Find Research Outputs

2019

Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

Misko, T. A., Liu, Y. T., Harris, M. E., Oleinick, N. L., Pink, J., Lee, H. Y. & Dealwis, C. G., Jan 1 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 438-450 13 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Hydrazones
Neoplasms
Pancreatic Neoplasms
Catalytic Domain
Fibromyalgia
Sleep
Pain
Social Adjustment
Cognition
1 Citation (Scopus)

Subjective wellbeing, suicide and socioeconomic factors: an ecological analysis in Hong Kong

Hsu, C-Y., Chang, S-S. & Yip, P. S. F., Feb 2019, In : Epidemiology and Psychiatric Sciences. 28, 1, p. 112-130 19 p.

Research output: Contribution to journalArticle

Hong Kong
Suicide
Statistical Factor Analysis
Happiness
Population
Unsaturated Dietary Fats
Fish Oils
retinoic acid
Tretinoin
fish oils

Surface characterization and thermomechanical behavior of nanostructured-gold layer for biomedical applications

Wu, C. M., Lu, Y. J., Chen, S. Y., Wen, S. C., Wu, C. H., Liao, P. B., Ou, K. L. & Chou, H. H., Apr 25 2019, In : Journal of Alloys and Compounds. 782, p. 1114-1120 7 p.

Research output: Contribution to journalArticle

Gold
Electrodes
Stainless Steel
Electrosurgery
Stainless steel

Surface modification of Ni(OH) 2 nanosheets with PEDOT:PSS for supercapacitor and bendable electrochromic applications

Lee, K. C., Chang-Jian, C. W., Cho, E. C., Huang, J. H., Lin, W. T., Ho, B. C., Chou, J. A. & Hsiao, Y. S., Jun 15 2019, In : Solar Energy Materials and Solar Cells. 195, p. 1-11 11 p.

Research output: Contribution to journalArticle

Nanosheets
Electrochromic devices
Surface treatment
Chemical resistance
Mechanical stability

Synchronized expressions of serum OPN and BAFF in autoimmune thyroid disease

Cheng, C-W., Tang, K-T., Fang, W-F. & Lin, J-D., Apr 29 2019, In : European Journal of Clinical Investigation. p. e13122

Research output: Contribution to journalArticle

Osteopontin
Thyroid Diseases
Autoimmune Diseases
Hashimoto Disease
Serum
Lipolysis
Cyclic AMP-Dependent Protein Kinases
Adipocytes
Protein Kinases
Lipase
Urinary Bladder Neoplasms
Antineoplastic Agents
G1 Phase
Ovarian Neoplasms
Solubility
Crohn Disease
Meta-Analysis
Tumor Necrosis Factor-alpha
Incidence
Physiologic Monitoring
1 Citation (Scopus)

TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

Lai, H-H., Li, C-W., Hong, C-C., Sun, H-Y., Chiu, C-F., Ou, D-L. & Chen, P-S., Jan 18 2019, In : Molecular Oncology.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Response Elements
Transcriptional Activation
Hepatocellular Carcinoma
Neoplastic Stem Cells

The alteration of gut microbiota in newly-diagnosed type 2 diabetic patients

Chen, P-C., Chien, Y-W. & Yang, S-C., Jul 2019, In : Nutrition. 63, p. 51-56

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Clostridium
Lactobacillus
Dysbiosis
Therapeutics

The antipsychotic chlorpromazine suppresses YAP signaling, stemness properties, and drug resistance in breast cancer cells

Yang, C. E., Lee, W. Y., Cheng, H. W., Chung, C. H., Mi, F. L. & Lin, C. W., Apr 1 2019, In : Chemico-Biological Interactions. 302, p. 28-35 8 p.

Research output: Contribution to journalArticle

Chlorpromazine
Drug Resistance
Antipsychotic Agents
Stem cells
Cells
1 Citation (Scopus)
Periodontal Pocket
Tooth Root
Endodontics
Abscess
Logistic Models

The association between fecal hemoglobin concentration and oral potentially malignant disorders

Yen, A. M. F., Wang, S. T., Feng, S. W., Lin, C. T. & Chen, S. L. S., Jan 1 2019, In : Oral Diseases. 25, 1, p. 108-116 9 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Hemoglobins
Early Detection of Cancer
Longitudinal Studies
Colorectal Neoplasms
Selenium
Arsenic
Cadmium
selenium
Chronic Renal Insufficiency
titanium alloys
Blasting
blasts
Titanium alloys
Cell culture
Photogrammetry
Cleft Lip
Skin
Lip
Cicatrix
Voice Disorders
Dysphonia
Taiwan
Epidemiology
International Classification of Diseases

The expanding morphological and genetic spectrum of MYOD1-mutant spindle cell/sclerosing rhabdomyosarcomas: a clinicopathological and molecular comparison of mutated and non-mutated cases

Tsai, J. W., ChangChien, Y. C., Lee, J. C., Kao, Y-C., Li, W. S., Liang, C. W., Liao, I. C., Chang, Y. M., Wang, J. C., Tsao, C. F., Yu, S. C. & Huang, H. Y., Jan 1 2019, In : Histopathology.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Mutation
Histology
Myogenin
Mediastinum

The fungus-derived retinoprotectant theissenolactone C improves glaucoma-like injury mediated by MMP-9 inhibition

Lin, F. L., Cheng, Y. W., Yu, M., Ho, J. D., Kuo, Y. C., Chiou, G. C. Y., Chang, H. M., Lee, T. H. & Hsiao, G., Mar 15 2019, In : Phytomedicine. 56, p. 207-214 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 9
Glaucoma
Reperfusion Injury
Interleukin-1
Chemokine CCL2

The germ-free mice monocolonization with Bacteroides fragilis improves azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer

Lee, Y. P., Chiu, C. C., Lin, T. J., Hung, S. W., Huang, W. C., Chiu, C. F., Huang, Y. T., Chen, Y. H., Chen, T. H. & Chuang, H. L., Jan 1 2019, In : Immunopharmacology and Immunotoxicology.

Research output: Contribution to journalArticle

Azoxymethane
Bacteroides fragilis
Dextran Sulfate
Colitis
Colorectal Neoplasms

The importance of sleep for governmental sectors, general population and industry – Asia–Pacific Economic Cooperation (APEC) Sleep Technology Agenda

Chiang, R. P. Y., Lin, C. F., Li, Y. C. J. & Hsu, M. H., Feb 1 2019, In : Sleep Medicine Reviews. 43, p. 135-136 2 p.

Research output: Contribution to journalLetter

Industry
Sleep
Economics
Technology
Population
6 Citations (Scopus)

The incidence of fatal breast cancer measures the increased effectiveness of therapy in women participating in mammography screening

Tabár, L., Dean, P. B., Chen, T. H. H., Yen, A. M. F., Chen, S. L. S., Fann, J. C. Y., Chiu, S. Y. H., Ku, M. M. S., Wu, W. Y. Y., Hsu, C. Y., Chen, Y. C., Beckmann, K., Smith, R. A. & Duffy, S. W., Feb 15 2019, In : Cancer. 125, 4, p. 515-523 9 p.

Research output: Contribution to journalArticle

Open Access
Mammography
Breast Neoplasms
Incidence
Therapeutics
Confidence Intervals
2 Citations (Scopus)
Hydrogel
Stem cells
Hydrogels
Skin
Composite materials

The potential of the three-dimensional printed titanium mesh implant for cranioplasty surgery applications: Biomechanical behaviors and surface properties

Huang, M. T., Juan, P. K., Chen, S. Y., Wu, C. J., Wen, S. C., Cho, Y. C., Huang, M. S., Chou, H. H. & Ou, K. L., Apr 1 2019, In : Materials Science and Engineering C. 97, p. 412-419 8 p.

Research output: Contribution to journalArticle

Pore structure
Titanium
surgery
Surgery
surface properties

The protein corona suppresses the cytotoxic and pro-inflammatory response in lung epithelial cells and macrophages upon exposure to nanosilica

Leibe, R., Hsiao, I-L., Fritsch-Decker, S., Kielmeier, U., Wagbo, A. M., Voss, B., Schmidt, A., Hessman, S. D., Duschl, A., Oostingh, G. J., Diabaté, S. & Weiss, C., Jan 1 2019, In : Archives of Toxicology.

Research output: Contribution to journalArticle

Macrophages
Epithelial Cells
Lung
Cytotoxicity
Toxicity

Therapeutic Targeting of Non-oncogene Dependencies in High-risk Neuroblastoma

Huang, C-T., Hsieh, C-H., Lee, W-C., Liu, Y-L., Yang, T-S., Hsu, W-M., Oyang, Y-J., Huang, H-C. & Juan, H-F., Apr 5 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research.

Research output: Contribution to journalArticle

Neuroblastoma
Niclosamide
NM23 Nucleoside Diphosphate Kinases
Therapeutics
Drug Repositioning
1 Citation (Scopus)

The relationship between health literacy and perceived shared decision making in patients with breast cancer

Shen, H. N., Lin, C. C., Hoffmann, T., Tsai, C. Y., Hou, W. H. & Kuo, K. N., Feb 1 2019, In : Patient Education and Counseling. 102, 2, p. 360-366 7 p.

Research output: Contribution to journalArticle

Health Literacy
Decision Making
Breast Neoplasms
Education
R388

The role of nanofiltration in the pathogen safety of biologicals: an update

Inouye, M. & Burnouf, T. P. R., 2019, In : Current Nanoscience.

Research output: Contribution to journalArticle

Nanofiltration
Pathogens
Viruses
Technology
Safety
Finite Element Analysis
finite element analysis
Bone
bones
Finite element method

The therapeutic effect of aucubin-supplemented hyaluronic acid on interleukin-1beta-stimulated human articular chondrocytes

Huang, T. L., Yang, S. H., Chen, Y. R., Liao, J. Y., Tang, Y. & Yang, K. C., Feb 1 2019, In : Phytomedicine. 53, p. 1-8 8 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Hyaluronic Acid
Chondrocytes
Interleukin-1beta
Joints

The Use of Wearable Sensors for the Movement Assessment on Muscle Contraction Sequences in Post-Stroke Patients during Sit-to-Stand

Hsu, W. C., Chang, C. C., Lin, Y. J., Yang, F. C., Lin, L. F. & Chou, K. N., Feb 1 2019, In : Sensors (Switzerland). 19, 3, 657.

Research output: Contribution to journalArticle

Open Access
muscular function
Muscle Contraction
strokes
Muscle
Stroke

The value of MR T2* measurements in normal and osteoarthritic knee cartilage: effects of age, sex, and location

Tsai, P. H., Wong, C. C., Chan, W. P. & Lu, T. W., Jan 1 2019, (Accepted/In press) In : European Radiology.

Research output: Contribution to journalArticle

Cartilage
Knee
Thigh
Osteoarthritis
Weight-Bearing

Three-dimensional spherical gelatin bubble-based scaffold improves the myotube formation of H9c2 myoblasts

Mei, C., Chao, C. W., Lin, C. W., Li, S. T., Wu, K. H., Yang, K. C. & Yu, J., Jan 1 2019, (Accepted/In press) In : Biotechnology and Bioengineering.

Research output: Contribution to journalArticle

Myoblasts
Skeletal Muscle Fibers
Gelatin
Scaffolds
Substrates

Thymectomy in patients with myasthenia gravis increases the risk of autoimmune rheumatic diseases: a nationwide cohort study

Chang, C-C., Lin, T-M., Chang, Y-S., Chen, W-S., Sheu, J-J., Chen, Y-H. & Chen, J-H., Jan 1 2019, In : Rheumatology. 58, 1, p. 135-143 9 p.

Research output: Contribution to journalArticle

Thymectomy
Myasthenia Gravis
Rheumatic Diseases
Autoimmune Diseases
Cohort Studies

Tolerability of rifapentine-based regimens in latent tuberculosis infection treatment in the elderly

Chan, P. C., Lee, P. H., Lu, M. J., Huang, Y. C., Feng, T. Y., Chen, W. W., Lee, C. C., Huang, Y. F. & Chiang, C. Y., Mar 1 2019, In : The European respiratory journal. 53, 3

Research output: Contribution to journalLetter

Open Access
rifapentine
Latent Tuberculosis
Therapeutics

Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo

Hsu, Y. H., Chuang, H. C., Lee, Y. H., Lin, Y. F., Chen, Y. J., Hsiao, T. C., Wu, M. Y. & Chiu, H. W., May 1 2019, In : Free Radical Biology and Medicine. 135, p. 235-244 10 p.

Research output: Contribution to journalArticle

Open Access
Particulate Matter
Autophagy
Air Pollution
Air pollution
Kidney
Deaf-Blind Disorders
Risk-Taking
Observational Studies
Police
Logistic Models

Treatment outcomes for multidrug-resistant tuberculosis in Eastern Taiwan

Lin, C. B., Sun, H. C., Chiang, C. Y., Wu, C. W., Chou, H. W., Tang, T. Q. & Lee, J. J., Jan 1 2019, In : Tzu Chi Medical Journal. 31, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Open Access
Multidrug-Resistant Tuberculosis
Taiwan
Therapeutics
Quality of Health Care
Lost to Follow-Up
international law
Genes
stakeholder
Population
ability
Dental Pulp
p38 Mitogen-Activated Protein Kinases
Dentin
Magnetic Fields
Stem Cells

Use of lipid-lowering agents is not associated with improved outcomes for tuberculosis patients on standard-course therapy: A population-based cohort study

Chen, Y. T., Kuo, S. C., Chao, P. W. & Chang, Y. Y., Jan 1 2019, In : PLoS One. 14, 1, e0210479.

Research output: Contribution to journalArticle

antilipemic agents
Fibric Acids
Hydroxymethylglutaryl-CoA Reductase Inhibitors
cohort studies
tuberculosis

Using artificial neural network to predict functional recovery of patients treated by intravenous thrombolysis in acute ischemic stroke

Chiu, H. W., Huang, Y. T. & Cheng, C. A., Jan 1 2019, In : IFMBE Proceedings. 68, 1, p. 331-334 4 p.

Research output: Contribution to journalConference article

Neural networks
Recovery
Emergency rooms
Neurons
Medicine
Schizophrenia
Appointments and Schedules
Disabled Persons
Cognition
Taiwan

Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study

Chou, Y. C., You, S. L., Bai, C. H., Liao, Y. C., Wei, C. Y. & Sun, C. A., Jan 1 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Open Access
Apolipoproteins
Apolipoproteins B
Type 2 Diabetes Mellitus
Cohort Studies
Apolipoprotein A-I

Validation of the World Health Organization Disability Assessment Schedule 2.0 in adults with spinal cord injury in Taiwan: a psychometric study

Chiu, T. Y., Finger, M. E., Fellinghauer, C. S., Escorpizo, R., Chi, W. C., Liou, T. H. & Yen, C. F., Jan 1 2019, (Accepted/In press) In : Spinal Cord.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Taiwan
Psychometrics
Appointments and Schedules
Statistical Factor Analysis
Reproducibility of Results
Language
Psychometrics
Taiwan
Statistical Factor Analysis

Weak Coupling Between Intracellular Feedback Loops Explains Dissociation of Clock Gene Dynamics

Schmal, C., Ono, D., Myung, J., Pett, J. P., Honma, S., Honma, K-I., Herzel, H. & Tokuda, I. T., Jan 1 2019, In : bioRxiv.

Research output: Contribution to journalArticle

Genes
Circadian Clocks
Circadian Rhythm
Culture Media
Gene Expression