In the past 10’s years, preserving the extraction socket and reduction the bone loss after extraction are the important issues in the dentistry. Following the consideration, bone grafting in the extraction socket is a common method for the purpose. Among the grafting materials, xenogenous graft showed good results in the clinic. However, the most popular xenogenous grafts are bovine bone grafts with the risk of Creutzfeldt-Jacob disease. Therefore, development of a novel xenogenous bone graft is necessary for the dentistry . In this study, a porcine based xenogenous bone graft will be mixed with different ratio porcine dermal collagen to develop a noval porcine bone-collagen composite. After the development, the properties tests and biocompatibility tests will be done for the safety. After the tests, implantation test will be arranged for the safety and efficiency evaluation in order to the clinical application.
|Effective start/end date||8/1/15 → 7/31/16|