Investigation of Itih-Interacting Proteome Networks and the Pathogenesis Mechanisms in Copd with Pm2.5 Exposure( I )

Project: A - Government Institutionb - Ministry of Science and Technology

Project Details

Description

本計畫將探討空汙PM2.5誘發COPD肺氣腫的詳細分子機制,尤其是ITIH蛋白與PM2.5和肺氣腫嚴重程度的關聯性,我們將從所構建之分子機制中找出具有潛力的蛋白質用於開發抗氣腫藥物。而我們所建立血清蛋白質體分析平台,將成為篩選具有不同臨床表現型COPD患者並監測其治療效果的主要工具。
StatusActive
Effective start/end date8/1/227/31/23

Keywords

  • chronic obstructive pulmonary disease
  • emphysema
  • inter-alpha-trypsin inhibitor heavy chain
  • mass spectrometry
  • proteomics
  • molecular mechanism
  • biomarker