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Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway

Lin, H., Li, H. F., Chen, H-H., Lai, P. F., Juan, S-H., Chen, J. J. & Cheng, C. F., 2014, In : Molecular Pharmacology. 85, 5, p. 682-691 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Activation and induction of cytosolic phospholipase A2 by IL-1β in human tracheal smooth muscle cells: Role of MAPKs/p300 and NF-κB

Lee, C. W., Lee, I. T., Lin, C. C., Lee, H. C., Lin, W. N. & Yang, C. M., Apr 1 2010, In : Journal of Cellular Biochemistry. 109, 5, p. 1045-1056 12 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells

Lee, C-W., Lin, C-C., Lee, I-T., Lee, H-C. & Yang, C-M., Aug 2011, In : Journal of Cellular Physiology. 226, 8, p. 2103-14 12 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Activation and up-regulation of nitric oxide synthase in human umbilical vein endothelial cells by polycyclic aromatic hydrocarbons

Li, C. H., Lee, C. C., Cheng, Y. W., Juang, H. A. & Kang, J. J., Jul 15 2004, In : Toxicology Letters. 151, 2, p. 367-374 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
23 Citations (Scopus)

Activation of a novel ubiquitin-independent proteasome pathway when RNA polymerase II encounters a protein roadblock

Ban, Y., Ho, C. W., Lin, R. K., Lyu, Y. L. & Liu, L-F., 2013, In : Molecular and Cellular Biology. 33, 20, p. 4008-4016 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Activation of a nuclear factor of activated T-lymphocyte-3 (NFAT3) by oxidative stress in carboplatin-mediated renal apoptosis

Lin, H., Sue, Y. M., Chou, Y., Cheng, C. F., Chang, C. C., Li, H. F., Chen, C. C. & Juan, S. H., Dec 2010, In : British Journal of Pharmacology. 161, 7, p. 1661-1676 16 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Activation of brainstem catecholaminergic neurons by conditioned and unconditioned aversive stimuli as revealed by c-Fos immunoreactivity

Pezzone, M. A., Lee, W. S., Hoffman, G. E., Pezzone, K. M. & Rabin, B. S., Apr 16 1993, In : Brain Research. 608, 2, p. 310-318 9 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)

Activation of CDC 25 phosphatase and CDC 2 kinase involved in GL331- induced apoptosis

Huang, T. S., Shu, C. H., Yang, W. K. & Whang-Peng, J., Jul 15 1997, In : Cancer Research. 57, 14, p. 2974-2978 5 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Activation of c-Jun NH2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor β-lapachone-induced apoptosis through an oxidation-dependent pathway

Shiah, S. G., Chuang, S. E., Chau, Y. P., Shen, S. C. & Kuo, M. L., Jan 16 1999, In : Cancer Research. 59, 2, p. 391-398 8 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice

Yang, P. P., Yeh, G. C., Yeh, T. K., Xi, J., Loh, H. H., Law, P. Y. & Tao, P. L., Sep 1 2016, In : Pharmacological Research. 111, p. 867-876 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Activation of DNA methyltransferase 1 by EBV LMP1 involves c-Jun NH 2-terminal kinase signaling

Tsai, C. L., Li, H. P., Lu, Y. J., Hsueh, C., Liang, Y., Chen, C. L., Tsao, S. W., Tse, K. P., Yu, J. S. & Chang, Y. S., Dec 15 2006, In : Cancer Research. 66, 24, p. 11668-11676 9 p.

Research output: Contribution to journalArticle

153 Citations (Scopus)

Activation of dopamine D2-like receptors attenuates pulmonary C-fiber hypersensitivity in rats

Lin, Y. S., Gu, Q. & Lee, L. Y., Apr 15 2003, In : American Journal of Respiratory and Critical Care Medicine. 167, 8, p. 1096-1101 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways

Deng, J. Y., Hsieh, P. S., Huang, J. P., Lu, L. S. & Hung, L. M., Jul 2008, In : Diabetes. 57, 7, p. 1814-1823 10 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Activation of estrogen receptors with E2 downregulates peroxisome proliferator-activated receptor γ in hepatocellular carcinoma

Lin, Y. M., Velmurugan, B. K., Yeh, Y. L., Tu, C. C., Ho, T. J., Lai, T-I., Tsai, C. H., Tsai, F. J., Tsai, C. H. & Huang, C. Y., Dec 2013, In : Oncology Reports. 30, 6, p. 3027-3031 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1

Kawaguchi, M., Onuchic, L. F. & Huang, S. K., May 3 2002, In : Journal of Biological Chemistry. 277, 18, p. 15229-15232 4 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
33 Citations (Scopus)

Activation of fibroblast growth factor 8 gene expression in human embryonal carcinoma cells

Wu, J., Payson, R. A., Lang, J. C. & Chiu, I. M., May 1997, In : Journal of Steroid Biochemistry and Molecular Biology. 62, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells

Chen, P. C., Lee, W. Y., Ling, H. H., Cheng, C. H., Chen, K. C. & Lin, C. W., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Activation of free fatty acid receptor 1 improves hepatic steatosis through a p38-dependent pathway

Ou, H. Y., Wu, H. T., Lu, F. H., Su, Y. C., Hung, H. C., Wu, J. S., Yang, Y. C., Wu, C. L. & Chang, C. J., Jul 9 2014, In : Journal of Molecular Endocrinology. 53, 2, p. 165-174 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Activation of gonadotropin-releasing hormone receptors produces neuronal excitation in the rat hippocampus

Lu, F., Yang, J. M., Wu, J. N., Chen, Y. C., Kao, Y. H., Tung, C. S. & Yang, S. N., 1999, In : Chinese Journal of Physiology. 42, 2, p. 67-71 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Activation of heme oxygenase-1 by Ginkgo biloba extract differentially modulates endothelial and smooth muscle-like progenitor cells for vascular repair

Wu, T. C., Chen, J. S., Wang, C. H., Huang, P. H., Lin, F. Y., Lin, L. Y., Lin, S. J. & Chen, J. W., Dec 1 2019, In : Scientific Reports. 9, 1, 17316.

Research output: Contribution to journalArticle

Open Access
155 Citations (Scopus)

Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone

Huang, H. S., Chiou, J. F., Fong, Y., Hou, C. C., Lu, Y. C., Wang, J. Y., Shih, J. W., Pan, Y. R. & Lin, J. J., Jul 17 2003, In : Journal of Medicinal Chemistry. 46, 15, p. 3300-3307 8 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Activation of IGF-I survival signaling and its compensative inhibition of the cardiac apoptosis on carotid arteries balloon-injured rat hearts

Hsieh, C. H., Pai, P., Wu, J. P., Ho, T. J., Wu, C. H., Shibu, M. A., Day, C. H., Viswanadha, V. P., Chuang, H. L. & Huang, C. Y., 2017, In : Chinese Journal of Physiology. 60, 3, p. 166-173 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Activation of IL6/IGFIR confers poor prognosis of HBV-related hepatocellular carcinoma through induction of OCT4/NANOG expression

Chang, T. S., Wu, Y. C., Chi, C. C., Su, W. C., Chang, P. J., Lee, K. F., Tung, T. H., Wang, J., Liu, J-J., Tung, S. Y., Kuo, L. M., Ho, H. N., Ling, T. Y. & Huang, Y-H., Jan 1 2015, In : Clinical Cancer Research. 21, 1, p. 201-210 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C2C12 cells

Lui, T. N., Tsao, C. W., Huang, S. Y., Chang, C. H. & Cheng, J. T., May 2010, In : Neuroscience Letters. 474, 3, p. 144-147 4 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Activation of indices of cell-mediated immunity in bipolar mania

Tsai, S. Y., Chen, K. P., Yang, Y. Y., Chen, C. C., Lee, J. C., Singh, V. K. & Leu, S. J. C., Apr 15 1999, In : Biological Psychiatry. 45, 8, p. 989-994 6 p.

Research output: Contribution to journalArticle

98 Citations (Scopus)

Activation of iodosobenzene by catalytic tetrabutylammonium iodide and its application in the oxidation of some isoquinoline alkaloids

Huang, W. J., Singh, O. V., Chen, C. H., Chiou, S. Y. & Lee, S. S., 2002, In : Helvetica Chimica Acta. 85, 4, p. 1069-1078 10 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Activation of JNK contributes to evodiamine-induced apoptosis and G 2/M arrest in human colorectal carcinoma cells: A structure-activity study of evodiamine

Chien, C. C., Wu, M. S., Shen, S. C., Ko, C. H., Chen, C. H., Yang, L. L. & Chen, Y. C., Jun 24 2014, In : PLoS One. 9, 6, e99729.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish Application of Zebrafish in Biomedical Research

Chou, C. M., Chen, Y. C., Su, S., Chen, G. D., Huang, K. Y., Lien, H. W., Huang, C. J. & Cheng, C. H., Nov 17 2015, In : Journal of Biomedical Science. 22, 1, 102.

Research output: Contribution to journalArticle

Activation of mitogen-activated protein kinase by oxidized low-density lipoprotein in canine cultured vascular smooth muscle cells

Yang, C. M., Chiu, C. T., Wang, C. C., Chien, C. S., Hsiao, L. D., Lin, C. C., Tu, M. T. & Pan, S. L., Apr 2000, In : Cellular Signalling. 12, 4, p. 205-214 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Activation of muscarinic M-3 receptor may decrease glucose uptake and lipolysis in adipose tissue of rats

Yang, T. T., Chang, C. K., Tsao, C. W., Hsu, Y. M., Hsu, C. T. & Cheng, J. T., Feb 13 2009, In : Neuroscience Letters. 451, 1, p. 57-59 3 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression

Chen, P. M., Wu, T. C., Wang, Y. C., Cheng, Y. W., Sheu, G. T., Chen, C. Y. & Lee, H., Nov 2013, In : Carcinogenesis. 34, 11, p. 2655-2663 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
21 Citations (Scopus)

Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

Cheng, Y. L., Lin, Y. S., Chen, C. L., Tsai, T. T., Tsai, C. C., Wu, Y. W., Ou, Y. D., Chu, Y. Y., Wang, J. M., Yu, C. Y. & Lin, C. F., Aug 26 2016, In : Scientific Reports. 6, 32000.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Activation of opioid μ-receptor by sinomenine in cell and mice

Wang, M. H., Chang, C. K., Cheng, J. H., Wu, H. T., Li, Y. X. & Cheng, J. T., Oct 10 2008, In : Neuroscience Letters. 443, 3, p. 209-212 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Activation of p38 MAPK-regulated Bcl-xL signaling increases survival against zoledronic acid-induced apoptosis in osteoclast precursors

Tai, T. W., Su, F. C., Chen, C. Y., Jou, I. M. & Lin, C. F., 2014, In : Bone. 67, p. 166-174 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia

Wen, Y-R., Suter, M. R., Ji, R. R., Yeh, G. C., Wu, Y. S., Wang, K. C., Kohno, T., Sun, W. Z. & Wang, C. C., Jan 2009, In : Anesthesiology. 110, 1, p. 155-165 11 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)
4 Citations (Scopus)

Activation of PERK contributes to apoptosis and G2/M arrest by microtubule disruptors in human colorectal carcinoma cells

Wu, M. S., Chien, C. C., Jargalsaikhan, G., Ilsan, N. A. & Chen, Y. C., Jan 2020, In : Cancers. 12, 1, 97.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Activation of phosphodiesterase IV during desensitization of the A(2A) adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells

Chang, Y. H., Conti, M., Lee, Y. C., Lai, H. L., Ching, Y. H. & Chern, Y., Sep 1997, In : Journal of Neurochemistry. 69, 3, p. 1300-1309 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., May 1 2013, In : Cellular Signalling. 25, 5, p. 1252-1263 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Activation of ROS/NF-κB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells

Luo, S. F., Chang, C. C., Lee, I-T., Lee, C. W., Lin, W. N., Lin, C. C. & Yang, C. M., May 15 2009, In : Toxicology and Applied Pharmacology. 237, 1, p. 8-21 14 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1

Chang, L. K., Chung, J. Y., Hong, Y. R., Ichimura, T., Nakao, M. & Liu, S. T., 2005, In : Nucleic Acids Research. 33, 20, p. 6528-6539 12 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Activation of telomerase and cyclooxygenase-2 in PDGF and FGF inhibition of C2-ceramide-induced apoptosis

Chien, C. C., Shen, S. C., Yang, L. Y., Wu, C. Y., Liau, J. S. & Chen, Y. C., Feb 2009, In : Journal of Cellular Physiology. 218, 2, p. 405-415 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Activation of the calcineurin-nuclear factor of activated T-cell signal transduction pathway in atrial fibrillation

Lin, C. C., Lin, J. L., Lin, C. S., Tsai, M. C., Su, M. J., Lai, L. P. & Stephen Huang, S. K., Jan 1 2004, In : Chest. 126, 6, p. 1926-1932 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Activation of the cellular oncogene c-erbB by ltr insertion: Molecular basis for induction of erythroblastosis by avian leukosis virus

Fung, Y. K. T., Lewis, W. G., Crittenden, L. B. & Kung, H. J., Jan 1 1983, In : Cell. 33, 2, p. 357-368 12 p.

Research output: Contribution to journalArticle

134 Citations (Scopus)