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• 利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 基於深度學習與機器學習混合分析多體學數據於癌症精準醫學治療之應用評估(2/2)

  Chang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(3/3)

  Sheu, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以IgA1 O-聯結醣基為標靶開發IgA腎病變之診斷試劑重塑臨床評估之準則(3/3)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對熱休克蛋白70-葡萄糖調節蛋白78驅動癌幹細胞之路徑以克服髓母細胞瘤對常規化學療法的抗藥性

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 後生元和益生菌透過抑制炎症和調節免疫力減輕新生小鼠高氧誘導的肺損傷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lycium Barbarum Polysaccharides and Capsaicin on the Healing of Ulcerative Colitis-Mechanisms of Antioxidation, Anti-Inflammation, Anti-Apoptosis, Analgesic Activity, Intestinal Permeability, Cytoprotection, and Microbiota Regulation(3/3)

  Chao, J. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具化學/光熱複合療效及骨組織修復功能之奈米粒子應用於發生骨轉移之乳癌治療(2/3)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(3/3)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對IL-33/ST2訊息路徑調控鈣平衡、內質網壓力與粒線體功能作為心房與肺靜脈心律不整活性與心房顫動致病機轉及治療策略探討(2/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者單核球和巨噬細胞活化與血管粥狀化的關聯性: 頸動脈超音波的個案對照研究(1/3)

  Tsai, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討膠質母細胞瘤外泌體中Btk/PD-L1/PD-L2 訊號途徑在腫瘤免疫所扮演的致病角色及其精準治療應用

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白?體之機制(1/3)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Acceptance and Commitment Therapy (Act) on Internalized Stigma and Low Self-Esteem among Patients with Schizophrenia

  Chung, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發透明質酸基奈米藥物以增強後眼部藥物遞送效能及應用於藍光誘導損傷之視網膜病變治療(II）(1/2)

  Tseng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以尿?雙磷酸葡萄糖醛酸基轉移?2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(2/3)

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(3/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ACSL1/FASN訊號軸調控脂質代謝重編程在泌尿道上皮癌化學/免疫治療抗性和轉移所扮演的角色與新穎治療策略的開發

  Wu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 酵素交聯水凝膠合併血小板裂解質應用於關節軟骨再生(1/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索蝦急性肝胰腺壞死病毒素 PirAvp 與 PirBvp 之活化機制與中和策略(2/3)

  Wang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 真實世界數據應用於風險評估設定醫療照護模式以提昇住院照護品質研究-方法建立與導入實施(1/2)

  Chen, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長期尿道出口阻塞透過膠原蛋白 I 沉積而降低膀胱順應性-針灸治療的潛在標的

  Lin, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 不同脂肪酸組成的植物油對停經後肌肉萎縮之影響-以肌腸軸、胰島素阻抗及粒線體功能觀點進行探討

  Chiu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子甲殼素奈米粒子建構水生魚類的核酸運輸平台

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發循環腫瘤細胞類器官晶片於大腸直腸癌藥物研發

  Chiou, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內 T 細胞於腫瘤微環境抗癌功效之創新協同療法-發展新型聚乙二醇-免疫增敏奈米藥物載體以毒殺大腸癌並強化腫瘤區域T細胞之抗癌功效(2/3)

  Liu, D.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可標靶樹突細胞之負載新型冠狀病毒棘狀蛋白的醣化PLGA奈米顆粒在小鼠中引起有效的免疫原性之研究

  Sheu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 具機械強度、可降解及骨誘導能力之鎂基非晶質合金應用於高位脛骨截骨矯正術之骨填充楔開發(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 從食品風險暴露之角度探討非營養性甜味劑對女性生殖狀況之影響-非營養性甜味劑對子宮收縮及生殖細胞之影響效應及相關機轉探討(2/3)

  Hsia, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究-青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:健康青少年族群之觀察追蹤與介入研究(3/3)

  Lee, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(2/3)

  Chien, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 結合數位學習和自主學習法之跨領域資訊專題實作

  Su, E. C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 以腸肝腦軸探討魚油對於長期攝取酒精大鼠腦損傷之影響：由脂質代謝及胰島素抗性、免疫發炎反應以及氧化壓力等途徑探討EPA和DHA的腦部保護作用(1/3)

  Yang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 魚類感覺系統在酸性環境下的功能變化-從側線到行為的探討(1/3)

  Horng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討慢性阻塞性肺病受類Toll受體活化調控長鏈非編碼核醣核酸的角色(3/3)

  Wu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Local Circadian Clock Regulation of Fluid Barriers to the Brain

  Myung, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(2/2)

  Kuan, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Post-Stroke Vi Sual Dependence and Early Intervention of Multisensory Balance Rehabilitation (3/3)

  Lee, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TDP-43蛋白在神經細胞中功能及在神經退化疾病上角色的基礎與轉譯研究(3/3)

  Shen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The impact of technology-enhanced projected-based learning applied in Introduction to Research on self-efficacy

  Yen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• (教學實踐) 以虛擬實境方式強化[食品法規與管理]的實務應用教學

  Yang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• The Choroid Plexus as a Hub of Immune-Clock Interaction That Connects the Body to the Brain in Prematurity (2/3)

  Myung, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合深度學習及數據非依賴採集質譜法以偵測膜蛋白體突變與癌症新生抗原(1/3)

  Han, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 裝載GM-CSF及標靶奈米粒子疫苗之水膠複合系統用於原位募集並活化樹突細胞以增強腫瘤特異性免疫反應達到抑制癌症轉移之功效(1/3)

  Pan, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以化學分子網絡探索清熱藥之抗炎代謝組成

  Lai, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過非監督式微生物群基因體分類工具深度挖掘與分析微生物如何影響疾病的產生(1/3)

  Wu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology