Acidic pharmaceuticals have been widely found in the environment. They may be toxic for human and aquatic species. Manganese dioxides are among the most important naturally occurring oxidants in facilitating organic pollutant transformation in soils and sediments and deserve particular attention due to their high reduction potentials. It is effective oxidants for a wide range of pollutants including phenols, chlorophenol and anilines. In this study, four acidic pharmaceuticals, diclofenac, ibuprofen, naproxen and ketoprofen will be investigated for reaction with manganese dioxides made by different methods. The effects of addition of adsorption assistants, oxidation assistants and energy such as microwave and supersonic wave on the reaction will also be investigated. An attenuated total reflectance-Fourier transform infrared spectrometer (ATR-FTIR) will be used to characterize the bonding of the adsorbents and the surface of manganese dioxides. The types of the products of degradation will be determined by a liquid chromatography tandem mass spectrometry (LC/MS/MS) and a Nuclear magnetic resonance (NMR). The results of this year show the manganese oxide can not effectively oxidize ibuprofen alone but can oxidize ibuprofen with an oxidation assistant, hypochlorite. A lot of products appear after the reaction. The new research for the next two years will be focus on the effects of addition of adsorption assistants, oxidation assistants and energy e on the reaction and determining the products of degradation.
|Effective start/end date||8/1/10 → 7/31/11|
- Acidic pharmaceuticals
- Manganese dioxide