Find Research Outputs

2019

Hirsutanol A attenuates lipopolysaccharide-mediated matrix metalloproteinase 9 expression and cytokines production and improves endotoxemia-induced acute sickness behavior and acute lung injury

Jan, J. S., Yang, C. H., Wang, M. H., Lin, F. L., Yen, J. L., Hsieh, I., Khotimchenko, M., Lee, T. H. & Hsiao, G., Jun 17 2019, In : Marine Drugs. 17, 6, 360.

Research output: Contribution to journalArticle

Open Access
Illness Behavior
Endotoxemia
Acute Lung Injury
Matrix Metalloproteinase 9
Lipopolysaccharides

Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc

Lin, C. Y., Wang, B. J., Chen, B. C., Tseng, J. C., Jiang, S. S., Tsai, K. K., Shen, Y. Y., Yuh, C. H., Sie, Z. L., Wang, W. C., Kung, H. J. & Chuu, C. P., Nov 2019, In : Cancers. 11, 11, 1785.

Research output: Contribution to journalArticle

Open Access
Histone Demethylases
Prostatic Neoplasms
Prostate
Androgen Receptors
Cell Proliferation

HMGCS2 mediates ketone production and regulates the proliferation and metastasis of hepatocellular carcinoma

Wang, Y. H., Liu, C. L., Chiu, W. C., Twu, Y. C. & Liao, Y. J., Dec 2019, In : Cancers. 11, 12, 1876.

Research output: Contribution to journalArticle

Open Access
Hydroxymethylglutaryl-CoA Synthase
Ketones
Hepatocellular Carcinoma
Neoplasm Metastasis
Liver Neoplasms
1 Citation (Scopus)

HOGG1 rs1052133 Genotypes and Risk of Childhood Acute Lymphoblastic Leukemia in a Taiwanese Population

Hsu, P. C., Chen, C. C., Tzeng, H. E., Hsu, Y. N., Kuo, C. C., Lin, M. L., Chang, W. S., Wang, Y. C., Tsai, C. W., Pei, J. S. & Bau, DA. T., Jul 1 2019, In : In vivo (Athens, Greece). 33, 4, p. 1081-1086 6 p.

Research output: Contribution to journalArticle

Open Access
DNA Glycosylases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genotype
Population
Polymorphism
5 Citations (Scopus)

Homeostasis of glucose and lipid in non-alcoholic fatty liver disease

Chao, H. W., Chao, S. W., Lin, H., Ku, H. C. & Cheng, C. F., Jan 2 2019, In : International Journal of Molecular Sciences. 20, 2, 298.

Research output: Contribution to journalReview article

homeostasis
liver
glucose
Liver
Lipids

Homocysteine, rather than age of onset, is a better predictor for cognitive function in older adults with bipolar disorder

Chen, P-H., Liu, H-C., Lu, M-L., Chen, C-H., Chang, C-J., Chiu, W-C., Sun, I-W., Liu, S-I., Tsai, S-Y., Chiu, C-C. & Stewart, R., May 21 2019, In : International Journal of Geriatric Psychiatry.

Research output: Contribution to journalArticle

Homocysteine
Bipolar Disorder
Age of Onset
Cognition
Blood Vessels

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers

Chen, Y. F., Wang, Y. H., Lei, C. S., Changou, C. A., Davis, M. E. & Yen, Y., Oct 23 2019, In : Journal of Biomedical Science. 26, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
Camptothecin
Cyclodextrins
Polymers
Neoplasms
Nanoparticles
Losartan
Dilatation
Mutation
Fibrillin-1

How much do we know about constipation after surgery for anorectal malformation?

Chang, P. C. Y., Duh, Y. C., Fu, Y. W., Hsu, Y. J., Wei, C. H. & Huang, H., Jan 1 2019, In : Pediatrics and Neonatology.

Research output: Contribution to journalArticle

Open Access
Constipation
Laxatives
Anorectal Malformations
Weaning
Fistula
1 Citation (Scopus)

How Plastic Surgeons Value Professionalism: Using Q Methodology to Explore the Prioritization of Professionalism

Chiu, C. H., Pan, S. C. & Lin, Y. C., Nov 13 2019, In : Aesthetic Surgery Journal. 39, 12, p. 1412-1422 11 p.

Research output: Contribution to journalArticle

Medicine
Knowledge Management
Clinical Competence
Social Welfare
Esthetics
2 Citations (Scopus)

HSD3B1 gene polymorphism and female pattern hair loss in women with polycystic ovary syndrome

Tu, Y. A., Lin, S. J., Chen, P. L., Chou, C. H., Huang, C. C., Ho, H. N. & Chen, M. J., Aug 1 2019, In : Journal of the Formosan Medical Association. 118, 8, p. 1225-1231 7 p.

Research output: Contribution to journalArticle

Open Access
Polycystic Ovary Syndrome
Alopecia
Genes
Triglycerides
Body Mass Index

HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor

Hung, C. S., Huang, C. Y., Hsu, Y. W., Makondi, P. T., Chang, W. C., Chang, Y. J., Wang, J. Y. & Wei, P. L., Jan 1 2019, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

Polymorphism
Tumors
Colorectal Neoplasms
Single Nucleotide Polymorphism
Neoplasms

Human adipose-derived stem cell secreted extracellular matrix incorporated into electrospun poly(lactic-co-glycolic acid) nanofibrous dressing for enhancing wound healing

Tang, K. C., Yang, K. C., Lin, C. W., Chen, Y. K., Lu, T. Y., Chen, H. Y., Cheng, N. C. & Yu, J., Oct 1 2019, In : Polymers. 11, 10, 1609.

Research output: Contribution to journalArticle

Open Access
Stem cells
Acids
Skin
Electrospinning
Substrates
1 Citation (Scopus)

Human Factors in the Cybersecurity of Autonomous Vehicles: Trends in Current Research

Linkov, V., Zámečník, P., Havlíčková, D. & Pai, C-W., 2019, In : Frontiers in Psychology. 10, p. 995

Research output: Contribution to journalArticle

Computer Security
Research
Psychology
Research Personnel
Aptitude
1 Citation (Scopus)

Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer

Lu, H., Wang, C., Xue, L., Zhang, Q., Luh, F., Wang, J., Lin, T. G., Yen, Y. & Liu, X., Jan 1 2019, In : Journal of Oncology. 2019, 2316237.

Research output: Contribution to journalArticle

Open Access
Kinesin
Centromere
MicroRNAs
Breast Neoplasms
Survival Analysis
12 Citations (Scopus)

Human platelet lysate current standards and future developments

Henschler, R., Gabriel, C., Schallmoser, K., Burnouf, T. & Koh, M. B. C., Jan 1 2019, In : Transfusion.

Research output: Contribution to journalReview article

Blood Platelets
Mesenchymal Stromal Cells
Cell- and Tissue-Based Therapy
Safety
Education

Hurdle Poisson Regression Model for Identifying Factors Related to Noncompliance and Waiting Time for Confirmatory Diagnosis in Colorectal Cancer Screening

Jen, H. H., Wang, T. H., Chiu, H. M., Peng, S. M., Hsu, C. Y., Chiu, S. Y. H., Chen, S. L. S., Yen, A. M. F., Lee, Y. C., Chen, H. H. & Fann, J. C. Y., Jan 1 2019, In : International Journal of Technology Assessment in Health Care. 35, 2, p. 85-91 7 p.

Research output: Contribution to journalArticle

Early Detection of Cancer
Colorectal Neoplasms
Compliance
Colonoscopy
Urbanization
1 Citation (Scopus)

Hyperactive CREB signaling pathway involved in the pathogenesis of polycystic ovarian syndrome revealed by patient-specific induced pluripotent stem cell modeling

Huang, C. C., Chen, M. J., Lan, C. W., Wu, C. E., Huang, M. C., Kuo, H. C. & Ho, H. N., Jan 1 2019, In : Fertility and Sterility.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Granulosa Cells
Polycystic Ovary Syndrome
CREB-Binding Protein
DNA Methylation

Hyperhomocysteinemia Associated with Low Muscle Mass, Muscle Function in Elderly Hemodialysis Patients: An Analysis of Multiple Dialysis Centers

Wang, C. S., Wong, T. C., Duong, T. V., Su, C. T., Chen, H. H., Chen, T. H., Hsu, Y. H., Peng, S. J., Kuo, K. L., Liu, H. C., Lin, E. T., Feng, Y. W. & Yang, S. H., Jan 1 2019, In : BioMed Research International. 2019, 9276097.

Research output: Contribution to journalArticle

Open Access
Hyperhomocysteinemia
Dialysis
Renal Dialysis
Muscle
Muscles
Pregnancy
Cysts
Neoplasms
Granulosa Cells
Tumor Biomarkers
1 Citation (Scopus)

Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in Asians: A population-based cohort study and meta-analysis

Chen, C-H., Chen, C-B., Chang, C. J., Lin, Y. J., Wang, C-W., Chi, C-C., Lu, C-W., Chen, W-T., Pan, R-Y., Su, S-C., Hsu, L-A., Chang, Y-C., Yu, K-H., Wu, Y-J. J., Lin, K-M., Hung, S-I., Chen, S-M. & Chung, W-H., Jan 28 2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Allopurinol
Meta-Analysis
Hypersensitivity
Cohort Studies
Population
Brain Diseases
Hypoglycemic Agents
Stroke
Magnetic Resonance Imaging
Axons
3 Citations (Scopus)

Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology

Hung, P. F., Hong, T. M., Chang, C. C., Hung, C. L., Hsu, Y. L., Chang, Y. L., Wu, C. T., Chang, G. C., Chan, N. L., Yu, S. L., Yang, P. C. & Pan, S. H., Jan 6 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 5.

Research output: Contribution to journalArticle

Sumoylation
Gastropoda
Biological Science Disciplines
Biochemistry
Cell Biology

Identification and medical utilization of newly diagnosed panic disorder: A Nationwide case–control study

Chang, H. M., Pan, C. H., Chen, P. H., Chen, Y. L., Su, S. S., Tsai, S. Y., Chen, C. C. & Kuo, C. J., Oct 2019, In : Journal of Psychosomatic Research. 125, 109815.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Identification of baicalin from Bofutsushosan and Daisaikoto as a potent inducer of glucose uptake and modulator of insulin signaling-associated pathways

Kuo, Y. T., Lin, C. C., Kuo, H. T., Hung, J. H., Liu, C. H., Jassey, A., Yen, M. H., Wu, S. J. & Lin, L. T., Jan 2019, In : Journal of Food and Drug Analysis. 27

Research output: Contribution to journalArticle

insulin
Insulin
uptake mechanisms
Glucose
glucose
11 Citations (Scopus)

Identification of clathrin proteins by incorporating hyperparameter optimization in deep learning and PSSM profiles

Le, N. Q. K., Huynh, T. T., Yapp, E. K. Y. & Yeh, H. Y., Aug 1 2019, In : Computer Methods and Programs in Biomedicine. 177, p. 81-88 8 p.

Research output: Contribution to journalArticle

Position-Specific Scoring Matrices
Clathrin
Learning
Proteins
Neural networks
5 Citations (Scopus)

Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform

Lin, H. S., Huang, Y. L., Wang, Y. R., Hsiao, E., Hsu, T. A., Shiao, H. Y., Jiaang, W. T., Sampurna, B. P., Lin, K. H., Wu, M. S., Lai, G. M. & Yuh, C. H., Jun 1 2019, In : Cancers. 11, 6, 739.

Research output: Contribution to journalArticle

Open Access
Preclinical Drug Evaluations
Zebrafish
Liver Neoplasms
Hepatocellular Carcinoma
Inhibitory Concentration 50
4 Citations (Scopus)

Identification of potential biomarkers related to glioma survival by gene expression profile analysis

Hsu, J. B. K., Chang, T. H., Lee, G. A., Lee, T. Y. & Chen, C. Y., Mar 20 2019, In : BMC Medical Genomics. 11, 34.

Research output: Contribution to journalArticle

Open Access
Transcriptome
Glioma
Biomarkers
Survival
Genes

Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation

Wang, C. H., Hung, P. W., Chiang, C. W., Lombès, M., Chen, C. H., Lee, K. H., Lo, Y. C., Wu, M. H., Chang, W. C. & Lin, D. Y., Aug 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 8, p. 1282-1297 16 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Ubiquitin
Catenins
Aldosterone
Transcriptional Activation
1 Citation (Scopus)

Identification of withaferin a as a potential candidate for anti-cancer therapy in non-small cell lung cancer

Hsu, J. H. M., Chang, P. M. H., Cheng, T. S., Kuo, Y. L., Wu, A. T. H., Tran, T. H., Yang, Y. H., Chen, J. M., Tsai, Y. C., Chu, Y. S., Huang, T. H., Huang, C. Y. F. & Lai, J. M., Jul 1 2019, In : Cancers. 11, 7, 1003.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Neoplasms
Cisplatin
Therapeutics

Identifying SNAREs by Incorporating Deep Learning Architecture and Amino Acid Embedding Representation

Le, N. Q. K. & Huynh, T. T., Dec 10 2019, In : Frontiers in Physiology. 10, 1501.

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

iEnhancer-5Step: Identifying enhancers using hidden information of DNA sequences via Chou's 5-step rule and word embedding

Le, N. Q. K., Yapp, E. K. Y., Ho, Q. T., Nagasundaram, N., Ou, Y. Y. & Yeh, H. Y., Apr 15 2019, In : Analytical Biochemistry. 571, p. 53-61 9 p.

Research output: Contribution to journalArticle

DNA sequences
Natural Language Processing
Genomics
Computational Biology
Inflammatory Bowel Diseases

IEnhancer-ECNN: Identifying enhancers and their strength using ensembles of convolutional neural networks

Nguyen, Q. H., Nguyen-Vo, T. H., Le, N. Q. K., Do, T. T. T., Rahardja, S. & Nguyen, B. P., Dec 24 2019, In : BMC Genomics. 20, 951.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling

Pidugu, V. K., Wu, M. M., Yen, A. H., Pidugu, H. B., Chang, K. W., Liu, C. J. & Lee, T. C., Apr 25 2019, In : Oncogene. 38, 17, p. 3232-3247 16 p.

Research output: Contribution to journalArticle

Recycling
Squamous Cell Carcinoma
Neoplasm Metastasis
Neoplasms
Epithelial-Mesenchymal Transition
2 Citations (Scopus)

Imaging Biomarkers as Predictors for Breast Cancer Death

Wu, W. Y. Y., Tabar, L., Tot, T., Fann, C. Y., Yen, A. M. F., Chen, S. L. S., Chiu, S. Y. H., Ku, M. M. S., Hsu, C. Y., Beckmann, K. R., Smith, R. A., Duffy, S. W. & Chen, H. H., Jan 1 2019, In : Journal of Oncology. 2019, 2087983.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Breast Neoplasms
Phenotype
Neoplasms
Tumor Biomarkers

Immune effector monocyte–neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer

Hagerling, C., Gonzalez, H., Salari, K., Wang, C. Y., Lin, C., Robles, I., van Gogh, M., Dejmek, A., Jirström, K. & Werb, Z., Oct 22 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 43, p. 21704-21714 11 p.

Research output: Contribution to journalArticle

Open Access
Monocytes
Neutrophils
Breast Neoplasms
Neoplasms
Lung
1 Citation (Scopus)

Immunopathological effects of Agaricus blazei Murill polysaccharides against Schistosoma mansoni infection by Th1 and NK1 cells differentiation

Lin, M. H., Lee, K. M., Hsu, C. Y., Peng, S. Y., Lin, C. N., Chen, C. C., Fan, C. K. & Cheng, P. C., Aug 1 2019, In : International Immunopharmacology. 73, p. 502-514 13 p.

Research output: Contribution to journalArticle

Agaricus
Schistosomiasis mansoni
Th1 Cells
Polysaccharides
Cell Differentiation
16 Citations (Scopus)

iMotor-CNN: Identifying molecular functions of cytoskeleton motor proteins using 2D convolutional neural network via Chou's 5-step rule

Le, N. Q. K., Yapp, E. K. Y., Ou, Y. Y. & Yeh, H. Y., Jun 15 2019, In : Analytical Biochemistry. 575, p. 17-26 10 p.

Research output: Contribution to journalArticle

Cytoskeleton
Neural networks
Proteins
Molecular Motor Proteins
Learning

Impact of metformin use among tuberculosis close contacts with diabetes mellitus in a nationwide cohort study

Lee, M. C., Lee, C. H., Lee, M. R., Wang, J. Y. & Chen, S. M., Nov 6 2019, In : BMC Infectious Diseases. 19, 1, 936.

Research output: Contribution to journalArticle

Open Access
Metformin
Diabetes Mellitus
Tuberculosis
Cohort Studies
Insulin

Impact of oral potentially malignant disorder subtypes on all-cause and cause-specific mortality in males

Yen, A. M. F., Wang, S. T., Peng, B. Y., Cheng, Y. C., Siewchaisakul, P., Hsu, C. Y. & Chen, S. L. S., Apr 1 2019, In : Oral Diseases. 25, 3, p. 750-757 8 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Areca
Nuts
Mortality
Tobacco Products

Impact of overdiagnosis on long-term breast cancer survival

Fann, J. C. Y., Chang, K. J., Hsu, C. Y., Yen, A. M. F., Yu, C. P., Chen, S. L. S., Kuo, W. H., Tabár, L. & Chen, H. H., Mar 1 2019, In : Cancers. 11, 3, 325.

Research output: Contribution to journalArticle

Open Access
Mammography
Breast Neoplasms
Survival
Therapeutics
Medical Overuse

Impact of Percent Body Fat on All-Cause Mortality among Adequate Dialysis Patients with and without Insulin Resistance: A Multi-Center Prospective Cohort Study

Duong, T. V., Wong, T. C., Chen, H. H., Chen, T. H., Hsu, Y. H., Peng, S. J., Kuo, K. L., Liu, H. C., Lin, E. T. & Yang, S. H., Jun 1 2019, In : Nutrients. 11, 6, 1304.

Research output: Contribution to journalArticle

Open Access
dialysis
cohort studies
insulin resistance
body fat
Insulin Resistance

Impact of Renal Artery Stent-Graft Placement on Renal Function in Chronic Aortic Dissection

Kuo, T. T., Huang, C. Y., Chen, P. L., Chen, I. M. & Shih, C. C., Jul 1 2019, In : Journal of Vascular and Interventional Radiology. 30, 7, p. 979-986 8 p.

Research output: Contribution to journalArticle

Renal Artery
Stents
Dissection
Transplants
Kidney

Impact of socio-demographic factors, lifestyle and health status on nutritional status among the elderly in Taiwan

Poda, G. G., Hsu, C. Y., Rau, H. H. & Chao, J. C. J., Jan 1 2019, In : Nutrition Research and Practice. 13, 3, p. 222-229 8 p.

Research output: Contribution to journalArticle

Open Access
Nutritional Status
health status
Taiwan
Health Status
lifestyle

Impact of universal drug susceptibility testing and effective management of multidrug-resistant tuberculosis in Taiwan

Lee, P. H., Chan, P. C., Peng, Y. T., Chu, P. W., Wu, M. H., Jou, R., Yu, M. C., Lin, C. J., Huang, Y. W., Chien, S. T., Lee, J. J. & Chiang, C. Y., Apr 1 2019, In : PLoS One. 14, 4, e0214792.

Research output: Contribution to journalArticle

Open Access
Multidrug-Resistant Tuberculosis
Taiwan
tuberculosis
drugs
Testing
1 Citation (Scopus)

Impact of varying anatomic sites on advanced stage and survival of oral cancer: A 9-year prospective cohort of 27 717 cases

Su, W. W. Y., Su, C. W., Chang, D. C., Chuang, S. L., Chen, S. L. S., Hsu, C. Y., Yen, A. M. F., Chiu, S. Y. H., Fann, J. C. Y., Lee, Y. H., Jeng, Y. C., Lee, Y. C., Chiu, H. M., Chen, T. H. H., Wang, C. P. & Chen, M. K., Jan 1 2019, (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Mouth Neoplasms
Hard Palate
Mouth Floor
Oropharynx
Cheek
1 Citation (Scopus)

Impacts of in-cabin exposure to size-fractionated particulate matters and carbon monoxide on changes in heart rate variability for healthy public transit commuters

Tang, C. S., Wu, T. Y., Chuang, K. J., Chang, T. Y., Chuang, H. C., Lung, S. C. C. & Chang, L. T., Jul 1 2019, In : ATMOSPHERE. 10, 7, 409.

Research output: Contribution to journalArticle

Open Access
carbon monoxide
particulate matter
public
rate
exposure
3 Citations (Scopus)

Impaired prefrontal cortical dopamine release in schizophrenia during a cognitive task: A [11C]FLB 457 positron emission tomography study

Rao, N., Northoff, G., Tagore, A., Rusjan, P., Kenk, M., Wilson, A., Houle, S., Strafella, A., Remington, G. & Mizrahi, R., May 2019, In : Schizophrenia Bulletin. 45, 3, p. 670-679 10 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Dopamine
Schizophrenia
Prefrontal Cortex
Gyrus Cinguli

Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method

Chepyala, D., Kuo, H. C., Su, K. Y., Liao, H. W., Wang, S. Y., Chepyala, S. R., Chang, L. C. & Kuo, C. H., Jan 1 2019, In : Analytical Chemistry.

Research output: Contribution to journalArticle

Electrospray ionization
Liquid chromatography
Mass spectrometry
Blood
Metabolites
1 Citation (Scopus)

Improved voiding function by deep brain stimulation in traumatic brain-injured animals with bladder dysfunctions

Praveen Rajneesh, C., Lai, C. H., Chen, S. C., Hsieh, T. H., Chin, H. Y. & Peng, C. W., Jan 3 2019, In : International Urology and Nephrology. 51, 1, p. 41-52

Research output: Contribution to journalArticle

Deep Brain Stimulation
Urinary Bladder
Brain
Weights and Measures
Mortality