Investigate the Regulatory Mechanism and Therapeutic Roles of Msn in Colorectal Cancer (Continuation Project)

Project: A - Government Institutionb - Ministry of Science and Technology

Project Details

Description

大腸直腸癌的盛行率和死亡率在全球及台灣ㄧ直居高不下,且其轉移及復發影響病人的整體存活率及無疾病存活率。MSN為連接細胞膜和細胞骨架的肌動蛋白並控制細胞形態,我們初步發現MSN參與大腸直腸癌疾病進程和治療反應,在本計畫中,我們將持續探討MSN在大腸直腸癌的角色和其訊息傳遞路徑。以期釐清MSN在大腸直腸癌的調控機制可提供將來一個大腸直腸癌新的治療方向。
StatusActive
Effective start/end date8/1/227/31/23

Keywords

  • Colorectal cancer
  • Moesin (MSN)
  • cell proliferation
  • metastasis
  • chemoresistance
  • radioresistance
  • apoptosis