質子轉移反應質譜儀的原理與應用

Proton transfer reaction-mass spectrometer (PTR-MS) is capable of quantitatively on-line monitoring volatile organic compounds (VOCs). The fundamental difference between a conventional MS and PTR-MS is the ”soft ionization” method used by PTR-MS to ionize the organic molecules. The advantage of this method, besides immediately yielding absolute concentration, is that fragmentation of the molecules is very much reduced so the mass spectra produced are much easier to interpret and are more straightforward to quantify. This novel technique enables a variety of organic species in complex matrices to be monitored in real-time (within seconds), with detection limits as low as a few parts per trillion, volume (pptv). PTR-MS extend its applicability to broad fields such as environment analysis, food research, and medical application.