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• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Innate Immune Modulator---Molecular Characterization of Bupleurum kaoi Polysaccharide Fraction and Assessment of Its Immunomodulatory and Antiviral Effects

  Lin, L. T.

  11/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Power-Assisted Rehabilitation Device with Electrical Stimulation---Brige from Engineering to Clinical Trials

  Chen, S.

  9/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 同步輻射X光合成奈米銀修飾複合材料顆粒及其應用

  Lin, C.

  11/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Translational Genomic Approaches in Endometriosis

  Tzeng, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Surgical Decision-Making Process, Providing Information on the Decision-Making Process, the Impact of Physical and Mental Health for Spinal Surgery Patients

  Lin, P.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Use of Blood Protein Fractions in Translational Therapy

  Burnouf, T. P. R.

  11/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Functional Role of Podocalyxin-Like 1 in Regulation of Stemness and Metastasis of Breast Cancer and Cancer Stem Cells---Evaluation the Potentiality for Cancer Targeting Therapy

  Lin, C.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Expressing Membrane Antibody Reporter in the Islet Cells of Nonobese Diabetic Mice to Noninvasive Image the Disease Progression of Autoimmune Diabetes and the Therapeutic Effects of Drugs or Transgenes

  Chuang, K.

  11/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Policy Analysis of Shimen Watershed Area Management---An Environmental Governance Perspective (I)

  Lin, Y.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Build of Functional Protein Molecular Shuttles by Using a Genetically Engineered Kinesin and Nucleic Acid Aptamers - with the Integration of the Cost-Effective Microscopic Imaging System and Micro Fluidic Channel Chips

  Kuo, T.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of miR-1 in RAS Mutation Prostate Cancer Metastasis

  Liu, Y.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the MicroRNA-128-Mediated Signaling Pathways in Glioblastoma Multiforme Formation

  Chen, K.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

  8/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 肺炎病人呼氣鑑別診斷

  Shih, C.

  10/25/13 → 11/20/13

  Project: A - Government Institution › f - Other (Funded by Government)

• Potential of Capsaicin against Advanced Glycation Endproducts Formation

  Wu, C.

  12/1/12 → 11/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Multi-Organ Damage in Heatstroke-Induced Rats

  Wang, Y.

  12/1/12 → 11/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用行動通訊技術協助西藏地區之醫護人員進行遠距醫療照護之藍圖規畫

  Li, Y.

  5/24/13 → 11/30/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 建置健保法學知識數位平台

  Yang, C.

  6/7/13 → 12/6/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 職場生物氣膠暴露及建議值調查評估研究

  Chao, H. J.

  6/11/13 → 12/13/13

  Project: A - Government Institution › f - Other (Funded by Government)

• Functional Evaluation of Cnidii Fructus and Osthole on Endothelial Progenitor Cells by Animal and Cell Models(2-1)

  Hou, W. & Huang, C.

  1/17/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 成人預防保健服務尿酸、血液常規項目效益分析計畫-102年度後續擴充

  Bai, C.

  2/5/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• The Risk Evaluation and Management of Herbs Contraindicated in Pregnancy

  Chien, S.

  5/20/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Establish a E-learning platform for Clinical Application of Chinese Medicine

  Wang, C.

  1/23/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Comparative studies of Tao-Ren-Cheng-Qi Tang or San-Huang-Xie-Xin Tang with aspirin on neuroprotection and lowering the neurobehavioral deficits in rat ischemic stroke: evaluation the risks of inducing gastric bleeding, intracerebral hemorrhage, and subarachnoid hemorrhage (2-2)

  Sheu, J.

  1/21/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 102年度社區整合式篩檢暨肝癌高危險群巡迴篩檢服務教育訓練及成果評價計畫

  Chen, L.

  5/9/13 → 12/16/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 102年度特定行業別職場健康促進輔導計畫-住宿及餐飲業

  Chen, R.

  4/25/13 → 12/16/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 建立服務業職場友善健康管理模式

  Chen, C.

  5/21/13 → 12/20/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 奈米金屬微粒暴露引發勞工心血管效應之細胞毒理評估

  Chuang, K.

  6/27/13 → 12/20/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 原住民幸福調查-調查指標訂定

  Lyu, S.

  10/25/12 → 12/25/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 102年度臺北市輻射屋居民健康照護需求評估工具建立

  Chiu, C.

  7/16/13 → 12/31/13

  Project: A - Government Institution › f - Other (Funded by Government)

• Chinese Herbal Compound Extract of Pig Sperm Detection and Activation of the Pharmacokinetic Evaluation and Preparation of R &Amp; D

  Lee, C.

  8/1/12 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B29

  Liao, Y.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Integrated Therapeutic Strategy Using Ginkgo Biloba and Exercise to Improve Muscle Wasting of Different Origin

  Peng, C.

  8/1/12 → 12/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 102年台北市立聯合醫院忠孝院區員工體適能檢測計畫

  Kan, N.

  8/1/13 → 12/31/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 結合電腦輔助藥物設計與體外實驗來開發新型5α還原酶抑制劑

  Ho, Y.

  1/1/13 → 12/31/13

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 探討鐵質過量對於脂肪肝病變(C型肝炎及非酒精性脂肪肝)及葡萄糖代謝的影響

  Chang, J.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B22

  Cheng, C.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 探討尼古丁接受器在胃癌化學治療上的角色及其作用機制

  Wang, W.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B23

  Chen, K.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B19

  Lee, K.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• More healthy teas innovatively treated utilizing gold nanoparticles

  Liu, Y.

  1/1/13 → 12/31/13

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 102年度「醫療產業先進設備人才培育資源中心 (含牙科材料設備及研發人才)」

  Ou, K.

  1/1/13 → 12/31/13

  Project: A - Government Institution › d - Ministry of Education

• 數位多媒體互動技術於手腕復健訓練之研究

  Chen, S.

  1/1/13 → 12/31/13

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Longitudinal Outcomes, Bone Density, and Tai Chi Exercise in Older Fallers

  Lin, M.

  1/1/13 → 12/31/13

  Project: A - Government Institution › a - National Health Research Institutes

• 含碘-鉑之奈米載體做為肺癌診斷之治療試藥之開發

  Tseng, C.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU101-AE1-B12

  Lin, L. T.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 含鈦類鑽碳薄膜之合成、特性及應用於植入式人工關節之研究

  Lee, J.

  1/1/13 → 12/31/13

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 臺灣人體生物資料庫子宮內膜異位症之生物標誌研發

  Tzeng, C.

  3/26/13 → 12/31/13

  Project: A - Government Institution › f - Other (Funded by Government)

• 健康促進國際政策及學術資料建置計畫

  Chang, W.

  7/3/13 → 12/31/13

  Project: A - Government Institution › c - Ministry of Health and Welfare