Evaluate the Roles and Regulatory Mechanisms of Dicer-Mediated Adsl Expression in Chemosensitization of Dacarbazine and Potentially Combined Treatment with Minnelide in Melanoma

Project: A - Government Institutionb - Ministry of Science and Technology

Project Details

Description

這些具體的目的將有助於我們更好地釐清臨床上使用Dacarbazine治療黑色素瘤患者所產生的不敏感的分子機制,以及幫助我們闡明minnelide在黑色素瘤中是否具有抗腫瘤活性和化學增敏的潛力。本計畫中關於黑色素瘤藥物敏感度的影響及其相關機制,以及合併minnelide的潛在治療益處,也可以在未來發展診斷和抗癌藥物時提供更多的標的物。
StatusActive
Effective start/end date8/1/227/31/23

Keywords

  • MelanomaDacarbazine
  • Dacarbazine
  • Dicer
  • adenylosuccinate lyase (ADSL)
  • Minnelide