比例式輔助通氣模式對急性呼吸衰竭患者呼吸用力與呼吸型態之影響

Background: Proportional Pressure Support (PPS) is a new mode on EVITA-4 ventilator with a characteristic of Patient-orientated spontaneous breathing pattern. PPS amplify the ventilation in proportion to the patient's own effort. It is through volume assist (VA) and flow assist (FA) to decrease the elastic work and resistive work respectively. We are interested in the effort of PPS on breathing pattern and breathing effort. Method: The study was performed on 8 patients from mechanical ventilation on different support levels of PPS ventilation for 10 min with respiratory parameter measured by putting on esophageal balloon and pneumotachograph and connected to BICORE CP-100 monitor with MacLab for replay and analysis.
Result:(The form abridges) The breathing pattern stayed the same on different support levels of PPS. The desired minute ventilation, tidal volume and respiratory rate independent of the mechanical load. However, the breathing effort, presented by WOBp and PTP, had statistically significant difference.
Conclusion: These results demonstrate that PPS would not change breathing pattern, but can reduce in-spiratory effort.