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• b - Ministry of Science and Technology

  Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Kdm4a in Prostate Cancer(III)(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(2/3)

  Liu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Three Steps of Fluorescence Resonance Energy Transfer Observation of Complexation of DNA/Drug/Polymeric Micelles on Cornea Transport

  Liaw, J.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Micelle 100%
  • Fluorescence Resonance Energy Transfer 69%
  • Fluorescence 18%
  • Antiapoptotic 18%
  • Donor 13%

• 探討短鏈脂肪酸抑制造成過敏作用之免疫細胞的調控機制及其對過敏性氣喘疾病之治療特性評估(3/3)

  Lee, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 29%
  • Mast Cells 27%
  • Immunoglobulin E 20%
  • Asthma 17%

• Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( II )

  Huang, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Pathogenesis of Progression of Cerebral toxocariasis into Alzheimer’s-Like Disease Affected by Dysfunctional Regulation from Impaired UPS and ALS That Lead to Aberrant Βeta-Amyloid Generation and Metabolism in Brain

  Fan, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 75%
  • Proteasome Endopeptidase Complex 60%
  • Ubiquitin 51%
  • Amyloid Precursor Protein Secretases 45%

• Outcomes research in gout: economic impact, humanistic burden, and pharmacoeconomic evaluation

  Ko, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identifying Cancer-Stem-Cell-Invadopodia-Related Prognostic Biomarkers in Gastric Cancer

  Chan, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Podosomes 100%
  • Neoplastic Stem Cells 71%
  • Stomach Neoplasms 27%
  • Neoplasms 18%
  • Neoplasm Metastasis 11%

• https://www.grb.gov.tw/search/planDetail?id=8356932&docId=447412

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Synovial Fluid 29%
  • Proteins 28%
  • Autoantibodies 17%
  • Rheumatoid Arthritis 15%

• Depression Trajectories in Women – a Developmental-Ecological Approach (Gm03)

  Kuo, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Depression 100%
  • Cohort Studies 34%
  • Postpartum Period 24%
  • Longitudinal Studies 21%
  • Retrospective Studies 17%

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(2/3)

  Chao, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討大葉樹蘭萃取物Rocaglamide A 對三陰性乳癌的影響及其作用機制

  Huang, T.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• ALA Photodynamic Therapy, Tumor Hypoxia, CSE1L Phosphorylation, and the Progression and Treatment of Skin Cancer

  Lee, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Aminolevulinic Acid 31%
  • Tumor Hypoxia 25%
  • Neoplasms 24%
  • Photochemotherapy 20%

• A High Density and Nano-Sized ReRAM Crossbar Array Using Copper Chemical Displacement and Nanotip Array Techniques (I)

  Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • random access memory 100%
  • diodes 21%
  • copper 13%
  • schedules 11%
  • nitrides 8%

• Roles of Microrna96 in Tgfβ-Mediated Tumor Progression

  Tsai, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transforming Growth Factors 100%
  • Neoplasms 26%
  • Prostatic Neoplasms 21%
  • Castration 15%
  • Androgen Receptors 14%

• Occupation Choices, Work Characteristics, and Career Success of Medical Technology Undergraduates from Gender and Generational Perspectives (K01)

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medical technology 100%
  • bachelor 44%
  • graduate 29%
  • gender role 22%
  • Taiwan 19%

• Using Computer-Aided Drug Design and Optimization of Lead Compound to Develop Drug Candidate for Treatment of Breast Cancer

  Lin, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Type II DNA Topoisomerase 100%
  • Carrier Proteins 59%
  • Triple Negative Breast Neoplasms 42%
  • Chromones 23%
  • Drug Design 16%

• Is proton pump inhibitor a risk factor to bacterial gastroenteritis: A meta-analysis

  Bai, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Gold Nanoparticle-Modified Electrode of Electrochemical Sensor for Rheumatoid Arthritis Diagnosis

  Fan, Y.

  6/1/19 → 5/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Laser Enhancement of Transdermal Delivery of Nanoparticles

  Lee, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • delivery 100%
  • antibiotics 82%
  • strata 76%
  • drugs 75%
  • lasers 71%

• Role of Progesterone Receptor on the Folic Acid-Induced Anti-Tumor Growth and Metastasis(2/3)

  Lee, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metronomic Chemotherapy Potentiates Immuno-Surveillance and Immunotherapy in Desmoplastic Pancreatic Cancer: Focusing on the Roles of Tumor Stroma and Myeloid-Derived Suppressor Cells( I )(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Could Bicalutamide–Induced Renal Fibrosis Take the Pathway Tgf-B1/Wnt That Further Triggers Mesangial Mitochondrial Dysfunction and Metabolic Reprogramming? - Evaluation of Prognosis on Cotherapy of Nac, Nad+, Riboflavin, and Coq?

  Peng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Diagnostic and Prognostic Biomarker for Acute Stroke in Serum Translocator Protein (Tspo) and the Related Association with Neuro-Inflammation

  Bai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Blood Proteins 27%
  • Biomarkers 15%
  • Proteins 14%
  • Creatinine 12%

• Storied Residence and Restorative Justice: a Study on the Foodscapes and Eco-Spirituality of Tayal’S B’Bu Area

  Lin, Y.

  1/1/17 → 12/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • spirituality 100%
  • ethnic group 50%
  • justice 45%
  • ecological system 39%
  • discourse analysis 28%

• 開發蛋白質雙硫鍵異構酶抑制劑作為抗多形性神經膠質母細胞瘤藥物

  Huang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Pcl/Β-Tcp Composite in Bony Defect Application

  Chang, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Impacts of Histone Methylation Dynamics on Colorectal Cancer Progression and Immunotherapy Responsiveness( II )

  Liao, T.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Reduction of Chemotherapy Side Effects Using the Tonify Spleen and Fortify the Stomach Formulas Complementary Treatment

  Wang, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Reduction 51%
  • Pharmacokinetics 42%
  • Paclitaxel 34%
  • Mining 32%

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• Studies of Roles of SIRT7 in Cancer Biology

  Tsai, Y.

  1/1/14 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • neoplasm cells 59%
  • Biological Sciences 47%
  • cancer therapy 31%
  • drug development 27%

• Investigation of Endoplasmic Reticulum Stress Response and Autophagy in Chronic Kidney Disease by Nanoparticle Drug Delivery System

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting and Blockades of Advanced and Metastatic Breast Cancer with Trispecific or Dual Bispecific Antibodies Non-Covalently Bound on Mpegylated Nanocarriers Loaded with Docetaxel and Pictilisib for Synergistic Therapy and Circumventing the Resistance(1/3)

  Sheu, M.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline

  Bai, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Metabolic Syndrome 67%
  • Mental Status and Dementia Tests 50%
  • Thromboplastin 27%
  • Waist Circumference 24%

• Molecular Epidemiology of Urothelial Carcinoma Prognosis Based on Microrna Expression Profiles

  Wang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Carcinoma 87%
  • Biomarkers 34%
  • Neoplasms 34%
  • Arsenic 31%

• Investigating the Role of Btk/Her2 Signaling as a Therapeutic Target for Restoration of T Cell Function and Reversal of Trastuzumab Resistance in Her2+ Breast Cancer(1/3)

  Chao, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Pathogenesis of Cerebral Neuroglia Cells on Tjps and Biabs Expressions as Well as Ups Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 74%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Disasters, Migration and Landscapes of Spirituality: a Case Study on the Post-Morokot Reconstruction with the Lai-Ji Village of the Tsou Tribe

  Lin, Y.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • spirituality 100%
  • village 94%
  • reconstruction 67%
  • natural disaster 53%
  • ethnic group 45%

• 研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(1/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cisplatin 100%
  • Kidney 45%
  • Knockout Mice 31%
  • Renal Insufficiency 22%
  • Wounds and Injuries 16%

• The Role of Cytoplasmic APe1 in Tumor Malignancy, Drug Resistance and Lung Cancer Prognosis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • NF-kappa B 100%
  • Oxidation-Reduction 45%
  • Cell Nucleus Active Transport 44%
  • Lung Neoplasms 37%
  • Neoplasms 36%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• The Clinical Effects of Deep Oscillation Massage in Treating Fibromyalgia

  Kang, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Massage 46%
  • Vibration 42%
  • Therapeutics 13%
  • Pain 13%

• 探究LINC01540/miR-107調控軸於口腔癌惡化進程之功能及其臨床意涵

  Tsai, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the mechanism of HPV involved tumorigenesis through Wnt signaling pathway related microRNA regulation

  Cheng, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • beta Catenin 90%
  • Lung Neoplasms 58%
  • Carcinogenesis 56%
  • Lung 55%

• A Polycrystalline Silicon Nanowire Field Effect Transistor Biosensor Using Lateral Oxidation of Silicon Technique and Its Improvement on Sensitivity

  Wu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-H and Plc-Delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Drug Resistance 40%
  • Proteins 28%
  • Peptide Fragments 19%
  • Neoplasm Metastasis 18%