Find Research Projects

Search results

• Finished

  以參功能抗體或雙功能抗體非共價鍵合至負載 Docetaxel 與 Pictilisib 協同組合量比之聚乙二醇化奈米載體而賦予雙標靶與阻斷功效以用於惡性與轉移性乳癌治療之療效加乘與規避耐藥性(3/3)

  Sheu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 台灣肝硬化病人使用抗膽鹼藥物與發生肝性腦病變之風險評估(1/3)

  Wu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Role of Attentional Amplification in Subliminal Auditory Processing in Patients with Schziphrenia: a Behavioral, EEG, Pupillometry, and Mrs Study

  Lin, I.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Schizophrenia 100%
  • Subliminal Stimulation 44%
  • Behavioral Symptoms 29%
  • Auditory Cortex 28%
  • Pupil 26%

• 3D實境對於達文西手術教學平台建立與操作能力提升(2/2)

  Liu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用長期血液循環腫瘤DNA探討基因變異與前列腺癌復發風險與抗藥性以發展個人化醫療標記之研究

  Shao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 基於深度學習與機器學習混合分析多體學數據於癌症精準醫學治療之應用評估(1/2)

  Chang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 智能人類血小板顆粒結合多功能聚合物載體做為新型治療的生物醫學平台(2/3)

  Chuang, E.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用蛋白質補充劑於慢性中風患者之復健訓練

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 整合臨床血液透析高分辨率生物活體脈衝光驅動鹵素鈣鈦礦成像於微觀血管彈性研究與紅外線照射系統

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嗜伊紅性白血球陽離子蛋白衍生之細胞穿透胜肽對於調節過敏性發炎之研究- 促進STAT-6反義RNA之運送與表現(2/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化酶調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(1/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• P-選擇素調控具靶向多功能陰離子奈米載體包覆雙嘧達莫或白蛋白具有遠紅外光可觸發的熱療溫度/藥物釋放的聯合療法做為臨床應用(2/3)

  Chuang, E.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 胃腸科相關癌症之差異蛋白質體與致病機轉之研究

  Lee, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞模式探討軟組織肉瘤的藥物治療策略(2/2)

  Lu, L.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用藥物基因體發展急性登革熱病毒感染期間免疫反應之臨床診斷：探討T細胞組庫和C-型凝集素基因家族之遺傳變異(1/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發1,3-二芳基取代之五元雜環作為抗胰臟癌劑(2/3)

  Lee, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫三：運用跨模態多項次神經影像技術探討神經調控模式對脊髓損傷者之神經可塑性與功能變化(2/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 3D間葉幹細胞球體培養之血管和成骨分化潛能評估(2/3)

  Feng, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以尿苷雙磷酸葡萄糖醛酸基轉移酶2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(1/3)

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-建立原發性和再復發膠質母細胞瘤免疫圖譜以及建立免疫療法(2/3)

  Lee, G.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• anti-EGFR×anti-FAP雙辨識特異性抗體結合包覆抗癌藥物Irinotecan標靶微脂體治療胰臟癌之研究(3/3)

  Lin, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(1/2)

  Wang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者視網膜血管和頸動脈粥狀化、視神經層厚度和腦體積之關聯及影響因素

  Tsai, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(1/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討脯氨酸循環調控癌細胞代謝重組與腸道菌群在胰腺癌吉西他濱抗藥性中的作用

  Huang, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以腸-肝-肌肉軸觀點探討腸道健康促進因子對於酒精性肝臟疾病大鼠腸漏症、腸道菌相多樣性及肌少症的影響(3/3)

  Yang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探查Pearson氏症候群的基因診斷與在患者衍生細胞上的施行清除粒線體DNA缺失的可行性

  Kao, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明Hiltonol為主的複合式用藥在肺癌生長，轉移和腫瘤微環境中的作用。

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合神經影像及蛋白質體學的纖維肌痛症者的縱向分析(2/2)

  Kang, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(1/3)

  Chuang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發透明質酸基奈米藥物以增強後眼部藥物遞送效能及應用於藍光誘導損傷之視網膜病變治療

  Tseng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(1/3)

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第五型驅化物在糖尿病影響中風後所導致的血管性失智症中扮演的角色-(2)

  Chou, S.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制site-1蛋白酶引發肝癌細胞自我吞噬之研究

  Yang, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bilateral Parietal-Prefrontal and Glutamatergic Activity in Schizophrenia Patients--Fmri, Rsmri, and Mrs Investigation

  Lane, T. J., Lin, I., Tseng, P. & Lu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Schizophrenia 100%
  • Clinical Trial Protocols 93%
  • Glutamic Acid 53%
  • Electroencephalography 52%
  • Magnetic Resonance Imaging 40%

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(2/3)

  Lee, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討以Myc/PD-L1/Akt作為治療惡性腦癌標靶之轉譯研究(3/3)

  Lin, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發具有骨誘導性之溫感性水膠包埋凍乾型富含血小板纖維蛋白並結合人工代用骨複合型材料用於兔子臨界骨缺損之修補(1/3)

  Wong, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對癌症治療研發與活性最適化蛋白質激酶抑制劑(2/3)

  Hsu, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 探討運用翻轉教室與辯論式教學對護理倫理與法律概論課程之學習成效

  Tsai, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › d - Ministry of Education

• Analyzing the Effectiveness and Portfolios of an Wsq Guiding Strategy-Based Flipped Learning in Maternity Nursing Courses

  Chang, C.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構及評值『舌強化運動與謝克式運動』於輕度認知功能障礙衰弱老人之吞嚥功能、舌肌力、誤吸、營養不良風險及吞嚥生活品質成效之探討：一臨床試驗研究(1/3)

  Chou, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 糖尿病老人之肌少症盛行率、相關因素及健康促進方案研究(2/2)

  Lee, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 強化藍光之白光光照法改善纖維肌痛症患者睡眠、憂鬱、神經運動警覺度及症狀嚴重度之成效(1/3)

  Tsai, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討以網絡平台及個人化為基礎的認知行為治療方案 (Deprexis) 在台灣憂鬱症個案的成效: 隨機對照試驗(1/3)

  Chang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不孕症婦女心理困擾變化軌跡：身心療癒措施結合心率變異生理回饋之成效與機轉(3/3)

  Kuo, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Tactile?massage改善長照機構老年住民孤寂、焦慮及憂鬱之成效探討

  Chuang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肝硬化肌少症：篩檢方法驗證與運動、飲食補充介入成效評估(2/2)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology