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  The Impact of Chronic Sleep Deprivation on Neurocognition, Mood and Stress Regulation among Adolescents: Observational Follow-Up and Intervention Studies of Healthy Adolescent Cohorts( I )

  Lee, H. & Chiu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Ccr5-Targeted Liposome Encapsulated Immunosuppressive Drug-Tacrolimus for Autoimmune Disease Treatment

  Liu, D.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building the Smart Early Intervention Service

  Tseng, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trajectory and Biomarkers for Post-Stroke Cognitive Impairment( II )

  Hu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Longitudinal Analysis Combining Neuroimage and Proteomic Studies on Fibromyalgia Patients

  Kang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血管性認知功能障礙之精準醫療－腦中風後認知障礙之病程軌跡及生物標記(2/3)(相對補助)

  Hu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › f - Other (Funded by Government)

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響：動物模式與人類世代之整合研究－青少年期慢性睡眠剝奪對認知與情緒功能之影響：動物模式之行為與神經內分泌功能變化探討(1/3)相對補助

  Yang, C. H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › f - Other (Funded by Government)

• Endotoxin Removal Device Based on the Polysulfone(Psf) Microtube Array Membrane (Mtam) with Immobilized Polymyxin B

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Chromatin-Modifying Agents on the Tumor Differentiation and Mibg Uptake of Neuroblastoma

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Cancer and Anti-Inflammatory Properties of Novel Aliphatic Hydroxamate Derivatives: Hdacs- and Mirna-Mediated Post-Transcriptional and Post-Translational Mechanisms

  Hsu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Relevance and Mechanism of Glucose Transporter 3 in Colon Cancer Metastasis: Focus on Tumor Microenvironment and Developing Therapeutics

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploitation of Mesoporous Silica Nanoparticles as Targeted Therapeutics in Cancer Treatment(2/2)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Mechanism of Cd155/Tigit in Mdsc/Tam Induced Nk Cell Dysfunction -A Link to Lung Cancer Resistance to Immune Checkpoint Blockade

  Feng, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers(2/3)

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.( II )

  Huang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Efficacy Assessment and Mechanism Exploration of Kruppel-Like Factor 2-Targeting Intervention Strategy for Non-Small Cell Lung Cancer Therapy(1/3)

  Wu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of 1,3-Diaryl-Substituted Five-Membered Heterocycles as Anti-Pancreatic Cancer Agents(1/3)

  Lee, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Protease-Activated Receptor 4 Antagonists as Novel Antithrombotic Drugs

  Lu, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pharmacological Properties of Novel Natural Naphthoquinone-Based Derivatives: Focusing on Anti-Vegfr and Anti-Tumor Activities

  Huang, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Translational Investigation of the Role of Myc/Pd-L1/Akt Axis as a Therapeutic Target for Treating Glioblastoma Multiforme

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Heat Shock Protein Inhibitors: Pyrimidine as Core Structure for the Use of Organometallic Coupling Reaction in the Synthesis of Series Derivatives

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Synthetic and Medicinal Utility of Organometallics in the Development of Anticancer Epigenetic Inhibitors: Applications and Explorations( I )( I )(1/2)

  Liou, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigations of Adjuvant Drugs in Improving Efficacy of Nk Cell-Based Immunotherapy for Lung Cancer through Comprehensively Transcriptome Profile Analyses

  Shih, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Efficacy of Simvastatin in Renal Cell Carcinoma by Restraining Metabolic Reprogramming from Mtor, Ppar to Rhoa(1/3)

  Juan, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting and Blockades of Advanced and Metastatic Breast Cancer with Trispecific or Dual Bispecific Antibodies Non-Covalently Bound on Mpegylated Nanocarriers Loaded with Docetaxel and Pictilisib for Synergistic Therapy and Circumventing the Resistance

  Sheu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Relationship of Chemical Contents and Pharmacologic Effects between Atractylodes Macrocephala Koidzumi, Its Couplet Medicines and Formulas(2/3)

  Wang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Surface-Enhanced Raman Scattering-Active Substrates Prepared Using Innovative Plasmon-Activated Water(1/3)

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Apoptotic mechanisms in the brain and its relationship to synapse and memory loss(相對補助)

  Chiang, Y.

  8/1/19 → 12/31/20

  Project: A - Government Institution › f - Other (Funded by Government)

• Study the Toxicity of Chitosan Nanowaste in Freshwater Fishes: Establishment of Toxicity Assessment Platform for Nanomaterials

  Cheng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Potential Antitumor Mechanisms of Hyaluronan Synthase Involved in Early Onset Breast Tumor Tissues

  Tu, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fucoidan/Urokinase Assembled Magnetic Nanoparticles for the Detection of Thrombosis and Targeted Thrombolytic Therapy

  Mi, F.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Evaluation and Treatment of Nasal Obstruction in Unilateral Cleft Lip and Palate Patients

  Chen, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Auricle Electroacupuncture Protect Cardiac Function through Potentiating Vagal Tone

  Lin, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Dynamic Change of Genotype and Phenotype in Circulating Tumor Cells and Its Clinical Significance in Cancer Progression

  Lee, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Molecular Mechanisms of Hdac Inhibitors on the Regulation of Calcium Pyrophosphate Crystals Formation

  Chang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Phylogenomics of Carbapenem-Resistant Klebsiella Pneumoniae at a Regional Teaching Hospital in Northern Taiwan

  Huang, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Safety and Quality Assessment of Liquid Eggs Using Portable Spectroscopy Technique

  Chuang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究－探討青少年期慢性睡眠剝奪對壓力調適功能之影響--以腸腦軸線功能變化為例(1/3)相對補助

  Huang, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › f - Other (Funded by Government)

• Phosphodiesterase Isoforms Inhibitors on Atrial Arrhythmogenesis from Modulations on Fibroblasts Activity and Cardiomyocytes Electrophysiology(2/2)

  Huang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Genome-Based Machine Learning Approach for Mining the Functional Potentials of Hypothetical Genes and Predicting Bacterial Antimicrobial-Resistance Phenotypes(1/3)

  Wu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bsp-Like Repeat Family Proteins in Bacterial Immune Evasion and Biofilm Formation in Viridans Streptococci-Induced Infective Endocarditis

  Jung, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Implantable Artificial Kidney Utilizing Nano-Porous Micro Tube Array Membrane Proof of Concept Study

  Wu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of the Protective Effect of Far-Infrared-Improved Mitochondrial Function on Pancreatic Β-Cells in Diabetes Mice and Its Sirt1- and Plzf-Associated Mechanisms(2/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Occurrence and Formation Mechanism of Glycidyl Esters in Edible Oils and Oil-Containing Foods in Taiwan (1/3)

  Lee, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cell Penetrating Peptide Derived from Human Eosinophil Cationic Protein in Allergic Inflammation Modulation- Enhancing Delivery and Effect of Anti-Sense Rna Targeting Stat-6

  Hou, T. & Lee, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Knowledge Translation Research in Evidence-Based Practice Guidelines Methodology Development and Critical Appraisal.

  Chen, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Liver Kinase B1 Dictates Glutamine Addiction and Gemcitabine Response in Pancreatic Ductal Adenocarcinoma

  Chiu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Chlorpyrifos on Polarizing Signals in Cd4+ T Cells during Colitis(2/3)

  Hou, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of Chronic Sleep Deprivation on Stress Adaptation in Adolescent: a Gut-Brain Axis Study( I )

  Huang, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology