Find Research Outputs

2018

A new niclosamide derivatives-B17 can inhibit urological cancers growth through apoptosis-related pathway

Wu, C-L., Chen, C-L., Huang, H-S. & Yu, D-S., Jun 28 2018, In : Cancer Medicine.

Research output: Contribution to journalArticle

Niclosamide
Urologic Neoplasms
Apoptosis
Growth
Control Groups

Angiotensin 1-7 modulates electrophysiological characteristics and calcium homoeostasis in pulmonary veins cardiomyocytes via MAS/PI3K/eNOS signalling pathway

Lu, Y. Y., Wu, W. S., Lin, Y. K., Cheng, C. C., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : European Journal of Clinical Investigation. 48, 1, p. e12854

Research output: Contribution to journalArticle

Pulmonary Veins
Phosphatidylinositol 3-Kinases
Cardiac Myocytes
Homeostasis
Calcium

An innovative α-calcium sulfate hemihydrate bioceramic as a potential bone graft substitute

Hsu, H. J., Waris, R. A., Ruslin, M., Lin, Y. H., Chen, C. S. & Ou, K. L., 2018, In : Journal of the American Ceramic Society.

Research output: Contribution to journalArticle

Calcium Sulfate
Bioceramics
Grafts
Calcium
Bone

An interesting phenomenon in immigrant spouses and elderly suicides in Taiwan

Lai, Y. C., Chen, I. H., Miao, N. F., Hsiao, Y. L. & Li, H. C., Jan 1 2018, In : Archives of Gerontology and Geriatrics. 74, p. 128-132 5 p.

Research output: Contribution to journalArticle

Spouses
Taiwan
spouse
Suicide
suicide
2 Citations

An Intestinal "transformers"-like Nanocarrier System for Enhancing the Oral Bioavailability of Poorly Water-Soluble Drugs

Chuang, E. Y., Lin, K. J., Huang, T. Y., Chen, H. L., Miao, Y. B., Lin, P. Y., Chen, C. T., Juang, J. H. & Sung, H. W., Jul 24 2018, In : ACS Nano. 12, 7, p. 6389-6397 9 p.

Research output: Contribution to journalArticle

bioavailability
Curcumin
transformers
drugs
Water

Annexin A2-mediated cancer progression and therapeutic resistance in nasopharyngeal carcinoma

Chen, C. Y., Lin, Y. S., Chen, C. H. & Chen, Y. J., Mar 29 2018, In : Journal of Biomedical Science. 25, 1, 30.

Research output: Contribution to journalArticle

Annexin A2
Annexins
Chemoradiotherapy
Neoplasms
Chemotherapy

Anodal and cathodal tDCS over the right frontal eye fields impacts spatial probability processing differently in pro- and anti-saccades

Tseng, P., Wang, M. C., Lo, Y. H. & Juan, C. H., Jun 27 2018, In : Frontiers in Neuroscience. 12, JUN, 421.

Research output: Contribution to journalArticle

Saccades
Frontal Lobe
Reaction Time
Transcranial Direct Current Stimulation
Spatial Processing

A Nonsurgical Solution: Jefferson (Burst) Fracture

Tay, S. Y., Li, C. W., Ko, C. H. & Chan, W. P., Sep 1 2018, In : American Journal of Medicine. 131, 9, p. 1061-1063 3 p.

Research output: Contribution to journalComment/debate

Bone
Experiments
Surgery
Fusion reactions
Genetic algorithms

An optimization study of screw position and number of screws for the fixation stability of a distal femoral locking compression plate using genetic algorithms

Hsu, C. C., Lee, C. H. & Hsu, S. M., Jul 6 2018, GECCO 2018 Companion - Proceedings of the 2018 Genetic and Evolutionary Computation Conference Companion. Association for Computing Machinery, Inc, p. 282-283 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fixation
Locking
Compression
Genetic algorithms
Genetic Algorithm

A Novel Approach to Fabricate Silicon Nanowire Field Effect Transistor for Biomolecule Sensing

Wu, C. C., Manga, Y. B., Hung, J. Y. & Yang, W. L., Jan 1 2018, AETA 2017 - Recent Advances in Electrical Engineering and Related Sciences - Theory and Application. Springer Verlag, Vol. 465. p. 250-257 8 p. (Lecture Notes in Electrical Engineering; vol. 465).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomolecules
Field effect transistors
Nanowires
Silicon
Drain current
1 Citations

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journalArticle

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., Mar 1 2018, In : Frontiers in Pharmacology. 9, MAR, 167.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Cell Death
Microtubules
Liver
Phosphorylation

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., Feb 1 2018, In : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

Research output: Contribution to journalArticle

GTP Cyclohydrolase
Missense Mutation
Dystonia
Genes
Leg

A novel printhead multiplexer data registration chip system with injection cavity design

Liou, J. C., Su, T. J., Lin, W. C. & Wen, W. J., Jan 1 2018, In : Microsystem Technologies. p. 1-6 6 p.

Research output: Contribution to journalArticle

controllers
chips
injection
channel noise
Controllers

A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease

Sun, C. Y., Wu, M. S., Lee, C. C., Chen, S. H., Lo, K. C. & Chen, Y. H., Dec 1 2018, In : Scientific Reports. 8, 1, 8085.

Research output: Contribution to journalArticle

Organic Anion Transporters
Nucleic Acid Regulatory Sequences
Chronic Renal Insufficiency
Single Nucleotide Polymorphism
Zebrafish

A Novel Thermal Bubble Valve Integrated Nanofluidic Preconcentrator for Highly Sensitive Biomarker Detection

Deng, C. Z., Fan, Y. J., Chung, P. S. & Sheen, H. J., Jul 27 2018, In : ACS Sensors. 3, 7, p. 1409-1415 7 p.

Research output: Contribution to journalArticle

Nanofluidics
biomarkers
Biomarkers
antigens
Antigens

Antiarrhythmic drug usage and prostate cancer: A population-based cohort study

Kao, L. T., Huang, C. C., Lin, H. C. & Huang, C. Y., Jan 1 2018, In : Asian Journal of Andrology. 20, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

Anti-Arrhythmia Agents
Prostatic Neoplasms
Cohort Studies
Potassium Channel Blockers
Sodium Channel Blockers
1 Citations

Antibacterial effects of chitosan/cationic peptide nanoparticles

Tamara, F. R., Lin, C., Mi, F. L. & Ho, Y. C., Feb 5 2018, In : Nanomaterials. 8, 2, 88.

Research output: Contribution to journalArticle

Chitosan
Protamines
Peptides
Nanoparticles
Bacillus cereus

Antimetastatic effects of Terminalia catappa leaf extracts on cervical cancer through the inhibition of matrix metalloprotein-9 and MAPK pathway

Lee, C. Y., Yang, S. F., Wang, P. H., Su, C. W., Hsu, H. F., Tsai, H. T. & Hsiao, Y. H., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Terminalia
Metalloproteins
Uterine Cervical Neoplasms
cancer
Cells
1 Citations

Antimetastatic potentials of salvianolic acid A on oral squamous cell carcinoma by targeting MMP-2 and the c-Raf/MEK/ERK pathway

Fang, C. Y., Wu, C. Z., Chen, P. N., Chang, Y. C., Chuang, C. Y., Lai, C. T., Yang, S. F. & Tsai, L. L., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases
targeting
Squamous Cell Carcinoma
matrix
1 Citations

Anti-Oxidative Effects of Melatonin Receptor Agonist and Omega-3 Polyunsaturated Fatty Acids in Neuronal SH-SY5Y Cells: Deciphering Synergic Effects on Anti-Depressant Mechanisms

Satyanarayanan, S. K., Shih, Y. H., Chien, Y. C., Huang, S. Y., Gałecki, P., Kasper, S., Chang, J. P. C. & Su, K. P., Feb 3 2018, (Accepted/In press) In : Molecular Neurobiology. p. 1-14 14 p.

Research output: Contribution to journalArticle

Melatonin Receptors
Omega-3 Fatty Acids
Unsaturated Fatty Acids
Eicosapentaenoic Acid
Fluoxetine
hemodialysis
fistula
Platelet Aggregation Inhibitors
Arteriovenous Fistula
case-control studies

Anti-thymic stromal lymphopoietin antibody suppresses airway remodeling in asthma through reduction of MMP and CTGF

Lin, S. C., Chou, H. C., Chen, C. M. & Chiang, B. L., Jan 1 2018, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Connective Tissue Growth Factor
Airway Remodeling
Matrix Metalloproteinases
Ovalbumin
Asthma

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

Dengue Virus
Tumor Necrosis Factor-alpha
Encephalitis
Virus Diseases
Dengue

Antrodia cinnamomea extract inhibits the proliferation of tamoxifen-resistant breast cancer cells through apoptosis and skp2/microRNAs pathway

Lin, Y. S., Lin, Y. Y., Yang, Y. H., Lin, C. L., Kuan, F. C., Lu, C. N., Chang, G. H., Tsai, M. S., Hsu, C. M., Yeh, R. A., Yang, P. R., Lee, I. Y., Shu, L. H., Cheng, Y. C., Liu, H. T., Lee, K. D., Chang, D. C. & Wu, C. Y., May 9 2018, In : BMC Complementary and Alternative Medicine. 18, 1, 152.

Research output: Contribution to journalArticle

Antrodia
S-Phase Kinase-Associated Proteins
Tamoxifen
MicroRNAs
Apoptosis
Dissecting Aneurysm
Arteries
Hemorrhage

An Unusual Rectal Mass

Wang, W. L., Chang, I. W. & Lee, C. T., Mar 1 2018, In : Gastroenterology. 154, 4, p. e10-e11

Research output: Contribution to journalComment/debate

A pan-genome-based machine learning approach for predicting antimicrobial resistance activities of the Escherichia coli strains

Her, H. L. & Wu, Y. W., Jul 1 2018, In : Bioinformatics. 34, 13, p. i89-i95

Research output: Contribution to journalArticle

Escherichia coli
Escherichia Coli
Learning systems
Machine Learning
Genome
1 Citations

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, A. B., O’Donnell, R., Semrad, T. J., Mack, P., Blanchard, S., Bahary, N., Jiang, Y., Yen, Y., Wright, J., Chen, H., Lenz, H. J. & Gandara, D. R., May 1 2018, In : Cancer Chemotherapy and Pharmacology. 81, 5, p. 957-963 7 p.

Research output: Contribution to journalArticle

Toxicity
Hepatocellular Carcinoma
Somatomedins
Liver Neoplasms
Peritonitis
4 Citations

A Population-Based Cohort Study on the Drug-Specific Effect of Statins on Sepsis Outcome

Lee, C. C., Lee, M. T. G., Hsu, T. C., Porta, L., Chang, S. S., Yo, C. H., Tsai, K. C. & Lee, M., Apr 1 2018, In : Chest. 153, 4, p. 805-815 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Sepsis
Cohort Studies
Simvastatin
Pharmaceutical Preparations
Earthquakes
Disasters
Survivors
Wounds and Injuries
Outpatients
4 Citations

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., Oct 15 2018, In : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Biosensing Techniques
Biosensors
DNA
Fabrication
4 Citations

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., Oct 15 2018, In : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Biosensing Techniques
Biosensors
DNA
Fabrication
3 Citations
olanzapine
Schizophrenia
Drug Monitoring
C-Peptide
Waist Circumference

Application of Ultrasound Image Tracking Algorithm for Real-Time Diaphragmatic Excursion Measurement

Kuo, C. Y., Chuang, H. C., Zhou, Y. L., Wu, Y. P., Wang, J. C., Kuo, C. C., Jeng, S. C., Kao, H. W., Huang, M. Y., Chiou, J. F. & Liao, A. H., Aug 1 2018, In : Journal of Medical and Biological Engineering. 38, 4, p. 678-684 7 p.

Research output: Contribution to journalArticle

Diaphragms
Ultrasonics
Freezing

Applications of cyclic peptide nanotubes (cPNTs)

Hsieh, W. H. & Liaw, J., Jan 1 2018, (Accepted/In press) In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

Peptide Nanotubes
nanotubes
cyclic peptides
Cyclic Peptides
drugs

Applications of machine learning in fatty live disease prediction

Mohaimenul Islam, M., Wu, C. C., Poly, T. N., Yang, H. C. & Li, Y. C., Jan 1 2018, Building Continents of Knowledge in Oceans of Data: The Future of Co-Created eHealth - Proceedings of MIE 2018. IOS Press, p. 166-170 5 p. (Studies in Health Technology and Informatics; vol. 247).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Liver
Learning systems
Liver Diseases
Fatty Liver
Logistic Models

Applying sequential pattern mining to investigate cerebrovascular health outpatients' re-visit patterns

Ou-Yang, C., Wulandari, C. P., Hariadi, R. A. R., Wang, H-C. & Chen, C., 2018, In : PeerJ. 6, p. e5183

Research output: Contribution to journalArticle

Marketing
Outpatients
Health
Radiology
Strategic planning
1 Citations

A prominent air pollutant, Indeno[1,2,3-cd]pyrene, enhances allergic lung inflammation via aryl hydrocarbon receptor

Wong, T. H., Lee, C. L., Su, H. H., Lee, C. L., Wu, C. C., Wang, C. C., Sheu, C. C., Lai, R. S., Leung, S. Y., Lin, C. C., Wei, Y. F., Wang, C. J., Lin, Y. C., Chen, H. L., Huang, M. S., Yen, J. H., Huang, S. K. & Suen, J. L., Dec 1 2018, In : Scientific Reports. 8, 1, 5198.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Air Pollutants
Polycyclic Aromatic Hydrocarbons
Pneumonia
Taiwan
Replacement Arthroplasties
Knee
Hip Replacement Arthroplasties
Joints
Quality of Life
Geriatric Assessment
Walking
Randomized Controlled Trials
Exercise
Waist-Hip Ratio

A rare cause of hematochezia after colonoscopy

Kao, W. Y., Cheng, T. & Chang, C. C., Jan 1 2018, (Accepted/In press) In : Digestive and Liver Disease.

Research output: Contribution to journalArticle

Gastrointestinal Hemorrhage
Colonoscopy

A Rare Complication of Recurrent Duodenal Ulcer

Lee, C. Y., Chen, M. Y. & Wang, W. Y., Sep 1 2018, In : Gastroenterology. 155, 3, p. e5-e6

Research output: Contribution to journalComment/debate

A rare Krukenberg tumor arising from a primary adenocarcinoma of the small intestine

An-Chieh Liu, A., Chen, C. H., Liu, W. M. & Chang, C-W., Jan 1 2018, (Accepted/In press) In : Taiwanese Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Krukenberg Tumor
Small Intestine
Adenocarcinoma
Ovary
Neoplasms
1 Citations

Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways

Chen, K. Y., Lin, J. A., Yao, H. Y., Hsu, A. C., Tai, Y. T., Chen, J. T., Hsieh, M. C., Shen, T. L., Hsu, R. Y., Wu, H. T., Wang, G. H., Ho, B. Y. & Chen, Y. P., Jan 1 2018, (Accepted/In press) In : Nutrition Research.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
1-Phosphatidylinositol 4-Kinase
Hepatocytes
Inflammation
Disease Progression

Arginine administration increases circulating endothelial progenitor cells and attenuates tissue injury in a mouse model of hind limb ischemia/reperfusion

Hsieh, K. F., Shih, J. M., Shih, Y. M., Pai, M. H. & Yeh, S. L., Nov 1 2018, In : Nutrition. 55-56, p. 29-35 7 p.

Research output: Contribution to journalArticle

Reperfusion
Arginine
Ischemia
Extremities
Wounds and Injuries
Obese Mice
High Fat Diet
Arginine
Ischemia
Extremities

Arthroprotective effects of Cf-02 sharing structural similarity with quercetin

Liu, F. C., Lu, J. W., Chien, C. Y., Huang, H. S., Lee, C. C., Lien, S. B., Lin, L. C., Chen, L. W., Ho, Y. J., Shen, M. C., Ho, L. J. & Lai, J. H., May 14 2018, In : International Journal of Molecular Sciences. 19, 5, 1453.

Research output: Contribution to journalArticle

Quercetin
Nitric oxide
Cartilage
Chondrocytes
arthritis
1 Citations

Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma

Weng, C. M., Wang, C. H., Lee, M. J., He, J. R., Huang, H. Y., Chao, M. W., Chung, K. F. & Kuo, H-P., Jan 1 2018, (Accepted/In press) In : Allergy: European Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticle

Vehicle Emissions
Aryl Hydrocarbon Receptors
Interleukin-17
Asthma
Epithelium