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• b - Ministry of Science and Technology

  Insights into the Molecular Mechanisms of Lithium on Cardioprotection in Social Stress(2/2)

  Chen, P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Extracellular Matrix Collagens-Driven Acidic Microenvironment Confers Malignant Properties in Bladder Tumors (2/2)

  Lee, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Combination of E1A Gene Therapy and EGFR Tyrosine Kinase Inhibitors in TNBC---Preclinical Studies May Light up the New Therapeutic Strategy

  Su, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 全球傳染病防治中的政策成效與影響因素研究--以國際衛生條例與大流感防治框架為核心(3/3)

  Tsai, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Successful Aging through Afternoon Napping and Meditation: Unveiling Underlying Brain Mechanisms through Cerebrovascular Reactivity and Brain Integrations

  Wu, C. W.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討高尿酸血症(痛風)病人與日後罹患阿茲海默症疾病風險的相關性研究

  Yang, W.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發雷射複合3D列印高通量微陣列結構技術穿戴式晶片於汗液檢測糖尿病診斷之應用(2/2)

  Chen, Z.

  10/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Physiological Indicators of Early Cardiac Dysfunction in Patients with Schizophrenia

  Chen, P.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cultivation‭ ‬Of Mindfulness‭ ‬Via‭ ‬The‭ ‬Intelligent Neurofeedback‭ ‬And‭ ‬Disciplinary‭ ‬ Vi Rtual Reality‭ (‬Mindvr‭)‬‭ ‬Platform‭ ‬On Middle-Aged and Elderly Population

  Wu, C. W.

  6/1/19 → 5/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Primary and Distal Metastatic Microenvironments through Ddr1 Affect Therapeutic Strategy of Bladder Cancer(1/2)

  Lee, Y.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜異位症體外血清診斷試劑開發計畫(1/2)

  Yang, W.

  8/1/15 → 3/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討原位及遠端轉移腫瘤微環境藉由酪氨酸激酶接受器DDR1影響膀胱癌的治療策略(2/2)

  Lee, Y.

  1/1/21 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Differential Effects and the Mechanisms of Flavonols on Osteogenic Differentiation of Human Dental Pulp Stem Cells

  Lee, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作計畫-利用智慧型穿載設備發展癌因性疲憊之精準健康照護系統

  Huang, T.

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?

  Peng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The relationship and predictors of electrocardiography, inflammatory markers, clinical features in older bipolar and schizophrenia patients concurrent with coronary heart and cerebro-vascular diseases

  Tsai, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establish the General Rules of Concomitant Administration of Xiang-Sha-Liu-Jun-Zi-Tang and Its Compatibility with Western Drugs on Cyp Enzymes in Vitro and in Vivo (1/3)

  Lee, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Precise Health Care for Carcinogenic Oral Mucositis: a Randomized Clinical Trial Using Bee Products

  Huang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Quantifying Fatigue in Cancer Patients Using Smart Bracelet Devices

  Huang, T.

  11/1/19 → 10/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?(3/3)

  Peng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 使用Brush Monster APP製作口腔衛教方案於癌症相關口腔炎之成效

  Huang, T.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Alteration of Inflammatory Reflex and Its Association with Psychotropic Drugs in Bipolar Disorder from Acute Mania to Full Remission

  Tsai, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development and Characterization of Zein-Sodium Caseinate Nanoparticles-Hydrogel Composite for Localized and Sustained Sirna Delivery(3/3)

  Hsieh, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The New Therapeutic Tactic of 2, 3, 5, 4’ Tetrahydroxystilbene-2-O-Β-D-Glucoside on Human Dental Pulp Stem Cells Oriented Tissue Regeneration(1/2)

  Lee, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構定量系統生理基礎藥動模型以評估腸道菌叢對口服藥物代謝影響及協助奈米膠體處方之開發(1/3)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高分子混合微胞結合溫度敏感型水膠之雙效釋放劑型開發與應用

  Hsieh, C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Estrogen Receptor Regulates Stemness Properties of Endometrial Stem Cells and Its Clinical Significance in Endometriosis.

  Au, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 應用二苯乙烯苷刺激人類牙髓幹細胞衍生的外泌體於再生醫學之臨床前研究(1/3)

  Lee, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討張口受限患者的牙關緊閉與生活品質之關係

  Huang, T.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Applying Addie Model in Developing Educational Program about Depressive Symptoms among Older Residents for Nurses in Long-Term Care Facilities

  Chuang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Applying ADDIE Model in Developing Educational Program about Depressive Symptoms among Older Residents for Nurses in Long-Term Care Facilities(2/3)

  Chuang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Alteration of Inflammatory Reflex and Its Association with Psychotropic Drugs in Bipolar Disorder from Acute Mania to Full Remission(2/2)

  Tsai, S.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the bacteria species of pneumonia and early detect the pathogen from expired gas by electronic nose

  Shih, C.

  5/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Amelioration of Non-Alcoholic Fatty Liver Diseases by Gaba-Enriched Koji and the Mechanisms Based on the Liver-Gut Axis

  Yang, S.

  6/1/22 → 5/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腸道功能保護因子麩醯胺與慢性酒精攝取大鼠肌肉胺基酸組成之相關性

  Yang, S.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation

  Hou, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trajectories, Predictors of Return-to-Work, and the Impact of Return-to-Work in Predicting the Quality-of-Life among Workers with Traumatic Limb Injuries

  Hou, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血管內皮β-catenin活化於動靜脈廔管狹窄之角色

  Sue, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development, Implementation, Evaluation, and Promotion the Interprofessional Shared Decision Making in Holistic Care: Innovating a Blended Learning Environment with Artificial Intelligence (1/3)

  Hou, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗發炎藥物與生物製劑藥物對類風濕性關節炎病人發生惡性腫瘤之影響：健保資料庫分析研究

  Chen, S. H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(2/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以卷積神經網路、類神經網路、支持向量機、隨機森林及羅吉斯迴歸五者探勘技術預測肺癌病人鉑類藥物之腎毒性不良反應

  Chen, S. H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Host Factors Affecting the Pathogenesis of Enterovirus 71 in Neuron and Non-Returnable Cells

  Lin, J.

  12/1/13 → 11/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Construction and Application of Spatio-Temporal Database and Geography Information System for Emergency Medical Care( III )

  Lin, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effectiveness of Implementing Shared Decision-Making on Quality of Care among Patients with Lumbar Degenerative Diseases: a Cluster Randomized Controlled Trail(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Health Service Utilization and Costs among Patients with Schizophrenia Receiving Long-Acting Injectable Risperidone and Medical-Decision Making in Prescribing Long -Acting Injectable Antipsychotics by Psychiatrists

  Huang, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Anti-Cancer Activity of Folic Acid

  Lee, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology