Find Research Outputs

2018
1 Citation (Scopus)

4-acetyl-antroquinonol B suppresses SOD2-enhanced cancer stem cell-like phenotypes and chemoresistance of colorectal cancer cells by inducing hsa-miR-324 re-expression

Bamodu, O. A., Yang, C. K., Cheng, W. H., Tzeng, D. T. W., Kuo, K. T., Huang, C. C., Deng, L., Hsiao, M., Lee, W. H. & Yeh, C. T., Aug 10 2018, In : Cancers. 10, 8, 269.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Colorectal Neoplasms
oxaliplatin
Phenotype
Fluorouracil

4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy

Lin, S. Y., Yeh, T. K., Song, J. S., Hung, M. S., Cheng, M. F., Liao, F. Y., Li, A. S., Cheng, S. Y., Lin, L. M., Chiu, C. H., Wu, M. H., Lin, Y. J., Hsiao, W., Sun, M., Wang, Y. H., Huang, C. H., Tang, Y. C., Chang, H. H., Huang, Z. T., Chao, Y. S. & 5 othersShih, C., Pan, S. L., Wu, S. Y., Kuo, C. C. & Ueng, S. H., Apr 1 2018, In : Bioorganic Chemistry. 77, p. 600-607 8 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tumors
Neoplasms
T-cells
Pharmaceutical Preparations
1 Citation (Scopus)

4-O-Caffeoylquinic acid as an antioxidant marker for mulberry leaves rich in phenolic compounds

Ganzon, J. G., Chen, L. G. & Wang, C. C., 2018, In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

Morus
mulberries
phenolic compounds
Antioxidants
antioxidants
2 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
2 Citations (Scopus)

A 5' AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma

Weng, J. R., Dokla, E. M. E., Bai, L. Y., Chen, C. S., Chiu, S. J. & Shieh, T. M., Jan 1 2018, (Accepted/In press) In : Basic and Clinical Pharmacology and Toxicology.

Research output: Contribution to journalArticle

Enzyme Activators
AMP-Activated Protein Kinases
Autophagy
Squamous Cell Carcinoma
Protein Tyrosine Phosphatases

AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage

Fang, C. C., Wu, C. F., Liao, Y. J., Huang, S. F., Chen, M. & Chen, Y. M. A., Dec 1 2018, In : Scientific Reports. 8, 1, 13802.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Dependovirus
Carbon Tetrachloride
Hepatocellular Carcinoma
Liver
5 Citations (Scopus)

A bacterial pioneer produces cellulase complexes that persist through community succession

Kolinko, S., Wu, Y. W., Tachea, F., Denzel, E., Hiras, J., Gabriel, R., Bäcker, N., Chan, L. J. G., Eichorst, S. A., Frey, D., Chen, Q., Azadi, P., Adams, P. D., Pray, T. R., Tanjore, D., Petzold, C. J., Gladden, J. M., Simmons, B. A. & Singer, S. W., Jan 1 2018, In : Nature Microbiology. 3, 1, p. 99-107 9 p.

Research output: Contribution to journalArticle

Cellulase
Glycoside Hydrolases
Cellulosomes
Microbial Consortia
Metagenomics
10 Citations (Scopus)

Abnormal Resting-State Connectivity in a Substantia Nigra-Related Striato-Thalamo-Cortical Network in a Large Sample of First-Episode Drug-Naïve Patients With Schizophrenia

Martino, M., Magioncalda, P., Yu, H., Li, X., Wang, Q., Meng, Y., Deng, W., Li, Y., Li, M., Ma, X., Lane, T., Duncan, N. W., Northoff, G. & Li, T., Feb 15 2018, In : Schizophrenia Bulletin. 44, 2, p. 419-431 13 p.

Research output: Contribution to journalArticle

Substantia Nigra
Schizophrenia
Dopamine
Pharmaceutical Preparations
Thalamus

A Case of Behçet’s Disease with Pulmonary Artery Aneurysm and Deep Venous Thrombosis

Chiang, Y., Lai, H-Y. & Lan, G-Y., 2018, RSROC2018中華民國放射線醫學會.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Venous Thrombosis
Pulmonary Artery
Aneurysm
Thrombosis
Thorax
Return to Work
Head and Neck Neoplasms
Survivors
Appointments and Schedules
Taiwan
4 Citations (Scopus)
Clinical Decision Support Systems
Medical Order Entry Systems
Physicians
Health Facilities
Drug-Related Side Effects and Adverse Reactions
1 Citation (Scopus)

A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer

Huang, E. Y., Chang, Y. J., Huang, S. P., Lin, V. C., Yu, C. C., Huang, C. Y., Yin, H. L., Chang, T. Y., Lu, T. L. & Bao, B. Y., Jul 1 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3661-3670 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Single Nucleotide Polymorphism
Recurrence
Survival
Glycosyltransferases
6 Citations (Scopus)

A comparison study of SiO2/nano metal oxide composite sphere for antibacterial application

Hou, Y. X., Abdullah, H., Kuo, D. H., Leu, S. J., Gultom, N. S. & Su, C. H., Jan 15 2018, In : Composites Part B: Engineering. 133, p. 166-176 11 p.

Research output: Contribution to journalArticle

Oxides
Metals
Composite materials
Nanoparticles
Light emitting diodes

A composite of exhaled LTB4, LXA4, FeNO, and FEV1 as an “asthma classification ratio” characterizes childhood asthma

Chen, L. C., Tseng, H. M., Kuo, M. L., Chiu, C. Y., Liao, S. L., Su, K. W., Tsai, M. H., Hua, M. C., Lai, S. H., Yao, T. C., Yeh, K. W., Wu, A. H., Huang, J. L. & Huang, S. K., Mar 1 2018, In : Allergy: European Journal of Allergy and Clinical Immunology. 73, 3, p. 627-634 8 p.

Research output: Contribution to journalArticle

Leukotriene B4
Asthma
Eicosanoids
Leukotriene E4
Dinoprostone

A cross-disciplinary successful aging intervention and evaluation: Comparison of person-to-person and digital-assisted approaches

Hsu, H. C., Kuo, T., Lin, J. P., Hsu, W. C., Yu, C. W., Chen, Y. C., Xie, W. Z., Hsu, W. C., Hsu, Y. L. & Yu, M. T., May 4 2018, In : International Journal of Environmental Research and Public Health. 15, 5, 0913.

Research output: Contribution to journalArticle

Health
Aptitude
Family Relations
Psychological Adaptation
Disease Management
2 Citations (Scopus)

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cardiac Myocytes
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Enzymes
3 Citations (Scopus)

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Fibroblasts
Nicotine
Chemical activation
Cells
Oxidative stress
MAP Kinase Signaling System
Nicotinic Receptors
Spasm
p38 Mitogen-Activated Protein Kinases

Active Tumor-Targeted co-Delivery of Epigallocatechin Gallate and Doxorubicin in Nanoparticles for Combination Gastric Cancer Therapy

Mi, F. L., Wang, L. F., Chu, P. Y., Peng, S. L., Feng, C. L., Lai, Y. J., Li, J. N. & Lin, Y. H., Aug 13 2018, In : ACS Biomaterials Science and Engineering. 4, 8, p. 2847-2859 13 p.

Research output: Contribution to journalArticle

Doxorubicin
Tumors
Cells
Nanoparticles
Hyaluronic acid

Acute aortoiliac thrombosis due to minimal change disease

Tam, W. C., Lin, C. H., Chuang, C. Y. & Cheng, C. Y., Apr 1 2018, In : Nephrology. 23, 4, p. 377-378 2 p.

Research output: Contribution to journalLetter

Lipoid Nephrosis
Thrombosis
1 Citation (Scopus)

Acute biliary events during anti-tuberculosis treatment: Hospital case series and a nationwide cohort study

Chang, L. Y., Lee, C. H., Chang, C. H., Lee, M. C., Lee, M. R., Wang, J. Y. & Lee, L. N., Feb 1 2018, In : BMC Infectious Diseases. 18, 1, 64.

Research output: Contribution to journalArticle

Chronic Disease Hospitals
Tuberculosis
Cohort Studies
Pulmonary Tuberculosis
Therapeutics
2 Citations (Scopus)

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

Chen, Y. P., Kuo, W. W., Baskaran, R., Day, C. H., Chen, R. J., Wen, S. Y., Ho, T. J., Padma, V. V., Kuo, C. H. & Huang, C. Y., Apr 1 2018, In : Journal of Cellular Biochemistry. 119, 4, p. 3363-3372 10 p.

Research output: Contribution to journalArticle

Glucose Transporter Type 4
Palmitic Acid
Cardiac Myocytes
Fatty Acids
Apoptosis

ADAM17/EGFR-dependent ERK activation mediates thrombin-induced CTGF expression in human lung fibroblasts

Chen, H. Y., Lin, C. H. & Chen, B. C., Sep 1 2018, In : Experimental Cell Research. 370, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

Connective Tissue Growth Factor
Disintegrins
Extracellular Signal-Regulated MAP Kinases
Metalloproteases
Epidermal Growth Factor Receptor
Subacute Care
Outpatients
Rehabilitation
Taiwan
Reproducibility of Results
1 Citation (Scopus)

Addressing stem cell therapeutic approaches in pathobiology of diabetes and its complications

Peng, B. Y., Dubey, N. K., Mishra, V. K., Tsai, F. C., Dubey, R., Deng, W. P. & Wei, H. J., Jan 1 2018, In : Journal of Diabetes Research. 2018, 7806435.

Research output: Contribution to journalArticle

Diabetes Complications
Diabetes Mellitus
Stem Cells
Multipotent Stem Cells
Pluripotent Stem Cells

A Descriptive, Retrospective Study of Using an Oblique Downward-design Gluteus Maximus Myocutaneous Flap for Reconstruction of Ischial Pressure Ulcers

Chou, C. Y., Sun, Y. S., Shih, Y. J., Tzeng, Y. S., Chang, S. C., Dai, N. T. & Lin, C. T., Mar 1 2018, In : Ostomy/wound management. 64, 3, p. 40-44 5 p.

Research output: Contribution to journalArticle

Myocutaneous Flap
Pressure Ulcer
Retrospective Studies
Wound Healing
Ulcer
1 Citation (Scopus)

A developed NK-92MI cell line with siglec-7neg phenotype exhibits high and sustainable cytotoxicity against leukemia cells

Huang, C. H., Liao, Y. J., Fan, T. H., Chiou, T. J., Lin, Y. H. & Twu, Y. C., Apr 4 2018, In : International Journal of Molecular Sciences. 19, 4, 1073.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
phenotype
leukemias
Cytotoxicity
cultured cells
Dipeptidyl-Peptidase IV Inhibitors
Keratinocytes
Wound Healing
Adiponectin
Medical problems
1 Citation (Scopus)

Adiponectin gene polymorphisms and obesity increase the susceptibility to arsenic-related renal cell carcinoma

Hsueh, Y. M., Chen, W. J., Lin, Y. C., Huang, C. Y., Shiue, H. S., Yang, S. M., Ao, P. L., Pu, Y. S. & Su, C. T., Jul 1 2018, In : Toxicology and Applied Pharmacology. 350, p. 11-20 10 p.

Research output: Contribution to journalArticle

Adiponectin
Arsenic
Polymorphism
Renal Cell Carcinoma
Obesity
4 Citations (Scopus)
Adjuvant Radiotherapy
Adjuvant Chemoradiotherapy
Adjuvant Chemotherapy
Adenocarcinoma
Chemoradiotherapy
1 Citation (Scopus)

Adolescent tobacco coupon receipt, vulnerability characteristics and subsequent tobacco use: Analysis of PATH Study, Waves 1 and 2

Rose, S. W., Glasser, A. M., Zhou, Y., Cruz, T. B., Cohn, A. M., Lienemann, B. A., Byron, M. J., Huang, L. L., Meissner, H. I., Baezconde-Garbanati, L. & Unger, J. B., Feb 22 2018, (Accepted/In press) In : Tobacco Control.

Research output: Contribution to journalArticle

Tobacco Use
nicotine
Tobacco
vulnerability
adolescent

Adverse Drug Reaction Post Classification with Imbalanced Classification Techniques

Wang, C. K., Dai, H. J., Wang, F. D. & Su, E. C. Y., Dec 24 2018, Proceedings - 2018 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2018. Institute of Electrical and Electronics Engineers Inc., p. 5-9 5 p. 8588467. (Proceedings - 2018 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pharmacodynamics
Artificial intelligence
Classifiers
Marketing
Health
8 Citations (Scopus)

Adverse outcomes of long-term use of proton pump inhibitors: a systematic review and meta-analysis

Islam, M. M., Poly, T. N., Walther, B. A., Dubey, N. K., Anggraini Ningrum, D. N., Shabbir, S-A. & Jack Li, Y-C., Dec 1 2018, In : European Journal of Gastroenterology and Hepatology. 30, 12, p. 1395-1405 11 p.

Research output: Contribution to journalReview article

Proton Pump Inhibitors
Meta-Analysis
Odds Ratio
Confidence Intervals
Hip Fractures

A facile measurement for monitoring dragline silk dope concentration in Nephila pilipes upon spinning

Wu, H. C., Wu, S. R., Yang, T. C. K. & Yang, J. C., Oct 12 2018, In : Materials. 11, 10, 1951.

Research output: Contribution to journalArticle

Silk
Monitoring
Liquids
Fibers
Tensile strength

A Functional Near-Infrared Spectroscopy Study of State Anxiety and Auditory Working Memory Load

Tseng, Y. L., Lu, C. F., Wu, S. M., Shimada, S., Huang, T. & Lu, G. Y., Aug 7 2018, In : Frontiers in Human Neuroscience. 12, 313.

Research output: Contribution to journalArticle

Near-Infrared Spectroscopy
Prefrontal Cortex
Short-Term Memory
Anxiety
Acoustic Stimulation

Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage

Jian, Q. L., HuangFu, W. C., Lee, Y. H. & Liu, I. H., Jan 1 2018, In : PeerJ. 2018, 10, e5739.

Research output: Contribution to journalArticle

chondrocytes
Cartilage
Zebrafish
Chondrocytes
Danio rerio
1 Citation (Scopus)
Lung Neoplasms
Survival
Actigraphy
Mortality
Proportional Hazards Models
1 Citation (Scopus)

A gelatin hydrogel-containing nano-organic PEI–Ppy with a photothermal responsive effect for tissue engineering applications

Satapathy, M. K., Nyambat, B., Chiang, C. W., Chen, C. H., Wong, P. C., Ho, P. H., Jheng, P. R., Burnouf, T., Tseng, C. L. & Chuang, E. Y., Jan 1 2018, In : Molecules. 23, 6, 1256.

Research output: Contribution to journalArticle

tissue engineering
Hydrogel
gelatins
Gelatin
Tissue Engineering
4 Citations (Scopus)

Aging modulates the substrate and triggers remodeling in atrial fibrillation

Lin, Y. K., Chen, Y. A., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : Circulation Journal. 82, 5, p. 1237-1244 8 p.

Research output: Contribution to journalReview article

Atrial Fibrillation
Atrial Remodeling
Muscular Diseases
Comorbidity
Veins

A hackathon promoting Taiwanese health-IoT innovation

Iqbal, U., Dagan, A., Syed-Abdul, S., Celi, L. A., Hsu, M-H. & Li, Y-CJ., 2018, In : Computer Methods and Programs in Biomedicine. 163, p. 29-32 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A high sensitivity bead-based immunoassay with nanofluidic preconcentration for biomarker detection

Fan, Y. J., Deng, C. Z., Chung, P. S., Tian, W. C. & Sheen, H. J., Nov 1 2018, In : Sensors and Actuators, B: Chemical. 272, p. 502-509 8 p.

Research output: Contribution to journalArticle

Nanofluidics
immunoassay
biomarkers
Biomarkers
antigens

A High-Speed High-Voltage Bipolar Pulser for Medical Ultrasonic Imaging Applications

Huang, Y. C., Chen, K. T., Lu, K. Y., Liou, J. C. & Wu, G. Z., Aug 27 2018, 2018 IEEE International Conference on Consumer Electronics-Taiwan, ICCE-TW 2018. Institute of Electrical and Electronics Engineers Inc., 8448428. (2018 IEEE International Conference on Consumer Electronics-Taiwan, ICCE-TW 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ultrasonic imaging
Medical imaging
high voltages
ultrasonics
high speed

A hybrid session key exchange algorithm for highly-sensitive IP-based institutional communications

Zhuang, Z. Y., Hsu, Y. C., Nurmi, K., Chen, Y. C., Liu, H. H. & Tseng, T. S., Jan 1 2018, In : Microsystem Technologies. 24, 1, p. 273-283 11 p.

Research output: Contribution to journalArticle

communication
Communication
Electronic document identification systems
exchanging
Security of data

AIDS incidence trends at presentation and during follow-up among HIV-at-risk populations: A 15-year nationwide cohort study in Taiwan

Lee, C. Y., Jen, I. A., Lan, Y. C., Yen, Y. F., Chuang, P. H., Chen, M., Lee, Y. & Chen, Y. M. A., May 3 2018, In : BMC Public Health. 18, 1, 589.

Research output: Contribution to journalArticle

Taiwan
Acquired Immunodeficiency Syndrome
Cohort Studies
HIV
Incidence

AI in Medicine: Big Data Remains a Challenge

Lin, M. C., Iqbal, U. & Li, Y. C., Oct 1 2018, In : Computer Methods and Programs in Biomedicine. 164, p. A1

Research output: Contribution to journalEditorial

Medicine
Big data
1 Citation (Scopus)

A Large Urinary Bladder Hemangioma Mimicking Urachal Cancer: A Case Report and Literature Review

Syu, S. H., Chan, K. S., Hsiao, C. H., Chen, W. Y., Lee, L. M. & Wen, Y. C., Jan 1 2018, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Hemangioma
Urinary Bladder
Hematuria
Urachus
Cavernous Hemangioma
Laminaria
Seaweed
Sodium-Hydrogen Antiporter
Chronic Renal Insufficiency
Protein Isoforms
5 Citations (Scopus)

A low microRNA-630 expression confers resistance to tyrosine kinase inhibitors in EGFR-mutated lung adenocarcinomas via miR-630/YAP1/ERK feedback loop

Wu, D. W., Wang, Y. C., Wang, L., Chen, C. Y. & Lee, H., Jan 1 2018, In : Theranostics. 8, 5, p. 1256-1269 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Protein-Tyrosine Kinases
bcl-Associated Death Protein
Neoplasms
Adenocarcinoma of lung

Alpha-lipoic acid suppresses N ε -(carboxymethyl) lysine-induced epithelial mesenchymal transition in HK-2 human renal proximal tubule cells

Lo, M. C., Chen, M. H., Hsueh, Y. T., Kuo, Y. T. & Lee, H. M., Dec 2 2018, In : Free Radical Research. 52, 11-12, p. 1387-1397 11 p.

Research output: Contribution to journalArticle

Thioctic Acid
Proximal Kidney Tubule
Epithelial-Mesenchymal Transition
Hypoxia-Inducible Factor 1
Reactive Oxygen Species

Alpinate Oxyphyllae extracts enhance the longevity and homing of mesenchymal stem cells and augment their protection against senescence in H9c2 cells

Chang, Y. M., Asokan Shibu, M., Tsai, C. T., Tsai, C. C., Lin, S. L., Chang, C. C., Viswanadha, V. P., Chen, R. J., Chang, J. H. M. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Stem Cells
Doxorubicin
CXC Chemokines