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  Tumor Microenvironment Induced Egfr-Tki Resistance

  Feng, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 附基因調控對心房病變引發左右心房纖維母細胞鈣離子流恆定與纖維化特性差異之機轉

  Chung, C.

  8/1/17 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms

  Hung, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Angiopoietin-Like Protein 1 in Sorafenib Resistance and Cancer Stemness of Hepatocellular Carcinoma Cells

  Huang, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Platelets and Platelet-Derived Microparticles For“Trojan Horse” Cancer Therapy (Thct)

  Burnouf, T. P. R.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Molecular Biological Mechanism of Fish Oil on Preventing Alcoholic Liver Diseases: the Hepatoprotective Effects of Epa and Dha Based on Lipid Metabolism, Autophagy and Inflammatory Responses

  Yang, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Environment-Sensitive Chitosan Nanomicelles for Ph-Jump Activation, Oxygen Evolution and Anticancer Drug Delivery

  Mi, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of N-3 Polyunsaturated Fatty Acids on the Gut Microbiota in Depressive Disorder

  Huang, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prescribing Patterns and Guideline Adherence for Meperidine Use in Taiwan

  Chen, S. H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Single-Cell Nf-Kb Dynamics for Modeling Tnf-Α Signaling Circuits

  Yang, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glutamate Receptor as a Therapeutic Target in Recurrent Glioma: Patient-Derived Glioma Xenograft Model

  Shen, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-H and Plc-Delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation the Cotherapeutic Ginkgo Biloba Plus Metformin against the Methylglyoxal-Induced Renal Tubular Lipotoxicity and Cellular Senescence in Cell Cycle via Srebp and Ppar Pathways

  Peng, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Highly Efficient Vi Ral Pseudoparticle Platform for the Identification of Novel Hepatitis C Vi Rus Entry Inhibitors

  Lin, L. T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Study of the Mechanisms and Therapeutic Effects of Ssri Antidepressants on Melanoma

  Lee, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Roles of Unfolded Protein Response and Ubiquitin-Proteasome System in Radiotherapy Using Nanoparticle Drug Delivery in Triple-Negative Breast Cancer

  Chiu, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sorafenib抗藥性所誘發之肝癌惡病質與癌幹細胞特性之細胞療法：利用全身安全性之人類胎盤蛻膜間葉幹細胞標靶TNFα-IL6之免疫調控與攜帶奈米藥物對抗Sorafenib抗藥性肝癌之雙功能策略(先期補助)

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• 幹細胞基礎研究、前臨床動物試驗與臨床試驗

  Huang, Y.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy

  Tsai, K. K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Aldose Reductase and Nf-Kb Signalings in Collagen Receptor Glycoprotein Vi-Mediated Platelet Autophagy: a Regulatory Mechinary of Endogenous Gaba in Anucleate Blood Cells

  Sheu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Oncogenic Role and Targeted Therapeutic Potential of Alpha 9 Nicotinic Acetylcholine Receptors on Breast Cancers: Emphasizing in Pre-Clinical Assessment of Biphasic Antibody Nano-Drugs in Xenografts( I )

  Chang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Chronic Intake of High-Lipid/High-Cholesterol Diet and Ketogenic Diet on Bbb, Insulin Metabolism, Cholesterol Homeostasis, and Ad Related Features in Mice

  Lin, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Efficient Immunoglobulin G Analytical Method for Investigating Autoantibody Biomarkers for Pancreatic Disease (Continuous Research)

  Tsai, I.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Encapsulated Cell Therapy via a Novel Microtube Array Membrane Encapsulated Hybridoma for Cancer Immunotherapy

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development and Characterization of Zein-Sodium Caseinate Nanoparticles-Hydrogel Composite for Localized and Sustained Sirna Delivery

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Hdac6-Mediated Sp1 Deacetylation in the Evolution of Acquired Temozolomide Resistance in Glioblastoma

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子化合物開發新穎且具選擇性塗藥用於血管支架(先期補助)

  Huang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Studies of the Vegetable Components on Menopausal Obesity and the Associated Mechanisms

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploiting Acridine Scaffold to Develop Novel Anticancer Agents Based on a Dual Target Strategy

  Huang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Decellularized Plant Extracellular Matrices as a Scaffold for Tissue Engineering

  Tseng, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Assessment of Bone Healing Capacity and Osseointegration Potential of Bone Grafting Materials Loaded with Rabbit Mesenchymal Stem Cells Derived from Different Sources: in Vitro and in Vivo Studies

  Feng, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Human Blood Plasma-Photosensitizer-Conjugated Nanocomplex for Selectively Killing Colon Cancer via Locally Photodynamic/Photothermal Therapy

  Chuang, E.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Pctk1 in the Progression of Colorectal Cancer and Molecular Mechanism

  Wei, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pharmacological Investigations and the Study of the Potential Biological Effects of Nitric Oxide Releasing Nano-Carrier System in Blue Light Induced Retinopathy( I )

  Cheng, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腦血流調控功能在腦血管疾病及神經退化性疾病的角色及應用

  Chiou, H.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer( I )

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Diagnostic and Prognostic Biomarker for Acute Stroke in Serum Translocator Protein (Tspo) and the Related Association with Neuro-Inflammation

  Bai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impacts of Sirtuin Related Genes and Aging Related Factors on the Risk of Early-Onset Ischemic Stroke

  Hsieh, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• ≫Combination of E1a Gene Therapy and Egfr Tyrosine Kinase Inhibitors in Tnbc: Preclinical Studies May Light up the New Therapeutic Strategy

  Su, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電腦輔助ASPECTS於急性缺血性腦中風病人評估

  Chan, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用肉毒桿菌避免唇顎裂患者患側鼻孔變寬-2

  Chen, K.

  8/1/17 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Personzliaed Periodontal Disease Prevention

  Chen, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Differentiation of Literati-Gentry Strata and the Construction of Citizenship in the Late Qing Dynasty and the Early Republican Period: a Cultural Pragmatics Approach

  Tsai, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 鑑定癌症幹細胞抑制劑(3/3)

  Whang-Peng, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Multi-Modal Investigation of the Biochemical Correlates of the Temporal Structure of Neural Activity

  Duncan, N. W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology