Insomnia is the most common sleep complaint in adults. It is also a major public health problem. However, little is known about the cause and course of chronic insomnia for insomnia has been treated only as a symptom of other disorders, like depression for a long time. This grant proposal, with a case-control study design, will investigate the differences in psychological status, subjective and objective sleep measurements, emotional arousal response, and neuroimage between 60 patients with primary insomnia and their age- and gender-matched counterparts. All recruited subjects will be followed up in the successive two years to explore important factors associated with the outcome and comorbidity of primary insomnia.
|Effective start/end date||8/1/11 → 7/31/12|