Find Research Outputs

2018

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cardiac Myocytes
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Enzymes
2 Citations

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Fibroblasts
Nicotine
Chemical activation
Cells
Oxidative stress
MAP Kinase Signaling System
Nicotinic Receptors
Spasm
p38 Mitogen-Activated Protein Kinases

Active Tumor-Targeted co-Delivery of Epigallocatechin Gallate and Doxorubicin in Nanoparticles for Combination Gastric Cancer Therapy

Mi, F. L., Wang, L. F., Chu, P. Y., Peng, S. L., Feng, C. L., Lai, Y. J., Li, J. N. & Lin, Y. H., Aug 13 2018, In : ACS Biomaterials Science and Engineering. 4, 8, p. 2847-2859 13 p.

Research output: Contribution to journalArticle

Doxorubicin
Tumors
Cells
Nanoparticles
Hyaluronic acid

Acute aortoiliac thrombosis due to minimal change disease

Tam, W. C., Lin, C. H., Chuang, C. Y. & Cheng, C. Y., Apr 1 2018, In : Nephrology. 23, 4, p. 377-378 2 p.

Research output: Contribution to journalLetter

Lipoid Nephrosis
Thrombosis

Acute biliary events during anti-tuberculosis treatment: Hospital case series and a nationwide cohort study

Chang, L. Y., Lee, C. H., Chang, C. H., Lee, M. C., Lee, M. R., Wang, J. Y. & Lee, L. N., Feb 1 2018, In : BMC Infectious Diseases. 18, 1, 64.

Research output: Contribution to journalArticle

Chronic Disease Hospitals
Tuberculosis
Cohort Studies
Pulmonary Tuberculosis
Therapeutics
1 Citations

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

Chen, Y. P., Kuo, W. W., Baskaran, R., Day, C. H., Chen, R. J., Wen, S. Y., Ho, T. J., Padma, V. V., Kuo, C. H. & Huang, C. Y., Apr 1 2018, In : Journal of Cellular Biochemistry. 119, 4, p. 3363-3372 10 p.

Research output: Contribution to journalArticle

Glucose Transporter Type 4
Palmitic Acid
Cardiac Myocytes
Fatty Acids
Apoptosis

ADAM17/EGFR-dependent ERK activation mediates thrombin-induced CTGF expression in human lung fibroblasts

Chen, H. Y., Lin, C. H. & Chen, B. C., Sep 1 2018, In : Experimental Cell Research. 370, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

Connective Tissue Growth Factor
Disintegrins
Extracellular Signal-Regulated MAP Kinases
Metalloproteases
Epidermal Growth Factor Receptor
1 Citations

Addressing stem cell therapeutic approaches in pathobiology of diabetes and its complications

Peng, B. Y., Dubey, N. K., Mishra, V. K., Tsai, F. C., Dubey, R., Deng, W. P. & Wei, H. J., Jan 1 2018, In : Journal of Diabetes Research. 2018, 7806435.

Research output: Contribution to journalArticle

Diabetes Complications
Diabetes Mellitus
Stem Cells
Multipotent Stem Cells
Pluripotent Stem Cells

A Descriptive, Retrospective Study of Using an Oblique Downward-design Gluteus Maximus Myocutaneous Flap for Reconstruction of Ischial Pressure Ulcers

Chou, C. Y., Sun, Y. S., Shih, Y. J., Tzeng, Y. S., Chang, S. C., Dai, N. T. & Lin, C. T., Mar 1 2018, In : Ostomy/wound management. 64, 3, p. 40-44 5 p.

Research output: Contribution to journalArticle

Myocutaneous Flap
Pressure Ulcer
Retrospective Studies
Wound Healing
Ulcer

A developed NK-92MI cell line with siglec-7neg phenotype exhibits high and sustainable cytotoxicity against leukemia cells

Huang, C. H., Liao, Y. J., Fan, T. H., Chiou, T. J., Lin, Y. H. & Twu, Y. C., Apr 4 2018, In : International Journal of Molecular Sciences. 19, 4, 1073.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
phenotype
leukemias
Cytotoxicity
cultured cells
Dipeptidyl-Peptidase IV Inhibitors
Keratinocytes
Wound Healing
Adiponectin
Medical problems

Adiponectin gene polymorphisms and obesity increase the susceptibility to arsenic-related renal cell carcinoma

Hsueh, Y. M., Chen, W. J., Lin, Y. C., Huang, C. Y., Shiue, H. S., Yang, S. M., Ao, P. L., Pu, Y. S. & Su, C. T., Jul 1 2018, In : Toxicology and Applied Pharmacology. 350, p. 11-20 10 p.

Research output: Contribution to journalArticle

Adiponectin
Arsenic
Polymorphism
Renal Cell Carcinoma
Obesity
3 Citations
Adjuvant Radiotherapy
Adjuvant Chemoradiotherapy
Adjuvant Chemotherapy
Adenocarcinoma
Chemoradiotherapy

Adolescent tobacco coupon receipt, vulnerability characteristics and subsequent tobacco use: Analysis of PATH Study, Waves 1 and 2

Rose, S. W., Glasser, A. M., Zhou, Y., Cruz, T. B., Cohn, A. M., Lienemann, B. A., Byron, M. J., Huang, L. L., Meissner, H. I., Baezconde-Garbanati, L. & Unger, J. B., Feb 22 2018, (Accepted/In press) In : Tobacco control.

Research output: Contribution to journalArticle

Tobacco Use
nicotine
Tobacco
vulnerability
adolescent

Adolescent tobacco coupon receipt, vulnerability characteristics and subsequent tobacco use: analysis of PATH Study, Waves 1 and 2

Rose, S. W., Glasser, A. M., Zhou, Y., Cruz, T. B., Cohn, A. M., Lienemann, B. A., Byron, M. J., Huang, L-L., Meissner, H. I., Baezconde-Garbanati, L. & Unger, J. B., Feb 22 2018, In : Tobacco Control.

Research output: Contribution to journalArticle

Tobacco Use
nicotine
Tobacco
vulnerability
adolescent

Adverse outcomes of long-term use of proton pump inhibitors: a systematic review and meta-analysis

Islam, M. M., Poly, T. N., Walther, B. A., Dubey, N. K., Anggraini Ningrum, D. N., Shabbir, S-A. & Jack Li, Y-C., Jul 19 2018, In : European Journal of Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
Meta-Analysis
Odds Ratio
Confidence Intervals
Hip Fractures

A facile measurement for monitoring dragline silk dope concentration in Nephila pilipes upon spinning

Wu, H. C., Wu, S. R., Yang, T. C. K. & Yang, J. C., Oct 12 2018, In : Materials. 11, 10, 1951.

Research output: Contribution to journalArticle

Silk
Monitoring
Liquids
Fibers
Tensile strength

A Functional Near-Infrared Spectroscopy Study of State Anxiety and Auditory Working Memory Load

Tseng, Y. L., Lu, C. F., Wu, S. M., Shimada, S., Huang, T. & Lu, G. Y., Aug 7 2018, In : Frontiers in Human Neuroscience. 12, 313.

Research output: Contribution to journalArticle

Near-Infrared Spectroscopy
Prefrontal Cortex
Short-Term Memory
Anxiety
Acoustic Stimulation

Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage

Jian, Q. L., HuangFu, W. C., Lee, Y. H. & Liu, I. H., Jan 1 2018, In : PeerJ. 2018, 10, e5739.

Research output: Contribution to journalArticle

chondrocytes
Cartilage
Zebrafish
Chondrocytes
Danio rerio
1 Citations

A gelatin hydrogel-containing nano-organic PEI–Ppy with a photothermal responsive effect for tissue engineering applications

Satapathy, M. K., Nyambat, B., Chiang, C. W., Chen, C. H., Wong, P. C., Ho, P. H., Jheng, P. R., Burnouf, T., Tseng, C. L. & Chuang, E. Y., Jan 1 2018, In : Molecules. 23, 6, 1256.

Research output: Contribution to journalArticle

Polyethyleneimine
tissue engineering
Hydrogel
gelatins
polypyrroles
4 Citations

Aging modulates the substrate and triggers remodeling in atrial fibrillation

Lin, Y. K., Chen, Y. A., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : Circulation Journal. 82, 5, p. 1237-1244 8 p.

Research output: Contribution to journalReview article

Atrial Fibrillation
Atrial Remodeling
Muscular Diseases
Comorbidity
Veins

A hackathon promoting Taiwanese health-IoT innovation

Iqbal, U., Dagan, A., Syed-Abdul, S., Celi, L. A., Hsu, M-H. & Li, Y-CJ., 2018, In : Computer Methods and Programs in Biomedicine. 163, p. 29-32 4 p.

Research output: Contribution to journalArticle

1 Citations

A high sensitivity bead-based immunoassay with nanofluidic preconcentration for biomarker detection

Fan, Y. J., Deng, C. Z., Chung, P. S., Tian, W. C. & Sheen, H. J., Nov 1 2018, In : Sensors and Actuators, B: Chemical. 272, p. 502-509 8 p.

Research output: Contribution to journalArticle

Nanofluidics
immunoassay
biomarkers
Biomarkers
antigens

A hybrid session key exchange algorithm for highly-sensitive IP-based institutional communications

Zhuang, Z. Y., Hsu, Y. C., Nurmi, K., Chen, Y. C., Liu, H. H. & Tseng, T. S., Jan 1 2018, In : Microsystem Technologies. 24, 1, p. 273-283 11 p.

Research output: Contribution to journalArticle

communication
Communication
Electronic document identification systems
exchanging
Security of data

AI in Medicine: Big Data Remains a Challenge

Lin, M. C., Iqbal, U. & Li, Y. C., Oct 1 2018, In : Computer Methods and Programs in Biomedicine. 164, p. A1

Research output: Contribution to journalEditorial

Medicine
Big data
1 Citations

A Large Urinary Bladder Hemangioma Mimicking Urachal Cancer: A Case Report and Literature Review

Syu, S. H., Chan, K. S., Hsiao, C. H., Chen, W. Y., Lee, L. M. & Wen, Y. C., Jan 1 2018, (Accepted/In press) In : Urology.

Research output: Contribution to journalArticle

Hemangioma
Urinary Bladder
Hematuria
Urachus
Cavernous Hemangioma
Laminaria
Seaweed
Sodium-Hydrogen Antiporter
Chronic Renal Insufficiency
Protein Isoforms
3 Citations

A low microRNA-630 expression confers resistance to tyrosine kinase inhibitors in EGFR-mutated lung adenocarcinomas via miR-630/YAP1/ERK feedback loop

Wu, D. W., Wang, Y. C., Wang, L., Chen, C. Y. & Lee, H., Jan 1 2018, In : Theranostics. 8, 5, p. 1256-1269 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Protein-Tyrosine Kinases
bcl-Associated Death Protein
Neoplasms
Adenocarcinoma of lung

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Oct 23 2018, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

Cell Polarity
beta Catenin
Stem cells
Mesenchymal Stromal Cells
Shear stress
1 Citations

Altered pattern of monocyte differentiation and monocyte-derived TGF-β1 in severe asthma

Hung, C. H., Wang, C. C., Suen, J. L., Sheu, C. C., Kuo, C. H., Liao, W. T., Yang, Y. H., Wu, C. C., Leung, S. Y., Lai, R. S., Lin, C. C., Wei, Y. F., Lee, C. Y., Huang, M. S. & Huang, S. K., Dec 1 2018, In : Scientific Reports. 8, 1, 919.

Research output: Contribution to journalArticle

Monocytes
Asthma
Macrophages
Lung
Airway Remodeling

Altered predictive capability of the brain network EEG model in schizophrenia during cognition

Gomez-Pilar, J., Poza, J., Gómez, C., Northoff, G., Lubeiro, A., Cea-Cañas, B. B., Molina, V. & Hornero, R., Jan 1 2018, (Accepted/In press) In : Schizophrenia Research.

Research output: Contribution to journalArticle

Cognition
Electroencephalography
Schizophrenia
Brain
Healthy Volunteers
1 Citations

Alzheimer's disease is associated with prostate cancer: A population-based study

Lin, H. C., Kao, L. T., Chung, S. D., Huang, C. C., Shia, B. C. & Huang, C. Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7616-7622 7 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Alzheimer Disease
Population
Odds Ratio
Confidence Intervals

A machine learning texture model for classifying lung cancer subtypes using preliminary bronchoscopic findings

Feng, P. H., Lin, Y. T. & Lo, C. M., Jan 1 2018, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Lung Neoplasms
Color
Bronchoscopy
ROC Curve
Squamous Cell Carcinoma
2 Citations

Amentoflavone enhances the therapeutic efficacy of sorafenib by inhibiting anti-apoptotic potential and potentiating apoptosis in hepatocellular carcinoma in vivo

Tsai, J. J., Hsu, F. T., Pan, P. J., Chen, C. W. & Kuo, Y. C., Apr 1 2018, In : Anticancer Research. 38, 4, p. 2119-2125 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Apoptosis
Therapeutics
Neoplasms
Apoptosis Regulatory Proteins

Amentoflavone Induces Apoptosis and Inhibits NF-ĸB-modulated Anti-apoptotic Signaling in Glioblastoma Cells

Yen, T-H., Hsieh, C-L., Liu, T-T., Huang, C-S., Chen, Y-C., Chuang, Y-C., Lin, S-S. & Hsu, F-T., Feb 25 2018, In : In Vivo. 32, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Glioblastoma
Apoptosis
Myeloid Leukemia
Myeloid Cells
Fas-Associated Death Domain Protein
1 Citations

Amentoflavone Inhibits ERK-modulated Tumor Progression in Hepatocellular Carcinoma In Vitro

Lee, K-C., Tsai, J. J., Kuo, Y. C., Chuang, Y-C., Lin, S. S. & Hsu, F-T., May 2018, In : In Vivo. 32, 3, p. 549-554

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Tumors
Hepatocellular Carcinoma
Neoplasms
Assays

Amentoflavone inhibits hepatocellular carcinoma progression through blockage of ERK/NF-κB activation

Lee, K. C., Chen, W. T., Liu, Y. C., Lin, S. S. & Hsu, F. T., Sep 1 2018, In : In Vivo. 32, 5, p. 1097-1103 7 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Hepatocellular Carcinoma
Neoplasms
Body Weight
Liver

A method for respiration rate detection in wrist PPG signal using Holo-Hilbert spectrum

Chang, H. H., Hsu, C. C., Chen, C. Y., Lee, W. K., Hsu, H. T., Shyu, K. K., Yeh, J. R., Lin, P. J. & Lee, P. L., Sep 15 2018, In : IEEE Sensors Journal. 18, 18, p. 7560-7569 10 p., 8410910.

Research output: Contribution to journalArticle

wrist
respiration
Spectrum analysis
spectrum analysis
Plethysmography

A Mobile Cloud-Based Biofeedback Platform for Evaluating Medication Response: 7th IEEE International Symposium on Cloud and Service Computing, SC2 2017

Lai, Y-Z., Tai, C-H., Chang, Y-S. & Chung, K-H., 2018, p. 183-188. 6 p.

Research output: Contribution to conferencePaper

Biofeedback
Medicine
Brain
Fusion reactions
Communication
Reducing Diet
Fish Oils
fish oils
interleukin-6
Weight Loss
1 Citations
Military Personnel
Ankle
Ankle Lateral Ligament
Orthopedics
Foot

Analgesic Effects of Locally Administered Ketorolac-based Analgesics after Breast Surgery A Meta-Analysis of Randomized Controlled Trials

Chen, J. Y., Feng, I. J., Loh, E. W., Wang, L. K., Lin, C. C. & Tam, K. W., Jan 1 2018, In : Clinical Journal of Pain. 34, 6, p. 577-584 8 p.

Research output: Contribution to journalArticle

Ketorolac
Analgesics
Meta-Analysis
Breast
Randomized Controlled Trials
Dementia
Cohort Studies
Wounds and Injuries
Asphyxia
Poisoning

Analysis of Titin in Red and White Muscles: Crucial Role on Muscle Contractions Using a Fish Model

Wu, M. P., Chang, N-C., Chung, C-L., Chiu, W-C., Hsu, C-C., Chen, H. M., Sheu, J-R., Jayakumar, T., Chou, D-S. & Fong, T-H., Nov 18 2018, In : BioMed Research International. 11 p., 5816875.

Research output: Contribution to journalArticle

An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets

Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., Nov 14 2018, In : Journal of Clinical Medicine. 7, 11

Research output: Contribution to journalArticle

Phospholipase D
Blood Platelets
Platelet Activation
Platelet Aggregation
Thrombosis

An automated technique to construct a knowledge base of traditional Chinese herbal medicine for cancers: An exploratory study for breast cancer

Nguyen, P. A., Yang, H. C., Xu, R. & Li, Y. C., Jan 1 2018, Building Continents of Knowledge in Oceans of Data: The Future of Co-Created eHealth - Proceedings of MIE 2018. IOS Press, p. 661-665 5 p. (Studies in Health Technology and Informatics; vol. 247).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Knowledge Bases
Herbal Medicine
Association rules
Gold
Health insurance
1 Citations
Activating Transcription Factors
Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms
Transcription Factors
Defecation
Mucus

An epidemiological human disease network derived from disease Co-occurrence in Taiwan

Jiang, Y., Ma, S., Shia, B. C. & Lee, T. S., Dec 1 2018, In : Scientific Reports. 8, 1, 4557.

Research output: Contribution to journalArticle

Health insurance
Health care