To Study the Regulation of Macrophage Polarization and Disease Progression with Specific Haptoglobin Phenotypes in Patients with Chronic Obstructive Pulmonary Disease

Project: A - Government Institutionb - Ministry of Science and Technology

Project Details

StatusFinished
Effective start/end date8/1/197/31/20

Keywords

  • Haptoglobin
  • COPD
  • Hp1-1
  • Hp2-1
  • Hp2-2 phenotype
  • Hb
  • macrophage
  • macrophage polarization
  • classical activated M1 and alternative activated M2 macrophages
  • cytokine ((IL-1β;IL-6; IL-10; TNF-α; 8-isoprostane)
  • oxidative stress
  • Th1 cell immunity
  • Th2 cell immunity
  • phagocytosis
  • endocytosis
  • anti-oxidant
  • anti-inflammation
  • CD163 receptor
  • PBMC
  • lung biopsy
  • Bronchoalveolar Lavage
  • Flow Cytometry