Find Research Outputs

2018
2 Citations

Development of a general method for quantifying IgG-based therapeutic monoclonal antibodies in human plasma using protein G purification coupled with a two internal standard calibration strategy using LC-MS/MS

Chiu, H. H., Liao, H. W., Shao, Y. Y., Lu, Y. S., Lin, C. H., Tsai, I. L. & Kuo, C. H., Jan 1 2018, (Accepted/In press) In : Analytica Chimica Acta.

Research output: Contribution to journalArticle

Calibration
antibody
Purification
purification
Blood Proteins

Development of computer aids ASPECTS system for acute ischemic stroke patient: A preliminary study

Su, J. L., Chan, L. & Huang, S. Y., Jan 1 2018, 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences - ICIBEL 2017 in conjunction with APCMBE 2017. Springer Verlag, Vol. 67. p. 203-207 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tomography
Computer systems
Median filters
Adaptive filters
Autocorrelation
Nanocomposites
Chitosan
Tissue Engineering
Bone and Bones
Hydrogels
2 Citations

Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia

Yeh, C. H., Hsieh, L. P., Lin, M. C., Wei, T. S., Lin, H. C., Chang, C. C. & Hsing, C. H., Jan 1 2018, In : PLoS One. 13, 1, e0191070.

Research output: Contribution to journalArticle

dexmedetomidine
Anhedonia
Dexmedetomidine
Illness Behavior
lipopolysaccharides

Dextromethorphan Attenuates NADPH Oxidase-regulated GSK-3β and NF-κB Activation and Reduces Nitric Oxide Production in Group A Streptococcal Infection

Chen, C-L., Cheng, M-H., Kuo, C-F., Cheng, Y-L., Li, M-H., Chang, C-P., Wu, J-J., Anderson, R., Wang, S., Tsai, P-J., Liu, C-C. & Lin, Y-S., Mar 26 2018, In : Antimicrobial Agents and Chemotherapy.

Research output: Contribution to journalArticle

Dextromethorphan
Glycogen Synthase Kinases
Streptococcal Infections
NADPH Oxidase
Streptococcus

Diagnostic consistency and interchangeability of schizophrenic disorders and bipolar disorders: A 7-year follow-up study

Hung, Y. N., Yang, S. Y., Kuo, C. J. & Lin, S. K., Mar 1 2018, In : Psychiatry and Clinical Neurosciences. 72, 3, p. 180-188 9 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Schizophrenia
Psychotic Disorders
Mental Disorders
Psychiatry
1 Citations

Diesel exhaust particles up-regulate interleukin-17A expression via ROS/NF-κB in airway epithelium

Weng, C. M., Lee, M. J., He, J. R., Chao, M. W., Wang, C. H. & Kuo, H. P., May 1 2018, In : Biochemical Pharmacology. 151, p. 1-8 8 p.

Research output: Contribution to journalArticle

Vehicle Emissions
Interleukin-17
Up-Regulation
Epithelium
Asthma

Die Wirksamkeit einer neuen Nagelspange für die Behandlung von eingewachsenen Nägeln

Liu, C. W. & Huang, Y-C., Apr 1 2018, In : JDDG - Journal of the German Society of Dermatology. 16, 4, p. 417-425 9 p.

Research output: Contribution to journalArticle

Physicians
Warfare

Difference between observed and predicted glycated hemoglobin at baseline and treatment response to vildagliptin-based dual oral therapy in patients with type 2 diabetes

Wang, J. S., Hung, Y. J., Lu, Y. C., Tsai, C. L., Yang, W. S., Lee, T. I., Hsiao, Y. C. & Sheu, W. H. H., Apr 1 2018, In : Diabetes Research and Clinical Practice. 138, p. 119-127 9 p.

Research output: Contribution to journalArticle

Glycosylated Hemoglobin A
Type 2 Diabetes Mellitus
Fasting
Glucose
Therapeutics

Differences between COPD patients and their families regarding willingness toward life-sustaining treatments

Chen, T. R., Hu, W. Y., Chiu, T. Y. & Kuo, H. P., Jan 1 2018, (Accepted/In press) In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Therapeutics
Medical Futility
Persistent Vegetative State
Noninvasive Ventilation
1 Citations

Differential Family Experience of Palliative Sedation Therapy in Specialized Palliative or Critical Care Units

Shen, H. S., Chen, S. Y., Cheung, D. S. T., Wang, S. Y., Lee, J. J. & Lin, C-C., Jan 1 2018, (Accepted/In press) In : Journal of Pain and Symptom Management.

Research output: Contribution to journalArticle

Critical Care
Palliative Care
Grief
Terminally Ill
Intensive Care Units

Diffusion tensor-derived properties of benign oligemia, true “at risk” Penumbra, and infarct core during the first three hours of stroke onset: A rat model

Chiu, F. Y., Kuo, D. P., Chen, Y. C., Kao, Y. C., Chung, H. W. & Chen, C. Y., Nov 1 2018, In : Korean Journal of Radiology. 19, 6, p. 1161-1171 11 p.

Research output: Contribution to journalArticle

Diffusion Tensor Imaging
Anisotropy
Middle Cerebral Artery Infarction
Stroke
TP 7

Digoxin and amiodarone on the risk of ischemic stroke in atrial fibrillation: An observational study

Lai, K. C., Chen, S. J., Lin, C. S., Yang, F. C., Lin, C. L., Hsu, C. W., Huang, W. C. & Kao, C. H., May 7 2018, In : Frontiers in Pharmacology. 9, MAY, 448.

Research output: Contribution to journalArticle

Amiodarone
Digoxin
Atrial Fibrillation
Observational Studies
Stroke
3 Citations

Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression

Wang, Y. C., Wu, D. W., Wu, T. C., Wang, L., Chen, C. Y. & Lee, H., Jan 11 2018, In : International Journal of Biological Sciences. 14, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

src Homology Domains
adenocarcinoma
Phosphoric Monoester Hydrolases
Epidermal Growth Factor Receptor
phosphatase
2 Citations

Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities

Chao, S. W., Chen, L. C., Yu, C. C., Liu, C. Y., Lin, T. E., Guh, J. H., Wang, C. Y., Chen, C. Y., Hsu, K. C. & Huang, W. J., Jan 1 2018, In : European Journal of Medicinal Chemistry. 143, p. 792-805 14 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Derivatives
Carbon
Molecular Docking Simulation
Cutaneous T-Cell Lymphoma
5 Citations

Discovery of enzymes for toluene synthesis from anoxic microbial communities

Beller, H. R., Rodrigues, A. V., Zargar, K., Wu, Y. W., Saini, A. K., Saville, R. M., Pereira, J. H., Adams, P. D., Tringe, S. G., Petzold, C. J. & Keasling, J. D., May 1 2018, In : Nature Chemical Biology. 14, 5, p. 451-457 7 p.

Research output: Contribution to journalArticle

Toluene
Enzymes
Aromatic Hydrocarbons
Metagenomics
S-Adenosylmethionine
1 Citations

Diseases of the pancreas and suicide mortality: A nationwide nested case-control study among patients with mental health disorders in Taiwan

Chen, H. M., Chen, V. C. H., Wang, T. N., Lu, M. L., Huang, Y. C., Dewey, M. E., Lee, J. K. W. & Tsai, C. P., Jan 1 2018, In : General Hospital Psychiatry. 50, p. 45-50 6 p.

Research output: Contribution to journalArticle

Taiwan
Mental Disorders
Suicide
Case-Control Studies
Pancreas
1 Citations

Disrupted neural variability during propofol-induced sedation and unconsciousness

Huang, Z., Zhang, J., Wu, J., Liu, X., Xu, J., Zhang, J., Qin, P., Dai, R., Yang, Z., Mao, Y., Hudetz, A. G. & Northoff, G., Nov 1 2018, In : Human Brain Mapping. 39, 11, p. 4533-4544 12 p.

Research output: Contribution to journalArticle

Unconsciousness
Propofol
Wakefulness
Anesthesia
Consciousness
1 Citations

Disrupted relationship between “resting state” connectivity and task-evoked activity during social perception in schizophrenia

Ebisch, S. J. H., Gallese, V., Salone, A., Martinotti, G., di Iorio, G., Mantini, D., Perrucci, M. G., Romani, G. L., Di Giannantonio, M. & Northoff, G., Mar 1 2018, In : Schizophrenia Research. 193, p. 370-376 7 p.

Research output: Contribution to journalArticle

Social Perception
Schizophrenia
Gyrus Cinguli
Healthy Volunteers
Prefrontal Cortex
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Prostatic Neoplasms
Genes
Castration
1 Citations

Dissociated resting-state functional networks between the dream recall frequency and REM sleep percentage

Zou, Q., Zhou, S., Xu, J., Su, Z., Li, Y., Ma, Y., Sun, H., Wu, C. W. & Gao, J. H., Jul 1 2018, In : NeuroImage. 174, p. 248-256 9 p.

Research output: Contribution to journalArticle

REM Sleep
Sleep
Cerebellum
Functional Neuroimaging
Polysomnography
1 Citations

Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors

Liew, P. L., Huang, R. L., Weng, Y. C., Fang, C. L., Hui-Ming Huang, T. & Lai, H. C., Jul 15 2018, In : International Journal of Cancer. 143, 2, p. 355-367 13 p.

Research output: Contribution to journalArticle

Mucinous Adenocarcinoma
Proteasome Inhibitors
Methylation
Gastrointestinal Neoplasms
Ovarian epithelial cancer

Distribution, habitat, and conservation status of the near-threatened Japanese paradise-flycatcher (Terpsiphone atrocaudata periophthalmica) on lanyu, Taiwan

Späth, T., Bai, M-L., Severinghaus, L. L. & Walther, B. A., 2018, In : Avian Conservation and Ecology. 13, 1

Research output: Contribution to journalArticle

conservation status
subspecies
Taiwan
species conservation
population size
DNA Primase
G2 Phase Cell Cycle Checkpoints
Estrogens
Breast Neoplasms
Peptides

Do 5α-reductase inhibitors prevent secondary benign prostate hyperplasia-related urinary retention?

Lu, C. F., Chen, C. Y., Lee, L. M., Lin, K. H., Lin, Y. W., Hsiao, C. H. & Wen, Y. C., Mar 1 2018, In : Urological Science. 29, 2, p. 86-90 5 p.

Research output: Contribution to journalArticle

Urinary Retention
Hyperplasia
Prostate
Oxidoreductases
International Classification of Diseases
Rib Fractures
Meta-Analysis
Confidence Intervals
Length of Stay
Odds Ratio
Hydroxymethylglutaryl-CoA Reductase Inhibitors
angiotensins
Angiotensin Receptors
case-control studies
Angiotensin-Converting Enzyme Inhibitors

Dopamine receptor D2 genetic variations is associated with the risk and clinicopathological variables of urothelial cell carcinoma in a taiwanese population

Tung, M. C., Wen, Y. C., Wang, S. S., Lin, Y. W., Liu, Y. C., Yang, S. F. & Chien, M. H., Jul 30 2018, In : International Journal of Medical Sciences. 15, 11, p. 1187-1193 7 p.

Research output: Contribution to journalArticle

Dopamine D2 Receptors
Dopamine Receptors
Carcinoma
Population
Odds Ratio
Pharmacokinetics
Metabolites
Hepatitis B
Rats
Urine
Attempted Suicide
Stillbirth
Spontaneous Abortion
Case-Control Studies
Pregnancy
Plasmapheresis
Hypertriglyceridemia
Pancreatitis
Triglycerides
Therapeutics
Dipeptidyl Peptidase 4
Apigenin
Gastropoda
Epidermal Growth Factor Receptor
Lung Neoplasms
1 Citations
Catenins
Neoplastic Stem Cells
Diterpenes
beta Catenin
Liver Neoplasms
7 Citations

Drug release and antioxidant/antibacterial activities of silymarin-zein nanoparticle/bacterial cellulose nanofiber composite films

Tsai, Y. H., Yang, Y. N., Ho, Y. C., Tsai, M. L. & Mi, F. L., Jan 15 2018, In : Carbohydrate Polymers. 180, p. 286-296 11 p.

Research output: Contribution to journalArticle

Zein
Silymarin
Composite films
Nanofibers
Antioxidants

DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ERBB signaling

Liao, W. C., Liao, C. K., Tsai, Y. H., Tseng, T. J., Chuang, L. C., Lan, C. T., Chang, H. M. & Liu, C. H., Jun 1 2018, In : PloS one. 13, 6, e0198364.

Research output: Contribution to journalArticle

Racemases and Epimerases
Dermatan Sulfate
heparin
Glioma
growth factors
1 Citations

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Autophagy
Urinary Bladder Neoplasms
Cell Death
Therapeutics
Clustered Regularly Interspaced Short Palindromic Repeats
5 Citations

Dual Stimuli-Responsive Nucleobase-Functionalized Polymeric Systems as Efficient Tools for Manipulating Micellar Self-Assembly Behavior

Gebeyehu, B. T., Huang, S. Y., Lee, A. W., Chen, J. K., Lai, J. Y., Lee, D. J. & Cheng, C. C., Feb 13 2018, In : Macromolecules. 51, 3, p. 1189-1197 9 p.

Research output: Contribution to journalArticle

Micelles
Self assembly
Uracil
Photoreactivity
Controlled drug delivery
1 Citations
Intracytoplasmic Sperm Injections
Gonadotropin-Releasing Hormone
Oocytes
Meta-Analysis
Pregnancy Rate

Dynamic Cerebral Autoregulation Is an Independent Functional Outcome Predictor of Mild Acute Ischemic Stroke

Chi, N. F., Hu, H. H., Wang, C. Y., Chan, L., Peng, C. K., Novak, V. & Hu, C. J., Nov 1 2018, In : Stroke. 49, 11, p. 2605-2611 7 p.

Research output: Contribution to journalArticle

Homeostasis
Stroke
Infarction
Arterial Pressure
ROC Curve

Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein-treated endothelial progenitor cells: a novel index for the prediction of HDL functionality

Shih, C. M., Lin, F. Y., Yeh, J. S., Lin, Y. W., Loh, S. H., Tsao, N. W., Nakagami, H., Morishita, R., Sawamura, T., Li, C. Y., Lin, C. Y. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Translational Research.

Research output: Contribution to journalArticle

Endothelial cells
HDL Lipoproteins
Assays
Dyslipidemias
Atherosclerosis
1 Citations

E4BP4 inhibits AngII-induced apoptosis in H9c2 cardiomyoblasts by activating the PI3K-Akt pathway and promoting calcium uptake

Chen, B. C., Shibu, M. A., Kuo, C. H., Shen, C. Y., Chang-Lee, S. N., Lai, C. H., Chen, R. J., Yao, C. H., Viswanadha, V. P., Liu, J. S., Chen, W. K. & Huang, C. Y., Jan 1 2018, (Accepted/In press) In : Experimental Cell Research.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Angiotensin II
Apoptosis
Calcium
Insulin-Like Growth Factor II
Health Knowledge, Attitudes, Practice
Dentists
Taiwan
General Practice
Pediatricians

Editorial: The janus face of language: Where are the emotions in words and where are the words in emotions?

Herbert, C., Ethofer, T., Fallgatter, A. J., Walla, P. & Northoff, G., May 17 2018, In : Frontiers in Psychology. 9, MAY, 650.

Research output: Contribution to journalEditorial

Emotions
Language

Effectively reducing reagent concentrations for electrochemical reactions in aqueous solutions using plasmon-activated water

Yang, C-P., Fang, S-U., Yang, K-H., Tsai, H-Y. & Liu, Y-C., 2018, In : Journal of Electroanalytical Chemistry. 818, p. 44-50 7 p.

Research output: Contribution to journalArticle

Deionized water
Water
Electrolytes
Hydrogen
Oxygen
5 Citations

Effectiveness and Safety of Standard- and Low-Dose Rivaroxaban in Asians With Atrial Fibrillation

Lin, Y. C., Chien, S. C., Hsieh, Y. C., Shih, C. M., Lin, F. Y., Tsao, N. W., Chen, C. W., Kao, Y. T., Chiang, K. H., Chen, W. T., Chien, L. N. & Huang, C. Y., Jul 31 2018, In : Journal of the American College of Cardiology. 72, 5, p. 477-485 9 p.

Research output: Contribution to journalArticle

Atrial Fibrillation
Safety
Hemorrhage
Myocardial Infarction
Rivaroxaban

Effectiveness of executive function training on mental set shifting, working memory and inhibition in healthy older adults: A double-blind randomized controlled trials

Chiu, H. L., Chan, P. T., Kao, C. C., Chu, H., Chang, P. C., Hsiao, S. T. S., Liu, D., Chang, W. C. & Chou, K. R., Jan 1 2018, (Accepted/In press) In : Journal of Advanced Nursing.

Research output: Contribution to journalArticle

Executive Function
Short-Term Memory
Randomized Controlled Trials
Cognition
Inhibition (Psychology)

Effectiveness of strontium ranelate in the treatment of rat model of legg-calve-perthes disease

Chen, Y. P., Tan, A., Ho, W. P., Chuang, T. Y., Chen, W. C. & Chen, C. H., Jul 1 2018, In : Indian Journal of Orthopaedics. 52, 4, p. 380-386 7 p.

Research output: Contribution to journalArticle

strontium ranelate
Legg-Calve-Perthes Disease
Thigh
Osteonecrosis
Bone Regeneration
3 Citations

Effective reduction of water molecules' interaction for efficient water evaporation in desalination

Chen, H. C., Chen, Y. R., Yang, K. H., Yang, C. P., Tung, K. L., Lee, M. J., Shih, J. H. & Liu, Y. C., Jun 15 2018, In : Desalination. 436, p. 91-97 7 p.

Research output: Contribution to journalArticle

Desalination
desalination
Evaporation
evaporation
Molecules

Effective Sirolimus Treatment for Refractory Spindle Cell Haemangioma

Ho, C. B., Hsieh, K., Chen, W. Y., Lin, Y. T., Chiou, J. F., Lee, H. L. & Shiah, H. S., May 11 2018, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Sirolimus
Hemangioma
Blood Vessels
Enchondromatosis
Therapeutics

Effect of (Ti, Al)N Nanostructured Arc-Coatings on Wear and Corrosion Properties of 4340 Alloy Steel

Hsu, C-H., Lin, C-K., Huang, W-C. & Lai, D-W., Apr 1 2018, In : Journal of Nanoscience and Nanotechnology. 18, 4, p. 2823-2829 7 p.

Research output: Contribution to journalArticle

Corrosion
Steel
Friction
Technology