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  吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(2/3)

  Sheu, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討B型肝炎相關肝癌中HBx蛋白與其相關之表觀遺傳調控因子促進SENP1表現與癌幹細胞特性：HBx/SENP1之角色與臨床意義(3/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不孕症婦女心理困擾變化軌跡：身心療癒措施結合心率變異生理回饋之成效與機轉(3/3)

  Kuo, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對PD-L1 表現機制所發展出之口腔癌治療策略(2/3)

  Lin, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 早幼粒細胞白血病鋅指蛋白(PLZF)對腦部發育的多重功能之探討(3/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制site-1蛋白酶引發肝癌細胞自我吞噬之研究

  Yang, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制NLRP3發炎體- 糖尿病心肌病變的治療新策略

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(1/3)

  Lu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在國際健康功能與身心障礙分類系統的架構下，探討蛋白質補充合併運動訓練對急慢性機構衰弱老人改善肌少症指數及身體活動功能之成效(2/3)

  Liou, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 纖維細胞生長因子與其受體之訊息路徑在急性腎損傷中維持腎臟血管結構能力之角色研究

  Cheng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ZFHX3 knockdown調控心房纖維化導致心房顫動病理性結構重塑之機轉探討

  Kao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(1/3)

  Yang, C. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用輸卵管上皮類器官培養技術開發卵巢癌早期偵測之表基因生物標記(1/3)

  Lai, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討黃腐醇合併降血糖藥是否可調控粒線體失常並經由活化未摺疊蛋白反應所激發之AMPK-NRf2-ARE-Glo1路徑來逆轉雙羰基壓力導致之糖尿病腎脂毒性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(2/2)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 非洲史瓦帝尼王國引致癲癇之神經性犬蛔蟲症或神經性囊尾幼蟲症之分子流行病學、相關危險因子與蟲體親緣分析(2020-2023)

  Fan, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性結構天然物??衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討(1/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• CCR5標靶微脂粒包覆免疫抑制藥物Tacrolimus治療自體免疫疾病之研究(2/3)

  Liu, D.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(1/2)

  Kuan, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(1/3)

  Tzeng, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Chemical Synthesis of Cancer-Associated Glycoproteins( I )

  Hsieh, Y.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過感恩行為影響學生在大體解剖學實驗課程中的情緒感受與調適並強化家訪的效果

  Chiou, R.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞受體專一性RNA適體奈米質粒誘發第三型玻尿酸合成酵素的抗癌機制探討(1/3)

  Tu, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(3/3)

  Chao, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 多體學量測平台探討微環境動態變化：以調控脂肪細胞可塑性為例

  Chang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性腎臟病之日夜週期失序(1/3)

  Wu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以靜磁場刺激臍帶間葉幹細胞所釋放的細胞外囊泡作為促進牙髓幹細胞分化成類牙本質細胞之研究

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 合成可雙重抑制組織蛋白去乙醯酶6與熱休克蛋白90，並同時調節PD-L1之雜環類抗癌化合物

  Lai, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討非選擇性與選擇性組蛋白去乙醯?抑制劑與免疫檢查點抑制劑合併治療之效用及其機轉(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討脯氨酸循環調控癌細胞代謝重組與腸道菌群在胰腺癌吉西他濱抗藥性中的作用

  Huang, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具有靶向及溶解血栓功能的奈米藥物治療平台(1/2)

  Mi, F.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• CXCL6/CXCL1 axis在PDK1訊號路徑介導的放射抗性肝細胞癌之分子機制探討

  Tsai, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-以機器學習的方法導入影像基因圖譜用以研究膠質母細胞瘤與免疫相關之基因表現(2/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Etelcalcetide經由調控Nrf2和Klotho-AMPK路徑改善腎性骨病變的骨轉換、血管鈣化和腎臟纖維化

  Zheng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 住院急性胰臟炎使用鴉片類處方藥物病人之持續性使用分析

  Chen, S. H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(2/3)

  Jung, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嗜伊紅性白血球陽離子蛋白衍生之細胞穿透胜肽對於調節過敏性發炎之研究- 促進STAT-6反義RNA之運送與表現(2/3)

  Lee, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略(2/3)

  Kuo, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 台灣肝硬化病人使用抗膽鹼藥物與發生肝性腦病變之風險評估(1/3)

  Wu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 遠紅外線改善線粒體功能對糖尿病小鼠胰島β細胞的保護作用及與SIRT1和PLZF相關機制的研究(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫色桿菌素之微生物綠色醱酵製程開發與應用

  Lin, S.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺灣食用油與含油食品縮水甘油酯含量調查與形成機制研究(2/3)

  Lee, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 行人低頭族風險行為探討: 以虛擬擴增實境遊戲、賽車遊戲為例

  Pai, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用機器學習演算法透過基因體資訊挖掘未知基因的功能與預測細菌抗藥性(2/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(1/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-花生四烯酸的代謝在Sp1對神經膠質瘤與肺癌抗藥性的陰陽作用中扮演的角色(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Omega-3脂肪酸合併褪黑激素致效劑改善憂鬱症狀與生物日夜週期機制之探討： 一項營養與精神醫學之轉譯研究(1/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究-探討青少年期慢性睡眠剝奪對壓力調適功能之影響--以腸腦軸線功能變化為例(2/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology