, In: Multimedia Tools and Applications. 80, 6, p. 9597-9614 18 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• High tumor burden predicts poor response to enzalutamide in metastatic castration-resistant prostate cancer patients

  Hsieh, Y. T., Chiang, B. J., Wu, C. C., Liao, C. H., Lin, C. D. & Chen, C. H., Aug 2 2021, In: Cancers. 13, 16, 3966.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• High variability in model performance of Google relative search volumes in spatially clustered COVID-19 areas of the USA

  Husnayain, A., Chuang, T. W., Fuad, A. & Su, E. C. Y., Aug 2021, In: International Journal of Infectious Diseases. 109, p. 269-278 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hiltonol cocktail kills lung cancer cells by activating cancer-suppressors, pkr/oas and restraining the tumor microenvironment

  Chang, S. C., Zhang, B. X., Su, E. C. Y., Wu, W. C., Hsieh, T. H., Salazar, A. M., Lin, Y. K. & Ding, J. L., Feb 2 2021, In: International journal of molecular sciences. 22, 4, p. 1-23 23 p., 1626.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Hinokitiol exhibits antitumor properties through induction of ROS-mediated apoptosis and p53-driven cell-cycle arrest in endometrial cancer cell lines (Ishikawa, HEC-1A, KLE)

  Chen, H. Y., Cheng, W. P., Chiang, Y. F., Hong, Y. H., Ali, M., Huang, T. C., Wang, K. L., Shieh, T. M., Chang, H. Y. & Hsia, S. M., Aug 2021, In: International journal of molecular sciences. 22, 15, 8268.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Hip fracture in patients with non-dialysis chronic kidney disease stage 5

  Tang, C. H. & Chou, C. Y., Dec 2021, In: Scientific Reports. 11, 1, 20591.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Hippocampal and Orbitofrontal Theta Band Coherence Diminishes During Conflict Resolution

  Tang, A. M., Chen, K. H., Del Campo-Vera, R. M., Sebastian, R., Gogia, A. S., Nune, G., Liu, C. Y., Kellis, S. & Lee, B., Aug 2021, In: World Neurosurgery. 152, p. e32-e44

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Hippocampus-sparing whole-brain radiotherapy: Dosimetric comparison between non-coplanar and coplanar planning

  Chen, L. J., Li, M. H., Cheng, H. W., Kuo, C. Y., Sun, W. L. & Tsai, J. T., Mar 2021, In: Therapeutic Radiology and Oncology. 5, March, 1.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Histology changes of in vivo human skin after treatment with fractional 1064 nm Nd:YAG picosecond laser in different energy settings

  Chang, Y. S., Yang, T. H. & Li, C. N., 2021, (Accepted/In press) In: Lasers in Medical Science.

  Research output: Contribution to journal › Article › peer-review

• Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

  Yang, W. B., Wu, A. C., Hsu, T. I., Liou, J. P., Lo, W. L., Chang, K. Y., Chen, P. Y., Kikkawa, U., Yang, S. T., Kao, T. J., Chen, R. M., Chang, W. C., Ko, C. Y. & Chuang, J. Y., Oct 2021, In: Cell Death and Disease. 12, 10, 884.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Histone deacetylase 7 mediates endothelin-1-induced connective tissue growth factor expression in human lung fibroblasts through p300 and activator protein-1 activation

  Hua, H. S., Wen, H. C., Weng, C. M., Lee, H. S., Chen, B. C. & Lin, C. H., Dec 2021, In: Journal of Biomedical Science. 28, 1, 38.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Histone methyltransferase g9a-promoted progression of hepatocellular carcinoma is targeted by liver-specific hsa-mir-122

  Yuan, L. T., Lee, W. J., Yang, Y. C., Chen, B. R., Yang, C. Y., Chen, M. W., Chen, J. Q., Hsiao, M., Chien, M. H. & Hua, K. T., May 2 2021, In: Cancers. 13, 10, 2376.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Honokiol/magnolol-loaded self-assembling lecithin-based mixed polymeric micelles (lbMPMs) for improving solubility to enhance oral bioavailability

  Lin, H. L., Cheng, W. T., Chen, L. C., Ho, H. O., Lin, S. Y. & Hsieh, C. M., 2021, In: International Journal of Nanomedicine. 16, p. 651-665 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Honokiol inhibits arecoline-induced oral fibrogenesis through transforming growth factor-β/Smad2/3 signaling inhibition

  Chen, P. Y., Ho, D. C. Y., Liao, Y. W., Hsieh, P. L., Lu, K. H., Tsai, L. L., Su, S. H. & Yu, C. C., 2021, (Accepted/In press) In: Journal of the Formosan Medical Association.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Hospital Board of Directors’ Composition and Financial Performance: Empirical Evidence from Taiwan

  Chen, K. C., Hsieh, F. C. & Hsiao, Y. J., 2021, In: Inquiry (United States). 58

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Household transmission but without the community-acquired outbreak of COVID-19 in Taiwan

  Hsu, C. Y., Wang, J. T., Huang, K. C., Fan, A. C. H., Yeh, Y. P. & Chen, S. L. S., Jun 2021, In: Journal of the Formosan Medical Association. 120, p. S38-S45

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Citations (Scopus)

• How does culture influence the implementation of strategy training in stroke rehabilitation? A rapid ethnographic study of therapist perspectives in Taiwan and the United States

  Chang, F. H., Fields, B. E., Kersey, J. M., Wu, C. Y., Shih, M. & Skidmore, E. R., 2021, (Accepted/In press) In: Disability and Rehabilitation.

  Research output: Contribution to journal › Article › peer-review

• How to perform immediate implant placement and provisionalization in patients with posterior bite collapse and premature contact of an anterior tooth - A case report

  Tseng, C-W., Chuang, H-C., Chen, P-H. & Fang, C-Y., Oct 2021, In: Journal of Dental Sciences. 16, 4, p. 1317-1319 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  2 Citations (Scopus)

• Hsa-miR-107 regulates chemosensitivity and inhibits tumor growth in hepatocellular carcinoma cells

  Chen, H. A., Li, C. C., Lin, Y. J., Wang, T. F., Chen, M. C., Su, Y. H., Yeh, Y. L., Padma, V. V., Liao, P. H. & Huang, C. Y., 2021, In: Aging. 13, 8, p. 12046-12057 12 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Huge brain abscess caused by Actinomyces israelii associated with chronic sinusitis: A rare case report

  Chou, L. H., Su, Y. S., Chen, F. L., Lee, W. S. & Li, W. H., 2021, (Accepted/In press) In: Journal of Microbiology, Immunology and Infection.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Human antigen R regulates hypoxia-induced mitophagy in renal tubular cells through PARKIN/BNIP3L expressions

  Yu, S. H., Palanisamy, K., Sun, K. T., Li, X., Wang, Y. M., Lin, F. Y., Chen, K. B., Wang, I. K., Yu, T. M. & Li, C. Y., Mar 2021, In: Journal of Cellular and Molecular Medicine. 25, 5, p. 2691-2702 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Human biomonitoring reference values and characteristics of Phthalate exposure in the general population of Taiwan: Taiwan Environmental Survey for Toxicants 2013–2016

  Liao, K. W., Chang, W. H., Chou, W. C., Huang, H. B., Waits, A., Chen, P. C. & Huang, P. C., Jun 2021, In: International Journal of Hygiene and Environmental Health. 235, 113769.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Human ipsc-derived neurons as a platform for deciphering the mechanisms behind brain aging

  Chao, C. C., Shen, P. W., Tzeng, T. Y., Kung, H. J., Tsai, T. F. & Wong, Y. H., Nov 2021, In: Biomedicines. 9, 11, 1635.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment

  Nebie, O., Carvalho, K., Barro, L., Delila, L., Faivre, E., Renn, T-Y., Chou, M-L., Wu, Y-W., Niem-Redene, A., Chou, S-Y., Buée, L., Hu, C-J., Peng, C-W., Devos, D., Blum, D. & Burnouf, T., Oct 1 2021, In: Brain. 144, 10, p. 3142-3158 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Human platelet lysates for human cell propagation

  Barro, L., Burnouf, P. A., Chou, M. L., Nebie, O., Wu, Y. W., Chen, M. S., Radosevic, M., Knutson, F. & Burnouf, T., 2021, In: Platelets. 32, 2, p. 152-162 11 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation

  Yu, D. C. W., Wu, F. C., Wu, C. E., Chow, L. P., Ho, H. N. & Chen, H. F., Jan 2021, In: iScience. 24, 1, 102003.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyaluronic acid supplement as a chondrogenic adjuvant in promoting the therapeutic efficacy of stem cell therapy in cartilage healing

  Wong, C. C., Sheu, S. D., Chung, P. C., Yeh, Y. Y., Chen, C. H., Chang, Y. W. & Kuo, T. F., Mar 2021, In: Pharmaceutics. 13, 3, 432.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Hybrid Surgeons Play a Mainstay Role in the Endovascular Era

  Lee, T. S., Chen, F. C. & Li, S. J., Mar 2021, In: Annals of Thoracic Surgery. 111, 3, p. 1091-1092 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Citation (Scopus)

• Hybrid ZnO/chitosan antimicrobial coatings with enhanced mechanical and bioactive properties for titanium implants

  Lin, M. H., Wang, Y. H., Kuo, C. H., Ou, S. F., Huang, P. Z., Song, T. Y., Chen, Y. C., Chen, S. T., Wu, C. H., Hsueh, Y. H. & Fan, F. Y., Apr 1 2021, In: Carbohydrate Polymers. 257, 117639.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Hydrogen Bond Strength-Mediated Self-Assembly of Supramolecular Nanogels for Selective and Effective Cancer Treatment

  Ilhami, F. B., Yang, Y. T., Lee, A. W., Chiao, Y. H., Chen, J. K., Lee, D. J., Lai, J. Y. & Cheng, C. C., Oct 11 2021, In: Biomacromolecules. 22, 10, p. 4446-4457 12 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Hydrogen sulfide attenuates aortic remodeling in aortic dissection associating with moderated inflammation and oxidative stress through a NO-dependent pathway

  Lu, H. Y., Hsu, H. L., Li, C. H., Li, S. J., Lin, S. J., Shih, C. M. & Shih, C. C., May 2021, In: Antioxidants. 10, 5, 682.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Hydrolysable tannins exhibit acetylcholinesterase inhibitory and anti-glycation activities in vitro and learning and memory function improvements in scopolamine-induced amnesiac mice

  Chen, L. G., Lin, S. Y., Lee, Y. S., Wang, C. C. & Hou, W. C., Aug 2021, In: Biomedicines. 9, 8, 1066.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hydrothermal Synthesis of Co₃O₄/ZnCo₂O₄Core-Shell Nanostructures for High-Performance Supercapacitors

  Lin, E. S., Chao, F. S., Liang, C. J., Chang, C. J., Fang, A., Lin, C. K., Chang, Y. C., Tsay, C. Y., Wu, J. J. & Chen, C. Y., Dec 2021, In: Journal of the Electrochemical Society. 168, 12, 123502.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Hydroxychloroquine (Hcq) modulates autophagy and oxidative dna damage stress in hepatocellular carcinoma to overcome sorafenib resistance via tlr9/sod1/hsa-mir-30a5p/beclin-1 axis

  Chen, M. Y., Yadav, V. K., Chu, Y. C., Ong, J. R., Huang, T. Y., Lee, K. F., Lee, K. H., Yeh, C. T. & Lee, W. H., Jul 1 2021, In: Cancers. 13, 13, 3227.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Hyperbaric oxygen therapy alleviates the autoimmune encephalomyelitis via the reduction of IL-17a and GM-CSF production of autoreactive T cells as well as boosting the immunosuppressive IL-10 in the central nervous system tissue lesions

  Chiou, H. Y. C., Huang, S. H., Hung, C. H., Tsai, S. M., Kuo, H. R., Huang, Y. R., Wang, J. W., Chen, S. C., Kuo, C. H., Wu, D. C., Huang, S. K., Hsu, S. H. & Lin, M. H., Aug 2021, In: Biomedicines. 9, 8, 943.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyperlipidemia Is a Risk Factor of Adhesive Capsulitis: Real-World Evidence Using the Taiwanese National Health Insurance Research Database

  Wang, J. Y., Liaw, C. K., Huang, C. C., Liou, T. H., Lin, H. W. & Huang, S. W., 2021, In: Orthopaedic Journal of Sports Medicine. 9, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver

  Lin, H., Huang, Y. S., Fustin, J. M., Doi, M., Chen, H., Lai, H. H., Lin, S. H., Lee, Y. L., King, P. C., Hou, H. S., Chen, H. W., Young, P. Y. & Chao, H. W., Dec 2021, In: Nature Communications. 12, 1, p. 645 645.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Citations (Scopus)

• Hypoxia Induced by Cobalt Chloride Triggers Autophagic Apoptosis of Human and Mouse Drug-Resistant Glioblastoma Cells through Targeting the PI3K-AKT-mTOR Signaling Pathway

  Lee, Y. W., Cherng, Y. G., Yang, S. T., Liu, S. H., Chen, T. L. & Chen, R. M., 2021, In: Oxidative Medicine and Cellular Longevity. 2021, 5558618.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

  Cheng, W. H., Chen, C. L., Chen, J. Y., Lin, C. H. & Chen, B-C., Dec 2021, In: Molecular Medicine. 27, 1, 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access