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Roles of Autophagy and Heme Oxygenases(-1, -2) in Brain Injuries: in Vivo and in Vitro Studies

Wang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Studies the Function and Mechanism of Dnaja3a/Dnaja3b and Interaction Molecules during the Embryonic Satges

Chow, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

Hsu, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Simultaneous Delivery of an Antisense Oligonucleotide and a Chemotherapeutic Agent by a Her2-Targeted Liposomal System

Chiu, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

包載9α-型尼古丁乙醯膽鹼受體抑制劑之標靶性微脂體劑型設計與開發

Sheu, M.

8/1/127/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

Wu, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

Chen, B. & Chung, C.

8/1/127/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

Translational Genomic Approaches in Endometriosis

Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

8/1/1210/31/13

Project: B - Project of TMUh - Other (Funded by TMU)

Chinese Herbal Compound Extract of Pig Sperm Detection and Activation of the Pharmacokinetic Evaluation and Preparation of R &Amp; D

Lee, C.

8/1/123/31/14

Project: A - Government Institutionb - Ministry of Science and Technology

Renoprotective Mechanisms of Soy Protein in Rats with Diabetic Nephropathy

Chen, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Role of Er Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells

Chen, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury( I )

Chang, W.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

21世紀的公民與風險:全球變遷中的環境,知識和價值

Chiou, H.

8/1/1212/31/13

Project: A - Government Institutiond - Ministry of Education

Lay Health Knowledge Research:Example of Infants and Children Dietary Supplement

Chen, Y. C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Biological Mechanisms of N-3 Polyunsaturated Fatty Acid Treatment in Interferon-Induced Depression

Huang, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Adlay Hull Extracts on Polycystic Ovary Syndrome (Pcos)

Hsia, S.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Community-Based Screening and Prevention Model for Periodontal Disease

Chen, L.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Design and Evaluation of a Novel Drug-Containing Ceramic Hydrogel for the Healing of Alveolar Bone Defect

Lee, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Genomic Approaches in Endometriosis

Tzeng, C.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Oxidative Stress and Bisphenol a Impact on the Women with Polycystic Ovary Syndrome

Hsu, M.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Motorcyclist Behavioural Patterns to Pedestrian Green Signal Countdown Device (Pgscd): a Mixed Logit Analysis

Pai, C.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Chemokine Factors Concomitantly Induce Prostate Cancer Organ Specific Bone Metastasis

Sung, S.

8/1/129/30/13

Project: A - Government Institutionb - Ministry of Science and Technology

Bullying Experience, Attitude and Suicide Attempts among Adolescents

Chen, P.

8/1/127/31/14

Project: A - Government Institutionb - Ministry of Science and Technology

探究腦指蛋白 ZNF179 (Brain Finger Protein) 的分子機制

Huang, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Study the Klf10 Alters Metabolic Pathways in Genetic-Deficient Mice and Human Pancreatic Ductal Carcinomas

Chang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Advanced Research for a Decision Model of Emergency Patient Intelligent Dispatch

Hsu, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

依療法律與醫學倫理

Ho, J.

8/1/121/31/13

Project: A - Government Institutiond - Ministry of Education

The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

Lin, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

Peng, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Enhancement of Immuno-Modulatory Capacity by Shear Stress in Mesenchymal Stem Cells

Ho, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

Lin, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Novel Development of Continuous Bladder Volume Measurement System

Chen, S.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

The Effects of Music Therapy on Psychological Distress and Functional Recovery in Patients with Stroke

Chang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

Kang, J.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Oral Health and Interventions for Elderly in Long-Term Care Facilities

Chang, C.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

Chen, T.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生,形成症狀群集,影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨,然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解,仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗,將有助於未來睡眠評估工具之修訂。另外, 在評估癌症病人睡眠品質時,若能以簡單工具評估,會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷,廣為使用在一般失眠的病人, 在癌症病人使用上,尚未有豐富的實證資料,若能建立其在癌症病人的信效度,將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則,日夜節律又需要光作為矯正的線索,光在癌症病人睡眠的 角色,尚未有研究證實,過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索,光療法透過褪黑激素調節,調整日夜節律週期,可能可以改善睡 眠品質。另外,由於,睡眠障礙、憂鬱、疲憊經常形成一症狀群集,光療法於改善睡眠 障礙之同時,是否亦同時改善憂鬱、疲憊及生活品質。目前,光療法在癌症病人的運用 上,付之闕如,故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫,目的包括有:1.瞭解癌症個案對於睡眠困擾的主觀經驗 (第一年)。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性(第一年)。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係(第二年)。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效;以及瞭解光療法影響褪黑激素之 程度(第三年)。 本研究擬以癌症住院及門診病人為對象,研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷,簡明疲憊量表,貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括:內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係,並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效,以期,最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

Lin, C.

8/1/1210/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

Chang, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

Chen, Y.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Targeting Hif-1α by Zebularine for the Treatment of Colorectal Cancers

Yang, P.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Improvement of Cryopreservative Effect of Natural Killer Cell by Increasing Membrane Rigidity Using Static Magnetic Field

Huang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology

Effects of Childhood Sleep Deprivation on the Development of Emotional Control and Cognitive Function of Prefrontal Cortex

Chang, H.

8/1/127/31/13

Project: A - Government Institutionb - Ministry of Science and Technology