Find Research Outputs

2019
Open Access
Electronic Health Records
Human Influenza
Incidence
Taiwan
Centers for Disease Control and Prevention (U.S.)

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma

El Dika, I., Lim, H. Y., Yong, W. P., Lin, C. C., Yoon, J. H., Modiano, M., Freilich, B., Choi, H. J., Chao, T. Y., Kelley, R. K., Brown, J., Knox, J., Ryoo, B. Y., Yau, T. & Abou-Alfa, G. K., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
Maximum Tolerated Dose
Hepatocellular Carcinoma
Pharmacokinetics
Safety
Small Interfering RNA
4 Citations (Scopus)

A novel injectable in situ forming gel based on carboxymethyl hexanoyl chitosan/hyaluronic acid polymer blending for sustained release of berberine

Lu, K. Y., Lin, Y. C., Lu, H. T., Ho, Y. C., Weng, S. C., Tsai, M. L. & Mi, F. L., Feb 15 2019, In : Carbohydrate Polymers. 206, p. 664-673 10 p.

Research output: Contribution to journalArticle

Berberine
Hyaluronic acid
Hyaluronic Acid
Chitosan
Polymers

Antagonism of Ca 2+ -sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells

Chen, C. Y., Hour, M. J., Lin, W. C., Wong, K. L., Shiao, L. R., Cheng, K. S., Chan, P. & Leung, Y. M., Jan 1 2019, In : Naunyn-Schmiedeberg's Archives of Pharmacology.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Endothelial Cells
Brain
N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine
Cardiovascular Agents

Antecedent Administration of Glutamine Benefits the Homeostasis of CD4+ T Cells and Attenuates Lung Injury in Mice With Gut-Derived Polymicrobial Sepsis

Lei, C. S., Wu, J. M., Lee, P. C., Kuo, T. C., Chen, P. D., Hou, Y. C., Yeh, S. L. & Lin, M. T., Jan 1 2019, In : Journal of Parenteral and Enteral Nutrition.

Research output: Contribution to journalArticle

Lung Injury
Glutamine
Sepsis
Homeostasis
T-Lymphocytes

Antidepressant use and hepatocellular carcinoma in patients with hepatitis C who had received interferon therapy: A population-based cohort study

Chen, V. C. H., Lu, M. L., Yang, Y. H., Weng, J. C. & Chang, C. C., Jun 15 2019, In : Journal of Affective Disorders. 253, p. 147-153 7 p.

Research output: Contribution to journalArticle

Hepatitis C
Interferons
Antidepressive Agents
Hepatocellular Carcinoma
Cohort Studies

Antifatigue activity and exercise performance of phenolic-rich extracts from calendula officinalis, ribes nigrum, and vaccinium myrtillus

Tung, Y. T., Wu, M. F., Lee, M. C., Wu, J. H., Huang, C. C. & Huang, W. C., Jan 1 2019, In : Nutrients. 11, 8, 1715.

Research output: Contribution to journalArticle

Open Access
Single-Chain Antibodies
Epitopes
Escherichia coli
Amino Acids
OMPA outer membrane proteins
Open Access
2 Citations (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., Jun 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
Acetylation
1 Citation (Scopus)

Antimetastatic effects of Terminalia catappa leaf extracts on cervical cancer through the inhibition of matrix metalloprotein-9 and MAPK pathway

Lee, C. Y., Yang, S. F., Wang, P. H., Su, C. W., Hsu, H. F., Tsai, H. T. & Hsiao, Y. H., Jan 1 2019, In : Environmental Toxicology. 34, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Terminalia
Metalloproteins
Uterine Cervical Neoplasms
cancer
Cells
Open Access
Klebsiella pneumoniae
Taiwan
Pseudomonas aeruginosa
Intensive Care Units
Imipenem

Antimicrobial Gold Nanoclusters: Recent Developments and Future Perspectives

Yougbare, S., Chang, T. K., Tan, S. H., Kuo, J. C., Hsu, P. H., Su, C. Y. & Kuo, T. R., Jun 14 2019, In : International Journal of Molecular Sciences. 20, 12

Research output: Contribution to journalReview article

Open Access
Antimicrobial agents
Nanoclusters
Anti-Infective Agents
nanoclusters
Gold
Cholinergic Antagonists
Parkinson Disease
Dementia
Propensity Score
National Health Programs

Antiseptic effect of conventional povidone-iodine scrub, chlorhexidine scrub, and waterless hand rub in a surgical room: a randomized controlled trial-ADDENDUM

Tsai, J. C., Lin, Y. K., Huang, Y. J., Loh, E. W., Wen, H. Y., Wang, C. H., Tsai, Y. T., Hsieh, W. S. & Tam, K. W., Feb 1 2019, In : Infection Control and Hospital Epidemiology. 40, 2, p. 267-267 1 p.

Research output: Contribution to journalArticle

Povidone-Iodine
Local Anti-Infective Agents
Chlorhexidine
Randomized Controlled Trials
Hand
Povidone-Iodine
Local Anti-Infective Agents
Chlorhexidine
Meta-Analysis
Randomized Controlled Trials

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journalArticle

Antrodia
Catenins
Carcinogenesis
Breast
Down-Regulation

A performance guide for major risk factors control in patients with atherosclerotic cardiovascular disease in Taiwan

Li, Y. H., Chen, J. W., Lin, T. H., Wang, Y. C., Wu, C. C., Yeh, H. I., Huang, C. C., Chang, K. C., Wu, C. K., Chen, P. W., Huang, C. W., Chen, Z. C., Chang, W. T., Huang, W. C., Wang, C. Y., Lee, M. Y., Chao, A. C., Fu, W. R., Tsai, L. K., Tang, S. C. & 5 others, Chan, H. L., Yang, Y. C., Wu, Y. W., Hwang, J. J. & Lin, J-L., Jan 1 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalReview article

Open Access
Taiwan
Cardiovascular Diseases
Cerebrovascular Disorders
Peripheral Arterial Disease
Hypercholesterolemia

A pilot study of motorcycle injury epidemiology in Taiwan

Wu, C. C., Yu, S-H. & Lam, C., 2019, In : International Journal of Community & Family Medicine. 4

Research output: Contribution to journalArticle

Earthquakes
Disasters
Survivors
Wounds and Injuries
Outpatients

Application of the Integrated Behavioral Model to oral self-care behavior of community-dwelling middle-aged and older people in Taiwan

Ho, M-H., Rita Chang, H-C., Lin, Y-K., Traynor, V., Tsai, H-H., Buckwalter, K., Liu, M. F. & Chang, C-C., Jul 26 2019, In : Public Health Nursing.

Research output: Contribution to journalArticle

Independent Living
Self Care
Taiwan
Oral Health
Health Literacy
2 Citations (Scopus)

Applications of cyclic peptide nanotubes (cPNTs)

Hsieh, W. H. & Liaw, J., Jan 2019, (Accepted/In press) In : Journal of Food and Drug Analysis. 27, 1

Research output: Contribution to journalArticle

Peptide Nanotubes
nanotubes
cyclic peptides
Cyclic Peptides
drugs

A preliminary evaluation of psychological stress amongst workers in Taiwan: A cross-sectional survey

Yeh, W. Y., Chiu, W. C., Chen, R. Y., Hu, P. Y. & Tsai, D. M., May 16 2019, In : International Journal of Mental Health Systems. 13, 1, 34.

Research output: Contribution to journalArticle

Open Access
Taiwan
Psychological Stress
Cross-Sectional Studies
Guidelines
Psychiatry

A primary meningioma of the lumbar spine with neck metastasis

Sung, C-W., Hsieh, K. L-C. & Kuo, Y-J., 2019, In : Journal of Spinal Cord Medicine. p. 1-4 4 p.

Research output: Contribution to journalArticle

Meningioma
Spine
Neck
Neoplasm Metastasis
Spinal Cord Neoplasms

A probabilistic model for reducing medication errors: A sensitivity analysis using Electronic Health Records data

Huang, C. Y., Nguyen, P. A., Yang, H. C., Islam, M. M., Liang, C. W., Lee, F. P. & (Jack) Li, Y. C., Mar 1 2019, In : Computer Methods and Programs in Biomedicine. 170, p. 31-38 8 p.

Research output: Contribution to journalArticle

Medication Errors
Electronic Health Records
Statistical Models
Sensitivity analysis
Prescriptions

A rare cause of hematochezia after colonoscopy

Kao, W. Y., Cheng, T. & Chang, C. C., 2019, In : Digestive and Liver Disease.

Research output: Contribution to journalArticle

Gastrointestinal Hemorrhage
Colonoscopy

Arecoline-regulated ataxia telangiectasia mutated expression level in oral cancer progression

Tu, H. F., Chen, M. Y., Lai, J. C. Y., Chen, Y. L., Wong, Y. W., Yang, C. C., Chen, H. Y., Hsia, S. M., Shih, Y. H. & Shieh, T. M., Jan 1 2019, In : Head and Neck.

Research output: Contribution to journalArticle

Arecoline
Ataxia Telangiectasia
Mouth Neoplasms
Squamous Cell Carcinoma
DNA Repair
1 Citation (Scopus)

Are Neonatal Trials Better Conducted and Reported over the Last 6 Decades? An Analysis on Their Risk-of-Bias Status in Cochrane Reviews

Lai, N. M., Ong, J. M. J., Chen, K. H., Chaiyakunapruk, N., Ovelman, C. & Soll, R., 2019, In : Neonatology. p. 1-9 9 p.

Research output: Contribution to journalReview article

Neonatology
Research Design
Research

Argon plasma surface modified porcine bone substitute improved osteoblast-like cell behavior

Choy, C. S., Salamanca, E., Lin, P. Y., Huang, H. M., Teng, N. C., Pan, Y. H. & Chang, W. J., Jan 1 2019, In : Coatings. 9, 2, p. 9-134 126 p.

Research output: Contribution to journalArticle

Open Access
Bone Substitutes
osteoblasts
Argon
Osteoblasts
argon plasma

Artificial Intelligence and Visual Analytics: A Deep-Learning Approach to Analyze Hotel Reviews & Responses

Ku, C-H., Chang, Y-C., Wang, Y., Chen, C-H. & Hsiao, S-H., Jan 8 2019, 52nd Hawaii International Conference on System Sciences .

Research output: Chapter in Book/Report/Conference proceedingConference contribution

research method
university teacher
history
interview
Research Methods
1 Citation (Scopus)

ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W. Y., Li, C. R., Lin, C. Y., Hwang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In : Oncogene. 38, 8, p. 1340-1353

Research output: Contribution to journalArticle

Catenins
Microcephaly
Prostatic Neoplasms
Neoplastic Stem Cells
Neoplasms
Open Access
Acid Sensing Ion Channels
Brain Concussion
Dizziness
Alleles
Genes
Open Access
Dementia
Aptitude
Appointments and Schedules
Internship and Residency
Activities of Daily Living

Association between Anticholinergic Medication Use and Risk of Dementia among Patients with Parkinson's Disease

Sheu, J. J., Tsai, M. T., Erickson, S. R. & Wu, C. H., Jan 1 2019, In : Pharmacotherapy. 39, 8, p. 798-808 11 p.

Research output: Contribution to journalArticle

Association between gout and cardiovascular disease risk: A nation-wide case-control study

Liang, C-W., Islam, M. M., Poly, T. N., Yang, H-C. & Jack Li, Y-C., May 2019, In : Joint Bone Spine.

Research output: Contribution to journalArticle

Association between heat stroke and ischemic heart disease: A national longitudinal cohort study in Taiwan

Tseng, M. F., Chou, C. L., Chung, C. H., Chien, W. C., Chen, Y. K., Yang, H. C. & Chu, P., Jan 1 2019, In : European Journal of Internal Medicine. 59, p. 97-103 7 p.

Research output: Contribution to journalArticle

Heat Stroke
Taiwan
Myocardial Ischemia
Longitudinal Studies
Cohort Studies
Open Access
Vertebral Artery
Infarction
Stroke
Control Groups
Intracranial Arteriosclerosis

Association between Parkinson's disease and atrial fibrillation: A population-based study

Hong, C. T., Chan, L., Wu, D., Chen, W. T. & Chien, L. N., Jan 1 2019, In : Frontiers in Neurology. 10, FEB, 22.

Research output: Contribution to journalArticle

Open Access
Atrial Fibrillation
Parkinson Disease
Population
Autonomic Nervous System
Case-Control Studies

Association Between Psoriasis and Dementia: A Population-Based Case-Control Study

Lin, C-C., Lin, H-C. & Chiu, H-W., Jun 1 2019, In : American Journal of Clinical Dermatology. 20, 3, p. 457-463 7 p.

Research output: Contribution to journalArticle

Psoriasis
Dementia
Case-Control Studies
Population
Bullous Pemphigoid

Association between sedative-hypnotics and subsequent cancer in patients with and without insomnia: A 14-year follow-up study in Taiwan

Fang, H. F., Lee, T. Y., Hui, K. C., Ho Yim, H. C., Chi, M. J. & Chung, M. H., May 21 2019, In : Journal of Cancer. 10, 10, p. 2288-2298 11 p.

Research output: Contribution to journalArticle

Open Access
Sleep Initiation and Maintenance Disorders
Hypnotics and Sedatives
Taiwan
Neoplasms
Mouth Neoplasms

Association of chronic hepatitis B virus infection with age-related macular degeneration

Wu, C. M., Su, F. H., Wang, W. C., Lin, C. P., Kamiza, A. B., Chang, S. N. & Yeh, C. C., Jan 1 2019, In : Acta Ophthalmologica.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Macular Degeneration
Virus Diseases
Hepatitis B virus
Cercopithecine Herpesvirus 1

Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

Kao, C. C., Cheng, S. Y., Wang, Y. J., Chien, S. C., Hsu, Y. W., Wu, M. Y., Lu, H. F., Nam, S., Sun, T., Wu, M. S. & Chang, W. C., Jun 5 2019, In : BMC Nephrology. 20, 1, 203.

Research output: Contribution to journalArticle

Open Access
Endothelins
Chronic Kidney Failure
Bacteremia
Infection
Single Nucleotide Polymorphism
Open Access
Chronic Renal Insufficiency
Cross-Sectional Studies
Kidney
Weights and Measures
Population

Association of Metformin Use With End-Stage Renal Disease in Patients With Type 2 Diabetes Mellitus: A Nationwide Cohort Study Under the Pay-for-Performance Program

Lee, M. C., Lee, C. H., Chang, L. Y., Chang, C. H., Zhang, J. F., Lee, M. R., Wang, J. Y. & Chen, S. M., Jan 1 2019, In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Incentive Reimbursement
Metformin
Type 2 Diabetes Mellitus
Chronic Kidney Failure
Cohort Studies

Associations between sleep disturbances and suicidal ideation, plans, and attempts in adolescents: a systematic review and meta-analysis

Liu, J. W., Tu, Y. K., Lai, Y. F., Lee, H. C., Tsai, P. S., Chen, T. J., Huang, H. C., Chen, Y. T. & Chiu, H. Y., Jun 11 2019, In : Sleep. 42, 6

Research output: Contribution to journalArticle

Open Access
Suicidal Ideation
Meta-Analysis
Sleep
Suicide
Cross-Sectional Studies
1 Citation (Scopus)
Hashimoto Disease
Osteopontin
Lymphocytes
Graves Disease
Thyroid Diseases
Renal Dialysis
Meta-Analysis
Catheters
Confidence Intervals
Incidence