The purpose of this study was to examine the body image change of heart transplant patients during exercise training. Both qualitative and quantitative methods were used in this study. Subjects were chosen by purposive sampling. The exercise training program was three times per week for 10 weeks. Data was collected by means of interview and the Body Cathexis Scale. Date was analyzed by content analysis, Friedman test, McNemar test, Mann-Whitney U test, and Kruskal-Wallis test. A total of ten valid cases were selected. The results of this study showed that the mean score of body image satisfaction was 2.47 before exercise training, 3.17 after 5 weeks, and 3.25 after 10 weeks of training. The scores at the fifth and the tenth weeks of exercise training were higher than those before training. Using content analysis to quantify the qualitative data, the most frequent dimension of body image was found to be the body function during exercise training. Base on the results of the study, it was concluded that satisfaction of body image was increased and a positive view of body image was enhanced during exercise training. The findings of this study will help nurses understand body image changes of heart transplant patients, provide suitable nursing intervention, and promote the quality of care.