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• 探討慢性阻塞性肺病受類Toll受體活化調控長鏈非編碼核醣核酸的角色(3/3)

  Wu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以標靶MEG3/miR-181a/Egr1調控軸為標的探討褐藻醣膠防治口腔黏膜下纖維化症之分子機制及轉譯應用(1/2)

  Fang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養甜味劑暴露之評估及其對脂肪組織的影響(2/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性USP24抑制劑於膠質母細胞瘤抗藥性之機轉探討

  Wang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(2/3)

  Tu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長期高脂飲食誘發之腸道菌相改變、食物與脂肪代謝產物、與肝臟及腦部功能退化之相關性

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TAMs/CXCL6/CXCLR2腫瘤免疫交聯軸促進肝細胞癌之放射線治療抗性的機制研究

  Tsai, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Telekaryophagy，一種在肝臟和乳腺中新發現的全核消除程序：探索其在基因組穩定性和生理病理學中的作用(1/3)

  Chao, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧微環境腫瘤外泌體與發炎細胞激素IL-6於B型肝炎病毒誘導肝癌表現多能性幹細胞基因OCT4與TKI抗藥性之調控機制與其臨床意義

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討缺氧誘導之 lncRNA MIR210HG 在腦瘤惡性進程及促進 temozolomide 藥物抗藥性機轉中角色，並評估其作為腦瘤治療標的之可行性

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立脊椎骨小樑之多切面電腦斷層掃描參考值及預測脆性骨折風險(1/3)

  Chan, W. P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 標靶整合素αvβ3-FAK訊號網絡的膽管癌診療策略開發-基於整合素αvβ3和CEACAM6的訊號網絡建立膽管癌患者的診斷生物標記與治療標靶之臨床連結(1/3)

  Whang-Peng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以循環腫瘤細胞擴增系統預測非小細胞肺癌治療反應

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of ARCS model of motivation and experiential learning theory in Gerontological Nursing course

  Chuang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 探討牙周病對牛皮癬之影響與治療用藥策略性之研究

  Lee, A.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Establishment, Effectiveness Evaluation and Learning Behavior Analysis of Contextual-Based Maternal Learning Environment Based on Knowledge-Based Expert System

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 遠紅外線改善骨骼肌和白色脂肪細胞胰島素阻抗的作用及其PLZF相關機制的研究(1/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以代謝工程建立紫色桿菌素胞外生產系統與其連續式醱酵製程開發(1/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發具有骨誘導性之溫感性水膠包埋凍乾型富含血小板纖維蛋白並結合人工代用骨複合型材料用於兔子臨界骨缺損之修補(2/3)

  Wong, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 癌症代謝重整對肥胖相關乳癌之分子調控與轉譯價值

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用機器學習演算法透過基因體資訊挖掘未知基因的功能與預測細菌抗藥性(3/3)

  Wu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Tactile Massage in Improving Older Residents' Psychological Health and Related Indicators in Long-Term Care Facilities

  Chuang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 具機械強度、可降解及骨誘導能力之鎂基非晶質合金應用於高位脛骨截骨矯正術之骨填充楔開發(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以智慧輔助科技介入失智症照護及其社會經濟影響－以智慧輔助科技介 入失智症照護及其社會經濟影響

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 間質幹細胞在低氧微環境促進神經內分泌型前列腺癌的作用與新穎治療策略(1/3)

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性DYRK1A抑制劑於阿茲海默症之機轉探討(3/3)

  HuangFu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 脂質薑黃素顆粒(SLCP)在體內對mTOR訊息路徑的作用–尋求以疾病機制為基礎對結節性硬化症(TSC)癲癇的治療策略(1/3)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 副甲狀腺素藉由SFRP2導致動靜脈廔管病變之惡化 – 預防動靜脈廔管不成熟之新治療標的 (第二年延續計畫)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Efficacy of “Tongue Strengthening Exercise and Shaker Exercise” on Swallowing Function, Tongue Strength, Aspiration, Risk of Malnutrition and Swallowing Quality of Life for Frail Elders with Mild Cognitive Impairment: a Randomized Controlled Study (2/3)

  Chou, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討急性肺損傷之精準幹細胞治療策略與臨床應用: 肺部微環境修復之分子與細胞圖譜及其作用機制-臨床級胎盤間葉幹細胞對急性肺損傷/急性呼吸窘迫症之免疫調控與肺組織再生之治療機制(1/3)

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• P-選擇素調控具靶向多功能陰離子奈米載體包覆雙嘧達莫或白蛋白具有遠紅外光可觸發的熱療溫度/藥物釋放的聯合療法做為臨床應用(3/3)

  Chuang, E.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 有機/無機混成奈米複合材料發展智慧型藥物傳輸系統以治療p53失效腫瘤之探討與評估

  Cho, E.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫三：運用跨模態多項次神經影像技術探討神經調控模式對脊髓損傷者之神經可塑性與功能變化(3/3)

  Chan, W. P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新穎表觀遺傳調控作為缺氧性口腔癌標靶-探討LncRNA-KDM4 axis在缺氧性口腔癌之角色(3/3)

  Kung, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在動物模式下發展穿顱干擾波電刺激新技術應用於中風膀胱功能障礙復健治療(2/3)

  Peng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 護理引導簡短失眠行為療法對睡眠、情緒與認知功能之成效： 以恢復期頭部外傷病患進行模式建立與應用(1/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究第14 腫瘤壞死因子（TNFSF14）對粥狀動脈硬化進展、血管內皮功能及心血管疾病之影響– 從基礎到臨床

  Hsu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以社交溝通障礙相關的神經影像基礎開發泛自閉症症候群幼兒早期輔助診斷影像標誌與療育成效影像預測指標

  Lo, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lycium Barbarum Polysaccharides and Capsaicin on the Healing of Ulcerative Colitis-Mechanisms of Antioxidation, Anti-Inflammation, Anti-Apoptosis, Analgesic Activity, Intestinal Permeability, Cytoprotection, and Microbiota Regulation(3/3)

  Chao, J. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血清轉位蛋白TSPO作為診斷標記及神經元損傷指標合併發炎反應對認知功能機制探討(1/3)

  Bai, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討EZH2在嚴重氣喘中媒介纖維化蛋白表現及呼吸道纖維化之機轉(2/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以機轉與目標為導向開發天然抗病毒活性物質作為新興黃病毒感染之預防與治療藥物(1/3)

  Lin, L. T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(2/3)

  Chen, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(2/3)

  Ho, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不同脂肪酸組成的植物油對停經後肌肉萎縮之影響-以肌腸軸、胰島素阻抗及粒線體功能觀點進行探討

  Chiu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以腸肝腦軸探討魚油對於長期攝取酒精大鼠腦損傷之影響：由脂質代謝及胰島素抗性、免疫發炎反應以及氧化壓力等途徑探討EPA和DHA的腦部保護作用(1/3)

  Yang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology