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• 利用生物晶片探討中草藥於神經保護活性中之所扮演的角色

  Lee, M.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 薑黃素衍生物的抗癌癌細胞轉移活性研究

  Hou, W.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 研發可抑制腸內菌葡萄糖酸??之中草藥萃取物以提升癌症化療之功效

  Chuang, K.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 第四型類鐸接受器在大腸直腸癌化學治療效果上的角色及其作用機制探討

  Huang, M.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討以植物化學成分抑制β-catenin/PIN1訊息傳道路徑於肝癌幹細胞的發生

  Wu, T. A.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 應母親請求剖腹產和陰道生產出生的新生兒其出生後的生理適應性

  Chen, C.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• (101NP1003) New Drug Development of MPT0E014 for Ischemic Stroke and Dementia (I)

  Hung, K.

  5/1/12 → 4/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • Stroke 25%
  • Dementia 20%
  • Chromatin 13%
  • Acetylation 9%

• 以PRP高濃度血小板血漿促進前十字韌帶重建手術加強痊癒之研究

  Lee, C.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討眼窩脂肪幹細胞對巨噬細胞活性之影響及其相關調控機制

  Ho, J.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 淋巴管內皮細胞粒腺體導致細胞死亡的關鍵角色探討

  Sheu, J.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討北縣市國小及國中學生鐵營養值標與肥胖及新陳代謝症候群的關聯

  Chang, J.

  5/1/12 → 10/31/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討Zc3h12a及Zc3hav1L在結腸直腸癌生長上所扮演的角色

  Liang, Y.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  5/1/12 → 4/30/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• 薑黃素衍生物的抗發炎活性分析與機制探討

  Liang, Y.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Heme oxygenase-1在促進TPA誘導大腸腺癌細胞轉移與活化cyclooxygenase-2之角色

  Chen, Y.

  5/1/12 → 4/30/14

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 整合醫院資訊系統、數據收集和資訊代表性技術的挑戰

  Li, Y.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 利用電漿表面改質促進鈦植體表面生物相容性之研究

  Peng, P.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 以彈性工程提升加護病房病人安全之應用研究

  Chuang, S.

  5/1/12 → 10/31/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 脂多醣體引起淋巴內皮細胞死亡(細胞凋亡，自體吞噬及細胞壞死)之訊息傳遞作用

  Chang, N.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Hesperidin-3’-O-methylether在天竺鼠組織抑制3H-rolipram於high-affinity rolipram binding sites之結合及phosphodiesterase isozymes 1~5之活性

  Ko, W.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Study the mechanisms of endogenous free radical formation in acquired lymphedemic mice

  Chang, N.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Study the bacteria species of pneumonia and early detect the pathogen from expired gas by electronic nose

  Shih, C.

  5/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 遠紅外線治療在血管平滑肌細胞中對腎素訊號傳遞之影響

  Hsu, Y.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 神經細胞中過氧化物?體增殖物活化受體-γ在高血糖及缺氧環境下的表現及對神經細胞存活能力的研究

  Chi, N.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 以MALDI與TOF-SIMS研究大腸癌組織Heme oxygenase-1與腫瘤相關蛋白及鐵離子表現變化

  Chang, J.

  5/1/12 → 4/30/14

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 以超靈敏奈米線感測器偵測口腔癌症指標

  Wu, C.

  5/1/12 → 5/31/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 子宮病變與環境荷爾蒙之關係研究

  Lee, C.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• c-Src/NADPH oxidase/ROS訊息路徑參與表皮生長因子誘導人類大腸癌細胞heme oxygenase-1表現之研究

  Chen, B.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 巴金森氏病之嗅覺腦波頻譜分析及嗅覺誘發電位研究

  Chiu, H.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Feasibility of Capitation for the Accountable Family Physician System: An Exploratory Study

  Sheu, M., Hsu, Y. & Wen, H.

  5/2/12 → 3/31/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • health insurance 100%
  • family physician 61%
  • stakeholder 22%
  • fee-for-service 21%
  • Health Care Providers 17%

• Research Symposium for Chinese Medicine Research Projects

  Liang, W., Huang, W. & Lin, M.

  6/1/12 → 12/15/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • medicine 100%
  • research results 51%
  • academic exchange 41%
  • poster 29%
  • budget 22%

• Study of solid cultivated fruit bodies of Antrodia camphorata combined with or without aspirin on neuroprotection and lowering the neurobehavioral deficits in rat ischemic stroke: evaluating the risks of inducing hemorrhagic side effects.

  Sheu, J.

  6/1/12 → 12/31/12

  Project: A - Government Institution › e - Council of Agriculture

  • Antrodia 100%
  • Stroke 44%
  • Aspirin 29%
  • Cardiovascular Diseases 18%
  • Dietary Supplements 13%

• 101年度建置健保法學知識數位平台

  Yang, C.

  6/29/12 → 12/28/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • health insurance 100%
  • electronic learning 24%
  • death and dying 12%
  • needs assessment 10%
  • health care workers 8%

• 以混合羅吉特模型分析機車路口使用兩段式左轉之行為

  Pai, C.

  7/5/12 → 9/3/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 護理碩士進階實務人才培育共識論壇

  Lin, C.

  7/6/12 → 7/27/12

  Project: A - Government Institution › d - Ministry of Education

• The studies and analysis of the addiction,abuse and social risk of emerging abused drugs

  Sheu, S.

  7/10/12 → 12/31/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Pharmacopoeias 100%
  • Names 98%
  • Pharmaceutical Preparations 75%
  • Pharmaceutical Databases 73%
  • 2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one 63%

• 探討加護病房多種致病微生物揮發性有機成分

  Shih, C.

  7/25/12 → 11/30/12

  Project: A - Government Institution › f - Other (Funded by Government)

• The Roles of Genetic Polymorphisms for Susceptibility and Clinical Outcomes of Colorectal Cancer in Taiwanese Lynch Syndrome Families

  Yeh, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hereditary Nonpolyposis Colorectal Neoplasms 100%
  • DNA Mismatch Repair 90%
  • Colorectal Neoplasms 54%
  • Mutation 30%
  • Genetic Polymorphisms 29%

• Community-Based Screening and Prevention Model for Periodontal Disease

  Chen, L.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Periodontal Diseases 100%
  • American Dental Association 13%
  • History 12%
  • Tooth Loss 10%
  • Taiwan 8%

• Preceptors’ Perceptions of Training Programs and Training Needs, Experienced Barriers during Precepting, and Development and Effectiveness Evaluation of a Preceptor Intervention

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • training program 100%
  • patient care 87%
  • nurse 64%
  • questionnaire 63%
  • interview 53%

• Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exercise 100%
  • Lung Neoplasms 77%
  • Elderly 66%
  • Cancer Survivors 61%
  • Anxiety 60%

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 34%
  • Neoplasms 25%
  • Sleep Initiation and Maintenance Disorders 22%
  • Light 15%

• The Role of Hypoxia in Transcriptomics and Epigenomics Regulation during Pre-Implantation Embryo Development

  Tzeng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hypoxia 100%
  • embryogenesis 74%
  • epigenetics 57%
  • microRNA 22%
  • embryo implantation 18%

• Avoidable Hospitalizations and Primary Care Manpower in a Universal Health Insurance System: a 15-Year Trend Analysis

  Huang, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hospitalization 100%
  • health insurance 46%
  • Taiwan 44%
  • trend 29%
  • manpower 24%

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood-Brain Barrier 100%
  • Propofol 73%
  • Hypoxia 36%
  • Brain Edema 25%
  • Craniocerebral Trauma 22%

• 探討鎮靜藥物dexmedetomidine保護腦血管免於缺血-再灌流傷害之機轉: 細胞和動物研究

  Wu, G.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Oxidative Stress and Bisphenol a Impact on the Women with Polycystic Ovary Syndrome

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • oxidative stress 100%
  • woman 65%
  • reactive oxygen species 61%
  • disturbance 47%
  • gamete 45%

• Detrimental Effects of an Aryl-Hydrocarbon Receptor Agonist, 3mc, on Brain Vascular Integrity and Permeability, and the Therapeutic Intervention by Statin Derivatives.

  Juan, S.

  8/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Retinoblastoma Protein 56%
  • extracellular matrix receptor 50%
  • Extracellular Matrix Proteins 49%
  • Phosphatidylinositol 3-Kinases 33%

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells.

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • atrophy 100%
  • myogenic regulatory factors 41%
  • stem cells 38%
  • muscular atrophy 37%
  • adipocytes 27%

• Exploring the Regulatory Mechanisms of Ep2-Mediated Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma

  Kuo, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epithelial-Mesenchymal Transition 100%
  • Phosphatidylinositol 3-Kinases 79%
  • Esophageal Neoplasms 49%
  • Cell Movement 39%
  • Snails 39%