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• b - Ministry of Science and Technology

  Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion

  Chen, H.

  8/1/11 → 11/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring Gene-Lifestyle Factors of Childhood Obesity, Pubertal Development, and Insulin Resistance(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Somatosensory Circuitry through Brain Science and Linguistics(1/2)

  Lin, J.

  6/1/19 → 5/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Constructing an Assessment Model for Outcome after Carotid Stent Using National Health Insurance Database with Validation by Clinical Data

  Chiu, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, S.

  12/1/17 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lycium Babarum Polysaccharides and C-Phycocyanin on Healing of Ethanol- or Drug-Induced Gastric Ulcer

  Chao, J. C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of Polymorphisms and Expressions in Genes of Omega-3 Fatty Acid Metabolism Enzymes in the Patients with Major Depressive Disorder

  Huang, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Machine Learning Technique to Evaluate the Impact of Curcumin on the Brain-Gut Interaction in Patients with Tuberous Sclerosis Complex Comorbid to Autism Spectrum Disorders(2/3)

  Lo, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development a Tissue-Like Block by Novel Porous Calcium Phosphate Combined Dental Pulp Stem Cells and Platelets Rich Fibrin for Bone Regeneration in Large Bony Defect

  Lee, S. & Yang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Clinical Evaluation of an Oligonucleotide Array for Detection of First- and Second-Line Drug Resistance of Mycobacterium tuberculosis Complex in a Northern Taiwan Medical Center (I)

  Yu, M.

  3/1/15 → 2/29/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Systematic Characterization and Analysis of the Landscape and Regulation of Rna Editing in Human Cancers

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Endothelial-To-Mesenchymal Transition in Arteriovenous Fistula Neointimal Hyperplasia

  Sue, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pomalidomide對腦創傷後引發急性肺損傷的治療效果可藉由調控自噬作用

  Wang, J.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C., Huang, S. & Lu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )

  Chen, S.

  9/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Power-Assisted Rehabilitation Device with Electrical Stimulation---Brige from Engineering to Clinical Trials

  Chen, S.

  9/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the cerebral perfusion changes in patients with mild traumatic brain injury using 3D bSSFP arterial spin labeling MRI

  Liu, H., Tsai, P., Chen, C. & Lu, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Activation of Adenosine A3 Receptors Suppresses Airway Hypersensitivity

  Lin, Y. & Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食安風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養甜味劑暴露之評估及其對脂肪組織的影響(1/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺俄(RU)雙邊協議型擴充加值(add-on) 國際合作研究計畫－汞與二價金屬交互作用對肥胖及肥胖相關鐵代謝異常之關聯(2/3)

  Chang, J.

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習來預測細胞表面蛋白並應用單細胞轉錄體之功能分類鑑別

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 脂肪激素內脂素對子宮肌瘤增生及微環境影響:分子機制探討及精準營養應用之研究(2/3)

  Hsia, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

  Peng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation(3/3)

  Chan, W. P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究(3/3)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fabrication of Endometrial Cell Sheet for Fertility Resumption by a Transgenic Mouse Model

  Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Biosafety and Preclinical Efficacy Evaluation of Orthopedic Implant with PRP Combination

  Tseng, C.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment

  Lee, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Chemo-Sensitizer Conjugated Carbon Nanotubes as a Novel Cancer Therapeutical Delivery System

  Cho, E.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(2/3)

  Hsiao, G.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Resveratrol Supplementation and Exercise Training on Skeletal Muscle Mass, Muscle Damage, and Exercise Performance-Ⅱ

  Kan, N.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以失智症與照顧者為主體建置智慧輔助科技整合照護平台(重點主題：A1/A2)(2/2)

  Chen, S.

  6/1/20 → 5/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Evaluation of Interactive Cognitive Function Training Program (ICFTP) on Elders’ General Cognitive Functions, Executive Functions, and Vi Suo-Motor Abilities---A Randomized Controlled Study(3/3)

  Chou, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Glutamine on the Inflammatory Response and Tissue Injury in a Hindlimb Ischemic Reperfusion Mice Model

  Yeh, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Manipulating Neural Oscillations in Frequency and Phase Shifting Using Transcranial Alternating Current Stimulation: an Investigation into the Oscillatory Neural Mechanisms of Visual Working Memory

  Tseng, P.

  12/1/17 → 11/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 死亡體驗教育對醫護學生之生死態度影響探究

  Han, D.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of N-3 Polyunsaturated Fatty Acids on the Gut Microbiota in Depressive Disorder

  Huang, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Regulation of Macrophage Polarization and Disease Progression with Specific Haptoglobin Phenotypes in Patients with Chronic Obstructive Pulmonary Disease

  Ho, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pupillometry in Vision, Arousal and Cognition: an Integrated Approach Using Oculomotor and Autonomic Responses, Brain Stimulation, and Computational Modeling(1/5)

  Wang, C.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study of the Trismus Condition of Patients with Head and Neck Cancer Who Have Undergone Concomitant Chemoradiotherapy and the Preventive Effect of Oral Rehabilitation on Trismus

  Jeng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prevalence of Metabolic Dysregulation and Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-Treated Schizophrenic Patients

  Chen, C. & Lu, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation: an in vivo Transgenic Mouse Model (II)

  Chen, C., Tzeng, C. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討海馬迴神經與膠質細胞交互作用於腦創傷後長期認知後遺症之機制作為藥物治療之契機

  Wang, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms of Apelin in Electrophysiological Characteristics and Calcium Dynamics in Left Atrium and Pulmonary Vein Cardiomyocytes Underlying the Pathophysiology of Atrial Fibrillation

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Nanocomposite Films and Doping Techniques for Improving the Practicality of Flexible Perovskite Solar Cells

  Chang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology