Find Research Outputs

2019

Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma

Suk, F. M., Liu, C. L., Hsu, M. H., Chuang, Y. T., Wang, J. P. & Liao, Y. J., Dec 1 2019, In : Scientific Reports. 9, 1, 17259.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Therapeutics
Epithelial-Mesenchymal Transition
Heterografts
Glypicans
6 Citations (Scopus)

Triple-negative breast cancer: Current understanding and future therapeutic breakthrough targeting cancer stemness

Lee, K. L., Kuo, Y. C., Ho, Y. S. & Huang, Y. H., Sep 2019, In : Cancers. 11, 9, 1334.

Research output: Contribution to journalReview article

Open Access
Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Neoplasms
Therapeutics
Breast Neoplasms

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

Wong, J. Y. Y., Zhang, H., Hsiung, C. A., Shiraishi, K., Yu, K., Matsuo, K., Wong, M. P., Hong, Y. C., Wang, J., Seow, W. J., Wang, Z., Song, M., Kim, H. N., Chang, I. S., Chatterjee, N., Hu, W., Wu, C., Mitsudomi, T., Zheng, W., Kim, J. H. & 166 others, Seow, A., Caporaso, N. E., Shin, M. H., Chung, L. P., An, S. J., Wang, P., Yang, Y., Zheng, H., Yatabe, Y., Zhang, X. C., Kim, Y. T., Cai, Q., Yin, Z., Kim, Y. C., Bassig, B. A., Chang, J., Ho, J., Ji, B. T., Daigo, Y., Ito, H., Momozawa, Y., Ashikawa, K., Kamatani, Y., Honda, T., Hosgood, H. D., Sakamoto, H., Kunitoh, H., Tsuta, K., Watanabe, S. I., Kubo, M., Miyagi, Y., Nakayama, H., Matsumoto, S., Tsuboi, M., Goto, K., Shi, J., Song, L., Hua, X., Takahashi, A., Goto, A., Minamiya, Y., Shimizu, K., Tanaka, K., Wei, F., Matsuda, F., Su, J., Kim, Y. H., Oh, I. J., Song, F., Su, W. C., Chen, Y. M., Chang, G. C., Chen, K. Y., Huang, M. S., Chien, L. H., Xiang, Y. B., Park, J. Y., Kweon, S. S., Chen, C. J., Lee, K. M., Blechter, B., Li, H., Gao, Y. T., Qian, B., Lu, D., Liu, J., Jeon, H. S., Hsiao, C. F., Sung, J. S., Tsai, Y. H., Jung, Y. J., Guo, H., Hu, Z., Wang, W. C., Chung, C. C., Burdett, L., Yeager, M., Hutchinson, A., Berndt, S. I., Wu, W., Pang, H., Li, Y., Choi, J. E., Park, K. H., Sung, S. W., Liu, L., Kang, C. H., Zhu, M., Chen, C. H., Yang, T. Y., Xu, J., Guan, P., Tan, W., Wang, C. L., Hsin, M., Sit, K. Y., Ho, J., Chen, Y., Choi, Y. Y., Hung, J. Y., Kim, J. S., Yoon, H. I., Lin, C. C., Park, I. K., Xu, P., Wang, Y., He, Q., Perng, R. P., Chen, C. Y., Vermeulen, R., Wu, J., Lim, W. Y., Chen, K. C., Li, Y. J., Li, J., Chen, H., Yu, C. J., Jin, L., Chen, T. Y., Jiang, S. S., Liu, J., Yamaji, T., Hicks, B., Wyatt, K., Li, S. A., Dai, J., Ma, H., Jin, G., Song, B., Wang, Z., Cheng, S., Li, X., Ren, Y., Cui, P., Iwasaki, M., Shimazu, T., Tsugane, S., Zhu, J., Yang, K., Jiang, G., Fei, K., Wu, G., Lin, H. C., Chen, H. L., Fang, Y. H., Tsai, F. Y., Hsieh, W. S., Yu, J., Stevens, V. L., Laird-Offringa, I. A., Marconett, C. N., Rieswijk, L., Chao, A., Yang, P. C., Shu, X. O., Wu, T., Wu, Y. L., Lin, D., Chen, K., Zhou, B., Huang, Y. C., Kohno, T., Shen, H., Chanock, S. J., Rothman, N. & Lan, Q., Jan 1 2019, In : Genomics.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Genome-Wide Association Study
Tuberculosis
Smoking
Infection

Tumor suppressor gene glycine N-methyltransferase and its potential in liver disorders and hepatocellular carcinoma

Chen, M., Yang, M. H., Chang, M. M., Tyan, Y. C. & Chen, Y. M. A., Sep 1 2019, In : Toxicology and Applied Pharmacology. 378, 114607.

Research output: Contribution to journalReview article

Glycine N-Methyltransferase
Tumor Suppressor Genes
Liver
Tumors
Hepatocellular Carcinoma
international law
Genes
stakeholder
Population
ability

Two-vessel occlusion mouse model of cerebral ischemia-reperfusion

Chen, C. Y., Chen, R. J. & Lee, G. A., Mar 1 2019, In : Journal of Visualized Experiments. 2019, 145, e59078.

Research output: Contribution to journalArticle

Brain Ischemia
Reperfusion
Middle Cerebral Artery Infarction
Middle Cerebral Artery
Blood
2 Citations (Scopus)

Ultra-narrow band blue emission of Eu2+ in halogenated (Alumino)borate systems based on high lattice symmetry

Wei, Y., Qu, X., Li, G., Cheng, Z., Molokeev, M. S., Lin, C. C., Chan, T. S., Chang, C. K., Chuang, Y. C. & Lin, J., Jan 1 2019, In : Journal of the American Ceramic Society.

Research output: Contribution to journalArticle

Borates
Phosphors
Display devices
Color
Quantum efficiency

Ultrasound-assisted synthesis of thermosensitive nanovesicle for direct trap and release of analgesic drugs in biofluid and sewage

Lee, Y. C., Hsieh, C. M., Tsai, T. N., Yang, D. P. & Chen, P. S., Jun 1 2019, In : Ultrasonics Sonochemistry. 54, p. 61-67 7 p.

Research output: Contribution to journalArticle

sewage
Sonication
urine
Sewage
Acetaminophen

Ultrasound-Guided Minimally Invasive Surgical Resection of Retrocalcaneal Bursitis: A Preliminary Comparison With Traditional Open Surgery

Wang, C. L., Chen, P. Y., Yang, K. C., Wu, H. C. & Wang, C. C., Sep 2019, In : Journal of Foot and Ankle Surgery. 58, 5, p. 855-860 6 p.

Research output: Contribution to journalArticle

Bursitis
Minimally Invasive Surgical Procedures
Pain
Heel
Ankle
12 Citations (Scopus)

Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer

Nguyen, T., Kirsch, B. J., Asaka, R., Nabi, K., Quinones, A., Tan, J., Antonio, M. J., Camelo, F., Li, T., Nguyen, S., Hoang, G., Nguyen, K., Udupa, S., Sazeides, C., Shen, Y-A., Elgogary, A., Reyes, J., Zhao, L., Kleensang, A., Chaichana, K. L. & 7 others, Hartung, T., Betenbaugh, M. J., Marie, S. K., Jung, J. G., Wang, T-L., Gabrielson, E. & Le, A., Apr 9 2019, In : Cell Reports. 27, 2, p. 491-501.e6

Research output: Contribution to journalArticle

Glutamate Carboxypeptidase II
Glutamic Acid
Glutaminase
Neoplasms
Neurotransmitter Agents

Unsupervised Classification of Cerebrospinal Fluid by Statistical Indicators

Lee, K. R., Yeh, Y. X., Wu, C. C., Lin, J. & Chiang, Y. H., Jan 16 2019, Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc., p. 3827-3832 6 p. 8616645. (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Cerebrospinal fluid
Cerebrospinal Fluid
Spinal Stenosis
Spinal Canal
Canals
2 Citations (Scopus)

Unveiling the Nanoparticle-Seeded Catalytic Nucleation Kinetics of Perovskite Solar Cells by Time-Resolved GIXS

Lin, C. Y., Li, S. S., Chang, J. W., Chia, H. C., Hsiao, Y. Y., Su, C. J., Lian, B. J., Wen, C. Y., Huang, S. K., Wu, W. R., Wang, D. Y., Su, A. C., Chen, C. W. & Jeng, U. S., Jan 1 2019, In : Advanced Functional Materials. 1902582.

Research output: Contribution to journalArticle

Perovskite
Nucleation
solar cells
nucleation
nanocrystals
1 Citation (Scopus)

Upregulation of IGF-IIRα intensifies doxorubicin-induced cardiac damage

Pandey, S., Kuo, W. W., Ho, T. J., Yeh, Y. L., Shen, C. Y., Chen, R. J., Chang, R. L., Pai, P. Y., Padma, V. V., Huang, C. Y. & Huang, C. Y., Jan 1 2019, In : Journal of Cellular Biochemistry. 120, 10, p. 16956-16966 11 p.

Research output: Contribution to journalArticle

Doxorubicin
Up-Regulation
Cardiomegaly
Heat-Shock Proteins
Proteins
1 Citation (Scopus)

Urinary thiodiglycolic acid is associated with increased risk of non-alcoholic fatty liver disease in children living near a petrochemical complex

Wang, C. W., Chuang, H. Y., Liao, K. W., Yu, M. L., Dai, C. Y., Chang, W. T., Tsai, C. H., Chiang, H. C. & Huang, P. C., Oct 1 2019, In : Environment International. 131, 104978.

Research output: Contribution to journalArticle

Open Access
acid
confidence interval
serum
chloride
petrochemical
1 Citation (Scopus)
Dental Pulp
p38 Mitogen-Activated Protein Kinases
Dentin
Magnetic Fields
Stem Cells
1 Citation (Scopus)

Use of lipid-lowering agents is not associated with improved outcomes for tuberculosis patients on standard-course therapy: A population-based cohort study

Chen, Y. T., Kuo, S. C., Chao, P. W. & Chang, Y. Y., Jan 1 2019, In : PLoS One. 14, 1, e0210479.

Research output: Contribution to journalArticle

antilipemic agents
Fibric Acids
Hydroxymethylglutaryl-CoA Reductase Inhibitors
cohort studies
tuberculosis

Using artificial neural network to predict functional recovery of patients treated by intravenous thrombolysis in acute ischemic stroke

Chiu, H. W., Huang, Y. T. & Cheng, C. A., Jan 1 2019, In : IFMBE Proceedings. 68, 1, p. 331-334 4 p.

Research output: Contribution to journalConference article

Neural networks
Recovery
Emergency rooms
Neurons
Medicine
1 Citation (Scopus)

Using high-throughput transcriptome sequencing to investigate the biotransformation mechanism of hexabromocyclododecane with Rhodopseudomonas palustris in water

Wang, R., Lin, C. Y., Chen, S. H., Lo, K. J., Liu, C. T., Chou, T. H. & Shih, Y. H., Nov 20 2019, In : Science of the Total Environment. 692, p. 249-258 10 p.

Research output: Contribution to journalArticle

biotransformation
Genes
Throughput
Water
gene

Using the OVAKO working posture analysis system in cleaning occupations

Wang, M. H., Chen, Y. L. & Chiou, W. K., Nov 21 2019, In : Work. 64, 3, p. 613-621 9 p.

Research output: Contribution to journalArticle

Posture
Occupations
Body Regions
Occupational Health
Elbow
3 Citations (Scopus)

Using two-dimensional convolutional neural networks for identifying GTP binding sites in Rab proteins

Le, N. Q. K., Ho, Q. T. & Ou, Y. Y., Feb 1 2019, In : Journal of Bioinformatics and Computational Biology. 17, 1, 1950005.

Research output: Contribution to journalArticle

Binding sites
Guanosine Triphosphate
Binding Sites
Learning
Neural networks
1 Citation (Scopus)

Using word embedding technique to efficiently represent protein sequences for identifying substrate specificities of transporters

Nguyen, T. T. D., Le, N. Q. K., Ho, Q. T., Phan, D. V. & Ou, Y. Y., Jul 15 2019, In : Analytical Biochemistry. 577, p. 73-81 9 p.

Research output: Contribution to journalArticle

Substrate Specificity
Substrates
Natural Language Processing
Proteins
Membrane Transport Proteins
Schizophrenia
Appointments and Schedules
Disabled Persons
Cognition
Taiwan

Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study

Chou, Y. C., You, S. L., Bai, C. H., Liao, Y. C., Wei, C. Y. & Sun, C. A., Jan 1 2019, In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Open Access
Apolipoproteins
Apolipoproteins B
Type 2 Diabetes Mellitus
Cohort Studies
Apolipoprotein A-I
2 Citations (Scopus)

Utilizing proteomic approach to identify nuclear translocation related serine kinase phosphorylation site of GNMT as downstream effector for benzo[a]pyrene

Yang, M. H., Liao, C. C., Hung, J. H., Lai, X. T., Yen, C. H. & Chen, Y. M. A., Apr 1 2019, In : Journal of Food and Drug Analysis. 27, 2, p. 603-609 7 p.

Research output: Contribution to journalArticle

Open Access
glycine N-methyltransferase
Glycine N-Methyltransferase
Protein-Serine-Threonine Kinases
Benzo(a)pyrene
Proteomics

Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH

Chang, H. W., Yang, C. H., Luo, Y. C., Su, B. G., Cheng, H. Y., Tung, S. Y., Carillo, K. J. D., Liao, Y. T., Tzou, D. L. M., Wang, H. C. & Chang, W., Jun 1 2019, In : PLoS Pathogens. 15, 6, e1007826.

Research output: Contribution to journalArticle

Open Access
faropenem medoxomil
Vaccinia
Virus Internalization
Viral Proteins
Membrane Fusion

Validation and evaluation of the Mandarin version of the oral health literacy adult questionnaire in Taiwan

Ho, M. H., Montayre, J., Chang, H. C., Joo, J. Y., Naghibi Sistani, M. M., Lin, Y. K., Traynor, V., Chang, C. C. & Liu, M. F., Jan 1 2019, (Accepted/In press) In : Public Health Nursing.

Research output: Contribution to journalArticle

Health Literacy
Oral Health
Taiwan
Psychometrics
Reproducibility of Results

Validation of the Short-Form Health Literacy Questionnaire (HLS-SF12) and Its Determinants among People Living in Rural Areas in Vietnam

Duong, T. V., Nguyen, T. T. P., Pham, K. M., Nguyen, K. T., Giap, M. H., Tran, T. D. X., Nguyen, C. X., Yang, S. H. & Su, C. T., Sep 1 2019, In : International Journal of Environmental Research and Public Health. 16, 18, p. 3346 3346.

Research output: Contribution to journalArticle

Open Access
Health Literacy
Vietnam
Surveys and Questionnaires
Aptitude
Health

Validation of the World Health Organization Disability Assessment Schedule 2.0 in adults with spinal cord injury in Taiwan: a psychometric study

Chiu, T. Y., Finger, M. E., Fellinghauer, C. S., Escorpizo, R., Chi, W. C., Liou, T. H. & Yen, C. F., Jan 1 2019, (Accepted/In press) In : Spinal Cord.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Taiwan
Psychometrics
Appointments and Schedules
Statistical Factor Analysis
Reproducibility of Results
Language
Psychometrics
Taiwan
Statistical Factor Analysis
2 Citations (Scopus)

Viral safety of human platelet lysate for cell therapy and regenerative medicine: Moving forward, yes, but without forgetting the past

Burnouf, T., Barro, L., Nebie, O., Wu, Y. W., Goubran, H., Knutson, F. & Seghatchian, J., Dec 2019, In : Transfusion and Apheresis Science. 58, 6, 102674.

Research output: Contribution to journalReview article

Regenerative Medicine
Cell- and Tissue-Based Therapy
Blood Platelets
Safety
Inborn Genetic Diseases
1 Citation (Scopus)

Virtual reality among the elderly: A usefulness and acceptance study from Taiwan

Syed-Abdul, S., Malwade, S., Nursetyo, A. A., Sood, M., Bhatia, M., Barsasella, D., Liu, M. F., Chang, C. C., Srinivasan, K., Raja, M. & Li, Y. C. J., Aug 19 2019, In : BMC Geriatrics. 19, 1, 223.

Research output: Contribution to journalArticle

Open Access
Taiwan
Technology
Population
Linear Models
Mental Health
1 Citation (Scopus)

Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease

Lai, J. H., Chen, K. Y., Wu, J. C. C., Olson, L., Brené, S., Huang, C. Z., Chen, Y. H., Kang, S. J., Ma, K. H., Hoffer, B. J., Hsieh, T. H. & Chiang, Y. H., Oct 1 2019, In : Brain Research. 1720, 146301.

Research output: Contribution to journalReview article

Open Access
Parkinson Disease
Dopamine
Exercise
Dopamine Plasma Membrane Transport Proteins
Membrane Transport Proteins

Walking against or with traffic? Evaluating pedestrian fatalities and head injuries in Taiwan

Pai, C. W., Chen, P. L., Ma, S. T., Wu, S. H., Linkov, V. & Ma, H. P., Oct 10 2019, In : BMC Public Health. 19, 1, 1 p.

Research output: Contribution to journalArticle

Taiwan
Craniocerebral Trauma
Walking
Logistic Models
Pedestrians

Walking is more effective than yoga at reducing sleep disturbance in cancer patients: A systematic review and meta-analysis of randomized controlled trials

Tang, M. F., Chiu, H. Y., Xu, X., Kwok, J. Y., Cheung, D. S. T., Chen, C. Y. & Lin, C. C., Oct 1 2019, In : Sleep Medicine Reviews. 47, p. 1-8 8 p.

Research output: Contribution to journalReview article

Yoga
Walking
Meta-Analysis
Sleep
Randomized Controlled Trials

Wasted Ganoderma tsugae derived chitosans for smear layer removal in endodontic treatment

Huang, S. T., Teng, N. C., Wang, H. H., Hsieh, S. C. & Yang, J. C., Nov 1 2019, In : Polymers. 11, 11, 1795.

Research output: Contribution to journalArticle

Open Access
Chitosan
Polysaccharides
Chelation
Ethylenediaminetetraacetic acid
Alkalies

Water exchange colonoscopy decreased adenoma miss rates compared with literature data and local data with CO2 insufflation: An observational study

Cheng, C. L., Kuo, Y. L., Hsieh, Y. H., Tang, J-H. & Leung, F. W., Aug 14 2019, In : BMC Gastroenterology. 19, 1, 143.

Research output: Contribution to journalArticle

Open Access
Insufflation
Colonoscopy
Adenoma
Observational Studies
Water

Water-Soluble Fullerenol C60(OH)36 toward Effective Anti-Air Pollution Induced by Urban Particulate Matter in HaCaT Cell

Lee, C. W., Chi, M. C., Peng, K. T., Chiang, Y. C., Hsu, L. F., Yan, Y. L., Li, H. Y., Chen, M. C., Lee, I. T. & Lai, C. H., Aug 30 2019, In : International Journal of Molecular Sciences. 20, 17

Research output: Contribution to journalArticle

Open Access
air pollution
Particulate Matter
Air Pollution
Fullerenes
Air pollution

Weak coupling between intracellular feedback loops explains dissociation of clock gene dynamics

Schmal, C., Ono, D., Myung, J., Pett, J. P., Honma, S., Honma, K. I., Herzel, H. & Tokuda, I. T., Sep 12 2019, In : PLoS Computational Biology. 15, 9, p. e1007330 e1007330.

Research output: Contribution to journalArticle

Open Access
circadian rhythm
Weak Coupling
Feedback Loop
gene expression
Clocks

Web-based intervention to promote physical activity in Taiwanese children

Huang, S. J., Hung, W. C., Shyu, M. L., Chang, K. C. & Chen, C. K., Mar 1 2019, In : Journal of Pediatric Nursing. 45, p. e35-e43 9 p.

Research output: Contribution to journalArticle

Self Care
Exercise
Self Efficacy
Students
Geographic Information Systems
1 Citation (Scopus)

Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication: A comparison

Wang, W., Fann, C. S. J., Yang, S. H., Chen, H. H. & Chen, C. Y., Jan 1 2019, In : Nutrition. 57, p. 290-299 10 p.

Research output: Contribution to journalArticle

Weight Loss
Stomach
Blood Pressure
Triglycerides
Body Mass Index

Where and How Centenarians Die? The Role of Hospice Care

Chen, Y. C., Hu, H. Y., Fan, H. Y., Kao, W. S., Chen, H. Y. & Huang, S. J., Dec 1 2019, In : American Journal of Hospice and Palliative Medicine. 36, 12, p. 1068-1075 8 p.

Research output: Contribution to journalArticle

Hospice Care
Cause of Death
Home Care Services
National Health Programs
Pneumonia
1 Citation (Scopus)

White sweet potato as meal replacement for overweight white-collar workers: A randomized controlled trial

Shih, C. K., Chen, C. M., Hsiao, T. J., Liu, C. W. & Li, S. C., Jan 1 2019, In : Nutrients. 11, 1, 165.

Research output: Contribution to journalArticle

Open Access
Ipomoea batatas
collars
sweet potatoes
Meals
arm circumference
Institutionalization
Appointments and Schedules
Long-Term Care
ROC Curve
Logistic Models

Why context matters? Divisive normalization and canonical microcircuits in psychiatric disorders

Northoff, G. & Mushiake, H., Jan 1 2019, (Accepted/In press) In : Neuroscience Research.

Research output: Contribution to journalReview article

Open Access
Psychiatry
Schizophrenia
Depression
2 Citations (Scopus)

Working with mental models to learn and visualize a new reaction mechanism

Bongers, A., Northoff, G. & Flynn, A. B., Apr 2019, In : Chemistry Education Research and Practice.

Research output: Contribution to journalArticle

chemistry
Students
teaching research
student
Epoxy Compounds
9 Citations (Scopus)

Workplace justice and intention to leave the nursing profession

Chin, W., Guo, Y. L. L., Hung, Y. J., Hsieh, Y. T., Wang, L. J. & Shiao, J. S. C., Feb 1 2019, In : Nursing Ethics. 26, 1, p. 307-319 13 p.

Research output: Contribution to journalArticle

Social Justice
Workplace
Nursing
Nurses
Taiwan
1 Citation (Scopus)
Open Access
biomarkers
Castration
Androgen Receptors
Biomarkers
Prostatic Neoplasms
5 Citations (Scopus)

ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer

Mase, S., Shinjo, K., Totani, H., Katsushima, K., Arakawa, A., Takahashi, S., Lai, H. C., Lin, R. I., Chan, M. W. Y., Sugiura-Ogasawara, M. & Kondo, Y., Mar 1 2019, In : Cancer Science. 110, 3, p. 1105-1116 12 p.

Research output: Contribution to journalArticle

Open Access
DNA Methylation
Ovarian Neoplasms
Recurrence
Platinum
Atlases
1 Citation (Scopus)
Precision Medicine
Psychiatry