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• 2021

  Perturbation of Ca²⁺ stores and store-operated Ca²⁺ influx by lidocaine in neuronal N2A and NG108-15 cells

  Wu, K. C., Wong, K. L., Shiao, L. R., Chen, C. Y., Chan, P. & Leung, Y. M., Aug 5 2021, In: European Journal of Pharmacology. 904, 174115.

  Research output: Contribution to journal › Article › peer-review

• Pharmacoinformatics and preclinical studies of nsc765690 and nsc765599, potential stat3/cdk2/4/6 inhibitors with antitumor activities against nci60 human tumor cell lines

  Lawal, B., Liu, Y. L., Mokgautsi, N., Khedkar, H., Sumitra, M. R., Wu, A. T. H. & Huang, H. S., 2021, In: Biomedicines. 9, 1, p. 1-22 22 p., 92.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Citations (Scopus)

• Pharmacokinetics and Pharmacodynamics of Novel Long-Acting Ropeginterferon Alfa-2b in Healthy Chinese Subjects

  Huang, Y. W., Tsai, C. Y., Tsai, C. W., Wang, W., Zhang, J., Qin, A., Teng, C., Song, B. & Wang, M. X., Sep 2021, In: Advances in Therapy. 38, 9, p. 4756-4770 15 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Pharmacologically inhibiting glycogen synthase kinase-3β ameliorates renal inflammation and nephrotoxicity in an animal model of cisplatin-induced acute kidney injury

  Hsing, C. H., Tsai, C. C., Chen, C. L., Lin, Y. H., Tseng, P. C., Satria, R. D. & Lin, C. F., Aug 2021, In: Biomedicines. 9, 8, 887.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Phase-Approaching Stimulation Sequence for SSVEP-Based BCI: A Practical Use in VR/AR HMD

  Hsu, H. T., Shyu, K. K., Hsu, C. C., Lee, L. H. & Lee, P. L., 2021, In: IEEE Transactions on Neural Systems and Rehabilitation Engineering. 29, p. 2754-2764 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Phase-Dependent MoS₂Nanoflowers for Light-Driven Antibacterial Application

  Mutalik, C., Krisnawati, D. I., Patil, S. B., Khafid, M., Atmojo, D. S., Santoso, P., Lu, S. C., Wang, D. Y. & Kuo, T. R., Jun 14 2021, In: ACS Sustainable Chemistry and Engineering. 9, 23, p. 7904-7912 9 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Phase I Dose-Escalation Study of SCB01A, a Microtubule Inhibitor with Vascular Disrupting Activity, in Patients with Advanced Solid Tumors

  Shiah, H. S., Chiang, N. J., Lin, C. C., Yen, C. J., Tsai, H. J., Wu, S. Y., Su, W. C., Chang, K. Y., Wang, C. C., Chang, J. Y. & Chen, L. T., Apr 2021, In: Oncologist. 26, 4, p. e567-e579

  Research output: Contribution to journal › Article › peer-review

  Open Access

• PH-Dependent mechanisms and kinetics of the removal of acetaminophen by manganese dioxide

  Hu, C. Y., Kuan, W. H., Lee, I. J. & Liu, Y. J., Apr 2021, In: Journal of Environmental Chemical Engineering. 9, 2, 105129.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan

  Hsu, Y. C., Yu, C. H., Chen, Y. M., Roberts, K. G., Ni, Y. L., Lin, K. H., Jou, S. T., Lu, M. Y., Chen, S. H., Wu, K. H., Chang, H. H., Lin, D. T., Lin, S. W., Lin, Z. S., Chiu, W. T., Chang, C. C., Ho, B. C., Mullighan, C. G., Yu, S. L. & Yang, Y. L., Dec 2021, In: Scientific Reports. 11, 1, 5802.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance

  Wang, L. T., Liu, K. Y., Chiou, S. S., Huang, S. K., Hsu, S. H. & Wang, S. N., Nov 1 2021, In: Cancer Letters. 520, p. 160-171 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Photoreactive Cytosine-Functionalized Self-Assembled Micelles with Enhanced Cellular Uptake Capability for Efficient Cancer Chemotherapy

  Manayia, A. H., Ilhami, F. B., Lee, A. W. & Cheng, C. C., Dec 13 2021, In: Biomacromolecules. 22, 12, p. 5307-5318 12 p.

  Research output: Contribution to journal › Article › peer-review

• Photothermal-Irradiated Polyethyleneimine-Polypyrrole Nanopigment Film-Coated Polyethylene Fabrics for Infrared-Inspired with Pathogenic Evaluation

  Hsiao, Y. C., Jheng, P. R., Nguyen, H. T., Chen, Y. H., Manga, Y. B., Lu, L. S., Rethi, L., Chen, C. H., Huang, T. W., Lin, J. D., Chang, T. K., Ho, Y. C. & Chuang, E. Y., Jan 20 2021, In: ACS Applied Materials and Interfaces. 13, 2, p. 2483-2495 13 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Phthalate exposure pattern in breast milk within a six-month postpartum time in southern taiwan

  Hung, S. C., Lin, T. I., Suen, J. L., Liu, H. K., Wu, P. L., Wu, C. Y., Yang, Y. C. S. H., Yang, S. N. & Yang, Y. N., Jun 1 2021, In: International journal of environmental research and public health. 18, 11, 5726.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Physical Activity and Diet Quality Modify the Association between Comorbidity and Disability among Stroke Patients

  Nguyen, L. T. K., Do, B. N., Vu, D. N., Pham, K. M., Vu, M-T., Nguyen, H. C., Tran, T. V., Le, H. P., Nguyen, T. T. P., Nguyen, Q. M., Tran, C. Q., Nguyen, K. T., Yang, S-H., Chao, J. C-J. & Van Duong, T., 2021, In: Nutrients. 13, 5

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Physical Activity and the Risk of Hemorrhagic Stroke: A Population-Based Longitudinal Follow-Up Study in Taiwan

  Feng, S. H., Chen, L. S., Yeh, K. C. & Pan, S. L., Dec 23 2021, In: Frontiers in Medicine. 8, 791772.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Physical ergonomics in peripheral nerve block

  Fathil, S. M., Ghani, M. R. A., Chen, K. Y., Lee, P., Hou, J. D. & Lin, J. A., Oct 1 2021, In: Applied Sciences (Switzerland). 11, 20, 9736.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

• Physiological testosterone attenuates profibrotic activities of rat cardiac fibroblasts through modulation of nitric oxide and calcium homeostasis

  Chung, C-C., Lin, Y-K., Kao, Y-H., Lin, S-H. & Chen, Y-J., 2021, In: Endocrine Journal.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Phytochemistry, pharmacology, and nutraceutical profile of carissa species: An updated review

  Dhatwalia, J., Kumari, A., Verma, R., Upadhyay, N., Guleria, I., Lal, S., Thakur, S., Gudeta, K., Kumar, V., Chao, J. C. J., Sharma, S., Kumar, A., Manicum, A. L. E., Lorenzo, J. M. & Amarowicz, R., Nov 2021, In: Molecules. 26, 22, 7010.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  2 Citations (Scopus)

• Phytogalactolipid dlgg inhibits mouse melanoma brain metastasis through regulating oxylipin activity and re-programming macrophage polarity in the tumor microenvironment

  Yang, C. C., Chang, M. T., Chang, C. K. & Shyur, L. F., Aug 2 2021, In: Cancers. 13, 16, 4120.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• PINK1-mediated inhibition of EGFR dimerization and activation impedes EGFR-driven lung tumorigenesis

  Emily Pei-Ying Lin, P-Y. L., Huang, B. T., Lai, W. Y., Tseng, Y. T., Yang, S. C., Kuo, H. C. & Yang, P. C., Apr 2021, In: Cancer Research. 81, 7, p. 1745-1757 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression

  Mandal, J. P., Shiue, C. N., Chen, Y. C., Lee, M. C., Yang, H. H., Chang, H. H., Hu, C. T., Liao, P. C., Hui, L. C., You, R. I. & Wu, W. S., Feb 1 2021, In: Free Radical Biology and Medicine. 163, p. 69-87 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)

• Plasma 25(Oh)d concentrations and gestational diabetes mellitus among pregnant women in taiwan

  Pham, T. T. M., Huang, Y. L., Chao, J. C. J., Chang, J. S., Chen, Y. C., Wang, F. F. & Bai, C. H., Aug 2021, In: Nutrients. 13, 8, 2538.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Plasma d-glutamate levels for detecting mild cognitive impairment and Alzheimer’s disease: Machine learning approaches

  Chang, C. H., Lin, C. H., Liu, C. Y., Huang, C. S., Chen, S. J., Lin, W. C., Yang, H. T. & Lane, H. Y., Mar 2021, In: Journal of Psychopharmacology. 35, 3, p. 265-272 8 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Plasma extracellular vesicles tau and β-amyloid as biomarkers of cognitive dysfunction of Parkinson's disease

  Chung, C. C., Chan, L., Chen, J. H., Bamodu, O. A., Chiu, H. W. & Hong, C. T., Oct 2021, In: FASEB Journal. 35, 10, e21895.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Plasma extracellular vesicle α-synuclein level in patients with parkinson’s disease

  Chung, C. C., Chan, L., Chen, J. H., Hung, Y. C. & Hong, C. T., May 2021, In: Biomolecules. 11, 5, 744.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Plasma vitamin B₁₂ and folate alter the association of blood lead and cadmium and total urinary arsenic levels with chronic kidney disease in a Taiwanese population

  Hsueh, Y. M., Huang, Y. L., Lin, Y. F., Shiue, H. S., Lin, Y. C. & Chen, H. H., Nov 2021, In: Nutrients. 13, 11, 3841.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Plasmonic gold nanoisland film for bacterial theranostics

  Tan, S. H., Yougbaré, S., Tao, H. Y., Chang, C. C. & Kuo, T. R., Nov 2021, In: Nanomaterials. 11, 11, 3139.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism

  Lee, T. Y., Lu, W. J., Changou, C. A., Hsiung, Y. C., Trang, N. T. T., Lee, C. Y., Chang, T. H., Jayakumar, T., Hsieh, C. Y., Yang, C. H., Chang, C. C., Chen, R. J., Sheu, J. R. & Lin, K. H., Apr 2021, In: Autophagy. 17, 12, p. 1-18 18 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Platelet‐derived biomaterials exert chondroprotective and chondroregenerative effects on diabetes mellitus‐induced intervertebral disc degeneration

  Lo, W. C., Chang, C. C., Chan, C. H., Singh, A. K., Deng, Y. H., Lin, C. Y., Tsao, W., Chien, S. T., Lin, C. H. & Deng, W. P., Oct 2021, In: Life. 11, 10, 1054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Platelet-Derived Biomaterials Inhibit Nicotine-Induced Intervertebral Disc Degeneration Through Regulating IGF-1/AKT/IRS-1 Signaling Axis

  Lo, W. C., Chiou, C. S., Tsai, F. C., Chan, C. H., Mao, S., Deng, Y. H., Wu, C. Y., Peng, B. Y. & Deng, W. P., 2021, In: Cell Transplantation. 30

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Platelet-derived biomaterials-mediated improvement of bone injury through migratory ability of embryonic fibroblasts: In vitro and in vivo evidence

  Chou, Y. R., Lo, W. C., Dubey, N. K., Lu, J. H., Liu, H. Y., Tsai, C. Y., Deng, Y. H., Wu, C. M., Huang, M. S. & Deng, W. P., Feb 15 2021, In: Aging. 13, 3, p. 3605-3617 13 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Platelet-derived growth factor receptor-α subunit targeting suppresses metastasis in advanced thyroid cancer in vitro and in vivo

  Lin, C. L., Tsai, M. L., Chen, Y. H., Liu, W. N., Lin, C. Y., Hsu, K. W., Huang, C. Y., Chang, Y. J., Wei, P. L., Chen, S. H., Huang, L. C. & Lee, C. H., Sep 2021, In: Biomolecules and Therapeutics. 29, 5, p. 551-561 11 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Platonin, a cyanine photosensitizing dye, ameliorates inflammatory responses in vascular smooth muscle cells by modulating inflammatory transcription factors

  Chiu, C. W., Yang, C. H., Tsai, J. H., Hsieh, C. Y. & Huang, S. Y., Feb 1 2021, In: Applied Sciences (Switzerland). 11, 3, p. 1-13 13 p., 1130.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation

  Liu, J. F., Chi, M. C., Lin, C. Y., Lee, C. W., Chang, T. M., Han, C. K., Huang, Y. L., Fong, Y. C., Chen, H. T. & Tang, C. H., Mar 2021, In: Journal of Cellular Physiology. 236, 3, p. 2205-2213 9 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Pneumocystis jirovecii pneumonia in autoimmune rheumatic diseases: a nationwide population-based study

  Hsu, H. C., Chang, Y. S., Hou, T. Y., Chen, L. F., Hu, L. F., Lin, T. M., Chiou, C. S., Tsai, K. L., Lin, S. H., Kuo, P. I., Chen, W. S., Lin, Y. C., Chen, J. H. & Chang, C. C., 2021, (Accepted/In press) In: Clinical Rheumatology. 40, 9, p. 3755-3763 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Point-of-Care Ultrasound for Posterior Shoulder Dislocation: A Better Standard than X-Ray?

  Huang, W. C., Chu, K. C. W. & Hsu, Y. P., Mar 1 2021, In: Southern Medical Journal. 114, 3, p. 192 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Citation (Scopus)

• Polarization of type 1 macrophages is associated with the severity of viral encephalitis caused by japanese encephalitis virus and dengue virus

  Jhan, M. K., Chen, C. L., Shen, T. J., Tseng, P. C., Wang, Y. T., Satria, R. D., Yu, C. Y. & Lin, C. F., Nov 2021, In: Cells. 10, 11, 3181.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Pollen-Mimetic Metal-Organic Frameworks with Tunable Spike-Like Nanostructures That Promote Cell Interactions to Improve Antigen-Specific Humoral Immunity

  Chen, P. M., Pan, W. Y., Luo, P. K., Phung, H. N., Liu, Y. M., Chiang, M. C., Chang, W. A., Tien, T. L., Huang, C. Y., Wu, W. W., Chia, W. T. & Sung, H. W., 2021, (Accepted/In press) In: ACS Nano. 15, 4, p. 7596-7607 12 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

  Tang, S. E., Liao, W. I., Pao, H. P., Hsu, C. W., Wu, S. Y., Huang, K. L. & Chu, S. J., Jul 15 2021, In: Frontiers in Pharmacology. 12, 650573.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Polygenic panels predicting the susceptibility of multiple upper aerodigestive tract cancer in oral cancer patients

  Chien, H. T., Yeh, C. C., Young, C. K., Chen, T. P., Liao, C. T., Wang, H. M., Cho, K. L. & Huang, S. F., May 2021, In: Journal of Personalized Medicine. 11, 5, 425.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use

  Otomo, N., Lu, H. F., Koido, M., Kou, I., Takeda, K., Momozawa, Y., Kubo, M., Kamatani, Y., Ogura, Y., Takahashi, Y., Nakajima, M., Minami, S., Uno, K., Kawakami, N., Ito, M., Sato, T., Watanabe, K., Kaito, T., Yanagida, H., Taneichi, H. & 30 others, Harimaya, K., Taniguchi, Y., Shigematsu, H., Iida, T., Demura, S., Sugawara, R., Fujita, N., Yagi, M., Okada, E., Hosogane, N., Kono, K., Nakamura, M., Chiba, K., Kotani, T., Sakuma, T., Akazawa, T., Suzuki, T., Nishida, K., Kakutani, K., Tsuji, T., Sudo, H., Iwata, A., Kaneko, K., Inami, S., Kochi, Y., Chang, W. C., Matsumoto, M., Watanabe, K., Ikegawa, S. & Terao, C., Aug 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1481-1491 11 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Polyketides with Anti-neuroinflammatory Activity fromTheissenia cinerea

  Hsieh, M. H., Hsiao, G., Chang, C. H., Yang, Y. L., Ju, Y. M., Kuo, Y. H. & Lee, T. H., Jul 23 2021, In: Journal of Natural Products. 84, 7, p. 1898-1903 6 p.

  Research output: Contribution to journal › Review article › peer-review
  3 Citations (Scopus)

• Pomelo fruit wastes are potentially valuable antioxidants, anti-inflammatories, antihypertensives, and antihyperglycemics

  Lin, L. Y., Huang, C. Y., Chen, K. C. & Peng, R. Y., 2021, (Accepted/In press) In: Horticulture Environment and Biotechnology.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Population-based study on the all-cause and cause-specific risks of mortality among long-term opioid analgesics users without cancer in Taiwan

  Lee, P. F., Li, C. Y., Liu, Y. C., Chiu, C. T. & Hou, W. H., Nov 2021, In: Healthcare (Switzerland). 9, 11, 1402.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Porphyromonas gingivalis induces proinflammatory cytokine expression leading to apoptotic death through the oxidative stress/nf‐κb pathway in brain endothelial cells

  Charoensaensuk, V., Chen, Y. C., Lin, Y. H., Ou, K. L., Yang, L. Y. & Lu, D. Y., Nov 2021, In: Cells. 10, 11, 3033.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves’ disease

  Cheng, C. W., Fang, W. F., Tang, K. T. & Lin, J. D., Dec 2021, In: Scientific Reports. 11, 1, 21350.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Post-cardiac arrest care and targeted temperature management: A consensus of scientific statement from the Taiwan Society of Emergency & Critical Care Medicine, Taiwan Society of Critical Care Medicine and Taiwan Society of Emergency Medicine

  Chiu, W. T., Lin, K. C., Tsai, M. S., Hsu, C. H., Wang, C. H., Kuo, L. K., Chien, Y. S., Wu, C. H., Lai, C. H., Huang, W. C., Wang, C. H., Wang, T. L., Hsu, H. H., Lin, J. J., Hwang, J. J., Ng, C. J., Choi, W. M. & Huang, C. H., Jan 2021, In: Journal of the Formosan Medical Association. 120, 1P3, p. 569-587 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Postconcussion Symptoms After an Uncomplicated Mild Traumatic Brain Injury in Older Adults: Frequency, Risk Factors, and Impact on Quality of Life

  Chung, J-W., Liu, D., Wei, L., Wen, Y-T., Lin, H-Y., Chen, H-C. & Chiu, H-Y., Oct 25 2021, (E-pub ahead of print) In: The Journal of head trauma rehabilitation.

  Research output: Contribution to journal › Article › peer-review

• Posterior circulation acute stroke prognosis early CT scores in predicting functional outcomes: A meta-analysis

  Lu, W. Z., Lin, H. A., Bai, C. H. & Lin, S. F., Feb 2021, In: PLoS ONE. 16, 2 February, e0246906.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Postoperative adjuvant dose-dense chemotherapy with bevacizumab and maintenance bevacizumab after neoadjuvant chemotherapy for advanced ovarian cancer: A phase II AGOG/TGOG trial

  Chou, H. H., Chen, W. C., Yang, L. Y., Huang, H. J., Chang, W. Y., Lin, H., Wu, R. C., Chen, M. Y., Qiu, J. T., Huang, K. G., Chao, A., Chang, T. C. & Lai, C. H., Jul 2021, In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 262, p. 13-20 8 p.

  Research output: Contribution to journal › Article › peer-review